Published in PLoS Pathog on May 12, 2011
The Extracellular Vesicles of the Helminth Pathogen, Fasciola hepatica: Biogenesis Pathways and Cargo Molecules Involved in Parasite Pathogenesis. Mol Cell Proteomics (2015) 2.10
Infection with the carcinogenic liver fluke Opisthorchis viverrini modifies intestinal and biliary microbiome. FASEB J (2013) 1.24
The Opisthorchis viverrini genome provides insights into life in the bile duct. Nat Commun (2014) 1.01
Microvesicles and intercellular communication in the context of parasitism. Front Cell Infect Microbiol (2013) 0.97
Fasciola hepatica vaccine: we may not be there yet but we're on the right road. Vet Parasitol (2015) 0.92
The Role of Extracellular Vesicles in Modulating the Host Immune Response during Parasitic Infections. Front Immunol (2014) 0.91
Circulating microbial products and acute phase proteins as markers of pathogenesis in lymphatic filarial disease. PLoS Pathog (2012) 0.91
A research agenda for helminth diseases of humans: basic research and enabling technologies to support control and elimination of helminthiases. PLoS Negl Trop Dis (2012) 0.91
Regulation of the host immune system by helminth parasites. J Allergy Clin Immunol (2016) 0.91
Cathelicidin-like helminth defence molecules (HDMs): absence of cytotoxic, anti-microbial and anti-protozoan activities imply a specific adaptation to immune modulation. PLoS Negl Trop Dis (2013) 0.87
Fasciola hepatica fatty acid binding protein induces the alternative activation of human macrophages. Infect Immun (2014) 0.86
Evidence of microbial translocation associated with perturbations in T cell and antigen-presenting cell homeostasis in hookworm infections. PLoS Negl Trop Dis (2012) 0.86
The MF6p/FhHDM-1 major antigen secreted by the trematode parasite Fasciola hepatica is a heme-binding protein. J Biol Chem (2013) 0.84
Vitamin D status is not associated with inflammatory cytokine levels during experimental human endotoxaemia. Clin Exp Immunol (2013) 0.83
Transcriptional analysis identifies key genes involved in metabolism, fibrosis/tissue repair and the immune response against Fasciola hepatica in sheep liver. Parasit Vectors (2015) 0.83
Fasciola hepatica Kunitz type molecule decreases dendritic cell activation and their ability to induce inflammatory responses. PLoS One (2014) 0.83
Helminth induced suppression of macrophage activation is correlated with inhibition of calcium channel activity. PLoS One (2014) 0.81
Chronic filarial infection provides protection against bacterial sepsis by functionally reprogramming macrophages. PLoS Pathog (2015) 0.81
Helminths and their implication in sepsis - a new branch of their immunomodulatory behaviour? Pathog Dis (2013) 0.81
Helminth defence molecules-immunomodulators designed by parasites! Front Microbiol (2013) 0.80
Defense peptides secreted by helminth pathogens: antimicrobial and/or immunomodulator molecules? Front Immunol (2012) 0.77
A parasite-derived 68-mer peptide ameliorates autoimmune disease in murine models of Type 1 diabetes and multiple sclerosis. Sci Rep (2016) 0.75
The Echinococcus canadensis (G7) genome: a key knowledge of parasitic platyhelminth human diseases. BMC Genomics (2017) 0.75
Usefulness of ELISA Methods for Assessing LPS Interactions with Proteins and Peptides. PLoS One (2016) 0.75
Immune modulation by helminth parasites of ruminants: implications for vaccine development and host immune competence. Parasite (2014) 0.75
Escherichia coli-induced immune paralysis is not exacerbated during chronic filarial infection. Immunology (2015) 0.75
Helminth Immunomodulation in Autoimmune Disease. Front Immunol (2017) 0.75
