| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
A single-molecule nanopore device detects DNA polymerase activity with single-nucleotide resolution.
|
J Am Chem Soc
|
2008
|
3.04
|
|
2
|
Recognizing a single base in an individual DNA strand: a step toward DNA sequencing in nanopores.
|
Angew Chem Int Ed Engl
|
2005
|
2.83
|
|
3
|
A virocidal amphipathic {alpha}-helical peptide that inhibits hepatitis C virus infection in vitro.
|
Proc Natl Acad Sci U S A
|
2008
|
1.48
|
|
4
|
Single DNA rotaxanes of a transmembrane pore protein.
|
Angew Chem Int Ed Engl
|
2004
|
1.48
|
|
5
|
Self-assembling peptide nanotubes with antiviral activity against hepatitis C virus.
|
Chem Biol
|
2011
|
1.41
|
|
6
|
Heterocyclic peptide backbone modifications in an alpha-helical coiled coil.
|
J Am Chem Soc
|
2004
|
1.33
|
|
7
|
Systemic antibacterial activity of novel synthetic cyclic peptides.
|
Antimicrob Agents Chemother
|
2005
|
1.25
|
|
8
|
Modular multi-level circuits from immobilized DNA-based logic gates.
|
J Am Chem Soc
|
2007
|
1.23
|
|
9
|
Carbonyl sulfide-mediated prebiotic formation of peptides.
|
Science
|
2004
|
1.22
|
|
10
|
Self-assembling sequence-adaptive peptide nucleic acids.
|
Science
|
2009
|
1.21
|
|
11
|
Coiled coils at the edge of configurational heterogeneity. Structural analyses of parallel and antiparallel homotetrameric coiled coils reveal configurational sensitivity to a single solvent-exposed amino acid substitution.
|
Biochemistry
|
2006
|
1.21
|
|
12
|
Discovery of a biologically active thiostrepton fragment.
|
J Am Chem Soc
|
2005
|
1.20
|
|
13
|
A heterocyclic peptide nanotube.
|
J Am Chem Soc
|
2003
|
1.14
|
|
14
|
Design of a directed molecular network.
|
Proc Natl Acad Sci U S A
|
2004
|
1.13
|
|
15
|
Boolean logic functions of a synthetic peptide network.
|
J Am Chem Soc
|
2004
|
1.10
|
|
16
|
Probing the bioactive conformation of an archetypal natural product HDAC inhibitor with conformationally homogeneous triazole-modified cyclic tetrapeptides.
|
Angew Chem Int Ed Engl
|
2009
|
1.08
|
|
17
|
DNA-based photonic logic gates: AND, NAND, and INHIBIT.
|
J Am Chem Soc
|
2003
|
1.08
|
|
18
|
DNA detection and signal amplification via an engineered allosteric enzyme.
|
J Am Chem Soc
|
2003
|
1.08
|
|
19
|
Real-time monitoring of DNA polymerase function and stepwise single-nucleotide DNA strand translocation through a protein nanopore.
|
Angew Chem Int Ed Engl
|
2010
|
1.03
|
|
20
|
Automated mass spectrometric sequence determination of cyclic peptide library members.
|
J Comb Chem
|
2003
|
1.02
|
|
21
|
Antiviral cyclic D,L-alpha-peptides: targeting a general biochemical pathway in virus infections.
|
Bioorg Med Chem
|
2005
|
1.02
|
|
22
|
Design of self-assembling peptide nanotubes with delocalized electronic states.
|
Small
|
2006
|
1.02
|
|
23
|
Discovery of potent and selective histone deacetylase inhibitors via focused combinatorial libraries of cyclic alpha3beta-tetrapeptides.
|
J Med Chem
|
2009
|
1.02
|
|
24
|
Molecules that mimic apolipoprotein A-I: potential agents for treating atherosclerosis.
|
J Med Chem
|
2013
|
0.98
|
|
25
|
Sequence-addressable DNA logic.
