Published in Proc Natl Acad Sci U S A on October 01, 1976
Lack of correlation between tumorigenicity and level of plasminogen activator in fibroblasts transformed by Rous sarcoma virus. Proc Natl Acad Sci U S A (1978) 0.92
Thromboplastic and fibrinolytic activities of cultured human cancer cell lines. Br J Cancer (1979) 0.90
Distinct transformation phenotypes induced by polyoma virus and simian virus 40 in rat fibroblasts and their control by an early viral gene function. J Virol (1980) 0.86
Protease effects on specific growth properties of normal and transformed baby hamster kidney cells. Proc Natl Acad Sci U S A (1977) 0.80
Modulation of the plasminogen activator activity of a transformed cell line by cell density. Mol Cell Biol (1982) 0.77
Tumorigenicity of herpesvirus-transformed cells correlates with production of plasminogen activator. Mol Cell Biol (1981) 0.75
Modulation of cell-associated plasminogen activator activity by cocultivation of a stem cell and its tumorigenic descendant. Mol Cell Biol (1984) 0.75
Protein measurement with the Folin phenol reagent. J Biol Chem (1951) 1743.91
Plasminogen: purification from human plasma by affinity chromatography. Science (1970) 11.72
The effects of reciprocal changes in temperature on the transformed state of cells infected with a rous sarcoma virus mutant. Virology (1971) 7.83
Alteration of cell-surface proteins by viral transformation and by proteolysis. Proc Natl Acad Sci U S A (1973) 6.98
Cellular tumorigenicity in nude mice: correlation with cell growth in semi-solid medium. Cell (1974) 6.18
A difference in the architecture of the surface membrane of normal and virally transformed cells. Proc Natl Acad Sci U S A (1969) 6.03
Rous sarcoma virus: a function required for the maintenance of the transformed state. Nature (1970) 5.66
An enzymatic function associated with transformation of fibroblasts by oncogenic viruses. I. Chick embryo fibroblast cultures transformed by avian RNA tumor viruses. J Exp Med (1973) 5.53
The polymerization of proteins; the action of thrombin on fibrinogen. Arch Biochem Biophys (1951) 5.46
Purification of DNA complementary to nucleotide sequences required for neoplastic transformation of fibroblasts by avian sarcoma viruses. J Mol Biol (1976) 5.07
An enzymatic function associated with transformation of fibroblasts by oncogenic viruses. II. Mammalian fibroblast cultures transformed by DNA and RNA tumor viruses. J Exp Med (1973) 4.99
Differences between the ribonucleic acids of transforming and nontransforming avian tumor viruses. Proc Natl Acad Sci U S A (1970) 4.91
Tumor viruses: 1974. Cold Spring Harb Symp Quant Biol (1975) 4.44
Proteolytic enzymes initiating cell division and escape from contact inhibition of growth. Nature (1970) 3.84
Release from density dependent growth inhibition by proteolytic enzymes. Nature (1970) 3.20
Analysis of a functional change in membrane in the process of cell transformation by Rous sarcoma virus; alteration in the characteristics of sugar transport. Virology (1970) 2.94
Fibrinolysis associated with oncogenic transformation. Partial purification and characterization of the cell factor, a plasminogen activator. J Biol Chem (1974) 2.89
Temperature-dependent alterations in sugar transport in cells infected by a temperature-sensitive mutant of Rous sarcoma virus. Proc Natl Acad Sci U S A (1971) 2.83
Plasminogen activator production accompanies loss of anchorage regulation in transformation of primary rat embryo cells by simian virus 40. Proc Natl Acad Sci U S A (1974) 2.59
Increased protease levels in transformed cells: a casein overlay assay for the detection of plasminogen activator production. Cell (1974) 2.31
Selective inhibition of growth of transformed cells by protease inhibitors. Proc Natl Acad Sci U S A (1972) 1.57