Proteomic analysis of Fasciola hepatica excretory and secretory products (FhESPs) involved in interacting with host PBMCs and cytokines by shotgun LC-MS/MS. Parasitol Res (2016) 0.75
Basic local alignment search tool. J Mol Biol (1990) 659.07
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res (1994) 392.47
Improved prediction of signal peptides: SignalP 3.0. J Mol Biol (2004) 48.40
Protein secondary structure prediction based on position-specific scoring matrices. J Mol Biol (1999) 33.07
InterProScan--an integration platform for the signature-recognition methods in InterPro. Bioinformatics (2001) 28.35
MEGA: Molecular Evolutionary Genetics Analysis software for microcomputers. Comput Appl Biosci (1994) 28.25
Monocyte and macrophage heterogeneity. Nat Rev Immunol (2005) 24.36
Size-distribution analysis of macromolecules by sedimentation velocity ultracentrifugation and lamm equation modeling. Biophys J (2000) 21.93
Recognition of microorganisms and activation of the immune response. Nature (2007) 12.99
Estimation of protein secondary structure from circular dichroism spectra: comparison of CONTIN, SELCON, and CDSSTR methods with an expanded reference set. Anal Biochem (2000) 11.10
Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies. Nat Biotechnol (2006) 10.15
Peptide antibiotics and their role in innate immunity. Annu Rev Immunol (1995) 6.81
Peptide antibiotics. Lancet (1997) 6.76
Alternative macrophage activation is essential for survival during schistosomiasis and downmodulates T helper 1 responses and immunopathology. Immunity (2004) 6.46
Size-distribution analysis of proteins by analytical ultracentrifugation: strategies and application to model systems. Biophys J (2002) 5.20
Lethal toxicity of lipopolysaccharide and tumor necrosis factor in normal and D-galactosamine-treated mice. J Exp Med (1987) 4.63
The role of antimicrobial peptides in animal defenses. Proc Natl Acad Sci U S A (2000) 3.52
Analyzing protein circular dichroism spectra for accurate secondary structures. Proteins (1999) 3.26
The human gene FALL39 and processing of the cathelin precursor to the antibacterial peptide LL-37 in granulocytes. Eur J Biochem (1996) 3.08
LL-37, the only human member of the cathelicidin family of antimicrobial peptides. Biochim Biophys Acta (2006) 3.05
FALL-39, a putative human peptide antibiotic, is cysteine-free and expressed in bone marrow and testis. Proc Natl Acad Sci U S A (1995) 2.89
Human CAP18: a novel antimicrobial lipopolysaccharide-binding protein. Infect Immun (1995) 2.87
How we detect microbes and respond to them: the Toll-like receptors and their transducers. J Leukoc Biol (2003) 2.83
Alternatively activated macrophages in helminth infections. Curr Opin Immunol (2007) 2.41
Crystal structure of an endotoxin-neutralizing protein from the horseshoe crab, Limulus anti-LPS factor, at 1.5 A resolution. EMBO J (1993) 2.15
Mast cells disrupt epithelial barrier function during enteric nematode infection. Proc Natl Acad Sci U S A (2003) 1.92
Antimicrobial peptides and the skin immune defense system. J Allergy Clin Immunol (2008) 1.85
Cationic host defence peptides: innate immune regulatory peptides as a novel approach for treating infections. Cell Mol Life Sci (2007) 1.79
Immunomodulatory activities of small host defense peptides. Antimicrob Agents Chemother (2005) 1.67
Human defensins and LL-37 in mucosal immunity. J Leukoc Biol (2009) 1.67
NMR structure of the cathelicidin-derived human antimicrobial peptide LL-37 in dodecylphosphocholine micelles. Biochemistry (2008) 1.65
An integrated transcriptomics and proteomics analysis of the secretome of the helminth pathogen Fasciola hepatica: proteins associated with invasion and infection of the mammalian host. Mol Cell Proteomics (2009) 1.63
