Published in Cancer Res on July 01, 2008
T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus. Proc Natl Acad Sci U S A (2008) 4.74
Merkel cell polyomavirus-infected Merkel cell carcinoma cells require expression of viral T antigens. J Virol (2010) 2.88
Human Merkel cell polyomavirus infection II. MCV is a common human infection that can be detected by conformational capsid epitope immunoassays. Int J Cancer (2009) 2.77
Transcriptome-wide studies of merkel cell carcinoma and validation of intratumoral CD8+ lymphocyte invasion as an independent predictor of survival. J Clin Oncol (2011) 2.52
The role of polyomaviruses in human disease. Virology (2008) 2.41
Human Merkel cell polyomavirus small T antigen is an oncoprotein targeting the 4E-BP1 translation regulator. J Clin Invest (2011) 2.37
Association of Merkel cell polyomavirus-specific antibodies with Merkel cell carcinoma. J Natl Cancer Inst (2009) 2.22
Antibodies to merkel cell polyomavirus T antigen oncoproteins reflect tumor burden in merkel cell carcinoma patients. Cancer Res (2010) 2.14
Quantitation of human seroresponsiveness to Merkel cell polyomavirus. PLoS Pathog (2009) 2.08
Merkel cell polyomavirus expression in merkel cell carcinomas and its absence in combined tumors and pulmonary neuroendocrine carcinomas. Am J Surg Pathol (2009) 1.79
Improved detection suggests all Merkel cell carcinomas harbor Merkel polyomavirus. J Clin Invest (2012) 1.61
Quantitative detection of Merkel cell virus in human tissues and possible mode of transmission. Int J Cancer (2010) 1.53
The minimum replication origin of merkel cell polyomavirus has a unique large T-antigen loading architecture and requires small T-antigen expression for optimal replication. J Virol (2009) 1.52
Merkel cell carcinoma: a virus-induced human cancer. Annu Rev Pathol (2011) 1.46
Merkel cell polyomavirus DNA in persons without merkel cell carcinoma. Emerg Infect Dis (2009) 1.45
Activation of PI3K signaling in Merkel cell carcinoma. Clin Cancer Res (2012) 1.45
Merkel cell carcinoma subgroups by Merkel cell polyomavirus DNA relative abundance and oncogene expression. Int J Cancer (2010) 1.42
Detection of Merkel cell polyomavirus with a tumour-specific signature in non-small cell lung cancer. Br J Cancer (2013) 1.41
Distinct merkel cell polyomavirus molecular features in tumour and non tumour specimens from patients with merkel cell carcinoma. PLoS Pathog (2010) 1.40
Age-specific seroprevalence of Merkel cell polyomavirus, BK virus, and JC virus. Clin Vaccine Immunol (2011) 1.35
Merkel cell carcinoma: recent progress and current priorities on etiology, pathogenesis, and clinical management. J Clin Oncol (2009) 1.28
Merkel cell polyomavirus large T antigen disrupts host genomic integrity and inhibits cellular proliferation. J Virol (2013) 1.28
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Chronic lymphocytic leukaemia patients have a high risk of Merkel-cell polyomavirus DNA-positive Merkel-cell carcinoma. Br J Cancer (2009) 1.26
Hybrid capture and next-generation sequencing identify viral integration sites from formalin-fixed, paraffin-embedded tissue. J Mol Diagn (2011) 1.26
Seroprevalence of trichodysplasia spinulosa-associated polyomavirus. Emerg Infect Dis (2011) 1.25
Merkel cell polyomavirus in cutaneous swabs. Emerg Infect Dis (2010) 1.25
Cellular and viral factors regulating Merkel cell polyomavirus replication. PLoS One (2011) 1.21
Distinct gene expression profiles of viral- and nonviral-associated merkel cell carcinoma revealed by transcriptome analysis. J Invest Dermatol (2012) 1.14
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Microbial ecology of the skin in the era of metagenomics and molecular microbiology. Cold Spring Harb Perspect Med (2013) 1.07
