Published in Chem Biol on July 01, 2002
Continuous base identification for single-molecule nanopore DNA sequencing. Nat Nanotechnol (2009) 8.09
Recognizing a single base in an individual DNA strand: a step toward DNA sequencing in nanopores. Angew Chem Int Ed Engl (2005) 2.83
Connexin channel permeability to cytoplasmic molecules. Prog Biophys Mol Biol (2007) 2.73
Enhanced translocation of single DNA molecules through alpha-hemolysin nanopores by manipulation of internal charge. Proc Natl Acad Sci U S A (2008) 2.11
Interactions of peptides with a protein pore. Biophys J (2005) 1.79
Applications of biological pores in nanomedicine, sensing, and nanoelectronics. Curr Opin Biotechnol (2010) 1.66
Protein detection by nanopores equipped with aptamers. J Am Chem Soc (2012) 1.55
Nucleobase recognition in ssDNA at the central constriction of the alpha-hemolysin pore. Nano Lett (2010) 1.51
Controlled translocation of individual DNA molecules through protein nanopores with engineered molecular brakes. Nano Lett (2011) 1.42
HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis. Nature (2016) 1.39
Analysis of single nucleic acid molecules with protein nanopores. Methods Enzymol (2010) 1.29
Single-molecule detection of folding and unfolding of the G-quadruplex aptamer in a nanopore nanocavity. Nucleic Acids Res (2008) 1.22
Mechanism of KCl enhancement in detection of nonionic polymers by nanopore sensors. Biophys J (2008) 1.14
Solid-State and Biological Nanopore for Real-Time Sensing of Single Chemical and Sequencing of DNA. Nano Today (2013) 1.13
Single molecule sensing by nanopores and nanopore devices. Analyst (2009) 1.09
Nanopore-based fourth-generation DNA sequencing technology. Genomics Proteomics Bioinformatics (2015) 1.05
Nanopore-based identification of individual nucleotides for direct RNA sequencing. Nano Lett (2013) 1.04
Encapsulating a single G-quadruplex aptamer in a protein nanocavity. J Phys Chem B (2008) 0.98
Field-dependent effect of crown ether (18-crown-6) on ionic conductance of alpha-hemolysin channels. Biophys J (2004) 0.96
Translocation of single-stranded DNA through the α-hemolysin protein nanopore in acidic solutions. Electrophoresis (2011) 0.95
Robust properties of membrane-embedded connector channel of bacterial virus phi29 DNA packaging motor. Mol Biosyst (2010) 0.95
Stochastic sensing on a modular chip containing a single-ion channel. Anal Chem (2007) 0.93
Stochastic study of the effect of ionic strength on noncovalent interactions in protein pores. Biophys J (2007) 0.92
Orientation of the monomeric porin OmpG in planar lipid bilayers. Chembiochem (2008) 0.88
Resolved single-molecule detection of individual species within a mixture of anti-biotin antibodies using an engineered monomeric nanopore. ACS Nano (2015) 0.87
Single-molecule investigation of G-quadruplex using a nanopore sensor. Methods (2012) 0.83
DNA-functionalized silicon nitride nanopores for sequence-specific recognition of DNA biosensor. Nanoscale Res Lett (2015) 0.82
Stochastic detection of Pim protein kinases reveals electrostatically enhanced association of a peptide substrate. Proc Natl Acad Sci U S A (2013) 0.82
An engineered dimeric protein pore that spans adjacent lipid bilayers. Nat Commun (2013) 0.82
Nanopore detection of copper ions using a polyhistidine probe. Biosens Bioelectron (2013) 0.81
Obstructing toxin pathways by targeted pore blockage. Chem Rev (2012) 0.80
Channel-forming bacterial toxins in biosensing and macromolecule delivery. Toxins (Basel) (2014) 0.77
Chemical-induced pH-mediated molecular switch. Anal Chem (2011) 0.75
Single Nanoparticle Translocation Through Chemically Modified Solid Nanopore. Nanoscale Res Lett (2016) 0.75
