Published in Chem Res Toxicol on August 02, 2008
Redox cycling of catechol estrogens generating apurinic/apyrimidinic sites and 8-oxo-deoxyguanosine via reactive oxygen species differentiates equine and human estrogens. Chem Res Toxicol (2010) 1.07
Quantitation of DNA adducts by stable isotope dilution mass spectrometry. Chem Res Toxicol (2012) 1.00
Estrogen Receptor {alpha} Enhances the Rate of Oxidative DNA Damage by Targeting an Equine Estrogen Catechol Metabolite to the Nucleus. J Biol Chem (2009) 0.99
Mass spectrometry of structurally modified DNA. Chem Rev (2013) 0.95
Estrogen metabolism and exposure in a genotypic-phenotypic model for breast cancer risk prediction. Cancer Epidemiol Biomarkers Prev (2011) 0.90
Balance of beneficial and deleterious health effects of quinones: a case study of the chemical properties of genistein and estrone quinones. J Am Chem Soc (2009) 0.78
Human Biomonitoring of DNA Adducts by Ion Trap Multistage Mass Spectrometry. Curr Protoc Nucleic Acid Chem (2016) 0.75
Estrogen carcinogenesis in breast cancer. N Engl J Med (2006) 8.17
Estrogen and the risk of breast cancer. N Engl J Med (2001) 4.39
Molecular origin of cancer: catechol estrogen-3,4-quinones as endogenous tumor initiators. Proc Natl Acad Sci U S A (1997) 3.53
Molecular mechanisms of estrogen carcinogenesis. Annu Rev Pharmacol Toxicol (1996) 2.91
Genotoxic metabolites of estradiol in breast: potential mechanism of estradiol induced carcinogenesis. J Steroid Biochem Mol Biol (2003) 1.66
The greater reactivity of estradiol-3,4-quinone vs estradiol-2,3-quinone with DNA in the formation of depurinating adducts: implications for tumor-initiating activity. Chem Res Toxicol (2006) 1.65
Metabolism and DNA binding studies of 4-hydroxyestradiol and estradiol-3,4-quinone in vitro and in female ACI rat mammary gland in vivo. Carcinogenesis (2003) 1.65
The molecular etiology of breast cancer: evidence from biomarkers of risk. Int J Cancer (2008) 1.62
Concentrations of estrone, estradiol, and estrone sulfate and evaluation of sulfatase and aromatase activities in pre- and postmenopausal breast cancer patients. J Clin Endocrinol Metab (1996) 1.59
Relative imbalances in estrogen metabolism and conjugation in breast tissue of women with carcinoma: potential biomarkers of susceptibility to cancer. Carcinogenesis (2003) 1.39
Detection of estrogen DNA-adducts in human breast tumor tissue and healthy tissue by combined nano LC-nano ES tandem mass spectrometry. J Am Soc Mass Spectrom (2003) 1.21
Potential biomarker for early risk assessment of prostate cancer. Prostate (2006) 1.08
Cytochrome P450 1B1-mediated estrogen metabolism results in estrogen-deoxyribonucleoside adduct formation. Cancer Res (2007) 1.07
Estrogen-induced endogenous DNA adduction: possible mechanism of hormonal cancer. Proc Natl Acad Sci U S A (1986) 1.06
Spectral characterization of catechol estrogen quinone (CEQ)-derived DNA adducts and their identification in human breast tissue extract. Chem Res Toxicol (2003) 1.01
Formation of depurinating N3Adenine and N7Guanine adducts by MCF-10F cells cultured in the presence of 4-hydroxyestradiol. Int J Cancer (2007) 1.00
Bioactivation of estrone and its catechol metabolites to quinoid-glutathione conjugates in rat liver microsomes. Chem Res Toxicol (1996) 0.95
Analysis of potential biomarkers of estrogen-initiated cancer in the urine of Syrian golden hamsters treated with 4-hydroxyestradiol. Carcinogenesis (2001) 0.91
To block estrogen's synthesis or action: that is the question. J Clin Endocrinol Metab (2002) 0.90
Efficient synthesis, liquid chromatography purification, and tandem mass spectrometric characterization of estrogen-modified DNA bases. Chem Res Toxicol (2008) 0.83
Alloreactive T cells respond specifically to multiple distinct peptide-MHC complexes. Nat Immunol (2007) 2.61
Laser flash photolysis of hydrogen peroxide to oxidize protein solvent-accessible residues on the microsecond timescale. J Am Soc Mass Spectrom (2005) 2.28
US breast cancer mortality trends in young women according to race. Cancer (2014) 2.07
Comparing similar spectra: from similarity index to spectral contrast angle. J Am Soc Mass Spectrom (2002) 1.78
An endogenous peptide positively selects and augments the activation and survival of peripheral CD4+ T cells. Nat Immunol (2009) 1.78
Fast photochemical oxidation of protein footprints faster than protein unfolding. Anal Chem (2009) 1.69
