Published in Genes Dev on January 15, 2012
Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs): post-transcriptional drivers of cancer progression? Cell Mol Life Sci (2012) 1.68
Loss of Stromal IMP1 Promotes a Tumorigenic Microenvironment in the Colon. Mol Cancer Res (2015) 1.44
Keratins control intercellular adhesion involving PKC-α-mediated desmoplakin phosphorylation. J Cell Biol (2013) 1.09
mRNA on the move: the road to its biological destiny. J Biol Chem (2013) 0.99
IMP1 promotes tumor growth, dissemination and a tumor-initiating cell phenotype in colorectal cancer cell xenografts. Carcinogenesis (2013) 0.92
Stress granules are dispensable for mRNA stabilization during cellular stress. Nucleic Acids Res (2014) 0.89
IGF2BP1: a post-transcriptional "driver" of tumor cell migration. Cell Adh Migr (2012) 0.86
Tumour promoting and suppressing roles of the atypical MAP kinase signalling pathway ERK3/4-MK5. J Mol Signal (2012) 0.86
IGF2BP1 promotes mesenchymal cell properties and migration of tumor-derived cells by enhancing the expression of LEF1 and SNAI2 (SLUG). Nucleic Acids Res (2013) 0.82
MicroRNA-873 (miRNA-873) inhibits glioblastoma tumorigenesis and metastasis by suppressing the expression of IGF2BP1. J Biol Chem (2015) 0.82
miRNA-196b inhibits cell proliferation and induces apoptosis in HepG2 cells by targeting IGF2BP1. Mol Cancer (2015) 0.82
Two Isoforms of the RNA Binding Protein, Coding Region Determinant-binding Protein (CRD-BP/IGF2BP1), Are Expressed in Breast Epithelium and Support Clonogenic Growth of Breast Tumor Cells. J Biol Chem (2015) 0.81
Involvement of the mRNA binding protein CRD-BP in the regulation of metastatic melanoma cell proliferation and invasion by hypoxia. J Cell Sci (2012) 0.81
Molecular insights into the coding region determinant-binding protein-RNA interaction through site-directed mutagenesis in the heterogeneous nuclear ribonucleoprotein-K-homology domains. J Biol Chem (2014) 0.80
A novel role for atypical MAPK kinase ERK3 in regulating breast cancer cell morphology and migration. Cell Adh Migr (2015) 0.79
Control of cell migration through mRNA localization and local translation. Wiley Interdiscip Rev RNA (2014) 0.79
The oncogenic triangle of HMGA2, LIN28B and IGF2BP1 antagonizes tumor-suppressive actions of the let-7 family. Nucleic Acids Res (2016) 0.79
XPO1/CRM1 Inhibition Causes Antitumor Effects by Mitochondrial Accumulation of eIF5A. Clin Cancer Res (2015) 0.78
Cross-Phosphorylation and Interaction between Src/FAK and MAPKAP5/PRAK in Early Focal Adhesions Controls Cell Motility. J Cancer Biol Res (2014) 0.78
Integrated analysis of global mRNA and protein expression data in HEK293 cells overexpressing PRL-1. PLoS One (2013) 0.77
Long-term reduction of T-cell intracellular antigens leads to increased beta-actin expression. Mol Cancer (2014) 0.77
Distinct Impact of Two Keratin Mutations Causing Epidermolysis Bullosa Simplex on Keratinocyte Adhesion and Stiffness. J Invest Dermatol (2015) 0.77
Tudor staphylococcal nuclease: biochemistry and functions. Cell Death Differ (2016) 0.76
mRNA fate: Life and death of the mRNA in the cytoplasm. RNA Biol (2013) 0.76
Homology modeling and ligand docking of Mitogen-activated protein kinase-activated protein kinase 5 (MK5). Theor Biol Med Model (2013) 0.76
LY6E: a conductor of malignant tumor growth through modulation of the PTEN/PI3K/Akt/HIF-1 axis. Oncotarget (2016) 0.75
Comparative molecular dynamics simulations of mitogen-activated protein kinase-activated protein kinase 5. Int J Mol Sci (2014) 0.75
A Novel IMP1 Inhibitor, BTYNB, Targets c-Myc and Inhibits Melanoma and Ovarian Cancer Cell Proliferation. Transl Oncol (2017) 0.75
Dicer loss and recovery induce an oncogenic switch driven by transcriptional activation of the oncofetal Imp1-3 family. Genes Dev (2017) 0.75
IGF2BP1: a novel binding protein of p38 MAPK. Mol Cell Biochem (2017) 0.75
Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzeta. Cell (2001) 7.07
Sequences responsible for intracellular localization of beta-actin messenger RNA also affect cell phenotype. J Cell Biol (1994) 6.33
Spatial regulation of beta-actin translation by Src-dependent phosphorylation of ZBP1. Nature (2005) 5.29
Characterization of a beta-actin mRNA zipcode-binding protein. Mol Cell Biol (1997) 5.21
PTEN and the PI3-kinase pathway in cancer. Annu Rev Pathol (2009) 4.83
A Rac switch regulates random versus directionally persistent cell migration. J Cell Biol (2005) 4.40
Asymmetrical beta-actin mRNA translation in growth cones mediates attractive turning to netrin-1. Nat Neurosci (2006) 3.74
An essential role for beta-actin mRNA localization and translation in Ca2+-dependent growth cone guidance. Nat Neurosci (2006) 3.30
The regulation of cell motility and chemotaxis by phospholipid signaling. J Cell Sci (2008) 3.04
MAPKAP kinases - MKs - two's company, three's a crowd. Nat Rev Mol Cell Biol (2006) 2.80
Chemotaxis in the absence of PIP3 gradients. Curr Biol (2007) 2.73
Neurotrophin-induced transport of a beta-actin mRNP complex increases beta-actin levels and stimulates growth cone motility. Neuron (2001) 2.57
VICKZ proteins: a multi-talented family of regulatory RNA-binding proteins. Biol Cell (2005) 2.41
How and why does beta-actin mRNA target? Biol Cell (2005) 2.38
RNA-binding IMPs promote cell adhesion and invadopodia formation. EMBO J (2006) 2.34
The MK5/PRAK kinase and Myc form a negative feedback loop that is disrupted during colorectal tumorigenesis. Mol Cell (2011) 2.17
The Rho-mDia1 pathway regulates cell polarity and focal adhesion turnover in migrating cells through mobilizing Apc and c-Src. Mol Cell Biol (2006) 2.11
Heat shock protein 27 phosphorylation: kinases, phosphatases, functions and pathology. Cell Mol Life Sci (2009) 2.09
Micromanagers of malignancy: role of microRNAs in regulating metastasis. Trends Genet (2008) 2.03
Phosphoinositide 3-kinases in cell migration. Biol Cell (2009) 1.95
Actin cytoskeleton and small heat shock proteins: how do they interact? Cell Stress Chaperones (2002) 1.84
ZBP1 regulates mRNA stability during cellular stress. J Cell Biol (2006) 1.84
Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs. RNA (2008) 1.63
MicroRNAs: Crucial multi-tasking components in the complex circuitry of tumor metastasis. Cell Cycle (2009) 1.63
The involvement of a conserved family of RNA binding proteins in embryonic development and carcinogenesis. Gene (2002) 1.60
Atypical mitogen-activated protein kinases: structure, regulation and functions. Biochim Biophys Acta (2006) 1.56
Involvement of Akt in neurite outgrowth. Cell Mol Life Sci (2009) 1.48
Metastasis: tumor cells becoming MENAcing. Trends Cell Biol (2010) 1.44
Activation of MK5/PRAK by the atypical MAP kinase ERK3 defines a novel signal transduction pathway. EMBO J (2004) 1.43
Regulation of c-myc mRNA decay by translational pausing in a coding region instability determinant. Mol Cell Biol (2002) 1.43
Phosphorylation of zipcode binding protein 1 is required for brain-derived neurotrophic factor signaling of local beta-actin synthesis and growth cone turning. J Neurosci (2010) 1.29
Characterization of the atypical MAPK ERK4 and its activation of the MAPK-activated protein kinase MK5. J Biol Chem (2006) 1.27
Anthrax lethal toxin paralyzes actin-based motility by blocking Hsp27 phosphorylation. EMBO J (2007) 1.25
Cellular responses to extracellular guidance cues. EMBO J (2010) 1.25
The RNA-binding protein Vg1 RBP is required for cell migration during early neural development. Development (2003) 1.24
Expression of the RNA-binding protein IMP1 correlates with poor prognosis in ovarian carcinoma. Oncogene (2007) 1.23
Role of heat shock protein 27 in cytoskeletal remodeling of the airway smooth muscle cell. J Appl Physiol (1985) (2004) 1.22
