Published in Respir Med on June 01, 2008
Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med (2012) 22.96
Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease. N Engl J Med (2007) 19.86
Susceptibility to exacerbation in chronic obstructive pulmonary disease. N Engl J Med (2010) 15.07
Azithromycin for prevention of exacerbations of COPD. N Engl J Med (2011) 8.66
Lebrikizumab treatment in adults with asthma. N Engl J Med (2011) 8.07
Genetic epidemiology of COPD (COPDGene) study design. COPD (2010) 7.67
Effect of pharmacotherapy on rate of decline of lung function in chronic obstructive pulmonary disease: results from the TORCH study. Am J Respir Crit Care Med (2008) 6.17
Pulmonary Rehabilitation: Joint ACCP/AACVPR Evidence-Based Clinical Practice Guidelines. Chest (2007) 5.01
An official American Thoracic Society/European Respiratory Society statement: key concepts and advances in pulmonary rehabilitation. Am J Respir Crit Care Med (2013) 4.49
Chronic obstructive pulmonary disease phenotypes: the future of COPD. Am J Respir Crit Care Med (2010) 4.19
GOLD 2011 disease severity classification in COPDGene: a prospective cohort study. Lancet Respir Med (2012) 3.98
Predictors of mortality in patients with emphysema and severe airflow obstruction. Am J Respir Crit Care Med (2006) 3.71
An official American Thoracic Society statement: update on the mechanisms, assessment, and management of dyspnea. Am J Respir Crit Care Med (2012) 3.62
Simvastatin for the prevention of exacerbations in moderate-to-severe COPD. N Engl J Med (2014) 3.51
Six-minute-walk test in chronic obstructive pulmonary disease: minimal clinically important difference for death or hospitalization. Am J Respir Crit Care Med (2012) 3.44
Chronic obstructive pulmonary disease exacerbations in the COPDGene study: associated radiologic phenotypes. Radiology (2011) 3.30
Smoking cessation with varenicline, a selective alpha4beta2 nicotinic receptor partial agonist: results from a 7-week, randomized, placebo- and bupropion-controlled trial with 1-year follow-up. Arch Intern Med (2006) 3.30
Efficacy and safety of the novel selective nicotinic acetylcholine receptor partial agonist, varenicline, for smoking cessation. Arch Intern Med (2006) 3.30
Usefulness of the Chronic Obstructive Pulmonary Disease Assessment Test to evaluate severity of COPD exacerbations. Am J Respir Crit Care Med (2012) 3.09
Survival after shock therapy in implantable cardioverter-defibrillator and cardiac resynchronization therapy-defibrillator recipients according to rhythm shocked. The ALTITUDE survival by rhythm study. J Am Coll Cardiol (2013) 3.03
Single maintenance and reliever therapy (SMART) of asthma: a critical appraisal. Thorax (2010) 2.86
Sex differences in severe pulmonary emphysema. Am J Respir Crit Care Med (2007) 2.77
Germline mutations and sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk. Nat Genet (2002) 2.76
Development and Validation of an Improved, COPD-Specific Version of the St. George Respiratory Questionnaire. Chest (2007) 2.67
Predictors of rehospitalization and death after a severe exacerbation of COPD. Chest (2007) 2.67
Once-daily bronchodilators for chronic obstructive pulmonary disease: indacaterol versus tiotropium. Am J Respir Crit Care Med (2010) 2.56
Long-term outcome after ICD and CRT implantation and influence of remote device follow-up: the ALTITUDE survival study. Circulation (2010) 2.45
Withdrawal from treatment as an outcome in the ISOLDE study of COPD. Chest (2003) 2.44
Anxiety and depression in COPD: current understanding, unanswered questions, and research needs. Chest (2008) 2.37
Prevention of acute exacerbations of COPD: American College of Chest Physicians and Canadian Thoracic Society Guideline. Chest (2015) 2.32
Efficacy of salmeterol/fluticasone propionate by GOLD stage of chronic obstructive pulmonary disease: analysis from the randomised, placebo-controlled TORCH study. Respir Res (2009) 2.31
Brain structure and function in chronic obstructive pulmonary disease: a multimodal cranial magnetic resonance imaging study. Am J Respir Crit Care Med (2012) 2.27