Fibrinolytic activity in a human fibrosarcoma cell line and evidence for the induction of plasminogen activator secretion during tumor formation. Cell (1975) 1.48
Induction of mutations in an RNA tumour virus by an analogue of a DNA precursor. Nat New Biol (1971) 1.46
Plasminogen, the serum proenzyme activated by factors from cells transformed by oncogenic viruses. J Biol Chem (1974) 1.43
Plasminogen-independent fibrinolysis by proteases produced by transformed chick embryo fibroblasts. Proc Natl Acad Sci U S A (1975) 1.32
Conditional lethal mutants of avian sarcoma viruses. I. Physiology of ts 75 and ts 149. Virology (1971) 1.28
Effects of protease inhibitors on growth of hamster tumor cells in culture. Cancer Res (1972) 1.20
[Isolation and study of a conditional mutant of Rous virus with thermosensitive transforming capacity]. C R Acad Sci Hebd Seances Acad Sci D (1970) 1.14
Non-selective inhibition of transformed cell growth by a protease inhibitor. Proc Natl Acad Sci U S A (1974) 0.96
Inhibition of protease activity in cultures of rous sarcoma virus-transformed cells: effect on the transformed phenotype. Cell (1975) 0.96
Involvement of cell and serum proteases in exposing tumor-specific agglutinin sites. Ann N Y Acad Sci (1974) 0.81
Identification of a tumor-specific determinant on neoplastic cell surfaces. Proc Natl Acad Sci U S A (1967) 5.63
New mutations in the S cistron of bacteriophage lambda affecting host cell lysis. Virology (1969) 4.78
Evidence that the src gene product of Rous sarcoma virus is membrane associated. Virology (1980) 3.71
Ethylene glycol poisoning: toxicokinetic and analytical factors affecting laboratory diagnosis. Clin Chem (1998) 3.32
Changes in microfilament organization and surface topogrophy upon transformation of chick embryo fibroblasts with Rous sarcoma virus. Proc Natl Acad Sci U S A (1976) 2.38
Only membrane-associated RSV src proteins have amino-terminally bound lipid. Nature (1983) 2.37
Increased protease levels in transformed cells: a casein overlay assay for the detection of plasminogen activator production. Cell (1974) 2.31
Changes in amino-terminal sequences of pp60src lead to decreased membrane association and decreased in vivo tumorigenicity. Cell (1982) 2.13
In vitro phosphorylation of angiotensin analogs by tyrosyl protein kinases. J Biol Chem (1983) 2.10
Proteolytic cleavage by plasmin of the HA polypeptide of influenza virus: host cell activation of serum plasminogen. Virology (1973) 2.01
Subcellular localization of pp60src in RSV-transformed cells. Curr Top Microbiol Immunol (1983) 1.93
Differences in intracellular location of pp60src in rat and chicken cells transformed by Rous sarcoma virus. Proc Natl Acad Sci U S A (1980) 1.91
Intracellular Ca2+ mobilization by arachidonic acid. Comparison with myo-inositol 1,4,5-trisphosphate in isolated pancreatic islets. J Biol Chem (1986) 1.70
Temperature-sensitive membrane association of pp60src in tsNY68-infected cells correlates with increased tyrosine phosphorylation of membrane-associated proteins. Virology (1983) 1.58
Binding of deoxyribonuclease I to actin: a new way to visualize microfilament bundles in nonmuscle cells. J Histochem Cytochem (1978) 1.50
Synthetic peptide fragment of src gene product inhibits the src protein kinase and crossreacts immunologically with avian onc kinases and cellular phosphoproteins. Proc Natl Acad Sci U S A (1981) 1.39
Aortic valve injury secondary to blunt trauma from an air bag. Tenn Med (1997) 1.37
Novel localization of pp60src in Rous sarcoma virus-transformed rat and goat cells and in chicken cells transformed by viruses rescued from these mammalian cells. Virology (1982) 1.35
