Published in Science on August 09, 1991
A nonparametric approach for mapping quantitative trait loci. Genetics (1995) 4.49
Genetic analysis of MRL-lpr mice: relationship of the Fas apoptosis gene to disease manifestations and renal disease-modifying loci. J Exp Med (1992) 2.27
Forward and reverse genetic approaches to behavior in the mouse. Science (1994) 2.20
Mice devoid of gamma-aminobutyrate type A receptor beta3 subunit have epilepsy, cleft palate, and hypersensitive behavior. Proc Natl Acad Sci U S A (1997) 2.16
Functional expression of the murine connexin 36 gene coding for a neuron-specific gap junctional protein. J Membr Biol (2000) 1.74
Genetic analysis of type 1 diabetes using whole genome approaches. Proc Natl Acad Sci U S A (1995) 1.66
A major effect QTL determined by multiple genes in epileptic EL mice. Genome Res (2000) 1.64
Genetics of complex neurological disease: challenges and opportunities for modeling epilepsy in mice and rats. Trends Genet (2009) 1.25
Mapping murine loci for seizure response to kainic acid. Mamm Genome (1997) 1.15
A novel Akt3 mutation associated with enhanced kinase activity and seizure susceptibility in mice. Hum Mol Genet (2010) 1.11
Mapping the mouse genome: current status and future prospects. Proc Natl Acad Sci U S A (1995) 1.08
Genetic mapping of tumor susceptibility genes involved in mouse plasmacytomagenesis. Proc Natl Acad Sci U S A (1993) 1.07
Autosomal dominant nocturnal frontal-lobe epilepsy: genetic heterogeneity and evidence for a second locus at 15q24. Am J Hum Genet (1998) 1.00
Cocaine-induced seizure thresholds: quantitative trait loci detection and mapping in two populations derived from the C57BL/6 and DBA/2 mouse strains. J Pharmacol Exp Ther (2000) 0.92
Genetic and phenotypic analysis of seizure susceptibility in PL/J mice. Mamm Genome (2004) 0.92
Genetic epilepsy model derived from common inbred mouse strains. Genetics (1994) 0.92
Surgical pathology of chronic epileptic seizure disorders: experience with 63 specimens from extratemporal corticectomies, lobectomies and functional hemispherectomies. Acta Neuropathol (1993) 0.87
Mouse chromosome 2. Mamm Genome (1992) 0.84
Anxiety in mice: a principal component analysis study. Neural Plast (2007) 0.83
Canine epilepsy genetics. Mamm Genome (2011) 0.83
Mouse chromosome 9. Mamm Genome (1992) 0.82
The genes encoding the glutamate receptor subunits KA1 and KA2 (GRIK4 and GRIK5) are located on separate chromosomes in human, mouse, and rat. Proc Natl Acad Sci U S A (1994) 0.79
Mouse chromosome 6. Mamm Genome (1992) 0.79
Segregation of seizure traits in C57 black mouse substrains using the repeated-flurothyl model. PLoS One (2014) 0.77
Effect of YM928, a novel AMPA receptor antagonist, on seizures in EL mice and kainate-induced seizures in rats. Naunyn Schmiedebergs Arch Pharmacol (2004) 0.76
Molecular biology of neurological diseases. Postgrad Med J (1992) 0.75
Neuronal mechanism of epileptogenesis in EL mouse. Proc Jpn Acad Ser B Phys Biol Sci (2013) 0.75
The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity. Proc Natl Acad Sci U S A (1998) 9.32
Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy. Nature (2012) 7.76
Structure, replication, and recombination of retrovirus genomes: some unifying hypotheses. J Gen Virol (1979) 7.69
Maps from two interspecific backcross DNA panels available as a community genetic mapping resource. Mamm Genome (1994) 5.38
The nucleotide sequence complexity of avian tumor virus RNA. Proc Natl Acad Sci U S A (1974) 4.86
TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells. J Biol Chem (1997) 4.61
Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy. Proc Natl Acad Sci U S A (2009) 4.58
A physical map of the Rous sarcoma virus genome. J Mol Biol (1976) 4.56
Bacterial beta-galactosidase as a marker of Rous sarcoma virus gene expression and replication. Mol Cell Biol (1985) 4.41
The roads from phenotypic variation to gene discovery: mutagenesis versus QTLs. Nat Genet (2000) 4.28