Merkel cell polyomavirus strains in patients with merkel cell carcinoma. Emerg Infect Dis (2009) 1.05
Ultrastructural proof of polyomavirus in Merkel cell carcinoma tumour cells and its absence in small cell carcinoma of the lung. PLoS One (2009) 1.04
Immunological detection of viral large T antigen identifies a subset of Merkel cell carcinoma tumors with higher viral abundance and better clinical outcome. Int J Cancer (2010) 1.03
Immunobiology of Merkel cell carcinoma: implications for immunotherapy of a polyomavirus-associated cancer. Curr Oncol Rep (2011) 1.03
Getting stronger: the relationship between a newly identified virus and Merkel cell carcinoma. J Invest Dermatol (2009) 1.01
Asymptomatic primary Merkel cell polyomavirus infection among adults. Emerg Infect Dis (2011) 0.99
Structural evaluation of new human polyomaviruses provides clues to pathobiology. Trends Microbiol (2010) 0.98
Replication, gene expression and particle production by a consensus Merkel Cell Polyomavirus (MCPyV) genome. PLoS One (2011) 0.98
Human polyomaviruses in skin diseases. Patholog Res Int (2011) 0.98
A comparative study of Merkel cell, BK and JC polyomavirus infections in renal transplant recipients and healthy subjects. J Clin Virol (2010) 0.98
A phase II trial of imatinib mesylate in merkel cell carcinoma (neuroendocrine carcinoma of the skin): A Southwest Oncology Group study (S0331). Am J Clin Oncol (2010) 0.96
Characterization of an early passage Merkel cell polyomavirus-positive Merkel cell carcinoma cell line, MS-1, and its growth in NOD scid gamma mice. J Virol Methods (2012) 0.96
Histological, immunohistological, and clinical features of merkel cell carcinoma in correlation to merkel cell polyomavirus status. J Skin Cancer (2012) 0.96
Chronic mTOR activation promotes cell survival in Merkel cell carcinoma. Cancer Lett (2013) 0.94
Nuclear IRS-1 and cancer. J Cell Physiol (2012) 0.94
Lymphotropism of Merkel cell polyomavirus infection, Nova Scotia, Canada. Emerg Infect Dis (2010) 0.93
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Merkel cell polyomavirus in Merkel cell carcinoma of Italian patients. Virol J (2011) 0.91
Merkel cell polyomavirus small T antigen mRNA level is increased following in vivo UV-radiation. PLoS One (2010) 0.90
Restricted protein phosphatase 2A targeting by Merkel cell polyomavirus small T antigen. J Virol (2015) 0.89
High-affinity Rb binding, p53 inhibition, subcellular localization, and transformation by wild-type or tumor-derived shortened Merkel cell polyomavirus large T antigens. J Virol (2013) 0.89
T-helper cell-mediated proliferation and cytokine responses against recombinant Merkel cell polyomavirus-like particles. PLoS One (2011) 0.88
Physical and functional interaction between polyoma virus middle T antigen and insulin and IGF-I receptors is required for oncogene activation and tumour initiation. Oncogene (2009) 0.87
Merkel cell polyomavirus: molecular insights into the most recently discovered human tumour virus. Cancers (Basel) (2014) 0.87
A specific signature of Merkel cell polyomavirus persistence in human cancer cells. Proc Natl Acad Sci U S A (2008) 0.86
Detection of Merkel cell virus and correlation with histologic presence of Merkel cell carcinoma in sentinel lymph nodes. Br J Cancer (2012) 0.86
Merkel cell carcinoma in immunosuppressed patients. Cancers (Basel) (2014) 0.86
Therapeutic options for treatment of Merkel cell carcinoma. Eur Arch Otorhinolaryngol (2010) 0.85
Detection of Merkel cell polyomavirus in cervical squamous cell carcinomas and adenocarcinomas from Japanese patients. Virol J (2012) 0.85