Tyrosyl protein kinases in normal rat liver: identification and partial characterization. Proc Natl Acad Sci U S A (1983) 1.35
Size-variant pp60src proteins of recovered avian sarcoma viruses interact with adhesion plaques as peripheral membrane proteins: effects on cell transformation. Mol Cell Biol (1984) 1.34
Nitric oxide and cyclic GMP formation induced by interleukin 1 beta in islets of Langerhans. Evidence for an effector role of nitric oxide in islet dysfunction. Biochem J (1992) 1.34
Studies on termination of in vitro ribonucleic acid synthesis by rho factor. J Biol Chem (1972) 1.29
Glucose-induced accumulation of inositol trisphosphates in isolated pancreatic islets. Predominance of the 1,3,4-isomer. Biochem J (1986) 1.25
Synaptotagmin III/VII isoforms mediate Ca2+-induced insulin secretion in pancreatic islet beta -cells. J Biol Chem (2000) 1.24
Interleukin 1 is potent modulator of insulin secretion from isolated rat islets of Langerhans. Diabetes (1987) 1.23
Acute aspirin overdose: mechanisms of toxicity. Ther Drug Monit (1992) 1.22
Virus- and cell-encoded tyrosine protein kinases inactivate DNA topoisomerases in vitro. Nature (1985) 1.16
The digitonin-permeabilized pancreatic islet model. Effect of myo-inositol 1,4,5-trisphosphate on Ca2+ mobilization. Biochem J (1985) 1.13
Glucose regulation of glutaminolysis and its role in insulin secretion. Diabetes (1999) 1.08
The role of sialic acid in the release of proteins from L1210 leukemia cells. Cancer Res (1966) 1.07
The heterotrimeric G-protein Gi is localized to the insulin secretory granules of beta-cells and is involved in insulin exocytosis. J Biol Chem (1995) 1.06
Phosphorylation of synthetic peptides containing Tyr-Met-X-Met motifs by nonreceptor tyrosine kinases in vitro. J Biol Chem (1993) 1.04
Expression of insulin receptor mRNA and insulin receptor substrate 1 in pancreatic islet beta-cells. Diabetes (1996) 1.01
Glucose 6-phosphate regulates Ca2+ steady state in endoplasmic reticulum of islets. A possible link in glucose-induced insulin secretion. J Biol Chem (1986) 1.00
Protein phosphorylation in permeabilized pancreatic islet cells. Biochem J (1985) 0.98
Glucose-induced insulin receptor tyrosine phosphorylation in insulin-secreting beta-cells. Diabetes (1995) 0.98
Inhibition of phospholipase A2 and insulin secretion in pancreatic islets. Biochim Biophys Acta (1992) 0.97
Descriptive and mechanistic considerations of interleukin 1 and insulin secretion. Diabetes (1988) 0.97
Targeting the PML/RAR alpha translocation product triggers apoptosis in promyelocytic leukemia cells. Oncogene (1998) 0.97
Effects of the src gene product on microfilament and microtubule organization in avian and mammalian cells infected with the same temperature-sensitive mutant of Rous sarcoma virus. Virology (1979) 0.97
GTP mobilization of Ca2+ from the endoplasmic reticulum of islets. Comparison with myo-inositol 1,4,5-trisphosphate. Biochem J (1987) 0.96
Reduced synthesis of pp60src and expression of the transformation-related phenotype in interferon-treated Rous sarcoma virus-transformed rat cells. Mol Cell Biol (1983) 0.96
Glucose-induced phospholipid hydrolysis in isolated pancreatic islets: quantitative effects on the phospholipid content of arachidonate and other fatty acids. Biochim Biophys Acta (1986) 0.94
The role of phospholipid-derived mediators including arachidonic acid, its metabolites, and inositoltrisphosphate and of intracellular Ca2+ in glucose-induced insulin secretion by pancreatic islets. Prog Lipid Res (1987) 0.92
Comparison of effects of phorbol esters and glucose on protein kinase C activation and insulin secretion in pancreatic islets. Biochem J (1989) 0.92