Thioredoxin peroxidase secreted by Fasciola hepatica induces the alternative activation of macrophages. Infect Immun (2005) 1.59
Self-association of human apolipoprotein E3 and E4 in the presence and absence of phospholipid. J Biol Chem (2000) 1.58
Cathelicidin family of antibacterial peptides CAP18 and CAP11 inhibit the expression of TNF-alpha by blocking the binding of LPS to CD14(+) cells. J Immunol (2001) 1.52
Structural features and biological activities of the cathelicidin-derived antimicrobial peptides. Biopolymers (2000) 1.51
Alternative activation of macrophages by IL-4 impairs phagocytosis of pathogens but potentiates microbial-induced signalling and cytokine secretion. Blood (2009) 1.50
Helminth 2-Cys peroxiredoxin drives Th2 responses through a mechanism involving alternatively activated macrophages. FASEB J (2008) 1.49
Alternatively activated macrophages elicited by helminth infection can be reprogrammed to enable microbial killing. J Immunol (2009) 1.37
Innate immune responses to danger signals in systemic inflammatory response syndrome and sepsis. Scand J Immunol (2009) 1.37
Human neutrophil defensins increase neutrophil uptake of influenza A virus and bacteria and modify virus-induced respiratory burst responses. J Immunol (2007) 1.30
Defensins in innate immunity. Cell Tissue Res (2010) 1.25
Protective effects of a human 18-kilodalton cationic antimicrobial protein (CAP18)-derived peptide against murine endotoxemia. Infect Immun (1998) 1.24
Dying and necrotic neutrophils are anti-inflammatory secondary to the release of alpha-defensins. J Immunol (2009) 1.21
Structural and functional relationships in the virulence-associated cathepsin L proteases of the parasitic liver fluke, Fasciola hepatica. J Biol Chem (2007) 1.19
Proteomics and phylogenetic analysis of the cathepsin L protease family of the helminth pathogen Fasciola hepatica: expansion of a repertoire of virulence-associated factors. Mol Cell Proteomics (2008) 1.18
Leukocyte antimicrobial peptides: multifunctional effector molecules of innate immunity. J Leukoc Biol (2000) 1.18
Cathelicidins and functional analogues as antisepsis molecules. Expert Opin Ther Targets (2007) 1.16
Helminth pathogen cathepsin proteases: it's a family affair. Trends Biochem Sci (2008) 1.16
Development of novel LL-37 derived antimicrobial peptides with LPS and LTA neutralizing and antimicrobial activities for therapeutic application. Peptides (2005) 1.16
Review: Defensins and cathelicidins in lung immunity. Innate Immun (2010) 1.14
Helminth cysteine proteases inhibit TRIF-dependent activation of macrophages via degradation of TLR3. J Biol Chem (2009) 1.10
Augmentation of the lipopolysaccharide-neutralizing activities of human cathelicidin CAP18/LL-37-derived antimicrobial peptides by replacement with hydrophobic and cationic amino acid residues. Clin Diagn Lab Immunol (2002) 1.10
Antimicrobial peptides and endotoxin inhibit cytokine and nitric oxide release but amplify respiratory burst response in human and murine macrophages. Cell Microbiol (2005) 1.08
Multifunctional host defense peptides: antimicrobial peptides, the small yet big players in innate and adaptive immunity. FEBS J (2009) 1.08
The importance of pH in regulating the function of the Fasciola hepatica cathepsin L1 cysteine protease. PLoS Negl Trop Dis (2009) 1.04
Human schistosomiasis is associated with endotoxemia and Toll-like receptor 2- and 4-bearing B cells. Am J Trop Med Hyg (2011) 1.02
The Schistosoma mansoni protein Sm16/SmSLP/SmSPO-1 assembles into a nine-subunit oligomer with potential To inhibit Toll-like receptor signaling. Infect Immun (2009) 1.02