PTEN plays a role in the suppression of lateral pseudopod formation during Dictyostelium motility and chemotaxis. J Cell Sci (2007) 1.21
Activation loop phosphorylation of the atypical MAP kinases ERK3 and ERK4 is required for binding, activation and cytoplasmic relocalization of MK5. J Cell Physiol (2008) 1.20
Regulation of MAPK-activated protein kinase 5 activity and subcellular localization by the atypical MAPK ERK4/MAPK4. J Biol Chem (2006) 1.16
14-3-3epsilon inhibits MK5-mediated cell migration by disrupting F-actin polymerization. Cell Signal (2007) 1.16
PKA-induced F-actin rearrangement requires phosphorylation of Hsp27 by the MAPKAP kinase MK5. Cell Signal (2009) 1.14
Small heat shock proteins in smooth muscle. Pharmacol Ther (2008) 1.13
ZBP1 enhances cell polarity and reduces chemotaxis. J Cell Sci (2007) 1.11
Modulation of F-actin rearrangement by the cyclic AMP/cAMP-dependent protein kinase (PKA) pathway is mediated by MAPK-activated protein kinase 5 and requires PKA-induced nuclear export of MK5. J Biol Chem (2007) 1.07
The use of insulin like-growth factor II messenger RNA binding protein-3 in diagnostic pathology. Hum Pathol (2010) 1.06
Heat shock proteins in breast cancer progression--a suitable case for treatment? Int J Hyperthermia (2010) 1.06
A role for VICKZ proteins in the progression of colorectal carcinomas: regulating lamellipodia formation. J Pathol (2008) 1.01
VICKZ proteins mediate cell migration via their RNA binding activity. RNA (2007) 0.99
Docking of PRAK/MK5 to the atypical MAPKs ERK3 and ERK4 defines a novel MAPK interaction motif. J Biol Chem (2009) 0.96
The Ser(186) phospho-acceptor site within ERK4 is essential for its ability to interact with and activate PRAK/MK5. Biochem J (2008) 0.94
HSPB1, actin filament dynamics, and aging cells. Ann N Y Acad Sci (2010) 0.93
Cell biology: silenced RNA on the move. Nature (2005) 0.91
Near-infrared (NIR) dye-labeled RNAs identify binding of ZBP1 to the noncoding Y3-RNA. RNA (2010) 0.91
Insulin-like growth factor II mRNA binding protein 1 associates with Gag protein of human immunodeficiency virus type 1, and its overexpression affects virus assembly. J Virol (2008) 0.85
Spatial regulation of PI3K signaling during chemotaxis. Wiley Interdiscip Rev Syst Biol Med (2010) 0.84
Thiolutin inhibits endothelial cell adhesion by perturbing Hsp27 interactions with components of the actin and intermediate filament cytoskeleton. Cell Stress Chaperones (2009) 0.83
Heat shock protein 27 in neuronal survival and neurite outgrowth. Biochem Biophys Res Commun (2009) 0.82
From silencing to gene expression: real-time analysis in single cells. Cell (2004) 7.73
Transcriptional pulsing of a developmental gene. Curr Biol (2006) 6.35
In vivo dynamics of RNA polymerase II transcription. Nat Struct Mol Biol (2007) 6.10
Single-RNA counting reveals alternative modes of gene expression in yeast. Nat Struct Mol Biol (2008) 6.09
Spatial regulation of beta-actin translation by Src-dependent phosphorylation of ZBP1. Nature (2005) 5.29
Single-cell gene expression profiling. Science (2002) 5.07
Dynamics of single mRNPs in nuclei of living cells. Science (2004) 4.58
Identification and testing of a gene expression signature of invasive carcinoma cells within primary mammary tumors. Cancer Res (2004) 4.04
Single cell behavior in metastatic primary mammary tumors correlated with gene expression patterns revealed by molecular profiling. Cancer Res (2002) 3.95
Gene expression and the myth of the average cell. Trends Cell Biol (2003) 3.78
Real-time observation of transcription initiation and elongation on an endogenous yeast gene. Science (2011) 3.67
Fluorescence in situ hybridization: past, present and future. J Cell Sci (2003) 3.20
The great escape: when cancer cells hijack the genes for chemotaxis and motility. Annu Rev Cell Dev Biol (2005) 2.97
Single-molecule mRNA decay measurements reveal promoter- regulated mRNA stability in yeast. Cell (2011) 2.92
