The antiparallel loops in gal DNA.

PubWeight™: 1.02‹?› | Rank: Top 15%

🔗 View Article (PMC 2475638)

Published in Nucleic Acids Res on June 23, 2008

Authors

Giuseppe Lia1, Szabolcs Semsey, Dale E A Lewis, Sankar Adhya, David Bensimon, David Dunlap, Laura Finzi

Author Affiliations

1: Department of Chemistry, Harvard University, Cambridge, MA, USA.

Articles cited by this

Genetic regulatory mechanisms in the synthesis of proteins. J Mol Biol (1961) 65.10

Direct mechanical measurements of the elasticity of single DNA molecules by using magnetic beads. Science (1992) 9.74

The elasticity of a single supercoiled DNA molecule. Science (1996) 8.58

Force and velocity measured for single molecules of RNA polymerase. Science (1998) 7.15

DNA flexibility studied by covalent closure of short fragments into circles. Proc Natl Acad Sci U S A (1981) 5.44

Behavior of supercoiled DNA. Biophys J (1998) 4.86

Mechanism of action of the cro protein of bacteriophage lambda. Proc Natl Acad Sci U S A (1978) 4.34

Crystal structure of lac repressor core tetramer and its implications for DNA looping. Science (1995) 4.08

Structure and function of the interferon-beta enhanceosome. Cold Spring Harb Symp Quant Biol (1998) 3.81

Groucho proteins: transcriptional corepressors for specific subsets of DNA-binding transcription factors in vertebrates and invertebrates. Genes Dev (1998) 2.92

Transcriptional repression: the long and the short of it. Genes Dev (2001) 2.91

Investigation of the flexibility of DNA using transient electric birefringence. Biopolymers (1981) 2.74

Octamerization of lambda CI repressor is needed for effective repression of P(RM) and efficient switching from lysogeny. Genes Dev (2001) 2.53

Inhibition of transcription initiation by lac repressor. J Mol Biol (1995) 2.13

DNA looping in gene regulation: from the assembly of macromolecular complexes to the control of transcriptional noise. Curr Opin Genet Dev (2005) 2.03

Lambda Int protein bridges between higher order complexes at two distant chromosomal loci attL and attR. Science (1992) 2.01

Repressor induced site-specific binding of HU for transcriptional regulation. EMBO J (1997) 1.94

Direct observation of DNA distortion by the RSC complex. Mol Cell (2006) 1.89

The functional subunit of a dimeric transcription activator protein depends on promoter architecture. EMBO J (1994) 1.70

Control of gal transcription through DNA looping: inhibition of the initial transcribing complex. Proc Natl Acad Sci U S A (1992) 1.65

Homologous pairing in stretched supercoiled DNA. Proc Natl Acad Sci U S A (1998) 1.63

Supercoiling and denaturation in Gal repressor/heat unstable nucleoid protein (HU)-mediated DNA looping. Proc Natl Acad Sci U S A (2003) 1.63

Efficient recruitment of TFIIB and CBP-RNA polymerase II holoenzyme by an interferon-beta enhanceosome in vitro. Proc Natl Acad Sci U S A (1998) 1.54

Gal repressosome contains an antiparallel DNA loop. Nat Struct Biol (2001) 1.48

Identification of the functional subunit of a dimeric transcription activator protein by use of oriented heterodimers. Cell (1993) 1.46

Anatomy of a flexer-DNA complex inside a higher-order transposition intermediate. Cell (1996) 1.41

Designed hyperstable Lac repressor.DNA loop topologies suggest alternative loop geometries. J Mol Biol (1999) 1.34

A gamut of loops: meandering DNA. Trends Biochem Sci (2005) 1.33

Operator-bound GalR dimers close DNA loops by direct interaction: tetramerization and inducer binding. EMBO J (2002) 1.21

"Antiparallel" DNA loop in gal repressosome visualized by atomic force microscopy. J Mol Biol (2003) 1.17

Stress-induced structural transitions in DNA and proteins. Annu Rev Biophys Biomol Struct (2000) 1.10

DNA trajectory in the Gal repressosome. Genes Dev (2004) 1.08

GalR mutants defective in repressosome formation. Genes Dev (1999) 1.06

Transcription regulation by inflexibility of promoter DNA in a looped complex. Proc Natl Acad Sci U S A (1995) 1.05

Single base-pair precision and structural rigidity in a small IHF-induced DNA loop. J Mol Biol (1995) 0.99

GalR represses galP1 by inhibiting the rate-determining open complex formation through RNA polymerase contact: a GalR negative control mutant. J Mol Biol (2004) 0.98

Genetic analysis of GalR tetramerization in DNA looping during repressosome assembly. J Biol Chem (2002) 0.97

Geometric and dynamic requirements for DNA looping, wrapping and unwrapping in the activation of E.coli glnAp2 transcription by NtrC. J Mol Biol (2004) 0.95