Mechanism of interaction of Salmonella and Schistosoma species. Infect Immun (1984) 1.00
Evaluation of Clonorchis sinensis recombinant 7-kilodalton antigen for serodiagnosis of clonorchiasis. Clin Diagn Lab Immunol (2004) 0.97
Secretion of an anti-inflammatory, immunomodulatory factor by Schistosomulae of Schistosoma mansoni. J Inflamm (1997) 0.96
TH1-dominant granulomatous pathology does not inhibit fibrosis or cause lethality during murine schistosomiasis. Am J Pathol (2006) 0.94
Structural basis of endotoxin recognition by natural polypeptides. Trends Microbiol (1994) 0.92
A novel role for the bactericidal/permeability increasing protein in interactions of gram-negative bacterial outer membrane blebs with dendritic cells. J Immunol (2007) 0.90
Therapeutic potential of HDPs as immunomodulatory agents. Methods Mol Biol (2010) 0.90
Strategies for the discovery and advancement of novel cationic antimicrobial peptides. Curr Top Med Chem (2010) 0.89
Modulation of lipopolysaccharide binding to human granulocytes. Immunology (1994) 0.89
Antimicrobial peptides: the LPS connection. Methods Mol Biol (2010) 0.88
High risk of bacterobilia in advanced experimental chronic fasciolosis. Acta Trop (2006) 0.87
Schistosoma intercalatum and relapses of Salmonella infection in children. Am J Trop Med Hyg (1984) 0.86
Isolation of Fasciola hepatica haemoglobin. Parasitology (1995) 0.86
Gut bacterial translocation and postoperative infections: a prospective study in schistosomotic patients. Surg Infect (Larchmt) (2005) 0.85
Increased intestinal endotoxin absorption during enteric nematode but not protozoal infections through a mast cell-mediated mechanism. Shock (2008) 0.84
Molecular cloning and expression of a functional anti-inflammatory protein, Sj16, of Schistosoma japonicum. Int J Parasitol (2008) 0.80
Role of host defense peptides of the innate immune response in sepsis. Shock (2008) 0.79
Antimicrobial cathelicidin polypeptide CAP11 suppresses the production and release of septic mediators in D-galactosamine-sensitized endotoxin shock mice. Int Immunol (2009) 0.78
Typhoid and paratyphoid fevers occurring in cases of schistosomiasis. Chin Med J (1958) 0.78
Surfactant protein A enhances the binding and deacylation of E. coli LPS by alveolar macrophages. Am J Physiol (1999) 0.77
Bovine fascioliasis in Nigeria--intercurrent parasitic and bacterial infections. Trop Anim Health Prod (1982) 0.77
Size-distribution analysis of proteins by analytical ultracentrifugation: strategies and application to model systems. Biophys J (2002) 5.20
Suppression of cytokine signaling by SOCS3: characterization of the mode of inhibition and the basis of its specificity. Immunity (2012) 2.30
The toxicogenomic multiverse: convergent recruitment of proteins into animal venoms. Annu Rev Genomics Hum Genet (2009) 2.30
Interaction between Plasmodium falciparum apical membrane antigen 1 and the rhoptry neck protein complex defines a key step in the erythrocyte invasion process of malaria parasites. J Biol Chem (2010) 1.95
Diagnosis of human fasciolosis in the Gilan province of Northern Iran: application of cathepsin L-ELISA. Diagn Microbiol Infect Dis (2002) 1.70
Inhibition of lysine biosynthesis: an evolving antibiotic strategy. Mol Biosyst (2007) 1.69
Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase. Proc Natl Acad Sci U S A (2009) 1.63
An integrated transcriptomics and proteomics analysis of the secretome of the helminth pathogen Fasciola hepatica: proteins associated with invasion and infection of the mammalian host. Mol Cell Proteomics (2009) 1.63
Structure of domain III of the blood-stage malaria vaccine candidate, Plasmodium falciparum apical membrane antigen 1 (AMA1). J Mol Biol (2002) 1.61