Who's afraid of epistasis? Nat Genet (1996) 4.24
Highly preferred targets for retrovirus integration. Cell (1988) 3.89
Determinants for receptor interaction and cell killing on the avian retrovirus glycoprotein gp85. Cell (1986) 3.80
Genetic variation in AIDS viruses. Cell (1986) 3.68
The four classes of endogenous murine leukemia virus: structural relationships and potential for recombination. J Virol (1987) 3.57
The mouse stargazer gene encodes a neuronal Ca2+-channel gamma subunit. Nat Genet (1998) 3.31
Proposal for naming host cell-derived inserts in retrovirus genomes. J Virol (1981) 3.18
Absence epilepsy in tottering mutant mice is associated with calcium channel defects. Cell (1996) 3.08
Linkage of Mls genes to endogenous mammary tumour viruses of inbred mice. Nature (1991) 3.07
Comparison of Rous sarcoma virus-specific deoxyribonucleic acid polymerases in virions of Rous sarcoma virus and in Rous sarcoma virus-infected chicken cells. J Virol (1971) 2.97
Recombinants between endogenous and exogenous avian tumor viruses: role of the C region and other portions of the genome in the control of replication and transformation. J Virol (1980) 2.93
At least two regions of the viral genome determine the oncogenic potential of avian leukosis viruses. Proc Natl Acad Sci U S A (1982) 2.84
Structure of the genome of Moloney murine leukemia virus: a terminally redundant sequence. Cell (1978) 2.68
Constructing primate phylogenies from ancient retrovirus sequences. Proc Natl Acad Sci U S A (1999) 2.61
A linkage map of endogenous murine leukemia proviruses. Genetics (1990) 2.60
Disruption of the nuclear hormone receptor RORalpha in staggerer mice. Nature (1996) 2.58
Human immunodeficiency virus type 1 population genetics and adaptation in newly infected individuals. J Virol (2008) 2.56
Sequence interpretation. Functional annotation of mouse genome sequences. Science (2001) 2.54
Short-course raltegravir intensification does not reduce persistent low-level viremia in patients with HIV-1 suppression during receipt of combination antiretroviral therapy. Clin Infect Dis (2010) 2.51
Virological events leading to spontaneous AKR thymomas. J Virol (1991) 2.45
Quantitative determination and location of newly synthesized virus-specific ribonucleic acid in chicken cells infected with Rous sarcoma virus. J Virol (1973) 2.45
Expression of leukemogenic recombinant viruses associated with a recessive gene in HRS/J mice. J Exp Med (1980) 2.38
Mechanism of transduction by retroviruses. Science (1992) 2.37
Role of endogenous retroviruses as mutagens: the hairless mutation of mice. Cell (1988) 2.20
Molecular basis of host range variation in avian retroviruses. J Virol (1985) 2.19
Transition between stochastic evolution and deterministic evolution in the presence of selection: general theory and application to virology. Microbiol Mol Biol Rev (2001) 2.06
Human immunodeficiency virus drug therapy and virus load. J Virol (1997) 2.05
Nucleotide sequence relationships between the genomes of an endogenous and an exogenous avian tumor virus. J Virol (1978) 2.01
Linkage disequilibrium test implies a large effective population number for HIV in vivo. Proc Natl Acad Sci U S A (1999) 2.00
The mouse pudgy mutation disrupts Delta homologue Dll3 and initiation of early somite boundaries. Nat Genet (1998) 1.96
Localization of a retroviral element within the rd gene coding for the beta subunit of cGMP phosphodiesterase. Proc Natl Acad Sci U S A (1993) 1.95
Terminal redundancy and the origin of replication of Rous sarcoma virus RNA. Proc Natl Acad Sci U S A (1977) 1.94
Nonrandom integration of retroviral DNA in vitro: effect of CpG methylation. Proc Natl Acad Sci U S A (1992) 1.94
Relationship of avian retrovirus DNA synthesis to integration in vitro. Mol Cell Biol (1991) 1.92
Hybridization of Rous sarcoma virus deoxyribonucleic acid polymerase product and ribonucleic acids from chicken and rat cells infected with Rous sarcoma virus. J Virol (1972) 1.91