Peptide-Mediated Nanopore Detection of Uranyl Ions in Aqueous Media. ACS Sens (2017) 0.75
The potential and challenges of nanopore sequencing. Nat Biotechnol (2008) 14.24
Continuous base identification for single-molecule nanopore DNA sequencing. Nat Nanotechnol (2009) 8.09
Single-nucleotide discrimination in immobilized DNA oligonucleotides with a biological nanopore. Proc Natl Acad Sci U S A (2009) 3.74
Recognizing a single base in an individual DNA strand: a step toward DNA sequencing in nanopores. Angew Chem Int Ed Engl (2005) 2.83
Toward single molecule DNA sequencing: direct identification of ribonucleoside and deoxyribonucleoside 5'-monophosphates by using an engineered protein nanopore equipped with a molecular adapter. J Am Chem Soc (2006) 2.68
Enhanced translocation of single DNA molecules through alpha-hemolysin nanopores by manipulation of internal charge. Proc Natl Acad Sci U S A (2008) 2.11
Identification of epigenetic DNA modifications with a protein nanopore. Chem Commun (Camb) (2010) 1.93
Functional bionetworks from nanoliter water droplets. J Am Chem Soc (2007) 1.81
Interactions of peptides with a protein pore. Biophys J (2005) 1.79
Formation of droplet networks that function in aqueous environments. Nat Nanotechnol (2011) 1.78
Direct transfer of membrane proteins from bacteria to planar bilayers for rapid screening by single-channel recording. Nat Chem Biol (2006) 1.77
Single-molecule observation of the catalytic subunit of cAMP-dependent protein kinase binding to an inhibitor peptide. Chem Biol (2005) 1.74
Subunit composition of a bicomponent toxin: staphylococcal leukocidin forms an octameric transmembrane pore. Protein Sci (2002) 1.73
A tissue-like printed material. Science (2013) 1.66
Hybrid pore formation by directed insertion of α-haemolysin into solid-state nanopores. Nat Nanotechnol (2010) 1.65
Electroosmotic enhancement of the binding of a neutral molecule to a transmembrane pore. Proc Natl Acad Sci U S A (2003) 1.62
Droplet networks with incorporated protein diodes show collective properties. Nat Nanotechnol (2009) 1.61
A primary hydrogen-deuterium isotope effect observed at the single-molecule level. Nat Chem (2010) 1.58
Protein detection by nanopores equipped with aptamers. J Am Chem Soc (2012) 1.55
Protein nanopores with covalently attached molecular adapters. J Am Chem Soc (2007) 1.55
Real-time stochastic detection of multiple neurotransmitters with a protein nanopore. ACS Nano (2012) 1.52
Nucleobase recognition in ssDNA at the central constriction of the alpha-hemolysin pore. Nano Lett (2010) 1.51
Outer membrane protein G: Engineering a quiet pore for biosensing. Proc Natl Acad Sci U S A (2008) 1.48
Single DNA rotaxanes of a transmembrane pore protein. Angew Chem Int Ed Engl (2004) 1.48
Partitioning of individual flexible polymers into a nanoscopic protein pore. Biophys J (2003) 1.45
Elimination of a bacterial pore-forming toxin by sequential endocytosis and exocytosis. FEBS Lett (2008) 1.44
Controlled translocation of individual DNA molecules through protein nanopores with engineered molecular brakes. Nano Lett (2011) 1.42
Molecular bases of cyclodextrin adapter interactions with engineered protein nanopores. Proc Natl Acad Sci U S A (2010) 1.41
Multiple base-recognition sites in a biological nanopore: two heads are better than one. Angew Chem Int Ed Engl (2010) 1.41
Asymmetric droplet interface bilayers. J Am Chem Soc (2008) 1.41
Single protein pores containing molecular adapters at high temperatures. Angew Chem Int Ed Engl (2005) 1.39
Screening blockers against a potassium channel with a droplet interface bilayer array. J Am Chem Soc (2008) 1.35
