Published in FASEB J on August 15, 2008
The major component in schistosome eggs responsible for conditioning dendritic cells for Th2 polarization is a T2 ribonuclease (omega-1). J Exp Med (2009) 2.34
Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responses. J Exp Med (2009) 2.24
The Extracellular Vesicles of the Helminth Pathogen, Fasciola hepatica: Biogenesis Pathways and Cargo Molecules Involved in Parasite Pathogenesis. Mol Cell Proteomics (2015) 2.10
Helminth-derived immunomodulators: can understanding the worm produce the pill? Nat Rev Immunol (2010) 1.66
An integrated transcriptomics and proteomics analysis of the secretome of the helminth pathogen Fasciola hepatica: proteins associated with invasion and infection of the mammalian host. Mol Cell Proteomics (2009) 1.63
Rapid host defense against Aspergillus fumigatus involves alveolar macrophages with a predominance of alternatively activated phenotype. PLoS One (2011) 1.21
Parasitic helminths: new weapons against immunological disorders. J Biomed Biotechnol (2010) 1.13
Major secretory antigens of the helminth Fasciola hepatica activate a suppressive dendritic cell phenotype that attenuates Th17 cells but fails to activate Th2 immune responses. Infect Immun (2009) 1.11
A family of helminth molecules that modulate innate cell responses via molecular mimicry of host antimicrobial peptides. PLoS Pathog (2011) 1.10
The Fasciola hepatica genome: gene duplication and polymorphism reveals adaptation to the host environment and the capacity for rapid evolution. Genome Biol (2015) 1.09
Th2 responses in schistosomiasis. Semin Immunopathol (2012) 1.04
Novel roles of peroxiredoxins in inflammation, cancer and innate immunity. J Clin Biochem Nutr (2012) 1.04
Helminth infection in populations undergoing epidemiological transition: a friend or foe? Semin Immunopathol (2012) 1.01
Peroxiredoxins in parasites. Antioxid Redox Signal (2012) 1.01
Glycoconjugates in host-helminth interactions. Front Immunol (2013) 1.01
Functional impairment of human myeloid dendritic cells during Schistosoma haematobium infection. PLoS Negl Trop Dis (2010) 0.97
Progressive visceral leishmaniasis is driven by dominant parasite-induced STAT6 activation and STAT6-dependent host arginase 1 expression. PLoS Pathog (2012) 0.97
Survey of transcripts expressed by the invasive juvenile stage of the liver fluke Fasciola hepatica. BMC Genomics (2010) 0.93
Fasciola hepatica vaccine: we may not be there yet but we're on the right road. Vet Parasitol (2015) 0.92
Evolutionary roots of arginase expression and regulation. Front Immunol (2014) 0.92
A deep exploration of the transcriptome and "excretory/secretory" proteome of adult Fascioloides magna. Mol Cell Proteomics (2012) 0.91
Cysteine peptidases as schistosomiasis vaccines with inbuilt adjuvanticity. PLoS One (2014) 0.90
C-type lectins on macrophages participate in the immunomodulatory response to Fasciola hepatica products. Immunology (2011) 0.88
Interleukin-33 and alveolar macrophages contribute to the mechanisms underlying the exacerbation of IgE-mediated airway inflammation and remodelling in mice. Immunology (2013) 0.87
Cathelicidin-like helminth defence molecules (HDMs): absence of cytotoxic, anti-microbial and anti-protozoan activities imply a specific adaptation to immune modulation. PLoS Negl Trop Dis (2013) 0.87
Fasciola hepatica fatty acid binding protein induces the alternative activation of human macrophages. Infect Immun (2014) 0.86
Fasciola hepatica fatty acid binding protein inhibits TLR4 activation and suppresses the inflammatory cytokines induced by lipopolysaccharide in vitro and in vivo. J Immunol (2015) 0.86
Toxoplasma gondii peroxiredoxin promotes altered macrophage function, caspase-1-dependent IL-1β secretion enhances parasite replication. Vet Res (2011) 0.86
Interface Molecules of Angiostrongylus cantonensis: Their Role in Parasite Survival and Modulation of Host Defenses. Int J Inflam (2012) 0.85
Immunoregulation by Taenia crassiceps and its antigens. Biomed Res Int (2012) 0.84
A study of prevalence of intestinal worm infestation and efficacy of anthelminthic drugs. Med J Armed Forces India (2014) 0.84