Thioredoxin peroxidase secreted by Fasciola hepatica induces the alternative activation of macrophages. Infect Immun (2005) 1.59
Development of a sea anemone toxin as an immunomodulator for therapy of autoimmune diseases. Toxicon (2011) 1.59
Zoonotic helminth infections with particular emphasis on fasciolosis and other trematodiases. Philos Trans R Soc Lond B Biol Sci (2009) 1.56
Helminth 2-Cys peroxiredoxin drives Th2 responses through a mechanism involving alternatively activated macrophages. FASEB J (2008) 1.49
Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels. J Biol Chem (2007) 1.48
Binding hot spot for invasion inhibitory molecules on Plasmodium falciparum apical membrane antigen 1. Infect Immun (2005) 1.48
Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis. Biochem J (2008) 1.46
The structure of SOCS3 reveals the basis of the extended SH2 domain function and identifies an unstructured insertion that regulates stability. Mol Cell (2006) 1.41
Antigen ligation triggers a conformational change within the constant domain of the alphabeta T cell receptor. Immunity (2009) 1.40
The SOCS box domain of SOCS3: structure and interaction with the elonginBC-cullin5 ubiquitin ligase. J Mol Biol (2008) 1.39
Structure and evolution of a novel dimeric enzyme from a clinically important bacterial pathogen. J Biol Chem (2008) 1.38
Structure of the Alzheimer's disease amyloid precursor protein copper binding domain. A regulator of neuronal copper homeostasis. J Biol Chem (2003) 1.38
Dihydrodipicolinate synthase from Thermotoga maritima. Biochem J (2006) 1.37
Cathepsin L1, the major protease involved in liver fluke (Fasciola hepatica) virulence: propetide cleavage sites and autoactivation of the zymogen secreted from gastrodermal cells. J Biol Chem (2004) 1.36
The structural basis for autonomous dimerization of the pre-T-cell antigen receptor. Nature (2010) 1.35
The SOCS box encodes a hierarchy of affinities for Cullin5: implications for ubiquitin ligase formation and cytokine signalling suppression. J Mol Biol (2009) 1.35
Novel conotoxins from Conus striatus and Conus kinoshitai selectively block TTX-resistant sodium channels. Biochemistry (2005) 1.31
Abundance of intrinsically unstructured proteins in P. falciparum and other apicomplexan parasite proteomes. Mol Biochem Parasitol (2006) 1.30
The silencing of cysteine proteases in Fasciola hepatica newly excysted juveniles using RNA interference reduces gut penetration. Int J Parasitol (2007) 1.26
The crystal structure of myelin oligodendrocyte glycoprotein, a key autoantigen in multiple sclerosis. Proc Natl Acad Sci U S A (2003) 1.24
The 2.1A crystal structure of the far-red fluorescent protein HcRed: inherent conformational flexibility of the chromophore. J Mol Biol (2005) 1.23
IGF-binding proteins--the pieces are falling into place. Trends Endocrinol Metab (2005) 1.22
Bass hepcidin synthesis, solution structure, antimicrobial activities and synergism, and in vivo hepatic response to bacterial infections. J Biol Chem (2004) 1.22
Age-related differences in plasma proteins: how plasma proteins change from neonates to adults. PLoS One (2011) 1.22
Plasmodium falciparum neutral aminopeptidases: new targets for anti-malarials. Trends Biochem Sci (2009) 1.21
Cleavage of hemoglobin by hookworm cathepsin D aspartic proteases and its potential contribution to host specificity. FASEB J (2002) 1.20
Structural and functional relationships in the virulence-associated cathepsin L proteases of the parasitic liver fluke, Fasciola hepatica. J Biol Chem (2007) 1.19