Metabolism and DNA binding studies of 4-hydroxyestradiol and estradiol-3,4-quinone in vitro and in female ACI rat mammary gland in vivo. Carcinogenesis (2003) 1.65
Natural peptides selected by diabetogenic DQ8 and murine I-A(g7) molecules show common sequence specificity. J Clin Invest (2005) 1.60
Changes in sexual problems over time in women with and without early-stage breast cancer. Menopause (2010) 1.56
Positive margin rates following breast-conserving surgery for stage I-III breast cancer: palpable versus nonpalpable tumors. J Surg Res (2012) 1.53
Membrane orientation of the FMO antenna protein from Chlorobaculum tepidum as determined by mass spectrometry-based footprinting. Proc Natl Acad Sci U S A (2009) 1.53
Predictors of primary breast abscesses and recurrence. World J Surg (2009) 1.51
Top-down mass spectrometry: recent developments, applications and perspectives. Analyst (2011) 1.50
Targeting Chk1 in p53-deficient triple-negative breast cancer is therapeutically beneficial in human-in-mouse tumor models. J Clin Invest (2012) 1.49
Perioperative outcomes and complications of laparoscopic ventral hernia repair. Surgery (2005) 1.45
Isolation and molecular profiling of bone marrow micrometastases identifies TWIST1 as a marker of early tumor relapse in breast cancer patients. Clin Cancer Res (2007) 1.45
A triterpene glycoside from black cohosh that inhibits osteoclastogenesis by modulating RANKL and TNFalpha signaling pathways. Chem Biol (2007) 1.44
Temporal and spatial cooperation of Snail1 and Twist1 during epithelial-mesenchymal transition predicts for human breast cancer recurrence. Mol Cancer Res (2011) 1.42
Phycobilisomes supply excitations to both photosystems in a megacomplex in cyanobacteria. Science (2013) 1.37
IL-12p70-producing patient DC vaccine elicits Tc1-polarized immunity. J Clin Invest (2013) 1.36
2-Deoxy-D-glucose-induced cytotoxicity and radiosensitization in tumor cells is mediated via disruptions in thiol metabolism. Cancer Res (2003) 1.34
In APCs, the autologous peptides selected by the diabetogenic I-Ag7 molecule are unique and determined by the amino acid changes in the P9 pocket. J Immunol (2002) 1.32
Patient and tumor characteristics associated with increased mortality in young women (< or =40 years) with breast cancer. J Surg Oncol (2009) 1.27
Quantification of diacylglycerol molecular species in biological samples by electrospray ionization mass spectrometry after one-step derivatization. Anal Chem (2007) 1.26
Native electrospray and electron-capture dissociation FTICR mass spectrometry for top-down studies of protein assemblies. Anal Chem (2011) 1.25
Disparities related to socioeconomic status and access to medical care remain in the United States among women who never had a mammogram. Cancer Causes Control (2003) 1.24
Quantification of protein-ligand interactions by mass spectrometry, titration, and H/D exchange: PLIMSTEX. J Am Chem Soc (2003) 1.23
Catechol ortho-quinones: the electrophilic compounds that form depurinating DNA adducts and could initiate cancer and other diseases. Carcinogenesis (2002) 1.19
An electrically compensated trap designed to eighth order for FT-ICR mass spectrometry. J Am Soc Mass Spectrom (2008) 1.19
A mass spectrometric approach to the study of DNA-binding proteins: interaction of human TRF2 with telomeric DNA. Biochemistry (2008) 1.17
Predictors of complete pathological response after neoadjuvant systemic therapy for breast cancer. Am J Surg (2009) 1.16
Evaluation of different combinations of gated trapping, RF-only mode and trap compensation for in-field MALDI Fourier transform mass spectrometry. J Am Soc Mass Spectrom (2004) 1.14
Molecular mechanism of photoactivation and structural location of the cyanobacterial orange carotenoid protein. Biochemistry (2013) 1.13
Temperature jump and fast photochemical oxidation probe submillisecond protein folding. J Am Chem Soc (2010) 1.12
Interactions of apurinic/apyrimidinic endonuclease with a redox inhibitor: evidence for an alternate conformation of the enzyme. Biochemistry (2010) 1.10
Hydrogen/deuterium exchange and electron-transfer dissociation mass spectrometry determine the interface and dynamics of apolipoprotein E oligomerization. Biochemistry (2011) 1.09
Treatment and outcomes of patients with primary breast sarcoma. Am J Surg (2008) 1.07
G-quadruplex formation of thrombin-binding aptamer detected by electrospray ionization mass spectrometry. J Am Chem Soc (2003) 1.06
Native mass spectrometry characterization of intact nanodisc lipoprotein complexes. Anal Chem (2012) 1.06