Multiple Roles of Peroxiredoxins in Inflammation. Mol Cells (2016) 0.83
Secreted proteins from the helminth Fasciola hepatica inhibit the initiation of autoreactive T cell responses and prevent diabetes in the NOD mouse. PLoS One (2014) 0.83
Transcriptional analysis identifies key genes involved in metabolism, fibrosis/tissue repair and the immune response against Fasciola hepatica in sheep liver. Parasit Vectors (2015) 0.83
Induction of Protective Immune Responses Against Schistosomiasis haematobium in Hamsters and Mice Using Cysteine Peptidase-Based Vaccine. Front Immunol (2015) 0.83
Helminth defence molecules-immunomodulators designed by parasites! Front Microbiol (2013) 0.80
Transcriptome profiling of the fifth-stage larvae of Angiostrongylus cantonensis by next-generation sequencing. Parasitol Res (2013) 0.78
Th1 and Th2 cytokine gene expression in primary infection and vaccination against Fasciola gigantica in buffaloes by real-time PCR. Parasitol Res (2013) 0.78
Schistosome: its benefit and harm in patients suffering from concomitant diseases. J Biomed Biotechnol (2011) 0.78
A prospective view of animal and human Fasciolosis. Parasite Immunol (2016) 0.77
Comparative proteomics analysis of mice lymphocytes in early stages of infection by different strains of rabies virus. Indian J Virol (2012) 0.77
Characterization of a Thioredoxin-1 Gene from Taenia solium and Its Encoding Product. Biomed Res Int (2015) 0.76
A mucin-like peptide from Fasciola hepatica induces parasite-specific Th1-type cell immunity. Parasitol Res (2015) 0.76
Tegument Glycoproteins and Cathepsins of Newly Excysted Juvenile Fasciola hepatica Carry Mannosidic and Paucimannosidic N-glycans. PLoS Negl Trop Dis (2016) 0.76
Thalidomide inhibits alternative activation of macrophages in vivo and in vitro: a potential mechanism of anti-asthmatic effect of thalidomide. PLoS One (2015) 0.76
Adjuvant-enhanced antibody and cellular responses to inclusion bodies expressing FhSAP2 correlates with protection of mice to Fasciola hepatica. Exp Parasitol (2015) 0.75
PD-L2 negatively regulates Th1-mediated immunopathology during Fasciola hepatica infection. Oncotarget (2016) 0.75
A Proteomic Investigation of Hepatic Resistance to Ascaris in a Murine Model. PLoS Negl Trop Dis (2016) 0.75
Fasciola hepatica reinfection potentiates a mixed Th1/Th2/Th17/Treg response and correlates with the clinical phenotypes of anemia. PLoS One (2017) 0.75
Immune modulation by helminth parasites of ruminants: implications for vaccine development and host immune competence. Parasite (2014) 0.75
Transcriptome profiling of gene expression during immunisation trial against Fasciola hepatica: identification of genes and pathways involved in conferring immunoprotection in a murine model. BMC Infect Dis (2017) 0.75
Recombinant Fasciola hepatica fatty acid binding protein suppresses toll-like receptor stimulation in response to multiple bacterial ligands. Sci Rep (2017) 0.75
Heme-Oxygenase-1 Expression Contributes to the Immunoregulation Induced by Fasciola hepatica and Promotes Infection. Front Immunol (2017) 0.75
Proteomic analysis of Fasciola hepatica excretory and secretory products (FhESPs) involved in interacting with host PBMCs and cytokines by shotgun LC-MS/MS. Parasitol Res (2016) 0.75
Alternative activation of macrophages. Nat Rev Immunol (2003) 27.53
Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol (2002) 17.85
Structure, mechanism and regulation of peroxiredoxins. Trends Biochem Sci (2003) 8.84
Alternative macrophage activation is essential for survival during schistosomiasis and downmodulates T helper 1 responses and immunopathology. Immunity (2004) 6.46
Altered macrophage differentiation and immune dysfunction in tumor development. J Clin Invest (2007) 6.31
Acidic mammalian chitinase in asthmatic Th2 inflammation and IL-13 pathway activation. Science (2004) 6.28
Downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni. J Exp Med (1991) 5.04
Biochemical and functional characterization of three activated macrophage populations. J Leukoc Biol (2006) 4.87
Helminth parasites--masters of regulation. Immunol Rev (2004) 4.54
Memory T(H)2 cells induce alternatively activated macrophages to mediate protection against nematode parasites. Nat Med (2006) 4.16
