Encapsulating a single G-quadruplex aptamer in a protein nanocavity.

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Interactions of the human telomere sequence with the nanocavity of the α-hemolysin ion channel reveal structure-dependent electrical signatures for hybrid folds. J Am Chem Soc (2013) 1.29

Single-molecule detection of folding and unfolding of the G-quadruplex aptamer in a nanopore nanocavity. Nucleic Acids Res (2008) 1.22

Solid-State and Biological Nanopore for Real-Time Sensing of Single Chemical and Sequencing of DNA. Nano Today (2013) 1.13

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Sampling a biomarker of the human immunodeficiency virus across a synthetic nanopore. ACS Nano (2013) 0.96

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Nanopore-based conformational analysis of a viral RNA drug target. ACS Nano (2014) 0.87

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Watching single proteins using engineered nanopores. Protein Pept Lett (2014) 0.80

Unfolding Kinetics of the Human Telomere i-Motif Under a 10 pN Force Imposed by the α-Hemolysin Nanopore Identify Transient Folded-State Lifetimes at Physiological pH. J Am Chem Soc (2015) 0.79

Nanopore sensing of botulinum toxin type B by discriminating an enzymatically cleaved Peptide from a synaptic protein synaptobrevin 2 derivative. ACS Appl Mater Interfaces (2014) 0.78

Mimicking Ribosomal Unfolding of RNA Pseudoknot in a Protein Channel. J Am Chem Soc (2015) 0.76

Unzipping of A-Form DNA-RNA, A-Form DNA-PNA, and B-Form DNA-DNA in the α-Hemolysin Nanopore. Biophys J (2016) 0.75

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Stochastic sensors inspired by biology. Nature (2001) 5.26

Sequence-specific detection of individual DNA strands using engineered nanopores. Nat Biotechnol (2001) 5.14

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Telomere maintenance as a target for anticancer drug discovery. Nat Rev Drug Discov (2002) 3.32

Unzipping kinetics of double-stranded DNA in a nanopore. Phys Rev Lett (2003) 3.32

Nanopore unzipping of individual DNA hairpin molecules. Biophys J (2004) 3.25

Detecting protein analytes that modulate transmembrane movement of a polymer chain within a single protein pore. Nat Biotechnol (2000) 3.11

Single-molecule analysis of DNA-protein complexes using nanopores. Nat Methods (2007) 2.99

Recognizing a single base in an individual DNA strand: a step toward DNA sequencing in nanopores. Angew Chem Int Ed Engl (2005) 2.83

Studies on the structure and dynamics of the human telomeric G quadruplex by single-molecule fluorescence resonance energy transfer. Proc Natl Acad Sci U S A (2003) 2.82

Toward single molecule DNA sequencing: direct identification of ribonucleoside and deoxyribonucleoside 5'-monophosphates by using an engineered protein nanopore equipped with a molecular adapter. J Am Chem Soc (2006) 2.68

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A nanosensor for transmembrane capture and identification of single nucleic Acid molecules. Biophys J (2004) 2.27

Natural and engineered nucleic acids as tools to explore biology. Nature (2004) 2.26

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Molecular beacons for detecting DNA binding proteins. Nat Biotechnol (2002) 1.87

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Capture of a single molecule in a nanocavity. Science (2001) 1.81

Reversal of charge selectivity in transmembrane protein pores by using noncovalent molecular adapters. Proc Natl Acad Sci U S A (2000) 1.79

DNA duplex-quadruplex exchange as the basis for a nanomolecular machine. Proc Natl Acad Sci U S A (2003) 1.79

Stochastic sensing of nanomolar inositol 1,4,5-trisphosphate with an engineered pore. Chem Biol (2002) 1.69

Supramolecular architectures generated by self-assembly of guanosine derivatives. Chem Soc Rev (2006) 1.66

Multi-nanopore force spectroscopy for DNA analysis. Biophys J (2006) 1.63

Electroosmotic enhancement of the binding of a neutral molecule to a transmembrane pore. Proc Natl Acad Sci U S A (2003) 1.62

Single DNA rotaxanes of a transmembrane pore protein. Angew Chem Int Ed Engl (2004) 1.48

G-Quadruplex DNA as a target for drug design. Curr Pharm Des (2000) 1.45

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Functional and dysfunctional roles of quadruplex DNA in cells. Chem Biol (2001) 1.43

Folding of the thrombin aptamer into a G-quadruplex with Sr(2+): stability, heat, and hydration. J Am Chem Soc (2001) 1.32

Probing distance and electrical potential within a protein pore with tethered DNA. Biophys J (2002) 1.29

A storable encapsulated bilayer chip containing a single protein nanopore. J Am Chem Soc (2007) 1.28

Determining the folding and unfolding rate constants of nucleic acids by biosensor. Application to telomere G-quadruplex. J Am Chem Soc (2004) 1.25

Ion selective folding of loop domains in a potent anti-HIV oligonucleotide. Biochemistry (1997) 1.23

Optical sensors based on hybrid aptamer/conjugated polymer complexes. J Am Chem Soc (2004) 1.22

