Published in J Mol Biol on August 03, 2008
Recognition of multivalent histone states associated with heterochromatin by UHRF1 protein. J Biol Chem (2011) 1.79
MBT domain proteins in development and disease. Semin Cell Dev Biol (2009) 1.49
Molecular recognition of histone lysine methylation by the Polycomb group repressor dSfmbt. EMBO J (2009) 1.42
Methylation-state-specific recognition of histones by the MBT repeat protein L3MBTL2. Nucleic Acids Res (2009) 1.32
L3MBTL2 protein acts in concert with PcG protein-mediated monoubiquitination of H2A to establish a repressive chromatin structure. Mol Cell (2011) 1.32
Keeping it in the family: diverse histone recognition by conserved structural folds. Crit Rev Biochem Mol Biol (2010) 1.29
Comparative analysis of chromatin binding by Sex Comb on Midleg (SCM) and other polycomb group repressors at a Drosophila Hox gene. Mol Cell Biol (2010) 1.05
Combinatorial readout of dual histone modifications by paired chromatin-associated modules. J Biol Chem (2011) 1.04
Structural studies of a four-MBT repeat protein MBTD1. PLoS One (2009) 1.03
Chromatin regulation: how complex does it get? Epigenetics (2014) 0.96
Interactions with RNA direct the Polycomb group protein SCML2 to chromatin where it represses target genes. Elife (2014) 0.93
Identification of non-peptide malignant brain tumor (MBT) repeat antagonists by virtual screening of commercially available compounds. J Med Chem (2010) 0.92
H3K9me2/3 binding of the MBT domain protein LIN-61 is essential for Caenorhabditis elegans vulva development. PLoS Genet (2011) 0.88
Drug discovery toward antagonists of methyl-lysine binding proteins. Curr Chem Genomics (2011) 0.84
Epigenetics: Tools and Technologies. Drug Discov Today Technol (2010) 0.83
SUMOylation of the polycomb group protein L3MBTL2 facilitates repression of its target genes. Nucleic Acids Res (2013) 0.81
Polycomb protein SCML2 associates with USP7 and counteracts histone H2A ubiquitination in the XY chromatin during male meiosis. PLoS Genet (2015) 0.79
Molecular basis of PRC1 targeting to Polycomb response elements by PhoRC. Genes Dev (2016) 0.79
Cation-π interactions of methylated ammonium ions: a quantum mechanical study. Proteins (2014) 0.77
Solution NMR structure of the DNA-binding domain from Scml2 (sex comb on midleg-like 2). J Biol Chem (2014) 0.77
The macro domain is an ADP-ribose binding module. EMBO J (2005) 4.07
The complete folding pathway of a protein from nanoseconds to microseconds. Nature (2003) 3.61
Solution structure of the nonmethyl-CpG-binding CXXC domain of the leukaemia-associated MLL histone methyltransferase. EMBO J (2006) 2.89
Mechanism of activation and inhibition of the HER4/ErbB4 kinase. Structure (2008) 2.79
LC3C, bound selectively by a noncanonical LIR motif in NDP52, is required for antibacterial autophagy. Mol Cell (2012) 2.41
Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase Cezanne. Nat Struct Mol Biol (2010) 2.31
Molecular basis of histone H3K36me3 recognition by the PWWP domain of Brpf1. Nat Struct Mol Biol (2010) 2.15
Quaternary structures of tumor suppressor p53 and a specific p53 DNA complex. Proc Natl Acad Sci U S A (2007) 2.09
OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis. Cell (2013) 2.05
Molecular mechanism of the interaction between MDM2 and p53. J Mol Biol (2002) 2.03
FtsA forms actin-like protofilaments. EMBO J (2012) 2.00
Comparative binding of p53 to its promoter and DNA recognition elements. J Mol Biol (2005) 1.96
Crystal structure of a superstable mutant of human p53 core domain. Insights into the mechanism of rescuing oncogenic mutations. J Biol Chem (2003) 1.94
Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome. Genes Dev (2011) 1.89
Four domains of p300 each bind tightly to a sequence spanning both transactivation subdomains of p53. Proc Natl Acad Sci U S A (2007) 1.86