Proteomics and phylogenetic analysis of the cathepsin L protease family of the helminth pathogen Fasciola hepatica: expansion of a repertoire of virulence-associated factors. Mol Cell Proteomics (2008) 1.18
RNA interference targeting leucine aminopeptidase blocks hatching of Schistosoma mansoni eggs. Mol Biochem Parasitol (2009) 1.18
The SPRY domain of SSB-2 adopts a novel fold that presents conserved Par-4-binding residues. Nat Struct Mol Biol (2005) 1.18
Helminth pathogen cathepsin proteases: it's a family affair. Trends Biochem Sci (2008) 1.16
Analogs of the sea anemone potassium channel blocker ShK for the treatment of autoimmune diseases. Inflamm Allergy Drug Targets (2011) 1.15
Characterization of the Plasmodium falciparum M17 leucyl aminopeptidase. A protease involved in amino acid regulation with potential for antimalarial drug development. J Biol Chem (2006) 1.15
Secondary structure assignment of mouse SOCS3 by NMR defines the domain boundaries and identifies an unstructured insertion in the SH2 domain. FEBS J (2005) 1.14
The SPRY domain-containing SOCS box protein SPSB2 targets iNOS for proteasomal degradation. J Cell Biol (2010) 1.14
Evolution of quaternary structure in a homotetrameric enzyme. J Mol Biol (2008) 1.12
Recombinant protein vaccines against the asexual blood stages of Plasmodium falciparum. Hum Vaccin (2010) 1.11
Major secretory antigens of the helminth Fasciola hepatica activate a suppressive dendritic cell phenotype that attenuates Th17 cells but fails to activate Th2 immune responses. Infect Immun (2009) 1.11
Helminth cysteine proteases inhibit TRIF-dependent activation of macrophages via degradation of TLR3. J Biol Chem (2009) 1.10
Leucine aminopeptidase of the human blood flukes, Schistosoma mansoni and Schistosoma japonicum. Int J Parasitol (2004) 1.09
Structure, dynamics, and selectivity of the sodium channel blocker mu-conotoxin SIIIA. Biochemistry (2008) 1.09
Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidases. Proc Natl Acad Sci U S A (2010) 1.09
Ferric ions are essential for the biological activity of the hormone glycine-extended gastrin. J Biol Chem (2002) 1.09
Overexpression of leucyl aminopeptidase in Plasmodium falciparum parasites. Target for the antimalarial activity of bestatin. J Biol Chem (2005) 1.08
Solution structure of the eukaryotic pore-forming cytolysin equinatoxin II: implications for pore formation. J Mol Biol (2002) 1.08
Structures of phage-display peptides that bind to the malarial surface protein, apical membrane antigen 1, and block erythrocyte invasion. Biochemistry (2003) 1.08
Ribosome-inactivating proteins: current status and biomedical applications. Drug Discov Today (2012) 1.08
The D-diastereomer of ShK toxin selectively blocks voltage-gated K+ channels and inhibits T lymphocyte proliferation. J Biol Chem (2007) 1.07
Proteases in helminth- and allergen- induced inflammatory responses. Chem Immunol Allergy (2006) 1.06
Cathepsin F cysteine protease of the human liver fluke, Opisthorchis viverrini. PLoS Negl Trop Dis (2009) 1.06
Large-scale prediction of long disordered regions in proteins using random forests. BMC Bioinformatics (2009) 1.05
Properties of GDP-mannose pyrophosphorylase, a critical enzyme and drug target in Leishmania mexicana. J Biol Chem (2004) 1.05
The importance of pH in regulating the function of the Fasciola hepatica cathepsin L1 cysteine protease. PLoS Negl Trop Dis (2009) 1.04
SPRY domain-containing SOCS box protein 2: crystal structure and residues critical for protein binding. J Mol Biol (2009) 1.04
Structure of the analgesic mu-conotoxin KIIIA and effects on the structure and function of disulfide deletion. Biochemistry (2009) 1.04