Lack of correlation between tumorigenicity and level of plasminogen activator in fibroblasts transformed by Rous sarcoma virus. Proc Natl Acad Sci U S A (1978) 0.92
Purification and characterization of the major species of tyrosine protein kinase in rat liver. J Biol Chem (1984) 0.90
Diacylglycerol hydrolysis to arachidonic acid is necessary for insulin secretion from isolated pancreatic islets: sequential actions of diacylglycerol and monoacylglycerol lipases. Biochemistry (1994) 0.90
Short oligonucleotides as external guide sequences for site-specific cleavage of RNA molecules with human RNase P. RNA (1998) 0.90
Localization and characterization of the src-gene product of Rous sarcoma virus. Cold Spring Harb Symp Quant Biol (1980) 0.90
Regulation of amyloid precursor protein secretion by glutamate receptors in human Ntera 2 neurons. J Biol Chem (1998) 0.89
A frontal variant of Alzheimer's disease exhibits decreased calcium-independent phospholipase A2 activity in the prefrontal cortex. Neurochem Int (2000) 0.89
Phorbol ester action is independent of viral and cellular src kinase levels. Science (1980) 0.88
Parallel effects of arachidonic acid on insulin secretion, calmodulin-dependent protein kinase activity and protein kinase C activity in pancreatic islets. Cell Calcium (1992) 0.86
Arachidonic acid metabolism and insulin secretion by isolated human pancreatic islets. Diabetes (1988) 0.86
Inhibition of leukocyte chemotaxis by Glu-Glu-Glu-Glu-Tyr-Pro-Met-Glu and Leu-Ile-Glu-Asp-Asn-Glu-Tyr-Thr-Ala-Arg-Gln-Gly. Biochem Biophys Res Commun (1984) 0.86
Activation of the sphingomyelinase/ceramide signal transduction pathway in insulin-secreting beta-cells: role in cytokine-induced beta-cell death. Diabetes (1999) 0.86
Regulation of amyloid precursor protein (APP) secretion by protein kinase calpha in human ntera 2 neurons (NT2N). Biochemistry (2000) 0.85
Nuclease-resistant external guide sequence-induced cleavage of target RNA by human ribonuclease P. Antisense Nucleic Acid Drug Dev (1998) 0.85
Interleukin-1beta stimulation of c-Jun NH(2)-terminal kinase activity in insulin-secreting cells: evidence for cytoplasmic restriction. Diabetes (2001) 0.85
Carbachol stimulation of phospholipase A2 and insulin secretion in pancreatic islets. Biochem J (1992) 0.84
Arachidonic acid metabolism in isolated pancreatic islets. IV. Negative ion-mass spectrometric quantitation of monooxygenase product synthesis by liver and islets. Biochim Biophys Acta (1985) 0.84
Serum lactate and lactate dehydrogenase in high concentrations interfere in enzymatic assay of ethylene glycol. Clin Chem (1996) 0.84
Insulin regulation of beta-cell function involves a feedback loop on SERCA gene expression, Ca(2+) homeostasis, and insulin expression and secretion. Biochemistry (2000) 0.83
Interleukin 1-induced prostaglandin E2 accumulation by isolated pancreatic islets. Diabetes (1989) 0.82
The "hook effect": high concentrations of prostate-specific antigen giving artifactually low values on one-step immunoassay. N Engl J Med (1989) 0.82
Wortmannin inhibits insulin secretion in pancreatic islets and beta-TC3 cells independent of its inhibition of phosphatidylinositol 3-kinase. Diabetes (1996) 0.82
Insulin receptor substrate 1-induced inhibition of endoplasmic reticulum Ca2+ uptake in beta-cells. Autocrine regulation of intracellular ca2+ homeostasis and insulin secretion. J Biol Chem (1999) 0.82
On the action of fluorouracil on leukemia cells. Cancer Res (1966) 0.81
G-protein specificity in signaling pathways that mobilize calcium in insulin-secreting beta-TC3 cells. Diabetes (1993) 0.81
Involvement of cell and serum proteases in exposing tumor-specific agglutinin sites. Ann N Y Acad Sci (1974) 0.81
