Published in Chest on August 08, 2008
Age-, sex-, and race-based differences among patients enrolled versus not enrolled in acute lung injury clinical trials. Crit Care Med (2010) 1.71
Strategies to Maximize Enrollment in a Prospective Study of Comatose Children in the PICU. Pediatr Crit Care Med (2016) 1.40
Prevalence and impact of active and passive cigarette smoking in acute respiratory distress syndrome. Crit Care Med (2014) 1.01
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Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med (2000) 48.03
Higher versus lower positive end-expiratory pressures in patients with the acute respiratory distress syndrome. N Engl J Med (2004) 11.78
Pulmonary dead-space fraction as a risk factor for death in the acute respiratory distress syndrome. N Engl J Med (2002) 6.17
Lower tidal volume ventilation and plasma cytokine markers of inflammation in patients with acute lung injury. Crit Care Med (2005) 5.76
Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice. J Immunol (2007) 5.66
Who should receive life support during a public health emergency? Using ethical principles to improve allocation decisions. Ann Intern Med (2009) 5.35
Randomized, placebo-controlled clinical trial of an aerosolized β₂-agonist for treatment of acute lung injury. Am J Respir Crit Care Med (2011) 5.24
An official American Thoracic Society workshop report: features and measurements of experimental acute lung injury in animals. Am J Respir Cell Mol Biol (2011) 4.65
Clinical implementation of the ARDS network protocol is associated with reduced hospital mortality compared with historical controls. Crit Care Med (2005) 3.86
Recent trends in acute lung injury mortality: 1996-2005. Crit Care Med (2009) 3.86
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Allogeneic human mesenchymal stem cells for treatment of E. coli endotoxin-induced acute lung injury in the ex vivo perfused human lung. Proc Natl Acad Sci U S A (2009) 3.84
Prevention of ventilator-associated pneumonia: an evidence-based systematic review. Ann Intern Med (2003) 3.74
Acute traumatic coagulopathy: initiated by hypoperfusion: modulated through the protein C pathway? Ann Surg (2007) 3.49
Rosuvastatin for sepsis-associated acute respiratory distress syndrome. N Engl J Med (2014) 3.39
Receptor for advanced glycation end-products is a marker of type I cell injury in acute lung injury. Am J Respir Crit Care Med (2006) 3.38
Pathogenetic and prognostic significance of altered coagulation and fibrinolysis in acute lung injury/acute respiratory distress syndrome. Crit Care Med (2007) 3.31
Randomized clinical trial of activated protein C for the treatment of acute lung injury. Am J Respir Crit Care Med (2008) 3.28
Effect of prone positioning on clinical outcomes in children with acute lung injury: a randomized controlled trial. JAMA (2005) 3.21
Transfusion-related acute lung injury: incidence and risk factors. Blood (2011) 3.12
Platelet depletion and aspirin treatment protect mice in a two-event model of transfusion-related acute lung injury. J Clin Invest (2009) 3.08
Polymorphonuclear leukocytes mediate Staphylococcus aureus Panton-Valentine leukocidin-induced lung inflammation and injury. Proc Natl Acad Sci U S A (2010) 3.05
Nonventilatory treatments for acute lung injury and ARDS. Chest (2007) 3.02
Elevated levels of plasminogen activator inhibitor-1 in pulmonary edema fluid are associated with mortality in acute lung injury. Am J Physiol Lung Cell Mol Physiol (2003) 3.02
Postobstructive pulmonary edema: a case for hydrostatic mechanisms. Chest (2007) 2.97
Cytokine-mediated inflammation in acute lung injury. Cytokine Growth Factor Rev (2003) 2.95
Rationing critical care beds: a systematic review. Crit Care Med (2004) 2.86
Trauma-associated lung injury differs clinically and biologically from acute lung injury due to other clinical disorders. Crit Care Med (2007) 2.79
Antibacterial effect of human mesenchymal stem cells is mediated in part from secretion of the antimicrobial peptide LL-37. Stem Cells (2010) 2.72
Subglottic secretion drainage for preventing ventilator-associated pneumonia: a meta-analysis. Am J Med (2005) 2.67
Clinically relevant concentrations of beta2-adrenergic agonists stimulate maximal cyclic adenosine monophosphate-dependent airspace fluid clearance and decrease pulmonary edema in experimental acid-induced lung injury. Crit Care Med (2004) 2.66
Mesenchymal stem cells and idiopathic pulmonary fibrosis. Potential for clinical testing. Am J Respir Crit Care Med (2013) 2.66
The uncommon case of Jahi McMath. Chest (2015) 2.65
Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death. Nat Med (2006) 2.63