Differential expression of FIZZ1 and Ym1 in alternatively versus classically activated macrophages. J Leukoc Biol (2002) 3.89
Egg deposition is the major stimulus for the production of Th2 cytokines in murine schistosomiasis mansoni. J Immunol (1991) 3.65
Peroxiredoxins. Biol Chem (2002) 3.61
Removal of endotoxin from protein solutions by phase separation using Triton X-114. J Immunol Methods (1990) 3.48
IL-4 dependent alternatively-activated macrophages have a distinctive in vivo gene expression phenotype. BMC Immunol (2002) 3.44
Interleukin-13-regulated M2 macrophages in combination with myeloid suppressor cells block immune surveillance against metastasis. Cancer Res (2005) 2.73
Alternatively activated macrophages in helminth infections. Curr Opin Immunol (2007) 2.41
2-Cys peroxiredoxin function in intracellular signal transduction: therapeutic implications. Trends Mol Med (2005) 2.02
Alternatively activated macrophages during parasite infections. Trends Parasitol (2004) 2.01
Th2 response polarization during infection with the helminth parasite Schistosoma mansoni. Immunol Rev (2004) 1.88
Reactive oxygen species and 12/15-lipoxygenase contribute to the antiproliferative capacity of alternatively activated myeloid cells elicited during helminth infection. J Immunol (2005) 1.86
A schistosome-expressed immunomodulatory glycoconjugate expands peritoneal Gr1(+) macrophages that suppress naive CD4(+) T cell proliferation via an IFN-gamma and nitric oxide-dependent mechanism. J Immunol (2001) 1.78
The PAG gene product, a stress-induced protein with antioxidant properties, is an Abl SH3-binding protein and a physiological inhibitor of c-Abl tyrosine kinase activity. Genes Dev (1997) 1.72
Immunology of parasitic helminth infections. Infect Immun (2002) 1.62
Proteomic analysis of Schistosoma mansoni egg secretions. Mol Biochem Parasitol (2007) 1.62
A Brugia malayi homolog of macrophage migration inhibitory factor reveals an important link between macrophages and eosinophil recruitment during nematode infection. J Immunol (2001) 1.60
Thioredoxin peroxidase secreted by Fasciola hepatica induces the alternative activation of macrophages. Infect Immun (2005) 1.59
Biochemical characterization of 2-Cys peroxiredoxins from Schistosoma mansoni. J Biol Chem (2004) 1.50
Helminth anti-oxidant enzymes: a protective mechanism against host oxidants? Parasitol Today (1988) 1.44
Genetic characterization of the murine Ym1 gene and identification of a cluster of highly homologous genes. Genomics (1998) 1.37
Cathepsin L1, the major protease involved in liver fluke (Fasciola hepatica) virulence: propetide cleavage sites and autoactivation of the zymogen secreted from gastrodermal cells. J Biol Chem (2004) 1.36
Vaccines against the zoonotic trematodes Schistosoma japonicum, Fasciola hepatica and Fasciola gigantica. Parasitology (2006) 1.35
Simvastatin promotes Th2-type responses through the induction of the chitinase family member Ym1 in dendritic cells. Proc Natl Acad Sci U S A (2006) 1.33
Antigen-presenting cells recruited by Brugia malayi induce Th2 differentiation of naïve CD4(+) T cells. Eur J Immunol (2000) 1.33
Fasciola hepatica infection downregulates Th1 responses in mice. Parasite Immunol (2000) 1.32
Transient expression of Ym1, a heparin-binding lectin, during developmental hematopoiesis and inflammation. J Leukoc Biol (2002) 1.28
Pag, a putative tumor suppressor, interacts with the Myc Box II domain of c-Myc and selectively alters its biological function and target gene expression. J Biol Chem (2002) 1.20
Peroxiredoxin 1 interacts with androgen receptor and enhances its transactivation. Cancer Res (2007) 1.15
Peroxidoxins: a new antioxidant family. Parasitol Today (1998) 1.13
Peroxiredoxin-I is an autoimmunogenic tumor antigen in non-small cell lung cancer. FEBS Lett (2005) 1.12
Antioxidant enzyme families in parasitic nematodes. Mol Biochem Parasitol (2001) 1.11
The immunomodulatory glycan LNFPIII initiates alternative activation of murine macrophages in vivo. Immunology (2008) 1.08
The role of pulmonary cellular reactions in the resistance of vaccinated mice to Schistosoma mansoni. Parasite Immunol (1986) 1.05
