Published in Virology on June 24, 2008
Coronaviruses: an RNA proofreading machine regulates replication fidelity and diversity. RNA Biol (2011) 1.18
Evolution in health and medicine Sackler colloquium: The comparative genomics of viral emergence. Proc Natl Acad Sci U S A (2009) 1.16
Evolution at a high imposed mutation rate: adaptation obscures the load in phage T7. Genetics (2009) 1.11
The relationship between the error catastrophe, survival of the flattest, and natural selection. BMC Evol Biol (2011) 1.04
Ribavirin can be mutagenic for arenaviruses. J Virol (2011) 1.03
Replication mode and landscape topology differentially affect RNA virus mutational load and robustness. J Virol (2009) 1.01
Therapeutically targeting RNA viruses via lethal mutagenesis. Future Virol (2008) 0.99
Pathways to extinction: beyond the error threshold. Philos Trans R Soc Lond B Biol Sci (2010) 0.97
Inhibition of enveloped virus infection of cultured cells by valproic acid. J Virol (2010) 0.88
Multiple genetic pathways to similar fitness limits during viral adaptation to a new host. Evolution (2011) 0.87
Ribavirin-resistant variants of foot-and-mouth disease virus: the effect of restricted quasispecies diversity on viral virulence. J Virol (2014) 0.86
Does mutational robustness inhibit extinction by lethal mutagenesis in viral populations? PLoS Comput Biol (2010) 0.83
On the possible role of robustness in the evolution of infectious diseases. Chaos (2010) 0.81
Genomic evolution of vesicular stomatitis virus strains with differences in adaptability. J Virol (2010) 0.81
Mutagenesis-mediated virus extinction: virus-dependent effect of viral load on sensitivity to lethal defection. PLoS One (2012) 0.80
Congruent evolution of fitness and genetic robustness in vesicular stomatitis virus. J Virol (2013) 0.77
Empirical complexities in the genetic foundations of lethal mutagenesis. Genetics (2013) 0.77
Lethal mutagenesis failure may augment viral adaptation. Mol Biol Evol (2013) 0.75
Biological and biomedical implications of the co-evolution of pathogens and their hosts. Nat Genet (2002) 4.42
Structure of foot-and-mouth disease virus RNA-dependent RNA polymerase and its complex with a template-primer RNA. J Biol Chem (2004) 2.48
Lethal mutagenesis of the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV). Virology (2003) 1.76
Suppression of viral infectivity through lethal defection. Proc Natl Acad Sci U S A (2005) 1.62
Evolutionary transition toward defective RNAs that are infectious by complementation. J Virol (2004) 1.61
Mutagenesis versus inhibition in the efficiency of extinction of foot-and-mouth disease virus. J Virol (2003) 1.58
Effect of alternating passage on adaptation of sindbis virus to vertebrate and invertebrate cells. J Virol (2005) 1.57
Foot-and-mouth disease virus mutant with decreased sensitivity to ribavirin: implications for error catastrophe. J Virol (2006) 1.56
The structure of a protein primer-polymerase complex in the initiation of genome replication. EMBO J (2006) 1.54
Curing of foot-and-mouth disease virus from persistently infected cells by ribavirin involves enhanced mutagenesis. Virology (2003) 1.44
Sequential structures provide insights into the fidelity of RNA replication. Proc Natl Acad Sci U S A (2007) 1.37
High mutation rates, bottlenecks, and robustness of RNA viral quasispecies. Gene (2005) 1.31
Resistance of virus to extinction on bottleneck passages: study of a decaying and fluctuating pattern of fitness loss. Proc Natl Acad Sci U S A (2003) 1.27
Preextinction viral RNA can interfere with infectivity. J Virol (2004) 1.26
Structural insights into replication initiation and elongation processes by the FMDV RNA-dependent RNA polymerase. Curr Opin Struct Biol (2009) 1.22
Duration and fitness dependence of quasispecies memory. J Mol Biol (2002) 1.18
Insights into RNA virus mutant spectrum and lethal mutagenesis events: replicative interference and complementation by multiple point mutants. J Mol Biol (2007) 1.17
Mutant viral polymerase in the transition of virus to error catastrophe identifies a critical site for RNA binding. J Mol Biol (2005) 1.13
Evidence for quasispecies distributions in the human hepatitis A virus genome. Virology (2003) 1.10
A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape. PLoS Pathog (2010) 1.08
Hidden virulence determinants in a viral quasispecies in vivo. J Virol (2008) 1.06