Purification of recombinant pp60v-src protein tyrosine kinase and phosphorylation of peptides with different secondary structure preference. Biochemistry (1989) 0.81
Extremely high values of prostate-specific antigen in patients with adenocarcinoma of the prostate; demonstration of the "hook effect". Clin Chem (1988) 0.81
Protein kinase C regulation of intracellular and cell surface amyloid precursor protein (APP) cleavage in CHO695 cells. Biochemistry (2000) 0.81
Retinoic acid induction of calcium channel expression in human NT2N neurons. Biochem Biophys Res Commun (1998) 0.80
Arachidonic acid metabolism in isolated pancreatic islets. V. The enantiomeric composition of 12-hydroxy-5,8,10,14-eicosatetraenoic acid indicates synthesis by a 12-lipoxygenase rather than a monooxygenase. Biochim Biophys Acta (1989) 0.80
Cell mitotic cycle synthesis of NIL hamster glycolipids including the Forssman antigen. J Cell Biol (1974) 0.80
Inhibition of L1210 tumor growth by thymus DNA. Science (1965) 0.80
Mechanisms of spontaneous cytosolic Ca2+ transients in differentiated human neuronal cells. Eur J Neurosci (1998) 0.79
Quantitation of the fatty acid composition of phosphatidic acid by capillary gas chromatography electron-capture detection with picomole sensitivity. J Chromatogr B Biomed Appl (1994) 0.79
Teratological assessment of five oxidative hair dyes in the rat. Toxicol Appl Pharmacol (1985) 0.79
Identification of phosphatidylinositol 3,4,5-trisphosphate in pancreatic islets and insulin-secreting beta-cells. Biochem Biophys Res Commun (1995) 0.79
1,5-Anhydroglucitol: a novel serum marker for screening and monitoring diabetes mellitus? Clin Chem (1994) 0.79
Calmodulin inhibits inositol trisphosphate-induced Ca2+ mobilization from the endoplasmic reticulum of islets. Biochem Biophys Res Commun (1986) 0.78
Identification of calcium-dependent phospholipase A2 isoforms in human and rat pancreatic islets and insulin secreting beta-cell lines. Endocrinology (1996) 0.78
Kinetics and mechanism of angiotensin phosphorylation by the transforming gene product of Rous sarcoma virus. J Biol Chem (1984) 0.78
Glucose-induced tyrosine phosphorylation of p125 in beta cells and pancreatic islets. A novel proximal signal in insulin secretion. J Biol Chem (1996) 0.78
Effects of temperature reduction on multiple sclerosis. Phys Ther (1970) 0.78
Benign dermal cylindroma of the external auditory canal: a clinicopathological report. Am J Otolaryngol (1985) 0.77
U-73122 does not specifically inhibit phospholipase C in rat pancreatic islets and insulin-secreting beta-cell lines. Life Sci (1994) 0.77
Transient activation of calcium-dependent phospholipase A2 by insulin secretagogues in isolated pancreatic islets. Biochemistry (1993) 0.77
Nighttime dosing assures postdistribution sampling for therapeutic drug monitoring of digoxin. Clin Chem (1996) 0.77
Phospholipase pathway in Alzheimer's disease brains: decrease in Galphai in dorsolateral prefrontal cortex. Brain Res Mol Brain Res (1999) 0.77
Delivery of oligoribonucleotides to human hepatoma cells using cationic lipid particles conjugated to ferric protoporphyrin IX (heme). Antisense Nucleic Acid Drug Dev (1997) 0.77
Eicosapentaenoic acid (C20:5) augments glucose-induced insulin secretion from beta-TC3 insulinoma cells. Pancreas (1996) 0.77
A ribozyme which discriminates in vitro between PML/RAR alpha, the t(15;17)-associated fusion RNA of acute promyelocytic leukemia, and PML and RAR alpha, the transcripts from the nonrearranged alleles. Cancer Res (1994) 0.76
The expression of plasminogen activator in Rous sarcoma virus-transformed cells is controlled both by the virus and the cell. Virology (1978) 0.76
Fuel secretagogue stimulation of arachidonic acid accumulation in fresh and cultured pancreatic islets. Mol Cell Endocrinol (1993) 0.76