Effects of recruitment maneuvers in patients with acute lung injury and acute respiratory distress syndrome ventilated with high positive end-expiratory pressure. Crit Care Med (2003) 2.63
Clinical practice. Acute pulmonary edema. N Engl J Med (2005) 2.62
Higher urine nitric oxide is associated with improved outcomes in patients with acute lung injury. Am J Respir Crit Care Med (2006) 2.61
Decisions to limit life-sustaining treatment for critically ill patients who lack both decision-making capacity and surrogate decision-makers. Crit Care Med (2006) 2.61
Transfusion-related acute lung injury: a review. Chest (2004) 2.56
Acute kidney injury in patients with acute lung injury: impact of fluid accumulation on classification of acute kidney injury and associated outcomes. Crit Care Med (2011) 2.55
Simvastatin decreases lipopolysaccharide-induced pulmonary inflammation in healthy volunteers. Am J Respir Crit Care Med (2009) 2.52
Pediatric acute lung injury: prospective evaluation of risk factors associated with mortality. Am J Respir Crit Care Med (2004) 2.51
Neutrophils and their Fc gamma receptors are essential in a mouse model of transfusion-related acute lung injury. J Clin Invest (2006) 2.50
Significance of von Willebrand factor in septic and nonseptic patients with acute lung injury. Am J Respir Crit Care Med (2004) 2.49
Pharmacotherapy of acute lung injury and the acute respiratory distress syndrome. J Intensive Care Med (2006) 2.47
Are physicians' recommendations to limit life support beneficial or burdensome? Bringing empirical data to the debate. Am J Respir Crit Care Med (2009) 2.46
Prolonged hypoxia differentially regulates hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression in lung epithelial cells: implication of natural antisense HIF-1alpha. J Biol Chem (2004) 2.42
Quality indicators for end-of-life care in the intensive care unit. Crit Care Med (2003) 2.42
Concise review: Mesenchymal stem cells for acute lung injury: role of paracrine soluble factors. Stem Cells (2011) 2.41
Low tidal volume reduces epithelial and endothelial injury in acid-injured rat lungs. Am J Respir Crit Care Med (2002) 2.40
Ligation of protease-activated receptor 1 enhances alpha(v)beta6 integrin-dependent TGF-beta activation and promotes acute lung injury. J Clin Invest (2006) 2.40
Surrogate decision-makers' perspectives on discussing prognosis in the face of uncertainty. Am J Respir Crit Care Med (2008) 2.40
Active and passive cigarette smoking and acute lung injury after severe blunt trauma. Am J Respir Crit Care Med (2011) 2.39
Protein C and thrombomodulin in human acute lung injury. Am J Physiol Lung Cell Mol Physiol (2003) 2.37
Therapeutic effects of human mesenchymal stem cells in ex vivo human lungs injured with live bacteria. Am J Respir Crit Care Med (2013) 2.34
Fas and fas ligand are up-regulated in pulmonary edema fluid and lung tissue of patients with acute lung injury and the acute respiratory distress syndrome. Am J Pathol (2002) 2.30
"It's not just what the doctor tells me:" factors that influence surrogate decision-makers' perceptions of prognosis. Crit Care Med (2010) 2.25
Alveolar epithelial ion and fluid transport: recent progress. Am J Respir Cell Mol Biol (2006) 2.20
Informed consent in research to improve the number and quality of deceased donor organs. Crit Care Med (2011) 2.18
Plasma angiopoietin-2 predicts the onset of acute lung injury in critically ill patients. Am J Respir Crit Care Med (2013) 2.17
Prognostic and pathogenetic value of combining clinical and biochemical indices in patients with acute lung injury. Chest (2009) 2.17
Elevated plasma levels of soluble TNF receptors are associated with morbidity and mortality in patients with acute lung injury. Am J Physiol Lung Cell Mol Physiol (2004) 2.15
Racial and ethnic disparities in mortality from acute lung injury. Crit Care Med (2009) 2.14
Intensive care of human immunodeficiency virus-infected patients during the era of highly active antiretroviral therapy. Am J Respir Crit Care Med (2002) 2.12
Therapeutic strategies for severe acute lung injury. Crit Care Med (2010) 2.12
Direct visual instillation as a method for efficient delivery of fluid into the distal airspaces of anesthetized mice. Exp Lung Res (2004) 2.12
Keratinocyte and hepatocyte growth factors in the lung: roles in lung development, inflammation, and repair. Am J Physiol Lung Cell Mol Physiol (2002) 2.10
Timing of Intubation and Clinical Outcomes in Adults With Acute Respiratory Distress Syndrome. Crit Care Med (2016) 2.08