Ultra-deep pyrosequencing detects conserved genomic sites and quantifies linkage of drug-resistant amino acid changes in the hepatitis B virus genome. PLoS One (2012) 1.06
Potential benefits of sequential inhibitor-mutagen treatments of RNA virus infections. PLoS Pathog (2009) 1.05
Molecular basis for a lack of correlation between viral fitness and cell killing capacity. PLoS Pathog (2007) 1.04
Viral genome segmentation can result from a trade-off between genetic content and particle stability. PLoS Genet (2011) 1.03
Ribavirin can be mutagenic for arenaviruses. J Virol (2011) 1.03
Arenavirus genetic diversity and its biological implications. Infect Genet Evol (2009) 1.03
Initial fitness recovery of HIV-1 is associated with quasispecies heterogeneity and can occur without modifications in the consensus sequence. PLoS One (2010) 1.02
Competition-colonization dynamics in an RNA virus. Proc Natl Acad Sci U S A (2010) 1.01
Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin. J Virol (2010) 1.01
Dynamics of mutation and recombination in a replicating population of complementing, defective viral genomes. J Mol Biol (2006) 1.00
Resistance to extinction of low fitness virus subjected to plaque-to-plaque transfers: diversification by mutation clustering. J Mol Biol (2002) 0.98
Mutagenesis-induced, large fitness variations with an invariant arenavirus consensus genomic nucleotide sequence. J Virol (2005) 0.98
Quasispecies as a matter of fact: viruses and beyond. Virus Res (2011) 0.98
Expansion of host-cell tropism of foot-and-mouth disease virus despite replication in a constant environment. J Gen Virol (2004) 0.97
Pathways to extinction: beyond the error threshold. Philos Trans R Soc Lond B Biol Sci (2010) 0.97
Multidrug-resistant HIV-1 reverse transcriptase: involvement of ribonucleotide-dependent phosphorolysis in cross-resistance to nucleoside analogue inhibitors. J Mol Biol (2002) 0.96
Counteracting quasispecies adaptability: extinction of a ribavirin-resistant virus mutant by an alternative mutagenic treatment. PLoS One (2009) 0.94
Beneficial effects of population bottlenecks in an RNA virus evolving at increased error rate. J Mol Biol (2008) 0.93
Guinea pig-adapted foot-and-mouth disease virus with altered receptor recognition can productively infect a natural host. J Virol (2007) 0.93
Evolution of cell recognition by viruses: a source of biological novelty with medical implications. Adv Virus Res (2003) 0.92
Lethal mutagenesis of viruses. Curr Opin Virol (2011) 0.92
Combination of a mutagenic agent with a reverse transcriptase inhibitor results in systematic inhibition of HIV-1 infection. Virology (2005) 0.92
Minority report: hidden memory genomes in HIV-1 quasispecies and possible clinical implications. AIDS Rev (2008) 0.92
Adaptability costs in immune escape variants of vesicular stomatitis virus. Virus Res (2005) 0.92
Mutation hot spots in hepatitis B surface antigen in chronic carriers from Khoozestan province, southern of Iran. Iran J Allergy Asthma Immunol (2013) 0.92
The impact of quasispecies dynamics on the use of therapeutics. Trends Microbiol (2012) 0.91
Fitness increase of memory genomes in a viral quasispecies. J Mol Biol (2004) 0.91
Evidence of the coevolution of antigenicity and host cell tropism of foot-and-mouth disease virus in vivo. J Virol (2003) 0.90
Invariant aphthovirus consensus nucleotide sequence in the transition to error catastrophe. Infect Genet Evol (2005) 0.90
Repeated bottleneck transfers can lead to non-cytocidal forms of a cytopathic virus: implications for viral extinction. J Mol Biol (2007) 0.90
Modeling viral genome fitness evolution associated with serial bottleneck events: evidence of stationary states of fitness. J Virol (2002) 0.90
High variability and rapid evolution of a nanovirus. J Virol (2010) 0.89
Molecular characterization of a dual inhibitory and mutagenic activity of 5-fluorouridine triphosphate on viral RNA synthesis. Implications for lethal mutagenesis. J Mol Biol (2008) 0.89
A segmented form of foot-and-mouth disease virus interferes with standard virus: a link between interference and competitive fitness. Virology (2005) 0.88
Topology of evolving, mutagenized viral populations: quasispecies expansion, compression, and operation of negative selection. BMC Evol Biol (2008) 0.88
Response of hepatitis C virus to long-term passage in the presence of alpha interferon: multiple mutations and a common phenotype. J Virol (2013) 0.88