Merkel Cell Polyomavirus Small T Antigen Induces Cancer and Embryonic Merkel Cell Proliferation in a Transgenic Mouse Model. PLoS One (2015) 0.84
Newly discovered KI, WU, and Merkel cell polyomaviruses: no evidence of mother-to-fetus transmission. Virol J (2010) 0.84
Detection of human polyomavirus 7 in human thymic epithelial tumors. J Thorac Oncol (2015) 0.84
Frequent detection of Merkel cell polyomavirus DNA in sera of HIV-1-positive patients. Virol J (2013) 0.84
Merkel cell polyomavirus is not detected in mesotheliomas. J Clin Virol (2009) 0.83
Merkel cell carcinoma. Am J Clin Oncol (2013) 0.83
Aberrant Promoter Hypermethylation of RASSF Family Members in Merkel Cell Carcinoma. Cancers (Basel) (2013) 0.83
Merkel Cell Polyomavirus Exhibits Dominant Control of the Tumor Genome and Transcriptome in Virus-Associated Merkel Cell Carcinoma. MBio (2017) 0.81
Merkel cell polyomavirus is frequently detected in korean patients with merkel cell carcinoma. Ann Dermatol (2013) 0.81
Risk of second cancers after the diagnosis of Merkel cell carcinoma in Scandinavia. Br J Cancer (2010) 0.81
Gastric metastasis of Merkel cell carcinoma, a rare cause of gastrointestinal bleeding: case report and review of the literature. J Gastrointest Oncol (2014) 0.80
Polyomaviruses and disease: is there more to know than viremia and viruria? Curr Opin Organ Transplant (2015) 0.80
Bcl-2 expression indicates better prognosis of Merkel cell carcinoma regardless of the presence of Merkel cell polyomavirus. Virchows Arch (2012) 0.79
Quantitative analysis of viral load per haploid genome revealed the different biological features of Merkel cell polyomavirus infection in skin tumor. PLoS One (2012) 0.79
Frequent detection of human polyomavirus 6 in keratoacanthomas. Diagn Pathol (2016) 0.79
Creation of a Merkel cell polyomavirus small T antigen-expressing murine tumor model and a DNA vaccine targeting small T antigen. Cell Biosci (2013) 0.78
Characterization of self-assembled virus-like particles of Merkel cell polyomavirus. PLoS One (2015) 0.78
Interaction of human tumor viruses with host cell surface receptors and cell entry. Viruses (2015) 0.78
RB1 is the crucial target of the Merkel cell polyomavirus Large T antigen in Merkel cell carcinoma cells. Oncotarget (2016) 0.78
Radiotherapy is associated with significant improvement in local and regional control in Merkel cell carcinoma. Radiat Oncol (2012) 0.77
[Merkel cell polyomavirus in the pathogenesis of non-melanoma skin cancer]. Pathologe (2009) 0.77
Polyomavirus-negative Merkel cell carcinoma: a more aggressive subtype based on analysis of 282 cases using multi-modal tumor virus detection. J Invest Dermatol (2016) 0.77
Phosphorylation of Merkel cell polyomavirus large tumor antigen at serine 816 by ATM kinase induces apoptosis in host cells. J Biol Chem (2014) 0.76
Suppression of immunodominant antitumor and antiviral CD8+ T cell responses by indoleamine 2,3-dioxygenase. PLoS One (2014) 0.75
Primary Merkel Cell Carcinoma of the Submandibular Gland: When CK20 Status Complicates the Diagnosis. Head Neck Pathol (2014) 0.75
Merkel cell carcinoma with partial B-cell blastic immunophenotype: a potential mimic of cutaneous richter transformation in a patient with chronic lymphocytic lymphoma. Am J Dermatopathol (2014) 0.75
Merkel cell carcinoma of unknown primary with lymph node and mesenteric metastasis involving the pancreas and duodenum. J Gastrointest Oncol (2016) 0.75
No evidence for WU polyomavirus infection in chronic obstructive pulmonary disease. Infect Agent Cancer (2009) 0.75
Metastatic Merkel cell carcinoma in the bone marrow of a patient with plasma cell myeloma and therapy-related myelodysplastic syndrome. Int J Clin Exp Pathol (2012) 0.75