Sugar administration is an effective adjunctive therapy in the treatment of Pseudomonas aeruginosa pneumonia. Am J Physiol Lung Cell Mol Physiol (2013) 2.04
Plasma biomarker profiles in acute exacerbation of idiopathic pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol (2010) 2.03
Mesenchymal stem cells enhance survival and bacterial clearance in murine Escherichia coli pneumonia. Thorax (2012) 2.02
Chronic disorders of consciousness following coma: Part one: medical issues. Chest (2013) 1.98
Functional identification of the alveolar edema reabsorption activity of murine tumor necrosis factor-alpha. Am J Respir Crit Care Med (2003) 1.98
Early elevation of plasma soluble intercellular adhesion molecule-1 in pediatric acute lung injury identifies patients at increased risk of death and prolonged mechanical ventilation. Pediatr Crit Care Med (2003) 1.98
Prognostic value of surfactant proteins A and D in patients with acute lung injury. Crit Care Med (2003) 1.96
Early elevation of plasma von Willebrand factor antigen in pediatric acute lung injury is associated with an increased risk of death and prolonged mechanical ventilation. Pediatr Crit Care Med (2007) 1.92
Prognostic value of the pulmonary dead-space fraction during the first 6 days of acute respiratory distress syndrome. Respir Care (2004) 1.92
Transforming growth factor-beta1 decreases expression of the epithelial sodium channel alphaENaC and alveolar epithelial vectorial sodium and fluid transport via an ERK1/2-dependent mechanism. J Biol Chem (2003) 1.90
Contribution of CFTR to apical-basolateral fluid transport in cultured human alveolar epithelial type II cells. Am J Physiol Lung Cell Mol Physiol (2005) 1.87
Allogeneic human mesenchymal stem cells restore epithelial protein permeability in cultured human alveolar type II cells by secretion of angiopoietin-1. J Biol Chem (2010) 1.86
Interleukin-1beta decreases expression of the epithelial sodium channel alpha-subunit in alveolar epithelial cells via a p38 MAPK-dependent signaling pathway. J Biol Chem (2005) 1.86
Biomarkers increase detection of active smoking and secondhand smoke exposure in critically ill patients. Crit Care Med (2011) 1.86
Proteinase-activated receptor-1 mediates elastase-induced apoptosis of human lung epithelial cells. Am J Respir Cell Mol Biol (2005) 1.83
Elevation of KL-6, a lung epithelial cell marker, in plasma and epithelial lining fluid in acute respiratory distress syndrome. Am J Physiol Lung Cell Mol Physiol (2003) 1.82
Stimulation of alveolar epithelial fluid clearance in human lungs by exogenous epinephrine. Crit Care Med (2006) 1.81
Plasma angiopoietin-2 in clinical acute lung injury: prognostic and pathogenetic significance. Crit Care Med (2012) 1.81
Acute lung injury: epidemiology, pathogenesis, and treatment. J Aerosol Med Pulm Drug Deliv (2010) 1.78
Physicians should administer low-dose corticosteroids selectively to septic patients until an ongoing trial is completed. Ann Intern Med (2004) 1.76
Accuracy of physiologic dead space measurements in patients with acute respiratory distress syndrome using volumetric capnography: comparison with the metabolic monitor method. Respir Care (2005) 1.75
Human mesenchymal stem cells reduce mortality and bacteremia in gram-negative sepsis in mice in part by enhancing the phagocytic activity of blood monocytes. Am J Physiol Lung Cell Mol Physiol (2012) 1.74
Interleukin-1beta causes acute lung injury via alphavbeta5 and alphavbeta6 integrin-dependent mechanisms. Circ Res (2008) 1.73
Predictive and pathogenetic value of plasma biomarkers for acute kidney injury in patients with acute lung injury. Crit Care Med (2007) 1.73
Science review: mechanisms of ventilator-induced injury. Crit Care (2002) 1.71
Age-, sex-, and race-based differences among patients enrolled versus not enrolled in acute lung injury clinical trials. Crit Care Med (2010) 1.71
One-year mortality and predictors of death among hospital survivors of acute respiratory distress syndrome. Intensive Care Med (2014) 1.70
Acute effects of tidal volume strategy on hemodynamics, fluid balance, and sedation in acute lung injury. Crit Care Med (2005) 1.70
Biomarkers of inflammation, coagulation and fibrinolysis predict mortality in acute lung injury. Crit Care (2008) 1.69
Human mesenchymal stem cell microvesicles for treatment of Escherichia coli endotoxin-induced acute lung injury in mice. Stem Cells (2014) 1.63
Beta-adrenergic agonist therapy as a potential treatment for acute lung injury. Am J Respir Crit Care Med (2006) 1.63
Physiological and biochemical markers of alveolar epithelial barrier dysfunction in perfused human lungs. Am J Physiol Lung Cell Mol Physiol (2007) 1.63