Closing the door on flaviviruses: entry as a target for antiviral drug design.

PubWeight™: 1.09‹?› | Rank: Top 10%

🔗 View Article (PMC 2646114)

Published in Antiviral Res on June 11, 2008

Authors

Rushika Perera1, Mansoora Khaliq, Richard J Kuhn

Author Affiliations

1: Markey Center for Structural Biology and Department of Biological Sciences, Purdue University, West Lafayette, IN 47907, USA.

Articles citing this

Molecular targets for flavivirus drug discovery. Antiviral Res (2008) 2.32

The human antibody response to dengue virus infection. Viruses (2011) 1.79

Flaviviruses: braking the entering. Curr Opin Virol (2013) 1.02

A small animal peripheral challenge model of yellow fever using interferon-receptor deficient mice and the 17D-204 vaccine strain. Vaccine (2012) 1.00

Mechanism and significance of cell type-dependent neutralization of flaviviruses. J Virol (2014) 0.98

Focus on flaviviruses: current and future drug targets. Future Med Chem (2009) 0.94

West Nile virus: A re-emerging pathogen revisited. World J Virol (2012) 0.94

Role of microparticles in dengue virus infection and its impact on medical intervention strategies. Yale J Biol Med (2012) 0.87

An analogue of the antibiotic teicoplanin prevents flavivirus entry in vitro. PLoS One (2012) 0.86

Differential requirements in endocytic trafficking for penetration of dengue virus. PLoS One (2012) 0.86

Japanese encephalitis virus infects porcine kidney epithelial PK15 cells via clathrin- and cholesterol-dependent endocytosis. Virol J (2013) 0.86

Dengue virus entry as target for antiviral therapy. J Trop Med (2012) 0.86

Probing the mechanism of pH-induced large-scale conformational changes in dengue virus envelope protein using atomistic simulations. Biophys J (2010) 0.83

West Nile virus drug discovery. Viruses (2013) 0.82

Dengue Fever: Causes, Complications, and Vaccine Strategies. J Immunol Res (2016) 0.82

Dengue-3 Virus Entry into Vero Cells: Role of Clathrin-Mediated Endocytosis in the Outcome of Infection. PLoS One (2015) 0.80

Prediction of protein-protein interactions in dengue virus coat proteins guided by low resolution cryoEM structures. BMC Struct Biol (2010) 0.79

Towards peptide vaccines against Zika virus: Immunoinformatics combined with molecular dynamics simulations to predict antigenic epitopes of Zika viral proteins. Sci Rep (2016) 0.77

New pockets in dengue virus 2 surface identified by molecular dynamics simulation. J Mol Model (2012) 0.76

Serial femtosecond X-ray diffraction of enveloped virus microcrystals. Struct Dyn (2015) 0.76

DENV up-regulates the HMG-CoA reductase activity through the impairment of AMPK phosphorylation: A potential antiviral target. PLoS Pathog (2017) 0.75

Frog skin cultures secrete anti-yellow fever compounds. J Antibiot (Tokyo) (2016) 0.75

Inhibitors compounds of the flavivirus replication process. Virol J (2017) 0.75

Complexity of Human Antibody Response to Dengue Virus: Implication for Vaccine Development. Front Microbiol (2017) 0.75

High-speed fixed-target serial virus crystallography. Nat Methods (2017) 0.75

Articles cited by this

(truncated to the top 100)

Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin. Annu Rev Biochem (2000) 19.03

Structure of a human common cold virus and functional relationship to other picornaviruses. Nature (1985) 12.90

The envelope glycoprotein from tick-borne encephalitis virus at 2 A resolution. Nature (1995) 12.25

Structure of dengue virus: implications for flavivirus organization, maturation, and fusion. Cell (2002) 9.13

Mechanisms of viral membrane fusion and its inhibition. Annu Rev Biochem (2001) 8.96

Structure of the dengue virus envelope protein after membrane fusion. Nature (2004) 7.97

A ligand-binding pocket in the dengue virus envelope glycoprotein. Proc Natl Acad Sci U S A (2003) 7.76

Dengue virus infectivity depends on envelope protein binding to target cell heparan sulfate. Nat Med (1997) 6.57

Development of a humanized monoclonal antibody with therapeutic potential against West Nile virus. Nat Med (2005) 5.09