|
Small
|
2008
|
0.98
|
|
26
|
Structure-based engineering of internal cavities in coiled-coil peptides.
|
Biochemistry
|
2005
|
0.97
|
|
27
|
Mimicry of high-density lipoprotein: functional peptide-lipid nanoparticles based on multivalent peptide constructs.
|
J Am Chem Soc
|
2013
|
0.94
|
|
28
|
Ion channel models based on self-assembling cyclic peptide nanotubes.
|
Acc Chem Res
|
2013
|
0.94
|
|
29
|
Efficient route to C2 symmetric heterocyclic backbone modified cyclic peptides.
|
Org Lett
|
2005
|
0.93
|
|
30
|
Modulating ion channel properties of transmembrane peptide nanotubes through heteromeric supramolecular assemblies.
|
J Am Chem Soc
|
2002
|
0.92
|
|
31
|
Catalyzed oxidative corrosion of porous silicon used as an optical transducer for ligand-receptor interactions.
|
Chembiochem
|
2008
|
0.90
|
|
32
|
Conformationally homogeneous heterocyclic pseudotetrapeptides as three-dimensional scaffolds for rational drug design: receptor-selective somatostatin analogues.
|
Angew Chem Int Ed Engl
|
2009
|
0.90
|
|
33
|
Universal translators for nucleic acid diagnosis.
|
J Am Chem Soc
|
2009
|
0.88
|
|
34
|
Design, synthesis, biological evaluation, and structural characterization of potent histone deacetylase inhibitors based on cyclic alpha/beta-tetrapeptide architectures.
|
J Am Chem Soc
|
2009
|
0.86
|
|
35
|
Design of molecular logic devices based on a programmable DNA-regulated semisynthetic enzyme.
|
Angew Chem Int Ed Engl
|
2007
|
0.84
|
|
36
|
Modulating charge transfer through cyclic D,L-alpha-peptide self-assembly.
|
Chemistry
|
2005
|
0.83
|
|
37
|
Amino acid dependent formation of phosphate anhydrides in water mediated by carbonyl sulfide.
|
J Am Chem Soc
|
2006
|
0.83
|
|
38
|
Potential Agents for Treating Cystic Fibrosis: Cyclic Tetrapeptides that Restore Trafficking and Activity of ΔF508-CFTR.
|
ACS Med Chem Lett
|
2011
|
0.82
|
|
39
|
A combinatorial approach to the discovery of biocidal six-residue cyclic D,L-alpha-peptides against the bacteria methicillin-resistant Staphylococcus aureus (MRSA) and E. coli and the biofouling algae Ulva linza and Navicula perminuta.
|
Chemistry
|
2007
|
0.82
|
|
40
|
Antibacterial cyclic D,L-alpha-glycopeptides.
|
Chem Commun (Camb)
|
2009
|
0.80
|
|
41
|
Biomimetic catalysis of intermodular aminoacyl transfer.
|
J Am Chem Soc
|
2007
|
0.78
|
|
42
|
Functional and mechanistic analyses of biomimetic aminoacyl transfer reactions in de novo designed coiled coil peptides via rational active site engineering.
|
J Am Chem Soc
|
2007
|
0.78
|
|
43
|
Biomimetic catalysis of diketopiperazine and dipeptide syntheses.
|
Angew Chem Int Ed Engl
|
2008
|
0.75
|
|
44
|
Dynamic polythioesters via ring-opening polymerization of 1,4-thiazine-2,5-diones.
|
Org Biomol Chem
|
2009
|
0.75
|
|
45
|
Synthesis of photoactive p-azidotetrafluorophenylalanine containing peptide by solid-phase Fmoc methodology.
|
Org Lett
|
2002
|
0.75
|
|
46
|
Templated Self-Assembly of Dynamic Peptide Nucleic Acids.
|
Biochemistry
|
2017
|
0.75
|