Association between genetic polymorphisms in the prostate-specific antigen gene promoter and serum prostate-specific antigen levels. J Natl Cancer Inst (2003) 2.26
Prevalence and progression of osteoporosis in patients with COPD: results from the TOwards a Revolution in COPD Health study. Chest (2009) 2.20
Standardizing measurement of chronic obstructive pulmonary disease exacerbations. Reliability and validity of a patient-reported diary. Am J Respir Crit Care Med (2010) 2.09
A combined pulmonary-radiology workshop for visual evaluation of COPD: study design, chest CT findings and concordance with quantitative evaluation. COPD (2012) 2.07
Early-onset chronic obstructive pulmonary disease is associated with female sex, maternal factors, and African American race in the COPDGene Study. Am J Respir Crit Care Med (2011) 2.06
Safety and immunogenicity of a nicotine conjugate vaccine in current smokers. Clin Pharmacol Ther (2005) 2.04
Variability of a closed, rebreathing setup for multiple breath wash-out testing in children. Pediatr Pulmonol (2012) 2.03
Minimal clinically important differences in pharmacological trials. Am J Respir Crit Care Med (2014) 2.00
Design of the Subpopulations and Intermediate Outcomes in COPD Study (SPIROMICS). Thorax (2013) 1.99
Health status assessment in routine clinical practice: the chronic obstructive pulmonary disease assessment test score in outpatients. Respiration (2012) 1.99
Inflammatory biomarkers improve clinical prediction of mortality in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2012) 1.99
A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13. Hum Mol Genet (2011) 1.98
Genetic association analysis of functional impairment in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2006) 1.98
Genetic determinants of emphysema distribution in the national emphysema treatment trial. Am J Respir Crit Care Med (2007) 1.94
Cardiac resynchronization therapy and the relationship of percent biventricular pacing to symptoms and survival. Heart Rhythm (2011) 1.93
Heart failure decompensation and all-cause mortality in relation to percent biventricular pacing in patients with heart failure: is a goal of 100% biventricular pacing necessary? J Am Coll Cardiol (2009) 1.79
Effects of sustained-release bupropion among persons interested in reducing but not quitting smoking. Am J Med (2004) 1.76
Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2012) 1.72
Bronchodilator responsiveness as a phenotypic characteristic of established chronic obstructive pulmonary disease. Thorax (2012) 1.72
Real world evaluation of dual-zone ICD and CRT-D programming compared to single-zone programming: the ALTITUDE REDUCES study. J Cardiovasc Electrophysiol (2011) 1.69
Gender differences of airway dimensions in anatomically matched sites on CT in smokers. COPD (2011) 1.66
Chronic obstructive pulmonary disease biomarker(s) for disease activity needed--urgently. Am J Respir Crit Care Med (2010) 1.66
COPD as a lung disease with systemic consequences--clinical impact, mechanisms, and potential for early intervention. COPD (2008) 1.65
The effect of helium and oxygen on exercise performance in chronic obstructive pulmonary disease: a randomized crossover trial. Am J Respir Crit Care Med (2006) 1.65
Racial differences in quality of life in patients with COPD. Chest (2011) 1.64
An Official American Thoracic Society/European Respiratory Society Statement: Research questions in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2015) 1.63
Pathophysiology of dyspnea in chronic obstructive pulmonary disease: a roundtable. Proc Am Thorac Soc (2007) 1.56
The COPD assessment test (CAT): response to pulmonary rehabilitation. A multicentre, prospective study. Thorax (2011) 1.54
Beta2-adrenoceptor signaling is required for the development of an asthma phenotype in a murine model. Proc Natl Acad Sci U S A (2009) 1.53
The IBV Valve trial: a multicenter, randomized, double-blind trial of endobronchial therapy for severe emphysema. J Bronchology Interv Pulmonol (2014) 1.51
Relationship between FEV1 change and patient-reported outcomes in randomised trials of inhaled bronchodilators for stable COPD: a systematic review. Respir Res (2011) 1.51