A structural perspective of the flavivirus life cycle. Nat Rev Microbiol (2005) 5.02

DC-SIGN (CD209) mediates dengue virus infection of human dendritic cells. J Exp Med (2003) 4.69

The site of attachment in human rhinovirus 14 for antiviral agents that inhibit uncoating. Science (1986) 4.40

Monoclonal antibodies that bind to domain III of dengue virus E glycoprotein are the most efficient blockers of virus adsorption to Vero cells. J Virol (2001) 4.27

The many mechanisms of viral membrane fusion proteins. Curr Top Microbiol Immunol (2005) 4.19

Visualization of membrane protein domains by cryo-electron microscopy of dengue virus. Nat Struct Biol (2003) 4.11

Structure of a flavivirus envelope glycoprotein in its low-pH-induced membrane fusion conformation. EMBO J (2004) 4.05

In vivo enhancement of dengue virus infection in rhesus monkeys by passively transferred antibody. J Infect Dis (1979) 3.90

Structure of the immature dengue virus at low pH primes proteolytic maturation. Science (2008) 3.86

Monoclonal antibody mapping of the envelope glycoprotein of the dengue 2 virus, Jamaica. Virology (1998) 3.80

Proteolytic activation of tick-borne encephalitis virus by furin. J Virol (1997) 3.78

Membrane fusion machines of paramyxoviruses: capture of intermediates of fusion. EMBO J (2001) 3.76

Oligomeric rearrangement of tick-borne encephalitis virus envelope proteins induced by an acidic pH. J Virol (1995) 3.67

Conformational changes of the flavivirus E glycoprotein. Structure (2004) 3.66

Structures of immature flavivirus particles. EMBO J (2003) 3.62

Variable surface epitopes in the crystal structure of dengue virus type 3 envelope glycoprotein. J Virol (2005) 3.58

Mutational evidence for an internal fusion peptide in flavivirus envelope protein E. J Virol (2001) 3.58

Antibody, macrophages, dengue virus infection, shock, and hemorrhage: a pathogenetic cascade. Rev Infect Dis (1989) 3.53

Structural basis of West Nile virus neutralization by a therapeutic antibody. Nature (2005) 3.51

Structure of West Nile virus. Science (2003) 3.48

Pathogenic flaviviruses. Lancet (2008) 3.34

Dendritic-cell-specific ICAM3-grabbing non-integrin is essential for the productive infection of human dendritic cells by mosquito-cell-derived dengue viruses. EMBO Rep (2003) 3.29

Mutations that alter an Arg-Gly-Asp (RGD) sequence in the adenovirus type 2 penton base protein abolish its cell-rounding activity and delay virus reproduction in flat cells. J Virol (1993) 3.29

Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins. Nat Struct Mol Biol (2008) 3.27

The flavivirus precursor membrane-envelope protein complex: structure and maturation. Science (2008) 3.26

The stoichiometry of antibody-mediated neutralization and enhancement of West Nile virus infection. Cell Host Microbe (2007) 3.25

Antibody recognition and neutralization determinants on domains I and II of West Nile Virus envelope protein. J Virol (2006) 3.23

Molecular organization of a recombinant subviral particle from tick-borne encephalitis virus. Mol Cell (2001) 3.23

New mouse model for dengue virus vaccine testing. J Virol (1999) 3.18

A West Nile virus DNA vaccine induces neutralizing antibody in healthy adults during a phase 1 clinical trial. J Infect Dis (2007) 3.02

Type- and subcomplex-specific neutralizing antibodies against domain III of dengue virus type 2 envelope protein recognize adjacent epitopes. J Virol (2007) 2.89

A critical role for induced IgM in the protection against West Nile virus infection. J Exp Med (2003) 2.89

Mapping of functional elements in the stem-anchor region of tick-borne encephalitis virus envelope protein E. J Virol (1999) 2.87

West Nile virus discriminates between DC-SIGN and DC-SIGNR for cellular attachment and infection. J Virol (2006) 2.79

Antiviral agent blocks breathing of the common cold virus. Proc Natl Acad Sci U S A (1998) 2.71

Prevention of rhinovirus and poliovirus uncoating by WIN 51711, a new antiviral drug. Antimicrob Agents Chemother (1986) 2.70

