Wendy Dean

Author PubWeight™ 103.95‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency. Nature 2010 8.84
2 Epigenetic reprogramming in mammals. Hum Mol Genet 2005 6.73
3 Dynamic reprogramming of DNA methylation in the early mouse embryo. Dev Biol 2002 5.86
4 Resistance of IAPs to methylation reprogramming may provide a mechanism for epigenetic inheritance in the mouse. Genesis 2003 5.19
5 Placental-specific IGF-II is a major modulator of placental and fetal growth. Nature 2002 5.10
6 Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming. J Biol Chem 2004 4.86
7 The dynamics of genome-wide DNA methylation reprogramming in mouse primordial germ cells. Mol Cell 2012 4.32
8 Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes. PLoS Genet 2008 3.89
9 Imprinting on distal chromosome 7 in the placenta involves repressive histone methylation independent of DNA methylation. Nat Genet 2004 3.47
10 Epigenetic dynamics of stem cells and cell lineage commitment: digging Waddington's canal. Nat Rev Mol Cell Biol 2009 3.12
11 FGF signaling inhibition in ESCs drives rapid genome-wide demethylation to the epigenetic ground state of pluripotency. Cell Stem Cell 2013 2.79
12 Epigenetic restriction of embryonic cell lineage fate by methylation of Elf5. Nat Cell Biol 2008 2.77
13 Transcription is required for establishment of germline methylation marks at imprinted genes. Genes Dev 2009 2.76
14 Dynamic chromatin modifications characterise the first cell cycle in mouse embryos. Dev Biol 2005 2.51
15 Epigenetic marking correlates with developmental potential in cloned bovine preimplantation embryos. Curr Biol 2003 2.14
16 Maintenance of silent chromatin through replication requires SWI/SNF-like chromatin remodeler SMARCAD1. Mol Cell 2011 2.13
17 The imprinted signaling protein XL alpha s is required for postnatal adaptation to feeding. Nat Genet 2004 2.13
18 Regulation of supply and demand for maternal nutrients in mammals by imprinted genes. J Physiol 2003 2.01
19 Adaptation of nutrient supply to fetal demand in the mouse involves interaction between the Igf2 gene and placental transporter systems. Proc Natl Acad Sci U S A 2005 1.90
20 Conserved methylation imprints in the human and mouse GRB10 genes with divergent allelic expression suggests differential reading of the same mark. Hum Mol Genet 2003 1.80
21 Epigenetic modifications in an imprinting cluster are controlled by a hierarchy of DMRs suggesting long-range chromatin interactions. Hum Mol Genet 2003 1.73
22 Epigenetic reprogramming during early development in mammals. Reproduction 2004 1.72
23 Reprogramming DNA methylation in the mammalian life cycle: building and breaking epigenetic barriers. Philos Trans R Soc Lond B Biol Sci 2013 1.70
24 Identification of novel imprinted genes in a genome-wide screen for maternal methylation. Genome Res 2003 1.67
25 Community mental health care for women with severe mental illness who are parents. Community Ment Health J 2002 1.62
26 Gene dosage effects of the imprinted delta-like homologue 1 (dlk1/pref1) in development: implications for the evolution of imprinting. PLoS Genet 2009 1.58
27 Epigenetic properties and identification of an imprint mark in the Nesp-Gnasxl domain of the mouse Gnas imprinted locus. Mol Cell Biol 2003 1.47
28 Impaired glucose homeostasis in transgenic mice expressing the human transient neonatal diabetes mellitus locus, TNDM. J Clin Invest 2004 1.44
29 Structural differences in centromeric heterochromatin are spatially reconciled on fertilisation in the mouse zygote. Chromosoma 2007 1.33
30 Epigenetic modification is central to genome reprogramming in somatic cell nuclear transfer. Stem Cells 2005 1.33
31 Imprinted Nesp55 influences behavioral reactivity to novel environments. Mol Cell Biol 2005 1.25
32 Active demethylation in mouse zygotes involves cytosine deamination and base excision repair. Epigenetics Chromatin 2013 1.06
33 The two-domain hypothesis in Beckwith-Wiedemann syndrome: autonomous imprinting of the telomeric domain of the distal chromosome 7 cluster. Hum Mol Genet 2005 1.02
34 Disruption of mesodermal enhancers for Igf2 in the minute mutant. Development 2002 1.00
35 Evaluation of epigenetic marks in human embryos derived from IVF and ICSI. Hum Reprod 2010 0.97
36 Epigenetic asymmetry in the mammalian zygote and early embryo: relationship to lineage commitment? Philos Trans R Soc Lond B Biol Sci 2003 0.96
37 A developmental window of opportunity for imprinted gene silencing mediated by DNA methylation and the Kcnq1ot1 noncoding RNA. Mamm Genome 2007 0.95
38 Cathepsin proteases have distinct roles in trophoblast function and vascular remodelling. Development 2008 0.87
39 Paternal imprints can be established on the maternal Igf2-H19 locus without altering replication timing of DNA. Hum Mol Genet 2003 0.86
40 Using immunofluorescence to observe methylation changes in mammalian preimplantation embryos. Methods Mol Biol 2006 0.86
41 Epigenetic arbitration of cell fate decisions: tipping the bias. Dev Cell 2007 0.83
42 Regulation of lineage specific DNA hypomethylation in mouse trophectoderm. PLoS One 2013 0.81
43 Back to the beginning. Nature 2002 0.80
44 The elusive Dnmt1 and its role during early development. Epigenetics 2008 0.76
45 Nucleus replacement in Mammalian oocytes. Cloning Stem Cells 2002 0.75
46 Gene expression: Silent clones speak up. Nature 2003 0.75
47 Transitioning trauma research: Navigating the regulatory requirements for medical product development. J Trauma Acute Care Surg 2016 0.75