Kupffer cells from Schistosoma mansoni-infected mice participate in the prompt type 2 differentiation of hepatic T cells in response to worm antigens. J Immunol (1999) 1.05
Schistosome infection stimulates host CD4(+) T helper cell and B-cell responses against a novel egg antigen, thioredoxin peroxidase. Infect Immun (2001) 1.04
Peroxiredoxin-4 interacts with and regulates the thromboxane A(2) receptor. FEBS Lett (2007) 0.98
TNF is essential for the cell-mediated protective immunity induced by the radiation-attenuated schistosome vaccine. J Immunol (1999) 0.95
2-Cys peroxiredoxins from Schistosoma japonicum: the expression profile and localization in the life cycle. Mol Biochem Parasitol (2006) 0.95
Biochemical characterisation of the recombinant peroxiredoxin (FhePrx) of the liver fluke, Fasciola hepatica. FEBS Lett (2006) 0.94
Helminths at mucosal barriers--interaction with the immune system. Adv Drug Deliv Rev (2004) 0.80
Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins. Immunity (2005) 6.21
The genome of the blood fluke Schistosoma mansoni. Nature (2009) 5.94
Dectin-1 mediates the biological effects of beta-glucans. J Exp Med (2003) 5.82
Human dectin-1 deficiency and mucocutaneous fungal infections. N Engl J Med (2009) 5.27
Dectin-1 is a major beta-glucan receptor on macrophages. J Exp Med (2002) 4.87
Immune sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptors. J Clin Invest (2006) 4.45
The beta-glucan receptor dectin-1 recognizes specific morphologies of Aspergillus fumigatus. PLoS Pathog (2005) 3.13
The macrophage mannose receptor induces IL-17 in response to Candida albicans. Cell Host Microbe (2009) 3.07
Identification of oxadiazoles as new drug leads for the control of schistosomiasis. Nat Med (2008) 2.90
Dectin-1 uses novel mechanisms for yeast phagocytosis in macrophages. Blood (2004) 2.84
A novel selective positive allosteric modulator of metabotropic glutamate receptor subtype 5 has in vivo activity and antipsychotic-like effects in rat behavioral models. J Pharmacol Exp Ther (2004) 2.83
Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors. Eur J Immunol (2008) 2.62
Discovery of positive allosteric modulators for the metabotropic glutamate receptor subtype 5 from a series of N-(1,3-diphenyl-1H- pyrazol-5-yl)benzamides that potentiate receptor function in vivo. J Med Chem (2004) 2.46
Thioredoxin glutathione reductase from Schistosoma mansoni: an essential parasite enzyme and a key drug target. PLoS Med (2007) 2.39
Dectin-1 expression and function are enhanced on alternatively activated and GM-CSF-treated macrophages and are negatively regulated by IL-10, dexamethasone, and lipopolysaccharide. J Immunol (2003) 2.38
A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5. Mol Pharmacol (2003) 2.27
Reduced cardiac hypertrophy in toll-like receptor 4-deficient mice following pressure overload. Cardiovasc Res (2005) 2.24
A novel selective allosteric modulator potentiates the activity of native metabotropic glutamate receptor subtype 5 in rat forebrain. J Pharmacol Exp Ther (2004) 2.17
Challenges in the development of mGluR5 positive allosteric modulators: the discovery of CPPHA. Bioorg Med Chem Lett (2006) 2.17
Allosteric modulation of group III metabotropic glutamate receptor 4: a potential approach to Parkinson's disease treatment. Proc Natl Acad Sci U S A (2003) 1.98
Activation of Toll-like receptor 4 signaling contributes to hippocampal neuronal death following global cerebral ischemia/reperfusion. J Neuroimmunol (2007) 1.84
The role of SIGNR1 and the beta-glucan receptor (dectin-1) in the nonopsonic recognition of yeast by specific macrophages. J Immunol (2004) 1.82
The human beta-glucan receptor is widely expressed and functionally equivalent to murine Dectin-1 on primary cells. Eur J Immunol (2005) 1.80
Progress towards validating the NMDA receptor hypofunction hypothesis of schizophrenia. Curr Top Med Chem (2006) 1.77
Dectin-1 interaction with Mycobacterium tuberculosis leads to enhanced IL-12p40 production by splenic dendritic cells. J Immunol (2007) 1.77
Protection against myocardial ischemia/reperfusion injury in TLR4-deficient mice is mediated through a phosphoinositide 3-kinase-dependent mechanism. J Immunol (2007) 1.75