Identification of neutralizing epitopes within structural domain III of the West Nile virus envelope protein. J Virol (2002) 2.66

Localization and characterization of flavivirus envelope glycoprotein cross-reactive epitopes. J Virol (2004) 2.64

Conformational change in the floor of the human rhinovirus canyon blocks adsorption to HeLa cell receptors. J Virol (1989) 2.61

Crystal structure of the West Nile virus envelope glycoprotein. J Virol (2006) 2.61

The energetics of membrane fusion from binding, through hemifusion, pore formation, and pore enlargement. J Membr Biol (2004) 2.59

Biophysical characterization and vector-specific antagonist activity of domain III of the tick-borne flavivirus envelope protein. J Virol (2001) 2.59

The Murray Valley encephalitis virus prM protein confers acid resistance to virus particles and alters the expression of epitopes within the R2 domain of E glycoprotein. Virology (1992) 2.48

Fusion activity of flaviviruses: comparison of mature and immature (prM-containing) tick-borne encephalitis virions. J Gen Virol (1991) 2.34

Structural requirements for low-pH-induced rearrangements in the envelope glycoprotein of tick-borne encephalitis virus. J Virol (1996) 2.33

Cryptic properties of a cluster of dominant flavivirus cross-reactive antigenic sites. J Virol (2006) 2.33

Structural analysis of a series of antiviral agents complexed with human rhinovirus 14. Proc Natl Acad Sci U S A (1988) 2.30

Analysis of the steps involved in Dengue virus entry into host cells. Virology (1999) 2.22

Crystal structure of west nile virus envelope glycoprotein reveals viral surface epitopes. J Virol (2006) 2.20

Antigenic structure of flavivirus proteins. Adv Virus Res (2003) 2.15

Antibody prophylaxis and therapy for flavivirus encephalitis infections. Ann N Y Acad Sci (2001) 2.13

Rab 5 is required for the cellular entry of dengue and West Nile viruses. J Virol (2007) 2.12

The mannose receptor mediates dengue virus infection of macrophages. PLoS Pathog (2008) 2.09

Membrane fusion activity of tick-borne encephalitis virus and recombinant subviral particles in a liposomal model system. Virology (2000) 2.09

Cryo-EM reconstruction of dengue virus in complex with the carbohydrate recognition domain of DC-SIGN. Cell (2006) 2.08

Monoclonal antibodies against dengue 2 virus E-glycoprotein protect mice against lethal dengue infection. Am J Trop Med Hyg (1987) 2.07

West Nile virus core protein; tetramer structure and ribbon formation. Structure (2004) 2.04

Mechanism of membrane fusion by viral envelope proteins. Adv Virus Res (2005) 2.04

Characterization of the early events in dengue virus cell entry by biochemical assays and single-virus tracking. J Virol (2007) 2.03

Dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN)-mediated enhancement of dengue virus infection is independent of DC-SIGN internalization signals. J Biol Chem (2005) 2.02

Adaptation of tick-borne encephalitis virus to BHK-21 cells results in the formation of multiple heparan sulfate binding sites in the envelope protein and attenuation in vivo. J Virol (2001) 1.94

Evidence of viral capsid dynamics using limited proteolysis and mass spectrometry. J Biol Chem (1998) 1.94

Viral cell recognition and entry. Protein Sci (1994) 1.93

Genetic and molecular analyses of spontaneous mutants of human rhinovirus 14 that are resistant to an antiviral compound. J Virol (1989) 1.92

RGD-dependent entry of coxsackievirus A9 into host cells and its bypass after cleavage of VP1 protein by intestinal proteases. J Virol (1991) 1.91

Cleavage of protein prM is necessary for infection of BHK-21 cells by tick-borne encephalitis virus. J Gen Virol (2003) 1.90

Domain III from class II fusion proteins functions as a dominant-negative inhibitor of virus membrane fusion. J Cell Biol (2005) 1.88

Inhibition of West Nile virus entry by using a recombinant domain III from the envelope glycoprotein. J Gen Virol (2005) 1.86

Differences between cell membrane fusion activities of two dengue type-1 isolates reflect modifications of viral structure. Virology (1993) 1.86

Identification of GRP 78 (BiP) as a liver cell expressed receptor element for dengue virus serotype 2. Arch Virol (2004) 1.85