Structures of the potassium-saturated, 2:1, and intermediate, 1:1, forms of a quadruplex DNA. Nucleic Acids Res (2000) 1.20

Temperature-responsive protein pores. J Am Chem Soc (2006) 1.10

Single-molecule covalent chemistry with spatially separated reactants. Angew Chem Int Ed Engl (2003) 1.08

G-quadruplex formation of thrombin-binding aptamer detected by electrospray ionization mass spectrometry. J Am Chem Soc (2003) 1.06

The internal cavity of the staphylococcal alpha-hemolysin pore accommodates approximately 175 exogenous amino acid residues. Biochemistry (2005) 1.01

Protein-protein interaction studies based on molecular aptamers by affinity capillary electrophoresis. Anal Chem (2004) 0.99

Photoisomerization of an individual azobenzene molecule in water: an on-off switch triggered by light at a fixed wavelength. J Am Chem Soc (2006) 0.93

Stochastic sensing on a modular chip containing a single-ion channel. Anal Chem (2007) 0.93

The thrombin binding aptamer GGTTGGTGTGGTTGG forms a bimolecular guanine tetraplex. Biochem Biophys Res Commun (2006) 0.93

In vitro synthesis, tetramerization and single channel characterization of virus-encoded potassium channel Kcv. FEBS Lett (2007) 0.93

Ethanol is a better inducer of DNA guanine tetraplexes than potassium cations. Biopolymers (2006) 0.92

Tertiary structure motif of Oxytricha telomere DNA. Biochemistry (1994) 0.85

Single-molecule observation of the catalytic subunit of cAMP-dependent protein kinase binding to an inhibitor peptide. Chem Biol (2005) 1.74

Plasma microRNAs as novel biomarkers for early detection of lung cancer. Int J Clin Exp Pathol (2011) 1.73

Nanopore-based detection of circulating microRNAs in lung cancer patients. Nat Nanotechnol (2011) 1.68

Molecular bases of cyclodextrin adapter interactions with engineered protein nanopores. Proc Natl Acad Sci U S A (2010) 1.41

Single protein pores containing molecular adapters at high temperatures. Angew Chem Int Ed Engl (2005) 1.39

Capturing single molecules of immunoglobulin and ricin with an aptamer-encoded glass nanopore. Anal Chem (2009) 1.38

Single-molecule detection of folding and unfolding of the G-quadruplex aptamer in a nanopore nanocavity. Nucleic Acids Res (2008) 1.22

p53-induced gene 3 mediates cell death induced by glutathione peroxidase 3. J Biol Chem (2012) 1.13

Stochastic sensing of TNT with a genetically engineered pore. Chembiochem (2005) 0.98

Method of creating a nanopore-terminated probe for single-molecule enantiomer discrimination. Anal Chem (2009) 0.95

In vitro synthesis, tetramerization and single channel characterization of virus-encoded potassium channel Kcv. FEBS Lett (2007) 0.93

Carriers versus adapters in stochastic sensing. Chemphyschem (2005) 0.92

Programming nanopore ion flow for encoded multiplex microRNA detection. ACS Nano (2014) 0.89

Probing molecular pathways for DNA orientational trapping, unzipping and translocation in nanopores by using a tunable overhang sensor. Nanoscale (2014) 0.86

Apolipoprotein E polymorphism in normal Han Chinese population: frequency and effect on lipid parameters. Mol Biol Rep (2008) 0.85

Designing a polycationic probe for simultaneous enrichment and detection of microRNAs in a nanopore. ACS Nano (2013) 0.84

Single-molecule investigation of G-quadruplex using a nanopore sensor. Methods (2012) 0.83

Separation of heteromeric potassium channel Kcv towards probing subunit composition-regulated ion permeation and gating. FEBS Lett (2010) 0.79

Nanopore sensing of botulinum toxin type B by discriminating an enzymatically cleaved Peptide from a synaptic protein synaptobrevin 2 derivative. ACS Appl Mater Interfaces (2014) 0.78

When less is more in a nanopore. Nat Nanotechnol (2012) 0.78

Designing DNA interstrand lock for locus-specific methylation detection in a nanopore. Sci Rep (2013) 0.77

Tuning the tetraethylammonium sensitivity of potassium channel Kcv by subunit combination. J Gen Physiol (2012) 0.76

Remote activation of a nanopore for high performance genetic detection using a pH taxis-mimicking mechanism. Anal Chem (2017) 0.75

Nanolock-Nanopore Facilitated Digital Diagnostics of Cancer Driver Mutation in Tumor Tissue. ACS Sens (2017) 0.75

Corrigendum: Single Molecule Investigation of Ag+ Interactions with Single Cytosine-, Methylcytosine- and Hydroxymethylcytosine-Cytosine Mismatches in a Nanopore. Sci Rep (2015) 0.75

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Nanopore single-molecule dielectrophoretic detection of cancer-derived microRNA biomarkers. Conf Proc IEEE Eng Med Biol Soc (2013) 0.75

Two unusual cases of intractable hyperthyroidism responsive to octreotide: Munchausen syndrome or not? Clin Chim Acta (2011) 0.75