Membrane protein stoichiometry determined from the step-wise photobleaching of dye-labelled subunits. Chembiochem (2007) 1.33
Multistep protein unfolding during nanopore translocation. Nat Nanotechnol (2013) 1.29
Analysis of single nucleic acid molecules with protein nanopores. Methods Enzymol (2010) 1.29
Probing distance and electrical potential within a protein pore with tethered DNA. Biophys J (2002) 1.29
A storable encapsulated bilayer chip containing a single protein nanopore. J Am Chem Soc (2007) 1.28
Stochastic detection of motor protein-RNA complexes by single-channel current recording. Chemphyschem (2007) 1.24
Kinetics of a reversible covalent-bond-forming reaction observed at the single-molecule level. Angew Chem Int Ed Engl (2002) 1.21
DNA strands from denatured duplexes are translocated through engineered protein nanopores at alkaline pH. Nano Lett (2009) 1.17
Catalyzing the translocation of polypeptides through attractive interactions. J Am Chem Soc (2007) 1.17
Stochastic detection of enantiomers. J Am Chem Soc (2006) 1.17
Electrical behavior of droplet interface bilayer networks: experimental analysis and modeling. J Am Chem Soc (2007) 1.15
Simultaneous measurement of ionic current and fluorescence from single protein pores. J Am Chem Soc (2009) 1.14
Folding of a monomeric porin, OmpG, in detergent solution. Biochemistry (2003) 1.14
An engineered ClyA nanopore detects folded target proteins by selective external association and pore entry. Nano Lett (2012) 1.13
The leukocidin pore: evidence for an octamer with four LukF subunits and four LukS subunits alternating around a central axis. Protein Sci (2005) 1.13
Intrinsically disordered protein threads through the bacterial outer-membrane porin OmpF. Science (2013) 1.13
Temperature-responsive protein pores. J Am Chem Soc (2006) 1.10
Properties of Bacillus cereus hemolysin II: a heptameric transmembrane pore. Protein Sci (2002) 1.09
Urea facilitates the translocation of single-stranded DNA and RNA through the alpha-hemolysin nanopore. Biophys J (2010) 1.08
Single-molecule covalent chemistry with spatially separated reactants. Angew Chem Int Ed Engl (2003) 1.08
Direct introduction of single protein channels and pores into lipid bilayers. J Am Chem Soc (2005) 1.07
Membrane-protein structure: Piercing insights. Nature (2009) 1.07
Catalytic subunit of protein kinase A caged at the activating phosphothreonine. J Am Chem Soc (2002) 1.06
Individual RNA base recognition in immobilized oligonucleotides using a protein nanopore. Nano Lett (2012) 1.06
A genetically encoded pore for the stochastic detection of a protein kinase. Chembiochem (2006) 1.04
Nanopore-based identification of individual nucleotides for direct RNA sequencing. Nano Lett (2013) 1.04
Role of the amino latch of staphylococcal alpha-hemolysin in pore formation: a co-operative interaction between the N terminus and position 217. J Biol Chem (2005) 1.03
Stochastic detection of monovalent and bivalent protein-ligand interactions. Angew Chem Int Ed Engl (2004) 1.02
Single-molecule detection of nitrogen mustards by covalent reaction within a protein nanopore. J Am Chem Soc (2008) 1.02
The internal cavity of the staphylococcal alpha-hemolysin pore accommodates approximately 175 exogenous amino acid residues. Biochemistry (2005) 1.01
Stochastic sensing of TNT with a genetically engineered pore. Chembiochem (2005) 0.98
DNA stretching and optimization of nucleobase recognition in enzymatic nanopore sequencing. Nanotechnology (2015) 0.98
Functional truncated membrane pores. Proc Natl Acad Sci U S A (2014) 0.97
Protein components for nanodevices. Curr Opin Chem Biol (2005) 0.97