The FtsK gamma domain directs oriented DNA translocation by interacting with KOPS. Nat Struct Mol Biol (2006) 1.76
Structure of the Jab1/MPN domain and its implications for proteasome function. Biochemistry (2003) 1.64
Core domain interactions in full-length p53 in solution. Proc Natl Acad Sci U S A (2006) 1.59
A peptide that binds and stabilizes p53 core domain: chaperone strategy for rescue of oncogenic mutants. Proc Natl Acad Sci U S A (2002) 1.58
Molecular mechanism of sequence-directed DNA loading and translocation by FtsK. Mol Cell (2008) 1.54
Solution structure of p53 core domain: structural basis for its instability. Proc Natl Acad Sci U S A (2006) 1.53
Ultra-fast barrier-limited folding in the peripheral subunit-binding domain family. J Mol Biol (2005) 1.52
The denatured state of Engrailed Homeodomain under denaturing and native conditions. J Mol Biol (2003) 1.51
Characterization of the p53-rescue drug CP-31398 in vitro and in living cells. Oncogene (2002) 1.51
Solution structure of the Kaposi's sarcoma-associated herpesvirus K3 N-terminal domain reveals a Novel E2-binding C4HC3-type RING domain. J Biol Chem (2004) 1.50
The crystal structure of AF1521 a protein from Archaeoglobus fulgidus with homology to the non-histone domain of macroH2A. J Mol Biol (2003) 1.44
Crystal structure of foot-and-mouth disease virus 3C protease. New insights into catalytic mechanism and cleavage specificity. J Biol Chem (2005) 1.38
NMR resonance assignments of thrombin reveal the conformational and dynamic effects of ligation. Proc Natl Acad Sci U S A (2010) 1.38
Crystal structure of the malignant brain tumor (MBT) repeats in Sex Comb on Midleg-like 2 (SCML2). J Biol Chem (2003) 1.37
Assembly, analysis and architecture of atypical ubiquitin chains. Nat Struct Mol Biol (2013) 1.27
The structure of an FF domain from human HYPA/FBP11. J Mol Biol (2002) 1.27
Structural variation in PWWP domains. J Mol Biol (2003) 1.24
mTORC1 activation regulates beta-cell mass and proliferation by modulation of cyclin D2 synthesis and stability. J Biol Chem (2009) 1.24
Comparative biophysical characterization of p53 with the pro-apoptotic BAK and the anti-apoptotic BCL-xL. J Biol Chem (2007) 1.23
Recognition of DNA by p53 core domain and location of intermolecular contacts of cooperative binding. J Mol Biol (2002) 1.22
Regulation of DNA binding of p53 by its C-terminal domain. J Mol Biol (2004) 1.22
Designing an extracellular matrix protein with enhanced mechanical stability. Proc Natl Acad Sci U S A (2007) 1.19
Structural consequences of nucleophosmin mutations in acute myeloid leukemia. J Biol Chem (2008) 1.18
CRINEPT-TROSY NMR reveals p53 core domain bound in an unfolded form to the chaperone Hsp90. Proc Natl Acad Sci U S A (2002) 1.17
Acetylation of lysine 120 of p53 endows DNA-binding specificity at effective physiological salt concentration. Proc Natl Acad Sci U S A (2011) 1.16
The structure of the AXH domain of spinocerebellar ataxin-1. J Biol Chem (2003) 1.13
The UBAP1 subunit of ESCRT-I interacts with ubiquitin via a SOUBA domain. Structure (2012) 1.09
Hydrophobic core fluidity of homologous protein domains: relation of side-chain dynamics to core composition and packing. Biochemistry (2004) 1.08
The PUB domain functions as a p97 binding module in human peptide N-glycanase. J Biol Chem (2006) 1.08
Modulation of binding of DNA to the C-terminal domain of p53 by acetylation. Structure (2005) 1.06
Solution structure of the C4 zinc finger domain of HDM2. Protein Sci (2005) 1.06
Simulation and experiment at high temperatures: ultrafast folding of a thermophilic protein by nucleation-condensation. J Mol Biol (2005) 1.06
Interaction of the p53 DNA-binding domain with its n-terminal extension modulates the stability of the p53 tetramer. J Mol Biol (2011) 1.04