Lipopolysaccharide-induced myocardial protection against ischaemia/reperfusion injury is mediated through a PI3K/Akt-dependent mechanism. Cardiovasc Res (2008) 1.70
Diagnosis of human fasciolosis in the Gilan province of Northern Iran: application of cathepsin L-ELISA. Diagn Microbiol Infect Dis (2002) 1.70
Syk-dependent ERK activation regulates IL-2 and IL-10 production by DC stimulated with zymosan. Eur J Immunol (2007) 1.69
Modulating Toll-like receptor mediated signaling by (1-->3)-beta-D-glucan rapidly induces cardioprotection. Cardiovasc Res (2004) 1.69
Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase. Proc Natl Acad Sci U S A (2009) 1.63
An integrated transcriptomics and proteomics analysis of the secretome of the helminth pathogen Fasciola hepatica: proteins associated with invasion and infection of the mammalian host. Mol Cell Proteomics (2009) 1.63
Proteomic analysis of Schistosoma mansoni egg secretions. Mol Biochem Parasitol (2007) 1.62
Cholesterol binding, efflux, and a PDZ-interacting domain of scavenger receptor-BI mediate HDL-initiated signaling. J Clin Invest (2005) 1.62
Thioredoxin peroxidase secreted by Fasciola hepatica induces the alternative activation of macrophages. Infect Immun (2005) 1.59
The disulfide redox system of Schistosoma mansoni and the importance of a multifunctional enzyme, thioredoxin glutathione reductase. Mol Biochem Parasitol (2002) 1.59
Quantitative high-throughput screen identifies inhibitors of the Schistosoma mansoni redox cascade. PLoS Negl Trop Dis (2008) 1.58
Identification and characterization of a novel human myeloid inhibitory C-type lectin-like receptor (MICL) that is predominantly expressed on granulocytes and monocytes. J Biol Chem (2004) 1.57
Zoonotic helminth infections with particular emphasis on fasciolosis and other trematodiases. Philos Trans R Soc Lond B Biol Sci (2009) 1.56
The induction of inflammation by dectin-1 in vivo is dependent on myeloid cell programming and the progression of phagocytosis. J Immunol (2008) 1.56
NF-kappaB activation is required for the development of cardiac hypertrophy in vivo. Am J Physiol Heart Circ Physiol (2004) 1.54
Differential high-affinity interaction of dectin-1 with natural or synthetic glucans is dependent upon primary structure and is influenced by polymer chain length and side-chain branching. J Pharmacol Exp Ther (2008) 1.52
Biochemical characterization of 2-Cys peroxiredoxins from Schistosoma mansoni. J Biol Chem (2004) 1.50
Dendritic cell interaction with Candida albicans critically depends on N-linked mannan. J Biol Chem (2008) 1.50
Class B scavenger receptor-mediated intestinal absorption of dietary beta-carotene and cholesterol. Biochemistry (2005) 1.48
Reciprocal regulation of IL-23 and IL-12 following co-activation of Dectin-1 and TLR signaling pathways. Eur J Immunol (2009) 1.44
Inhibition of Schistosoma mansoni thioredoxin-glutathione reductase by auranofin: structural and kinetic aspects. J Biol Chem (2009) 1.43
Soluble Dectin-1 as a tool to detect beta-glucans. J Immunol Methods (2006) 1.43
Preconditioning with a TLR2 specific ligand increases resistance to cerebral ischemia/reperfusion injury. J Neuroimmunol (2008) 1.41
Dectin-1 promotes fungicidal activity of human neutrophils. Eur J Immunol (2007) 1.41
TLR2 ligands induce cardioprotection against ischaemia/reperfusion injury through a PI3K/Akt-dependent mechanism. Cardiovasc Res (2010) 1.40
Differential roles of TLR2 and TLR4 in acute focal cerebral ischemia/reperfusion injury in mice. Brain Res (2009) 1.38
Scavenger receptor BI: a scavenger receptor with a mission to transport high density lipoprotein lipids. Curr Opin Lipidol (2004) 1.37
Cathepsin L1, the major protease involved in liver fluke (Fasciola hepatica) virulence: propetide cleavage sites and autoactivation of the zymogen secreted from gastrodermal cells. J Biol Chem (2004) 1.36
Oral delivery and gastrointestinal absorption of soluble glucans stimulate increased resistance to infectious challenge. J Pharmacol Exp Ther (2005) 1.34
Redox balance mechanisms in Schistosoma mansoni rely on peroxiredoxins and albumin and implicate peroxiredoxins as novel drug targets. J Biol Chem (2006) 1.28