Translocating kilobase RNA through the Staphylococcal α-hemolysin nanopore. Nano Lett (2013) 0.97
Rapid assembly of a multimeric membrane protein pore. Biophys J (2011) 0.95
Stochastic sensing on a modular chip containing a single-ion channel. Anal Chem (2007) 0.93
Photoisomerization of an individual azobenzene molecule in water: an on-off switch triggered by light at a fixed wavelength. J Am Chem Soc (2006) 0.93
Single-molecule detection of 5-hydroxymethylcytosine in DNA through chemical modification and nanopore analysis. Angew Chem Int Ed Engl (2013) 0.93
Prepore for a breakthrough. Nat Struct Mol Biol (2005) 0.92
Single-molecule interrogation of a bacterial sugar transporter allows the discovery of an extracellular inhibitor. Nat Chem (2013) 0.92
Carriers versus adapters in stochastic sensing. Chemphyschem (2005) 0.92
Nucleobase recognition at alkaline pH and apparent pKa of single DNA bases immobilised within a biological nanopore. Chem Commun (Camb) (2011) 0.91
Altered antibiotic transport in OmpC mutants isolated from a series of clinical strains of multi-drug resistant E. coli. PLoS One (2011) 0.91
Molecular dynamics simulations of DNA within a nanopore: arginine-phosphate tethering and a binding/sliding mechanism for translocation. Biochemistry (2011) 0.91
Single-molecule kinetics of two-step divalent cation chelation. Angew Chem Int Ed Engl (2010) 0.89
Inactivation of the KcsA potassium channel explored with heterotetramers. J Gen Physiol (2010) 0.89
Nanotechnology: Holes with an edge. Nature (2010) 0.88
Orientation of the monomeric porin OmpG in planar lipid bilayers. Chembiochem (2008) 0.88
Tetrameric assembly of KvLm K+ channels with defined numbers of voltage sensors. Proc Natl Acad Sci U S A (2012) 0.87
Formation of a chiral center and pyrimidal inversion at the single-molecule level. Angew Chem Int Ed Engl (2007) 0.87
Porphyrins for probing electrical potential across lipid bilayer membranes by second harmonic generation. Angew Chem Int Ed Engl (2013) 0.85
Rates and stoichiometries of metal ion probes of cysteine residues within ion channels. Biophys J (2013) 0.85
Assembly of the Bi-component leukocidin pore examined by truncation mutagenesis. J Biol Chem (2005) 0.84
Kinetics of a three-step reaction observed at the single-molecule level. Angew Chem Int Ed Engl (2003) 0.84
S-nitrosothiol chemistry at the single-molecule level. Angew Chem Int Ed Engl (2012) 0.84
Tuning the cavity of cyclodextrins: altered sugar adaptors in protein pores. J Am Chem Soc (2011) 0.84
Lipid-coated hydrogel shapes as components of electrical circuits and mechanical devices. Sci Rep (2012) 0.83
Construction and manipulation of functional three-dimensional droplet networks. ACS Nano (2014) 0.83
Continuous stochastic detection of amino acid enantiomers with a protein nanopore. Angew Chem Int Ed Engl (2012) 0.83
Peptide backbone mutagenesis of putative gating hinges in a potassium ion channel. Chembiochem (2008) 0.83
Permeation of styryl dyes through nanometer-scale pores in membranes. Biochemistry (2011) 0.82
An engineered dimeric protein pore that spans adjacent lipid bilayers. Nat Commun (2013) 0.82
Detection of 3'-end RNA uridylation with a protein nanopore. ACS Nano (2013) 0.82
Stochastic detection of Pim protein kinases reveals electrostatically enhanced association of a peptide substrate. Proc Natl Acad Sci U S A (2013) 0.82
A droplet microfluidic system for sequential generation of lipid bilayers and transmembrane electrical recordings. Lab Chip (2015) 0.81
Subunit dimers of alpha-hemolysin expand the engineering toolbox for protein nanopores. J Biol Chem (2011) 0.81
Stepwise growth of a single polymer chain. J Am Chem Soc (2005) 0.81