Visualization of single molecules of mRNA in situ. Methods Enzymol (2003) 2.62
A direct role for FMRP in activity-dependent dendritic mRNA transport links filopodial-spine morphogenesis to fragile X syndrome. Dev Cell (2008) 2.51
How and why does beta-actin mRNA target? Biol Cell (2005) 2.38
Dynamic sorting of nuclear components into distinct nucleolar caps during transcriptional inhibition. Mol Biol Cell (2005) 2.36
Activity-dependent trafficking and dynamic localization of zipcode binding protein 1 and beta-actin mRNA in dendrites and spines of hippocampal neurons. J Neurosci (2003) 2.34
Active transport of the survival motor neuron protein and the role of exon-7 in cytoplasmic localization. J Neurosci (2003) 2.28
A transgenic mouse for in vivo detection of endogenous labeled mRNA. Nat Methods (2011) 2.27
The dynamics of mammalian P body transport, assembly, and disassembly in vivo. Mol Biol Cell (2008) 2.25
Single β-actin mRNA detection in neurons reveals a mechanism for regulating its translatability. Science (2014) 2.23
Two ZBP1 KH domains facilitate beta-actin mRNA localization, granule formation, and cytoskeletal attachment. J Cell Biol (2002) 2.20
Visualization of dynamics of single endogenous mRNA labeled in live mouse. Science (2014) 2.20
In vivo imaging of labelled endogenous β-actin mRNA during nucleocytoplasmic transport. Nature (2010) 2.16
Stepwise RNP assembly at the site of H/ACA RNA transcription in human cells. J Cell Biol (2006) 2.09
Asymmetric sorting of ash1p in yeast results from inhibition of translation by localization elements in the mRNA. Mol Cell (2002) 2.08
A new yeast PUF family protein, Puf6p, represses ASH1 mRNA translation and is required for its localization. Genes Dev (2004) 2.05
Real-time visualization of ZBP1 association with beta-actin mRNA during transcription and localization. Curr Biol (2003) 2.04
Visualization of mRNA translation in living cells. J Cell Biol (2006) 2.03
Localization of all seven messenger RNAs for the actin-polymerization nucleator Arp2/3 complex in the protrusions of fibroblasts. J Cell Sci (2005) 1.95
Imaging sites of N-wasp activity in lamellipodia and invadopodia of carcinoma cells. Curr Biol (2004) 1.91
ZBP1 regulates mRNA stability during cellular stress. J Cell Biol (2006) 1.84
Multiprotein complexes of the survival of motor neuron protein SMN with Gemins traffic to neuronal processes and growth cones of motor neurons. J Neurosci (2006) 1.80
Transcription of functionally related constitutive genes is not coordinated. Nat Struct Mol Biol (2010) 1.78
A predominantly nuclear protein affecting cytoplasmic localization of beta-actin mRNA in fibroblasts and neurons. J Cell Biol (2002) 1.77
Imaging transcription in living cells. Annu Rev Biophys (2009) 1.76
Localization of a beta-actin messenger ribonucleoprotein complex with zipcode-binding protein modulates the density of dendritic filopodia and filopodial synapses. J Neurosci (2003) 1.74
Structural basis for the coevolution of a viral RNA-protein complex. Nat Struct Mol Biol (2007) 1.71
A single molecule view of gene expression. Trends Cell Biol (2009) 1.69
The PTB interacting protein raver1 regulates alpha-tropomyosin alternative splicing. EMBO J (2003) 1.68
Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs): post-transcriptional drivers of cancer progression? Cell Mol Life Sci (2012) 1.68
Pathways for mRNA localization in the cytoplasm. Trends Biochem Sci (2006) 1.66
Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs. RNA (2008) 1.63
Nuclear export dynamics of RNA-protein complexes. Nature (2011) 1.63
Variegated gene expression caused by cell-specific long-range DNA interactions. Nat Cell Biol (2011) 1.63
ZBP1 recognition of beta-actin zipcode induces RNA looping. Genes Dev (2010) 1.63
Single-molecule analysis of gene expression using two-color RNA labeling in live yeast. Nat Methods (2012) 1.62
