PubRank

Stefan M V Freund

Author PubWeight™ 55.08‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The complete folding pathway of a protein from nanoseconds to microseconds. Nature 2003 3.61
2 LC3C, bound selectively by a noncanonical LIR motif in NDP52, is required for antibacterial autophagy. Mol Cell 2012 2.41
3 Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase Cezanne. Nat Struct Mol Biol 2010 2.31
4 Molecular basis of histone H3K36me3 recognition by the PWWP domain of Brpf1. Nat Struct Mol Biol 2010 2.15
5 Quaternary structures of tumor suppressor p53 and a specific p53 DNA complex. Proc Natl Acad Sci U S A 2007 2.09
6 OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis. Cell 2013 2.05
7 Molecular mechanism of the interaction between MDM2 and p53. J Mol Biol 2002 2.03
8 FtsA forms actin-like protofilaments. EMBO J 2012 2.00
9 Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome. Genes Dev 2011 1.89
10 Core domain interactions in full-length p53 in solution. Proc Natl Acad Sci U S A 2006 1.59
11 A peptide that binds and stabilizes p53 core domain: chaperone strategy for rescue of oncogenic mutants. Proc Natl Acad Sci U S A 2002 1.58
12 Solution structure of p53 core domain: structural basis for its instability. Proc Natl Acad Sci U S A 2006 1.53
13 The denatured state of Engrailed Homeodomain under denaturing and native conditions. J Mol Biol 2003 1.51
14 Characterization of the p53-rescue drug CP-31398 in vitro and in living cells. Oncogene 2002 1.51
15 NMR resonance assignments of thrombin reveal the conformational and dynamic effects of ligation. Proc Natl Acad Sci U S A 2010 1.38
16 Assembly, analysis and architecture of atypical ubiquitin chains. Nat Struct Mol Biol 2013 1.27
17 Comparative biophysical characterization of p53 with the pro-apoptotic BAK and the anti-apoptotic BCL-xL. J Biol Chem 2007 1.23
18 Recognition of DNA by p53 core domain and location of intermolecular contacts of cooperative binding. J Mol Biol 2002 1.22
19 Regulation of DNA binding of p53 by its C-terminal domain. J Mol Biol 2004 1.22
20 CRINEPT-TROSY NMR reveals p53 core domain bound in an unfolded form to the chaperone Hsp90. Proc Natl Acad Sci U S A 2002 1.17
21 Hydrophobic core fluidity of homologous protein domains: relation of side-chain dynamics to core composition and packing. Biochemistry 2004 1.08
22 The malignant brain tumor repeats of human SCML2 bind to peptides containing monomethylated lysine. J Mol Biol 2008 1.07
23 Modulation of binding of DNA to the C-terminal domain of p53 by acetylation. Structure 2005 1.06
24 Interaction of the p53 DNA-binding domain with its n-terminal extension modulates the stability of the p53 tetramer. J Mol Biol 2011 1.04
25 Effects of oncogenic mutations and DNA response elements on the binding of p53 to p53-binding protein 2 (53BP2). J Biol Chem 2006 1.04
26 HIV-1 capsid undergoes coupled binding and isomerization by the nuclear pore protein NUP358. Retrovirology 2013 1.01
27 An ensemble view of thrombin allostery. Biol Chem 2012 0.94
28 Crystal structures of engrailed homeodomain mutants: implications for stability and dynamics. J Biol Chem 2003 0.94
29 Binding of EMSY to HP1beta: implications for recruitment of HP1beta and BS69. EMBO Rep 2005 0.90
30 Molecular basis of the interactions between the p73 N terminus and p300: effects on transactivation and modulation by phosphorylation. Proc Natl Acad Sci U S A 2009 0.89
31 Thermodynamic origins of protein folding, allostery, and capsid formation in the human hepatitis B virus core protein. Proc Natl Acad Sci U S A 2013 0.89
32 Structural distortion of p53 by the mutation R249S and its rescue by a designed peptide: implications for "mutant conformation". J Mol Biol 2004 0.89
33 The V86M mutation in HIV-1 capsid confers resistance to TRIM5α by abrogation of cyclophilin A-dependent restriction and enhancement of viral nuclear import. Retrovirology 2013 0.87
34 Structural basis of p63α SAM domain mutants involved in AEC syndrome. FEBS J 2011 0.84
35 Stabilising the DNA-binding domain of p53 by rational design of its hydrophobic core. Protein Eng Des Sel 2009 0.84
36 An essential role for the ATG8 ortholog LC3C in antibacterial autophagy. Autophagy 2013 0.82
37 Role of conformational heterogeneity in domain swapping and adapter function of the Cks proteins. J Biol Chem 2005 0.82
38 Diverse HIV viruses are targeted by a conformationally dynamic antiviral. Nat Struct Mol Biol 2012 0.81
39 Solution structure of the FCS zinc finger domain of the human polycomb group protein L(3)mbt-like 2. Protein Sci 2009 0.81
40 Solution structure of the BRK domains from CHD7. J Mol Biol 2007 0.81
41 The hepatitis B virus preS1 domain hijacks host trafficking proteins by motif mimicry. Nat Chem Biol 2013 0.79
42 Molecular basis for modulation of the p53 target selectivity by KLF4. PLoS One 2012 0.78