Native electrospray and electron-capture dissociation in FTICR mass spectrometry provide top-down sequencing of a protein component in an intact protein assembly. J Am Soc Mass Spectrom (2010) 1.06
Fast photochemical oxidation of proteins for epitope mapping. Anal Chem (2011) 1.04
Fast photochemical oxidation of proteins and mass spectrometry follow submillisecond protein folding at the amino-acid level. J Am Chem Soc (2012) 1.04
Functional analysis of novel analogues of E3330 that block the redox signaling activity of the multifunctional AP endonuclease/redox signaling enzyme APE1/Ref-1. Antioxid Redox Signal (2011) 1.03
Mass spectrometry-based protein footprinting characterizes the structures of oligomeric apolipoprotein E2, E3, and E4. Biochemistry (2011) 1.02
Correlates of fear of cancer recurrence in women with ductal carcinoma in situ and early invasive breast cancer. Breast Cancer Res Treat (2011) 1.02
Fast photochemical oxidation of proteins for comparing structures of protein-ligand complexes: the calmodulin-peptide model system. Anal Chem (2010) 1.01
Sulfate radical anion as a new reagent for fast photochemical oxidation of proteins. Anal Chem (2010) 1.00
Psb27, a transiently associated protein, binds to the chlorophyll binding protein CP43 in photosystem II assembly intermediates. Proc Natl Acad Sci U S A (2011) 1.00
Probing Ca2+-induced conformational changes in porcine calmodulin by H/D exchange and ESI-MS: effect of cations and ionic strength. Biochemistry (2003) 1.00
A longitudinal study of factors associated with perceived risk of recurrence in women with ductal carcinoma in situ and early-stage invasive breast cancer. Breast Cancer Res Treat (2010) 1.00
Combined charged residue-field emission model of macromolecular electrospray ionization. Anal Chem (2009) 0.99
Scientific Presentation Award: The combination of axillary ultrasound and ultrasound-guided biopsy is an accurate predictor of axillary stage in clinically node-negative breast cancer patients. Am J Surg (2008) 0.99
Charge carrier field emission determines the number of charges on native state proteins in electrospray ionization. J Am Chem Soc (2008) 0.99
Fast photochemical oxidation of proteins (FPOP) maps the epitope of EGFR binding to adnectin. J Am Soc Mass Spectrom (2014) 0.98
Characterization of structural variations in the peptidoglycan of vancomycin-susceptible Enterococcus faecium: understanding glycopeptide-antibiotic binding sites using mass spectrometry. J Am Soc Mass Spectrom (2008) 0.98
MS-based cross-linking analysis reveals the location of the PsbQ protein in cyanobacterial photosystem II. Proc Natl Acad Sci U S A (2014) 0.98
Ionic-liquid matrices for improved analysis of phospholipids by MALDI-TOF mass spectrometry. J Am Soc Mass Spectrom (2005) 0.98
Ankle syndesmosis injuries: anatomy, biomechanics, mechanism of injury, and clinical guidelines for diagnosis and intervention. J Orthop Sports Phys Ther (2006) 0.98
Native electrospray mass spectrometry reveals the nature and stoichiometry of pigments in the FMO photosynthetic antenna protein. Biochemistry (2011) 0.98
Accuracy of ultrasonography and mammography in predicting pathologic response after neoadjuvant chemotherapy for breast cancer. Am J Surg (2010) 0.98
A single peptide-MHC complex positively selects a diverse and specific CD8 T cell repertoire. Science (2009) 0.97
Neoadjuvant chemotherapy is associated with improved survival compared with adjuvant chemotherapy in patients with triple-negative breast cancer only after complete pathologic response. Ann Surg Oncol (2011) 0.97
Accuracy of perceived risk of recurrence among patients with early-stage breast cancer. Cancer Epidemiol Biomarkers Prev (2010) 0.97
Metastatic disease to the breast: the Washington University experience. World J Surg Oncol (2007) 0.95
Ionic-liquid matrices for quantitative analysis by MALDI-TOF mass spectrometry. J Am Soc Mass Spectrom (2004) 0.94
Specificity of peptide selection by antigen-presenting cells homozygous or heterozygous for expression of class II MHC molecules: The lack of competition. Proc Natl Acad Sci U S A (2003) 0.94
First signature of islet beta-cell-derived naturally processed peptides selected by diabetogenic class II MHC molecules. J Immunol (2008) 0.94
A gene expression signature that predicts the therapeutic response of the basal-like breast cancer to neoadjuvant chemotherapy. Breast Cancer Res Treat (2009) 0.93