Identification of the subunit of cAMP receptor protein (CRP) that functionally interacts with CytR in CRP-CytR-mediated transcriptional repression. J Biol Chem (2000) 0.81

Do femtonewton forces affect genetic function? A review. J Biol Phys (2006) 0.79

Articles by these authors

Switches in bacteriophage lambda development. Annu Rev Genet (2005) 3.24

Bacteriophage therapy rescues mice bacteremic from a clinical isolate of vancomycin-resistant Enterococcus faecium. Infect Immun (2002) 2.52

Single-molecule assay reveals strand switching and enhanced processivity of UvrD. Proc Natl Acad Sci U S A (2004) 2.24

Direct observation of DNA distortion by the RSC complex. Mol Cell (2006) 1.89

Tethered particle motion as a diagnostic of DNA tether length. J Phys Chem B (2006) 1.88

Real-time observation of bacteriophage T4 gp41 helicase reveals an unwinding mechanism. Proc Natl Acad Sci U S A (2007) 1.76

Measurement of the torque on a single stretched and twisted DNA using magnetic tweezers. Phys Rev Lett (2009) 1.65

On the role of Cro in lambda prophage induction. Proc Natl Acad Sci U S A (2005) 1.65

Supercoiling and denaturation in Gal repressor/heat unstable nucleoid protein (HU)-mediated DNA looping. Proc Natl Acad Sci U S A (2003) 1.63

Direct demonstration and quantification of long-range DNA looping by the lambda bacteriophage repressor. Nucleic Acids Res (2009) 1.49

Toward a live microbial microbicide for HIV: commensal bacteria secreting an HIV fusion inhibitor peptide. Proc Natl Acad Sci U S A (2005) 1.39

High-sensitivity bacterial detection using biotin-tagged phage and quantum-dot nanocomplexes. Proc Natl Acad Sci U S A (2006) 1.36

Active and passive mechanisms of helicases. Nucleic Acids Res (2010) 1.35

A gamut of loops: meandering DNA. Trends Biochem Sci (2005) 1.33

Efficient degradation and expression prioritization with small RNAs. Phys Biol (2007) 1.33

Simplified models of biological networks. Annu Rev Biophys (2010) 1.33

Escherichia coli K1's capsule is a barrier to bacteriophage T7. Appl Environ Microbiol (2005) 1.31

Intracellular entrapment of wild-type TSH receptor by oligomerization with mutants linked to dominant TSH resistance. Hum Mol Genet (2005) 1.30

DNA looping kinetics analyzed using diffusive hidden Markov model. Biophys J (2007) 1.29

Wringing out DNA. Phys Rev Lett (2006) 1.29

Axiom of determining transcription start points by RNA polymerase in Escherichia coli. Mol Microbiol (2004) 1.27

Three-stage regulation of the amphibolic gal operon: from repressosome to GalR-free DNA. J Mol Biol (2006) 1.25

Stretching DNA and RNA to probe their interactions with proteins. Curr Opin Struct Biol (2003) 1.25

Bacteriophage infection is targeted to cellular poles. Mol Microbiol (2008) 1.25

Signal integration in the galactose network of Escherichia coli. Mol Microbiol (2007) 1.25

Recognition of the tumor suppressor protein p53 and other protein targets by the calcium-binding protein S100B. Biochim Biophys Acta (2006) 1.24

Dynamic features of gene expression control by small regulatory RNAs. Proc Natl Acad Sci U S A (2009) 1.23

In vitro repression of the gal promoters by GalR and HU depends on the proper helical phasing of the two operators. J Biol Chem (2001) 1.22

A mutant spacer sequence between -35 and -10 elements makes the Plac promoter hyperactive and cAMP receptor protein-independent. Proc Natl Acad Sci U S A (2004) 1.22

A-tract clusters may facilitate DNA packaging in bacterial nucleoid. Nucleic Acids Res (2005) 1.21

Operator-bound GalR dimers close DNA loops by direct interaction: tetramerization and inducer binding. EMBO J (2002) 1.21

Genetic flexibility of regulatory networks. Proc Natl Acad Sci U S A (2010) 1.20

Nucleoid remodeling by an altered HU protein: reorganization of the transcription program. Proc Natl Acad Sci U S A (2005) 1.20

Spiral structure of Escherichia coli HUalphabeta provides foundation for DNA supercoiling. Proc Natl Acad Sci U S A (2007) 1.18

Multilevel autoregulation of λ repressor protein CI by DNA looping in vitro. Proc Natl Acad Sci U S A (2011) 1.18

"Antiparallel" DNA loop in gal repressosome visualized by atomic force microscopy. J Mol Biol (2003) 1.17

Photoactivation of the CreER T2 recombinase for conditional site-specific recombination with high spatiotemporal resolution. Zebrafish (2010) 1.16

BASIC PENTACYSTEINE1, a GA binding protein that induces conformational changes in the regulatory region of the homeotic Arabidopsis gene SEEDSTICK. Plant Cell (2005) 1.14