The CD5 ectodomain interacts with conserved fungal cell wall components and protects from zymosan-induced septic shock-like syndrome. Proc Natl Acad Sci U S A (2009) 1.28
The silencing of cysteine proteases in Fasciola hepatica newly excysted juveniles using RNA interference reduces gut penetration. Int J Parasitol (2007) 1.26
Topographical characterization of cone photoreceptors and the area centralis of the canine retina. Mol Vis (2008) 1.23
Human monocyte scavenger receptors are pattern recognition receptors for (1-->3)-beta-D-glucans. J Leukoc Biol (2002) 1.23
Regulation of cytosolic phospholipase A2 activation and cyclooxygenase 2 expression in macrophages by the beta-glucan receptor. J Biol Chem (2006) 1.23
An atlas for Schistosoma mansoni organs and life-cycle stages using cell type-specific markers and confocal microscopy. PLoS Negl Trop Dis (2011) 1.23
The Fasciola hepatica tegumental antigen suppresses dendritic cell maturation and function. Infect Immun (2009) 1.22
TLR2 ligands attenuate cardiac dysfunction in polymicrobial sepsis via a phosphoinositide 3-kinase-dependent mechanism. Am J Physiol Heart Circ Physiol (2010) 1.22
Plasmodium falciparum neutral aminopeptidases: new targets for anti-malarials. Trends Biochem Sci (2009) 1.21
Expression of functionally different dectin-1 isoforms by murine macrophages. J Immunol (2006) 1.21
Cleavage of hemoglobin by hookworm cathepsin D aspartic proteases and its potential contribution to host specificity. FASEB J (2002) 1.20
Structural and functional relationships in the virulence-associated cathepsin L proteases of the parasitic liver fluke, Fasciola hepatica. J Biol Chem (2007) 1.19
RNA interference targeting leucine aminopeptidase blocks hatching of Schistosoma mansoni eggs. Mol Biochem Parasitol (2009) 1.18
Proteomics and phylogenetic analysis of the cathepsin L protease family of the helminth pathogen Fasciola hepatica: expansion of a repertoire of virulence-associated factors. Mol Cell Proteomics (2008) 1.18
Attenuation of cardiac hypertrophy by inhibiting both mTOR and NFkappaB activation in vivo. Free Radic Biol Med (2005) 1.17
Helminth pathogen cathepsin proteases: it's a family affair. Trends Biochem Sci (2008) 1.16
Characterization of the Plasmodium falciparum M17 leucyl aminopeptidase. A protease involved in amino acid regulation with potential for antimalarial drug development. J Biol Chem (2006) 1.15
In vivo modulation of HDL phospholipid has opposing effects on SR-BI- and ABCA1-mediated cholesterol efflux. J Lipid Res (2003) 1.14
Glucan phosphate attenuates cardiac dysfunction and inhibits cardiac MIF expression and apoptosis in septic mice. Am J Physiol Heart Circ Physiol (2006) 1.14
Blocking the MyD88-dependent pathway protects the myocardium from ischemia/reperfusion injury in rat hearts. Biochem Biophys Res Commun (2005) 1.13
Molecular and enzymatic characterisation of Schistosoma mansoni thioredoxin. Int J Parasitol (2002) 1.11
Major secretory antigens of the helminth Fasciola hepatica activate a suppressive dendritic cell phenotype that attenuates Th17 cells but fails to activate Th2 immune responses. Infect Immun (2009) 1.11
Trained immunity or tolerance: opposing functional programs induced in human monocytes after engagement of various pattern recognition receptors. Clin Vaccine Immunol (2014) 1.11
A family of helminth molecules that modulate innate cell responses via molecular mimicry of host antimicrobial peptides. PLoS Pathog (2011) 1.10
Scavenger receptor class a plays a central role in mediating mortality and the development of the pro-inflammatory phenotype in polymicrobial sepsis. PLoS Pathog (2012) 1.10
Helminth cysteine proteases inhibit TRIF-dependent activation of macrophages via degradation of TLR3. J Biol Chem (2009) 1.10
Leucine aminopeptidase of the human blood flukes, Schistosoma mansoni and Schistosoma japonicum. Int J Parasitol (2004) 1.09
Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidases. Proc Natl Acad Sci U S A (2010) 1.09
Overexpression of leucyl aminopeptidase in Plasmodium falciparum parasites. Target for the antimalarial activity of bestatin. J Biol Chem (2005) 1.08