Synchronous loss of quasispecies memory in parallel viral lineages: a deterministic feature of viral quasispecies. J Mol Biol (2003) 0.88
Fitness distributions in exponentially growing asexual populations. Phys Rev Lett (2003) 0.87
Deletion mutants of VPg reveal new cytopathology determinants in a picornavirus. PLoS One (2010) 0.87
An interfering activity against lymphocytic choriomeningitis virus replication associated with enhanced mutagenesis. J Gen Virol (2009) 0.86
Minority memory genomes can influence the evolution of HIV-1 quasispecies in vivo. Gene (2006) 0.86
Few mutations in the 5' leader region mediate fitness recovery of debilitated human immunodeficiency type 1 viruses. J Virol (2005) 0.86
Influence of mutagenesis and viral load on the sustained low-level replication of an RNA virus. J Mol Biol (2011) 0.85
Biological effect of Muller's Ratchet: distant capsid site can affect picornavirus protein processing. J Virol (2009) 0.85
5-fluorouracil in lethal mutagenesis of foot-and-mouth disease virus. Future Med Chem (2009) 0.84
Reconstitution of authentic nanovirus from multiple cloned DNAs. J Virol (2009) 0.84
Memory in retroviral quasispecies: experimental evidence and theoretical model for human immunodeficiency virus. J Mol Biol (2003) 0.84
Monitoring sequence space as a test for the target of selection in viruses. J Mol Biol (2005) 0.84
Tempo and mode of inhibitor-mutagen antiviral therapies: a multidisciplinary approach. Proc Natl Acad Sci U S A (2011) 0.83
Transdisciplinary EU science institute needs funds urgently. Nature (2010) 0.83
Future prospects for the treatment of rapidly evolving viral pathogens: insights from evolutionary biology. Expert Opin Biol Ther (2008) 0.82
Analysis of sequential hepatitis A virus strains reveals coexistence of distinct viral subpopulations. J Gen Virol (2006) 0.82
Persistence of foot-and-mouth disease virus in cell culture revisited: implications for contingency in evolution. J Gen Virol (2008) 0.82
Viral fitness can influence the repertoire of virus variants selected by antibodies. J Mol Biol (2006) 0.81
Microarray-based identification of antigenic variants of foot-and-mouth disease virus: a bioinformatics quality assessment. BMC Genomics (2006) 0.81
Extinction of hepatitis C virus by ribavirin in hepatoma cells involves lethal mutagenesis. PLoS One (2013) 0.81
Identification of host and viral factors involved in a dissimilar resolution of a hepatitis C virus infection. Liver Int (2013) 0.80
Competition-colonization dynamics: An ecology approach to quasispecies dynamics and virulence evolution in RNA viruses. Commun Integr Biol (2010) 0.80
Mutagenesis-mediated virus extinction: virus-dependent effect of viral load on sensitivity to lethal defection. PLoS One (2012) 0.80
Influence of the mutant spectrum in viral evolution: focused selection of antigenic variants in a reconstructed viral quasispecies. Mol Biol Evol (2008) 0.79
Characterization of minority subpopulations in the mutant spectrum of HIV-1 quasispecies by successive specific amplifications. Virus Res (2007) 0.79
Arenaviruses and lethal mutagenesis. Prospects for new ribavirin-based interventions. Viruses (2012) 0.79
New vaccine design based on defective genomes that combines features of attenuated and inactivated vaccines. PLoS One (2010) 0.79
Exploration of sequence space as the basis of viral RNA genome segmentation. Proc Natl Acad Sci U S A (2014) 0.78
Quasispecies dynamics in hepatitis C liver transplant recipients receiving grafts from hepatitis C virus infected donors. J Gen Virol (2015) 0.78
Virus evolution. Curr Opin Virol (2011) 0.78
Evidence of Muller's ratchet in herpes simplex virus type 1. J Gen Virol (2012) 0.78
Lethal mutagenesis of foot-and-mouth disease virus involves shifts in sequence space. J Virol (2011) 0.78
Populations of genomic RNAs devoted to the replication or spread of a bipartite plant virus differ in genetic structure. J Virol (2009) 0.77
Molecular dissection of a viral quasispecies under mutagenic treatment: positive correlation between fitness loss and mutational load. J Gen Virol (2012) 0.77
Mutagen-mediated enhancement of HIV-1 replication in persistently infected cells. Virology (2012) 0.77
Cell density-dependent expression of viral antigens during persistence of foot-and-mouth disease virus in cell culture. Virology (2010) 0.76