Rapid optimization of a peptide inhibitor of malaria parasite invasion by comprehensive N-methyl scanning. J Biol Chem (2009) 1.03
Structural basis for Par-4 recognition by the SPRY domain- and SOCS box-containing proteins SPSB1, SPSB2, and SPSB4. J Mol Biol (2010) 1.03
Novel Bcl-2 homology-3 domain-like sequences identified from screening randomized peptide libraries for inhibitors of the pro-survival Bcl-2 proteins. J Biol Chem (2009) 1.03
Solution conformation, backbone dynamics and lipid interactions of the intrinsically unstructured malaria surface protein MSP2. J Mol Biol (2008) 1.03
Merozoite surface protein 2 of Plasmodium falciparum: expression, structure, dynamics, and fibril formation of the conserved N-terminal domain. Biopolymers (2007) 1.03
Specificity, affinity and efficacy of iota-conotoxin RXIA, an agonist of voltage-gated sodium channels Na(V)1.2, 1.6 and 1.7. Biochem Pharmacol (2008) 1.03
Substrate-mediated stabilization of a tetrameric drug target reveals Achilles heel in anthrax. J Biol Chem (2009) 1.03
Alpha-RgIA, a novel conotoxin that blocks the alpha9alpha10 nAChR: structure and identification of key receptor-binding residues. J Mol Biol (2008) 1.02
Mutating a critical lysine in ShK toxin alters its binding configuration in the pore-vestibule region of the voltage-gated potassium channel, Kv1.3. Biochemistry (2002) 1.02
Structure, dynamics and heparin binding of the C-terminal domain of insulin-like growth factor-binding protein-2 (IGFBP-2). J Mol Biol (2006) 1.02
Conotoxins containing nonnatural backbone spacers: cladistic-based design, chemical synthesis, and improved analgesic activity. Chem Biol (2007) 1.01
The purification, crystallization and preliminary X-ray diffraction analysis of dihydrodipicolinate synthase from Clostridium botulinum. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 1.01
Chapter 4. Peptidases of trematodes. Adv Parasitol (2009) 1.01
Immunomodulatory molecules of Fasciola hepatica: candidates for both vaccine and immunotherapeutic development. Vet Parasitol (2013) 1.01
Inhibiting dihydrodipicolinate synthase across species: towards specificity for pathogens? Bioorg Med Chem Lett (2007) 1.01
Insulin-like growth factor binding proteins: a structural perspective. Front Endocrinol (Lausanne) (2012) 1.01
Identification of phosphinate dipeptide analog inhibitors directed against the Plasmodium falciparum M17 leucine aminopeptidase as lead antimalarial compounds. J Med Chem (2007) 1.00
Fingerprinting the substrate specificity of M1 and M17 aminopeptidases of human malaria, Plasmodium falciparum. PLoS One (2012) 1.00
The trans-Golgi network GRIP-domain proteins form alpha-helical homodimers. Biochem J (2005) 1.00
Purification, crystallization and preliminary X-ray diffraction studies to near-atomic resolution of dihydrodipicolinate synthase from methicillin-resistant Staphylococcus aureus. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.99
Selective induction of the Notch ligand Jagged-1 in macrophages by soluble egg antigen from Schistosoma mansoni involves ERK signalling. Immunology (2008) 0.97
Collagenolytic activities of the major secreted cathepsin L peptidases involved in the virulence of the helminth pathogen, Fasciola hepatica. PLoS Negl Trop Dis (2011) 0.97
Potassium channel modulation by a toxin domain in matrix metalloprotease 23. J Biol Chem (2009) 0.97
The M18 aspartyl aminopeptidase of the human malaria parasite Plasmodium falciparum. J Biol Chem (2007) 0.97
Conserved main-chain peptide distortions: a proposed role for Ile203 in catalysis by dihydrodipicolinate synthase. Protein Sci (2008) 0.97
Structural basis for tetrodotoxin-resistant sodium channel binding by mu-conotoxin SmIIIA. J Biol Chem (2003) 0.97