Solution structure of dengue virus capsid protein reveals another fold. Proc Natl Acad Sci U S A (2004) 1.85

Membrane interactions of the tick-borne encephalitis virus fusion protein E at low pH. J Virol (2002) 1.83

West Nile virus in complex with the Fab fragment of a neutralizing monoclonal antibody. Proc Natl Acad Sci U S A (2006) 1.83

Characterization of neutralizing antibodies to West Nile virus. Virology (2005) 1.81

The flavivirus envelope protein E: isolation of a soluble form from tick-borne encephalitis virus and its crystallization. J Virol (1991) 1.80

The machinery for flavivirus fusion with host cell membranes. Curr Opin Microbiol (2001) 1.77

Structure of immature West Nile virus. J Virol (2007) 1.77

HIV entry inhibitors. Lancet (2007) 1.73

A live, attenuated recombinant West Nile virus vaccine. Proc Natl Acad Sci U S A (2006) 1.72

Live attenuated yellow fever 17D infects human DCs and allows for presentation of endogenous and recombinant T cell epitopes. J Exp Med (2005) 1.71

Localization of a neutralizing epitope on the envelope protein of dengue virus type 2. Virology (1994) 1.67

Construction and applications of yellow fever virus replicons. Virology (2005) 1.66

Enhancement of dengue virus infection in monocytes by flavivirus antisera. Am J Trop Med Hyg (1980) 1.65

Circular ribosomal DNA plasmids transform Tetrahymena thermophila by homologous recombination with endogenous macronuclear ribosomal DNA. Proc Natl Acad Sci U S A (1988) 1.63

Substitutions at the putative receptor-binding site of an encephalitic flavivirus alter virulence and host cell tropism and reveal a role for glycosaminoglycans in entry. J Virol (2000) 1.62

Epitope determinants of a chimpanzee Fab antibody that efficiently cross-neutralizes dengue type 1 and type 2 viruses map to inside and in close proximity to fusion loop of the dengue type 2 virus envelope glycoprotein. J Virol (2004) 1.58

Elucidation of the topography and determination of the protective epitopes on the E glycoprotein of Saint Louis encephalitis virus by passive transfer with monoclonal antibodies. J Immunol (1984) 1.58

Monoclonal antibodies for dengue virus prM glycoprotein protect mice against lethal dengue infection. Am J Trop Med Hyg (1989) 1.57

Selection and partial characterization of dengue 2 virus mutants that induce fusion at elevated pH. Virology (1993) 1.56

Interaction of West Nile virus with alpha v beta 3 integrin mediates virus entry into cells. J Biol Chem (2004) 1.56

Virology: a class act. Nature (2004) 1.54

Articles by these authors

A structural perspective of the flavivirus life cycle. Nat Rev Microbiol (2005) 5.02

Visualization of membrane protein domains by cryo-electron microscopy of dengue virus. Nat Struct Biol (2003) 4.11

Structure of the immature dengue virus at low pH primes proteolytic maturation. Science (2008) 3.86

Conformational changes of the flavivirus E glycoprotein. Structure (2004) 3.66

Structures of immature flavivirus particles. EMBO J (2003) 3.62

Structure of West Nile virus. Science (2003) 3.48

Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins. Nat Struct Mol Biol (2008) 3.27

The flavivirus precursor membrane-envelope protein complex: structure and maturation. Science (2008) 3.26

Dengue virus nonstructural protein 3 redistributes fatty acid synthase to sites of viral replication and increases cellular fatty acid synthesis. Proc Natl Acad Sci U S A (2010) 2.97

Placement of the structural proteins in Sindbis virus. J Virol (2002) 2.81

Structural changes of envelope proteins during alphavirus fusion. Nature (2010) 2.32

Picornavirus-receptor interactions. Trends Microbiol (2002) 2.23

Flavivirus NS1 structures reveal surfaces for associations with membranes and the immune system. Science (2014) 2.16

Structural insights into the mechanisms of antibody-mediated neutralization of flavivirus infection: implications for vaccine development. Cell Host Microbe (2008) 2.16

Cryo-EM reconstruction of dengue virus in complex with the carbohydrate recognition domain of DC-SIGN. Cell (2006) 2.08