Interactions of elongation factor 1alpha with F-actin and beta-actin mRNA: implications for anchoring mRNA in cell protrusions. Mol Biol Cell (2002) 1.60
Eukaryotic transcriptional dynamics: from single molecules to cell populations. Nat Rev Genet (2013) 1.57
Modern fluorescent proteins and imaging technologies to study gene expression, nuclear localization, and dynamics. Curr Opin Cell Biol (2011) 1.55
A peptide motif in Raver1 mediates splicing repression by interaction with the PTB RRM2 domain. Nat Struct Mol Biol (2006) 1.52
Translation of ASH1 mRNA is repressed by Puf6p-Fun12p/eIF5B interaction and released by CK2 phosphorylation. Genes Dev (2008) 1.50
Activation of oligodendroglial Fyn kinase enhances translation of mRNAs transported in hnRNP A2-dependent RNA granules. J Cell Biol (2008) 1.44
Metabolic cycling in single yeast cells from unsynchronized steady-state populations limited on glucose or phosphate. Proc Natl Acad Sci U S A (2010) 1.44
Gene expression profiling in single cells within tissue. Nat Methods (2005) 1.43
YRA1 autoregulation requires nuclear export and cytoplasmic Edc3p-mediated degradation of its pre-mRNA. Mol Cell (2007) 1.43
RNA localization. J Cell Sci (2005) 1.39
Imaging gene expression in single living cells. Nat Rev Mol Cell Biol (2004) 1.39
Fluorescence fluctuation spectroscopy enables quantitative imaging of single mRNAs in living cells. Biophys J (2012) 1.37
She2p is a novel RNA binding protein with a basic helical hairpin motif. Cell (2004) 1.37
ZBP2 facilitates binding of ZBP1 to beta-actin mRNA during transcription. Mol Cell Biol (2007) 1.35
Dynamics of transcription and mRNA export. Curr Opin Cell Biol (2005) 1.35
The life of an mRNA in space and time. J Cell Sci (2010) 1.31
Mechanisms and cellular roles of local protein synthesis in mammalian cells. Curr Opin Cell Biol (2008) 1.31
Spatial arrangement of an RNA zipcode identifies mRNAs under post-transcriptional control. Genes Dev (2012) 1.26
The survival of motor neuron (SMN) protein interacts with the mRNA-binding protein HuD and regulates localization of poly(A) mRNA in primary motor neuron axons. J Neurosci (2011) 1.25
Promotion of importin alpha-mediated nuclear import by the phosphorylation-dependent binding of cargo protein to 14-3-3. J Cell Biol (2005) 1.23
Colocalization of different influenza viral RNA segments in the cytoplasm before viral budding as shown by single-molecule sensitivity FISH analysis. PLoS Pathog (2013) 1.23
Maturation of mammalian H/ACA box snoRNAs: PAPD5-dependent adenylation and PARN-dependent trimming. RNA (2012) 1.22
RNA processing and export. Cold Spring Harb Perspect Biol (2010) 1.22
Measurement of barbed ends, actin polymerization, and motility in live carcinoma cells after growth factor stimulation. Cell Motil Cytoskeleton (2004) 1.21
The nuclear connection in RNA transport and localization. Trends Cell Biol (2002) 1.20
Nuclear pore component Nup98 is a potential tumor suppressor and regulates posttranscriptional expression of select p53 target genes. Mol Cell (2012) 1.19
Temporal and spatial characterization of nonsense-mediated mRNA decay. Genes Dev (2013) 1.18
Stable morphology, but dynamic internal reorganisation, of interphase human chromosomes in living cells. PLoS One (2010) 1.17
Imaging mRNA movement from transcription sites to translation sites. Semin Cell Dev Biol (2007) 1.17
The armadillo protein p0071 regulates Rho signalling during cytokinesis. Nat Cell Biol (2006) 1.16
Developmental timing in Dictyostelium is regulated by the Set1 histone methyltransferase. Dev Biol (2006) 1.15
Single-mRNA counting using fluorescent in situ hybridization in budding yeast. Nat Protoc (2012) 1.15
Keratins mediate localization of hemidesmosomes and repress cell motility. J Invest Dermatol (2012) 1.15
β-Actin mRNA compartmentalization enhances focal adhesion stability and directs cell migration. Genes Dev (2012) 1.13
ZBP1 enhances cell polarity and reduces chemotaxis. J Cell Sci (2007) 1.11