Prevalence of Merkel Cell Polyomavirus in Tehran: An Age-Specific Serological Study. Iran Red Crescent Med J (2016) 0.75
Do erythropoietin receptors on cancer cells explain unexpected clinical findings? J Clin Oncol (2006) 5.56
Aurora kinase A messenger RNA overexpression is correlated with tumor progression and shortened survival in head and neck squamous cell carcinoma. Clin Cancer Res (2006) 2.88
Prediction of response to neoadjuvant chemotherapy by sequential F-18-fluorodeoxyglucose positron emission tomography in patients with advanced-stage ovarian cancer. J Clin Oncol (2005) 2.54
HER2 status of circulating tumor cells in patients with metastatic breast cancer: a prospective, multicenter trial. Breast Cancer Res Treat (2010) 2.12
First experience with drug-eluting balloons in infrapopliteal arteries: restenosis rate and clinical outcome. J Am Coll Cardiol (2011) 1.78
ERCP or EUS for tissue diagnosis of biliary strictures? A prospective comparative study. Gastrointest Endosc (2004) 1.73
Detection of a novel truncating Merkel cell polyomavirus large T antigen deletion in chronic lymphocytic leukemia cells. Blood (2010) 1.73
The role of Epstein-Barr virus in acute and chronic hepatitis. J Hepatol (2006) 1.69
Array CGH identifies distinct DNA copy number profiles of oncogenes and tumor suppressor genes in chromosomal- and microsatellite-unstable sporadic colorectal carcinomas. J Mol Med (Berl) (2006) 1.69
Retrograde recanalization technique for use after failed antegrade angioplasty in chronic femoral artery occlusions. J Endovasc Ther (2012) 1.64
Synchronicity of Antarctic temperatures and local solar insolation on orbital timescales. Nature (2011) 1.63
European Registry of Carotid Artery Stenting: results from a prospective registry of eight high volume EUROPEAN institutions. Catheter Cardiovasc Interv (2012) 1.61
Impact of treatment characteristics on response of different breast cancer phenotypes: pooled analysis of the German neo-adjuvant chemotherapy trials. Breast Cancer Res Treat (2010) 1.60
Pigmented atypical fibroxanthoma: a tumor that may be easily mistaken for malignant melanoma. Am J Dermatopathol (2003) 1.50
Merkel cell polyomavirus sequences are frequently detected in nonmelanoma skin cancer of immunosuppressed patients. Int J Cancer (2009) 1.49
Telomere length and human telomerase reverse transcriptase expression as markers for progression and prognosis of colorectal carcinoma. J Clin Oncol (2004) 1.47
STAT3 mRNA and protein expression in colorectal cancer: effects on STAT3-inducible targets linked to cell survival and proliferation. J Clin Pathol (2007) 1.46
Outback catheter for femoropopliteal occlusions: immediate and long-term results. J Endovasc Ther (2011) 1.42
Epidermotropic metastases from squamous cell carcinoma of the lower female genital tract mimicking primary Bowen's carcinoma. Am J Dermatopathol (2006) 1.42
Splicing factor Tra2-beta1 is specifically induced in breast cancer and regulates alternative splicing of the CD44 gene. Cancer Res (2006) 1.34
Expression of splicing factors in human ovarian cancer. Oncol Rep (2004) 1.31
Alpha-folate receptor expression in epithelial ovarian carcinoma and non-neoplastic ovarian tissue. Anticancer Res (2009) 1.26
Evidence of MEN-2 in the original description of classic pheochromocytoma. N Engl J Med (2007) 1.24
Predictive value of Aurora-A/STK15 expression for late stage epithelial ovarian cancer patients treated by adjuvant chemotherapy. Clin Cancer Res (2007) 1.20
Alternative splicing of Cyr61 is regulated by hypoxia and significantly changed in breast cancer. Cancer Res (2009) 1.18