The structure of the RNA-dependent RNA polymerase from bovine viral diarrhea virus establishes the role of GTP in de novo initiation. Proc Natl Acad Sci U S A (2004) 2.05

Characterization of the early events in dengue virus cell entry by biochemical assays and single-virus tracking. J Virol (2007) 2.03

Structural basis for the preferential recognition of immature flaviviruses by a fusion-loop antibody. EMBO J (2009) 1.85

Solution structure of dengue virus capsid protein reveals another fold. Proc Natl Acad Sci U S A (2004) 1.85

West Nile virus in complex with the Fab fragment of a neutralizing monoclonal antibody. Proc Natl Acad Sci U S A (2006) 1.83

The crystal structure of coxsackievirus A21 and its interaction with ICAM-1. Structure (2005) 1.82

Crystal structure of human enterovirus 71. Science (2012) 1.79

Structure of immature West Nile virus. J Virol (2007) 1.77

Dengue structure differs at the temperatures of its human and mosquito hosts. Proc Natl Acad Sci U S A (2013) 1.75

A structural and functional perspective of alphavirus replication and assembly. Future Microbiol (2009) 1.72

Mapping the structure and function of the E1 and E2 glycoproteins in alphaviruses. Structure (2006) 1.68

Construction and applications of yellow fever virus replicons. Virology (2005) 1.66

Structure of the Flavivirus helicase: implications for catalytic activity, protein interactions, and proteolytic processing. J Virol (2005) 1.65

Yellow Fever virus NS3 plays an essential role in virus assembly independent of its known enzymatic functions. J Virol (2008) 1.59

Structural proteomics of dengue virus. Curr Opin Microbiol (2008) 1.57

Neutralization of West Nile virus by cross-linking of its surface proteins with Fab fragments of the human monoclonal antibody CR4354. Proc Natl Acad Sci U S A (2010) 1.57

Structure-guided insights on the role of NS1 in flavivirus infection. Bioessays (2015) 1.46

Dengue virus infection perturbs lipid homeostasis in infected mosquito cells. PLoS Pathog (2012) 1.45

Flavivirus capsid is a dimeric alpha-helical protein. J Virol (2003) 1.43

Influence of pr-M cleavage on the heterogeneity of extracellular dengue virus particles. J Virol (2010) 1.41

Complexes of poliovirus serotypes with their common cellular receptor, CD155. J Virol (2003) 1.31

Maturation of flaviviruses starts from one or more icosahedrally independent nucleation centres. EMBO Rep (2011) 1.31

Ultrastructural analysis of hepatitis C virus particles. Proc Natl Acad Sci U S A (2013) 1.29

Design, synthesis, and biological evaluation of antiviral agents targeting flavivirus envelope proteins. J Med Chem (2008) 1.28

Functional characterization of cis and trans activity of the Flavivirus NS2B-NS3 protease. J Biol Chem (2007) 1.25

Capturing a flavivirus pre-fusion intermediate. PLoS Pathog (2009) 1.24

Heparin binding sites on Ross River virus revealed by electron cryo-microscopy. Virology (2005) 1.18

Ultrastructural characterization and three-dimensional architecture of replication sites in dengue virus-infected mosquito cells. J Virol (2014) 1.17

Structure of decay-accelerating factor bound to echovirus 7: a virus-receptor complex. Proc Natl Acad Sci U S A (2002) 1.17

Catalytic core of alphavirus nonstructural protein nsP4 possesses terminal adenylyltransferase activity. J Virol (2006) 1.13

Antiviral compounds discovered by virtual screening of small-molecule libraries against dengue virus E protein. ACS Chem Biol (2008) 1.06

In vitro-assembled alphavirus core-like particles maintain a structure similar to that of nucleocapsid cores in mature virus. J Virol (2002) 1.06

Characterization of purified Sindbis virus nsP4 RNA-dependent RNA polymerase activity in vitro. Virology (2008) 1.05

The coiled-coil domain structure of the Sin Nombre virus nucleocapsid protein. J Mol Biol (2006) 1.04

A physical interaction network of dengue virus and human proteins. Mol Cell Proteomics (2011) 1.03

Alphavirus capsid protein helix I controls a checkpoint in nucleocapsid core assembly. J Virol (2006) 1.01