Bronchial thermoplasty: Long-term safety and effectiveness in patients with severe persistent asthma. J Allergy Clin Immunol (2013) 1.45
Gender differences in the management and experience of Chronic Obstructive Pulmonary Disease. Respir Med (2004) 1.37
The effects of cigarette smoke on airway inflammation in asthma and COPD: therapeutic implications. Respir Med (2011) 1.36
Identifying and characterizing COPD patients in US managed care. A retrospective, cross-sectional analysis of administrative claims data. BMC Health Serv Res (2011) 1.36
Sex differences in mortality and clinical expressions of patients with chronic obstructive pulmonary disease. The TORCH experience. Am J Respir Crit Care Med (2010) 1.33
Oxygen therapy for patients with COPD: current evidence and the long-term oxygen treatment trial. Chest (2010) 1.31
Effect of fluticasone propionate/salmeterol on lung hyperinflation and exercise endurance in COPD. Chest (2006) 1.30
Predicting outcomes from 6-minute walk distance in chronic obstructive pulmonary disease. J Am Med Dir Assoc (2011) 1.28
Sputum neutrophils as a biomarker in COPD: findings from the ECLIPSE study. Respir Res (2010) 1.26
Variable DNA methylation is associated with chronic obstructive pulmonary disease and lung function. Am J Respir Crit Care Med (2011) 1.26
Pathogenesis of emphysema: from the bench to the bedside. Proc Am Thorac Soc (2008) 1.26
Cardiovascular events in patients with COPD: TORCH study results. Thorax (2010) 1.25
Physical activity, health status and risk of hospitalization in patients with severe chronic obstructive pulmonary disease. Respiration (2010) 1.22
Development of the EXAcerbations of Chronic Obstructive Pulmonary Disease Tool (EXACT): a patient-reported outcome (PRO) measure. Value Health (2010) 1.21
The aging immune system and its relationship to the development of chronic obstructive pulmonary disease. Proc Am Thorac Soc (2009) 1.16
Predicting episodes of poor asthma control in treated patients with asthma. J Allergy Clin Immunol (2006) 1.16
Shotgun proteomic analysis of human-induced sputum. Proteomics (2006) 1.16
Age-related differences in clinical outcomes for acute asthma in the United States, 2006-2008. J Allergy Clin Immunol (2012) 1.16
Comparative effectiveness of noninvasive ventilation vs invasive mechanical ventilation in chronic obstructive pulmonary disease patients with acute respiratory failure. J Hosp Med (2013) 1.15
Efficacy and safety of aclidinium bromide/formoterol fumarate fixed-dose combinations compared with individual components and placebo in patients with COPD (ACLIFORM-COPD): a multicentre, randomised study. BMC Pulm Med (2014) 1.14
Pulsed moxifloxacin for the prevention of exacerbations of chronic obstructive pulmonary disease: a randomized controlled trial. Respir Res (2010) 1.14
Development and validity testing of an IPF-specific version of the St George's Respiratory Questionnaire. Thorax (2010) 1.14
Measuring the effects of COPD on the patient. Respir Med (2005) 1.13
A randomised trial of fluticasone furoate/vilanterol (50/25 μg; 100/25 μg) on lung function in COPD. Respir Med (2013) 1.12
Determinants of airflow obstruction in severe alpha-1-antitrypsin deficiency. Thorax (2007) 1.12
Regression of a plasmablastic lymphoma in a patient with HIV on highly active antiretroviral therapy. Leuk Lymphoma (2002) 1.12
The severity of airways obstruction as a determinant of treatment response in COPD. Int J Chron Obstruct Pulmon Dis (2006) 1.11
Genetics of sputum gene expression in chronic obstructive pulmonary disease. PLoS One (2011) 1.11
Noise, artifact, and oversensing related inappropriate ICD shock evaluation: ALTITUDE noise study. Pacing Clin Electrophysiol (2012) 1.09
The COPD Assessment Test (CAT): short- and medium-term response to pulmonary rehabilitation. COPD (2012) 1.09
An official American Thoracic Society Policy statement: managing conflict of interest in professional societies. Am J Respir Crit Care Med (2009) 1.09
Multicentre European study for the treatment of advanced emphysema with bronchial valves. Eur Respir J (2012) 1.09
Persistence of effectiveness of bronchial thermoplasty in patients with severe asthma. Ann Allergy Asthma Immunol (2011) 1.08