DNA mechanics as a tool to probe helicase and translocase activity. Nucleic Acids Res (2006) 1.13

Effect of varying the supercoiling of DNA on transcription and its regulation. Biochemistry (2003) 1.12

Combinatorics of feedback in cellular uptake and metabolism of small molecules. Proc Natl Acad Sci U S A (2007) 1.11

Single-molecule studies of DNA architectural changes induced by regulatory proteins. Methods Enzymol (2003) 1.10

Cellular stress created by intermediary metabolite imbalances. Proc Natl Acad Sci U S A (2009) 1.09

DNA trajectory in the Gal repressosome. Genes Dev (2004) 1.08

Mechanism of strand displacement synthesis by DNA replicative polymerases. Nucleic Acids Res (2012) 1.07

Cell-cell contacts confine public goods diffusion inside Pseudomonas aeruginosa clonal microcolonies. Proc Natl Acad Sci U S A (2013) 1.04

Single-molecule mechanical identification and sequencing. Nat Methods (2012) 1.04

AFM studies of lambda repressor oligomers securing DNA loops. Curr Pharm Biotechnol (2009) 1.03

Why do phage play dice? J Virol (2009) 1.03

Right-handed DNA supercoiling by an octameric form of histone-like protein HU: modulation of cellular transcription. J Biol Chem (2006) 1.02

Quantitative analysis of DNA-looping kinetics from tethered particle motion experiments. Methods Enzymol (2010) 1.01

Identification of host receptor and receptor-binding module of a newly sequenced T5-like phage EPS7. FEMS Microbiol Lett (2008) 1.00

Positively charged surfaces increase the flexibility of DNA. Biophys J (2005) 1.00

Genetic instability favoring transversions associated with ErbB2-induced mammary tumorigenesis. Proc Natl Acad Sci U S A (2002) 0.99

The effect of nonspecific binding of lambda repressor on DNA looping dynamics. Biophys J (2012) 0.98

GalR represses galP1 by inhibiting the rate-determining open complex formation through RNA polymerase contact: a GalR negative control mutant. J Mol Biol (2004) 0.98

Genetic analysis of GalR tetramerization in DNA looping during repressosome assembly. J Biol Chem (2002) 0.97

DNA compaction by the nuclear factor-Y. Biophys J (2007) 0.97

Ribosomal protein S1 promotes transcriptional cycling. RNA (2006) 0.97

Host responses influence on the induction of lambda prophage. Mol Microbiol (2008) 0.97

Single DNA/protein studies with magnetic traps. Curr Opin Struct Biol (2009) 0.96

Diffusion of light-harvesting complex II in the thylakoid membranes. EMBO Rep (2005) 0.96

Fluorescence resonance energy transfer detection of synaptophysin I and vesicle-associated membrane protein 2 interactions during exocytosis from single live synapses. Mol Biol Cell (2002) 0.95

Bacteriophage SP6 is closely related to phages K1-5, K5, and K1E but encodes a tail protein very similar to that of the distantly related P22. J Bacteriol (2002) 0.94

Conversion of commensal Escherichia coli K-12 to an invasive form via expression of a mutant histone-like protein. MBio (2011) 0.94

Sequestration of toxic oligomers by HspB1 as a cytoprotective mechanism. Mol Cell Biol (2011) 0.94

Asynchronous basepair openings in transcription initiation: CRP enhances the rate-limiting step. EMBO J (2004) 0.94

Architectural organization in E. coli nucleoid. Biochim Biophys Acta (2012) 0.94

Structure and function of negative feedback loops at the interface of genetic and metabolic networks. Nucleic Acids Res (2006) 0.93

High-density functional display of proteins on bacteriophage lambda. J Mol Biol (2003) 0.93

Photocontrol of protein activity in cultured cells and zebrafish with one- and two-photon illumination. Chembiochem (2010) 0.93

Noncoding RNAs binding to the nucleoid protein HU in Escherichia coli. J Bacteriol (2012) 0.93

Genome-wide screening of genes regulated by DNA methylation in colon cancer development. PLoS One (2012) 0.92

Galactose repressor mediated intersegmental chromosomal connections in Escherichia coli. Proc Natl Acad Sci U S A (2012) 0.92

Evolution of DNA binding motifs and operators. Gene (2002) 0.91

Direct and indirect effects in the regulation of overlapping promoters. Nucleic Acids Res (2011) 0.91

Dominant negative autoregulation limits steady-state repression levels in gene networks. J Bacteriol (2009) 0.91

Integration host factor alters LacI-induced DNA looping. Biophys Chem (2007) 0.91

An amino acid substitution in a capsid protein enhances phage survival in mouse circulatory system more than a 1000-fold. Virus Res (2005) 0.91

Relation of intracellular signal levels and promoter activities in the gal regulon of Escherichia coli. J Mol Biol (2009) 0.90

Determination of the number of proteins bound non-specifically to DNA. J Phys Condens Matter (2010) 0.90