Mass spectrometry footprinting reveals the structural rearrangements of cyanobacterial orange carotenoid protein upon light activation. Biochim Biophys Acta (2014) 0.92
Characterization of the redox activity and disulfide bond formation in apurinic/apyrimidinic endonuclease. Biochemistry (2012) 0.92
Assessment of progesterone receptors in breast carcinoma by PET with 21-18F-fluoro-16α,17α-[(R)-(1'-α-furylmethylidene)dioxy]-19-norpregn-4-ene-3,20-dione. J Nucl Med (2012) 0.92
Mass spectrometry-based carboxyl footprinting of proteins: method evaluation. Int J Mass Spectrom (2012) 0.91
Structural model and spectroscopic characteristics of the FMO antenna protein from the aerobic chlorophototroph, Candidatus Chloracidobacterium thermophilum. Biochim Biophys Acta (2010) 0.91
Pulsed hydrogen-deuterium exchange mass spectrometry probes conformational changes in amyloid beta (Aβ) peptide aggregation. Proc Natl Acad Sci U S A (2013) 0.91
Carboxyl-group footprinting maps the dimerization interface and phosphorylation-induced conformational changes of a membrane-associated tyrosine kinase. Mol Cell Proteomics (2011) 0.91
Chemosensitizing and cytotoxic effects of 2-deoxy-D-glucose on breast cancer cells. J Cancer Res Ther (2009) 0.90
Assessment of cellular proliferation in tumors by PET using 18F-ISO-1. J Nucl Med (2013) 0.90
Fast photochemical oxidation of proteins for comparing solvent-accessibility changes accompanying protein folding: data processing and application to barstar. Biochim Biophys Acta (2013) 0.90
Online, high-pressure digestion system for protein characterization by hydrogen/deuterium exchange and mass spectrometry. Anal Chem (2010) 0.90
Improved mass spectrometric characterization of protein glycosylation reveals unusual glycosylation of maize-derived bovine trypsin. Anal Chem (2010) 0.90
Identification of naturally processed peptides bound to the class I MHC molecule H-2Kd of normal and TAP-deficient cells. Eur J Immunol (2006) 0.90
Miniaturizing sample spots for matrix-assisted laser desorption/ionization mass spectrometry. Trends Analyt Chem (2009) 0.90
Breast cancer in elderly women (≥ 80 years): variation in standard of care? J Surg Oncol (2010) 0.89
Inhibition of apurinic/apyrimidinic endonuclease I's redox activity revisited. Biochemistry (2013) 0.89
APCs present A beta(k)-derived peptides that are autoantigenic to type B T cells. J Immunol (2003) 0.89
Interpretation and deconvolution of nanodisc native mass spectra. J Am Soc Mass Spectrom (2013) 0.89
H/D exchange centroid monitoring is insufficient to show differences in the behavior of protein states. J Am Soc Mass Spectrom (2013) 0.89
An improved fast photochemical oxidation of proteins (FPOP) platform for protein therapeutics. J Am Soc Mass Spectrom (2014) 0.89
Modeling data from titration, amide H/D exchange, and mass spectrometry to obtain protein-ligand binding constants. J Am Soc Mass Spectrom (2004) 0.88
Method revealing bacterial cell-wall architecture by time-dependent isotope labeling and quantitative liquid chromatography/mass spectrometry. Anal Chem (2009) 0.88
Gas-phase nazarov cyclization of protonated 2-methoxy and 2-hydroxychalcone: an example of intramolecular proton-transport catalysis. J Am Soc Mass Spectrom (2008) 0.88
The impact of breast MRI on surgical decision-making: are patients at risk for mastectomy? J Surg Oncol (2009) 0.88
Metal-binding properties of human centrin-2 determined by micro-electrospray ionization mass spectrometry and UV spectroscopy. J Am Soc Mass Spectrom (2006) 0.88
Hydrogen-deuterium exchange mass spectrometry reveals the interaction of Fenna-Matthews-Olson protein and chlorosome CsmA protein. Biochemistry (2011) 0.87
Protonated nitro group as a gas-phase electrophile: experimental and theoretical study of the cyclization of o-nitrodiphenyl ethers, amines, and sulfides. J Am Soc Mass Spectrom (2007) 0.87
Shared management of a rare necrotizing soft tissue infection of the breast. Breast J (2009) 0.87
Improving the signal intensity and sensitivity of MALDI mass spectrometry by using nanoliter spots deposited by induction-based fluidics. J Am Soc Mass Spectrom (2008) 0.87
S-glutathionylation of cysteine 99 in the APE1 protein impairs abasic endonuclease activity. J Mol Biol (2011) 0.86
New protein footprinting: fast photochemical iodination combined with top-down and bottom-up mass spectrometry. J Am Soc Mass Spectrom (2012) 0.86
Photocrosslinking of human telomeric G-quadruplex loops by anti cyclobutane thymine dimer formation. Proc Natl Acad Sci U S A (2009) 0.86