Aura virus structure suggests that the T=4 organization is a fundamental property of viral structural proteins. J Virol (2002) 1.00

Role of sindbis virus capsid protein region II in nucleocapsid core assembly and encapsidation of genomic RNA. J Virol (2008) 0.98

Structure of human enterovirus 71 in complex with a capsid-binding inhibitor. Proc Natl Acad Sci U S A (2013) 0.98

Molecular links between the E2 envelope glycoprotein and nucleocapsid core in Sindbis virus. J Mol Biol (2011) 0.98

A heterologous coiled coil can substitute for helix I of the Sindbis virus capsid protein. J Virol (2003) 0.98

Role for conserved residues of sindbis virus nonstructural protein 2 methyltransferase-like domain in regulation of minus-strand synthesis and development of cytopathic infection. J Virol (2008) 0.96

Functional requirements of the yellow fever virus capsid protein. J Virol (2007) 0.96

Sindbis virus nucleocapsid assembly: RNA folding promotes capsid protein dimerization. RNA (2004) 0.95

Association of sindbis virus capsid protein with phospholipid membranes and the E2 glycoprotein: implications for alphavirus assembly. Biochemistry (2005) 0.93

An investigation of phenylthiazole antiflaviviral agents. Bioorg Med Chem (2011) 0.92

Cryo-electron tomography of rubella virus. J Virol (2012) 0.92

Interactions of the cytoplasmic domain of Sindbis virus E2 with nucleocapsid cores promote alphavirus budding. J Virol (2011) 0.90

Identification of inhibitors of yellow fever virus replication using a replicon-based high-throughput assay. Antimicrob Agents Chemother (2009) 0.88

Rescue of infectious particles from preassembled alphavirus nucleocapsid cores. J Virol (2011) 0.87

Functional characterization of the alphavirus TF protein. J Virol (2013) 0.86

Design, synthesis, and biological evaluation of thiazoles targeting flavivirus envelope proteins. J Med Chem (2011) 0.86

Structure determination of enterovirus 71. Acta Crystallogr D Biol Crystallogr (2012) 0.86

Capturing a virus while it catches its breath. Structure (2012) 0.85

Neutralizing antibodies can initiate genome release from human enterovirus 71. Proc Natl Acad Sci U S A (2014) 0.85

Directed evolution of a virus exclusively utilizing human epidermal growth factor receptor as the entry receptor. J Virol (2013) 0.84

Functional characterization of the Sindbis virus E2 glycoprotein by transposon linker-insertion mutagenesis. Virology (2007) 0.83

Heterologous production, purification and characterization of enzymatically active Sindbis virus nonstructural protein nsP1. Protein Expr Purif (2011) 0.83

Novel approaches to flavivirus drug discovery. Expert Opin Drug Discov (2012) 0.83

Synthesis of dioxane-based antiviral agents and evaluation of their biological activities as inhibitors of Sindbis virus replication. Bioorg Med Chem (2007) 0.82

Membrane curvature in flaviviruses. J Struct Biol (2013) 0.82

Reactive oxygen species formation by UV-A irradiation of urocanic acid and the role of trace metals in this chemistry. Photochem Photobiol (2003) 0.81

Design, expression, and purification of a Flaviviridae polymerase using a high-throughput approach to facilitate crystal structure determination. Protein Sci (2004) 0.80

Crystallization, high-resolution data collection and preliminary crystallographic analysis of Aura virus capsid protease and its complex with dioxane. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.79

West Nile virus methyltransferase domain interacts with protein kinase G. Virol J (2013) 0.79

Probing the early temporal and spatial interaction of the Sindbis virus capsid and E2 proteins with reverse genetics. J Virol (2012) 0.78

Crystal structure of aura virus capsid protease and its complex with dioxane: new insights into capsid-glycoprotein molecular contacts. PLoS One (2012) 0.78

Rapid detection of dengue virus in serum using magnetic separation and fluorescence detection. Analyst (2007) 0.77

Crystallization and preliminary X-ray diffraction analysis of West Nile virus. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.77

Phototoxicity against tumor cells and Sindbis virus by an octahedral rhodium bisbipyridyl complex and evidence for the genome as a target in viral photoinactivation. Inorg Chem (2004) 0.75

Development of novel antivirals against flaviviruses. Novartis Found Symp (2006) 0.75