Transketolase-like protein 1 (TKTL1) is required for rapid cell growth and full viability of human tumor cells. Int J Cancer (2009) 1.17
Identification of gene signatures for invasive colorectal tumor cells. Cancer Detect Prev (2007) 1.17
Prognostic significance of cytokeratin-20 reverse transcriptase polymerase chain reaction in lymph nodes of node-negative colorectal cancer patients. J Clin Oncol (2002) 1.16
T and B lymphocyte abnormalities in bone marrow biopsies of common variable immunodeficiency. Blood (2011) 1.13
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Transketolase protein TKTL1 overexpression: A potential biomarker and therapeutic target in breast cancer. Oncol Rep (2007) 1.09
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Increased expression of matrix metalloproteinase 2 in uterosacral ligaments is associated with pelvic organ prolapse. Int Urogynecol J Pelvic Floor Dysfunct (2005) 1.06
Uterosacral ligament in postmenopausal women with or without pelvic organ prolapse. Int Urogynecol J Pelvic Floor Dysfunct (2005) 1.06
Poor outcome in primary non-small cell lung cancers is predicted by transketolase TKTL1 expression. Pathology (2011) 1.05
A novel murine model of myeloproliferative disorders generated by overexpression of the transcription factor NF-E2. J Exp Med (2012) 1.05
In vivo animal trials with a scanning CO2 laser osteotome. Lasers Surg Med (2005) 1.04
EBV-infection in cardiac and non-cardiac gastric adenocarcinomas is associated with promoter methylation of p16, p14 and APC, but not hMLH1. Anal Cell Pathol (Amst) (2010) 1.04
Significance of HER2 low-level copy gain in Barrett's cancer: implications for fluorescence in situ hybridization testing in tissues. Clin Cancer Res (2007) 1.04
A novel approach for reliable microarray analysis of microdissected tumor cells from formalin-fixed and paraffin-embedded colorectal cancer resection specimens. J Mol Med (Berl) (2008) 1.04
Harmonic filters for 3D multichannel data: rotation invariant detection of mitoses in colorectal cancer. IEEE Trans Med Imaging (2010) 1.00
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Molecular modeling and description of a newly characterized activating mutation of the EGFR gene in non-small cell lung cancer. Diagn Pathol (2012) 1.00
Giant ancient schwannoma of pancreatic head treated by extended pancreatoduodenectomy. Pancreatology (2004) 1.00
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Delineation of myotoxicity induced by 3-hydroxy-3-methylglutaryl CoA reductase inhibitors in human skeletal muscle cells. J Pharmacol Exp Ther (2005) 0.99
Weak expression of focal adhesion kinase (pp125FAK) in patients with cervical cancer is associated with poor disease outcome. Clin Cancer Res (2006) 0.98
Response and prognosis after neoadjuvant chemotherapy in 1,051 patients with infiltrating lobular breast carcinoma. Breast Cancer Res Treat (2014) 0.97
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An integrated clinical-genomics approach identifies a candidate multi-analyte blood test for serous ovarian carcinoma. Clin Cancer Res (2007) 0.96
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Chromosomal imbalances are associated with metastasis-free survival in breast cancer patients. Anal Cell Pathol (2002) 0.96
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Genome-wide analysis of genetic alterations in Barrett's adenocarcinoma using single nucleotide polymorphism arrays. Lab Invest (2008) 0.88
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Quantification of CK20 gene and protein expression in colorectal cancer by RT-PCR and immunohistochemistry reveals inter- and intratumour heterogeneity. J Pathol (2002) 0.87
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