Effects of oncogenic mutations and DNA response elements on the binding of p53 to p53-binding protein 2 (53BP2). J Biol Chem (2006) 1.04
Functional analysis of the post-transcriptional regulator RsmA reveals a novel RNA-binding site. J Mol Biol (2005) 1.03
HIV-1 capsid undergoes coupled binding and isomerization by the nuclear pore protein NUP358. Retrovirology (2013) 1.01
NMR structure of the alpha-hemoglobin stabilizing protein: insights into conformational heterogeneity and binding. J Biol Chem (2004) 0.99
Electrostatic interactions contribute to reduced heat capacity change of unfolding in a thermophilic ribosomal protein l30e. J Mol Biol (2005) 0.97
The structure of the FYR domain of transforming growth factor beta regulator 1. Protein Sci (2010) 0.95
An ensemble view of thrombin allostery. Biol Chem (2012) 0.94
Crystal structures of engrailed homeodomain mutants: implications for stability and dynamics. J Biol Chem (2003) 0.94
The folding mechanism of BBL: Plasticity of transition-state structure observed within an ultrafast folding protein family. J Mol Biol (2009) 0.92
Crystallization and preliminary crystallographic analysis of an acylphosphatase from the hyperthermophilic archaeon Pyrococcus horikoshii. Acta Crystallogr D Biol Crystallogr (2004) 0.91
The general definition of the p97/valosin-containing protein (VCP)-interacting motif (VIM) delineates a new family of p97 cofactors. J Biol Chem (2011) 0.90
Solution structure of the HPV-16 E2 DNA binding domain, a transcriptional regulator with a dimeric beta-barrel fold. J Biomol NMR (2004) 0.90
The solution structure of the ZnF UBP domain of USP33/VDU1. Protein Sci (2007) 0.90
Binding of EMSY to HP1beta: implications for recruitment of HP1beta and BS69. EMBO Rep (2005) 0.90
Molecular basis of the interactions between the p73 N terminus and p300: effects on transactivation and modulation by phosphorylation. Proc Natl Acad Sci U S A (2009) 0.89
Structural distortion of p53 by the mutation R249S and its rescue by a designed peptide: implications for "mutant conformation". J Mol Biol (2004) 0.89
Thermodynamic origins of protein folding, allostery, and capsid formation in the human hepatitis B virus core protein. Proc Natl Acad Sci U S A (2013) 0.89
VHL mutations linked to type 2C von Hippel-Lindau disease cause extensive structural perturbations in pVHL. J Biol Chem (2009) 0.88
The V86M mutation in HIV-1 capsid confers resistance to TRIM5α by abrogation of cyclophilin A-dependent restriction and enhancement of viral nuclear import. Retrovirology (2013) 0.87
Solution structure and thermal stability of ribosomal protein L30e from hyperthermophilic archaeon Thermococcus celer. Protein Sci (2003) 0.87
Peptide mimics of the Bowman-Birk inhibitor reactive site loop. Biopolymers (2002) 0.87
Crystal structure of ribosomal protein L30e from the extreme thermophile Thermococcus celer: thermal stability and RNA binding. Biochemistry (2003) 0.86
Crystal structure of a hyperthermophilic archaeal acylphosphatase from Pyrococcus horikoshii--structural insights into enzymatic catalysis, thermostability, and dimerization. Biochemistry (2005) 0.86
An fMRI investigation of emotional processing of body shape in bulimia nervosa. Int J Eat Disord (2011) 0.85
Brain potentials elicited by prose-embedded linguistic anomalies. Mem Cognit (2002) 0.84
Structural basis of p63α SAM domain mutants involved in AEC syndrome. FEBS J (2011) 0.84
Stabilising the DNA-binding domain of p53 by rational design of its hydrophobic core. Protein Eng Des Sel (2009) 0.84
SRF phosphorylation by glycogen synthase kinase-3 promotes axon growth in hippocampal neurons. J Neurosci (2014) 0.83
An fMRI study of sex differences in brain activation during object naming. Cortex (2008) 0.83
Structure of human MDM4 N-terminal domain bound to a single-domain antibody. J Mol Biol (2008) 0.83