Differential transcription from the long terminal repeats of integrated avian leukosis virus DNA. J Virol (1986) 1.91
A robust measure of HIV-1 population turnover within chronically infected individuals. Mol Biol Evol (2004) 1.87
Structure and expression of the hairless gene of mice. Proc Natl Acad Sci U S A (1994) 1.85
Evidence for genomic rearrangements mediated by human endogenous retroviruses during primate evolution. Nat Genet (2001) 1.81
Polymorphism of murine endogenous proviruses revealed by using virus class-specific oligonucleotide probes. J Virol (1988) 1.80
Distribution of targets for avian retrovirus DNA integration in vivo. Genes Dev (1994) 1.80
Genetic alterations of RNA leukemia viruses associated with the development of spontaneous thymic leukemia in AKR/J mice. J Virol (1982) 1.79
Subgroup-E avian-leukosis-virus-associated disease in chickens. Cold Spring Harb Symp Quant Biol (1980) 1.79
The genome of Uukuniemi virus consists of three unique RNA segments. Cell (1977) 1.78
Ducky mouse phenotype of epilepsy and ataxia is associated with mutations in the Cacna2d2 gene and decreased calcium channel current in cerebellar Purkinje cells. J Neurosci (2001) 1.77
Sodium/hydrogen exchanger gene defect in slow-wave epilepsy mutant mice. Cell (1997) 1.75
Variation in avian retrovirus genomes. Ann N Y Acad Sci (1980) 1.75
Efficient autointegration of avian retrovirus DNA in vitro. J Virol (1990) 1.71
NOR/Lt mice: MHC-matched diabetes-resistant control strain for NOD mice. Diabetes (1992) 1.69
Quantitative trait loci for bone density in C57BL/6J and CAST/EiJ inbred mice. Mamm Genome (1999) 1.68
Role of the C region in relative growth rates of endogenous and exogenous avian oncoviruses. Cold Spring Harb Symp Quant Biol (1980) 1.67
Efficient packaging of readthrough RNA in ALV: implications for oncogene transduction. Science (1987) 1.65
A major effect QTL determined by multiple genes in epileptic EL mice. Genome Res (2000) 1.64
Genetic analysis of endogenous xenotropic murine leukemia viruses: association with two common mouse mutations and the viral restriction locus Fv-1. J Virol (1989) 1.64
Truncated gag-related proteins are produced by large deletion mutants of Rous sarcoma virus and form virus particles. J Virol (1985) 1.63
Mapping host range-specific oligonucleotides within genomes of the ecotropic and mink cell focus-inducing strains of Moloney murine leukemia virus. J Virol (1978) 1.62
Direct isolation of polymorphic markers linked to a trait by genetically directed representational difference analysis. Nat Genet (1994) 1.59
Genetic identification of endogenous polytropic proviruses by using recombinant inbred mice. J Virol (1989) 1.56
Caloric restriction inhibits seizure susceptibility in epileptic EL mice by reducing blood glucose. Epilepsia (2001) 1.54
Ribonuclease-sensitive deoxyribonucleic acid polymerase activity in uninfected rat cells and rat cells infected with Rous sarcoma virus. J Virol (1971) 1.54
Relationship between retroviral DNA integration and gene expression. J Virol (2000) 1.53
In vitro synthesis of Rous sarcoma virus-specific RNA is catalyzed by a DNA-dependent RNA polymerase. Proc Natl Acad Sci U S A (1974) 1.53
Retracted Ceruloplasmin gene defect associated with epilepsy in EL mice. Nat Genet (1994) 1.53
Physical map of the Kirsten sarcoma virus genome as determined by fingerprinting RNase T1-resistant oligonucleotides. J Virol (1978) 1.53
Structures of endogenous nonecotropic murine leukemia virus (MLV) long terminal repeats in wild mice: implication for evolution of MLVs. J Virol (1999) 1.53
Role of methylation in the induced and spontaneous expression of the avian endogenous virus ev-1: DNA structure and gene products. Mol Cell Biol (1982) 1.48
Evolution of human immunodeficiency virus under selection and weak recombination. Genetics (2005) 1.46
The mouse fidgetin gene defines a new role for AAA family proteins in mammalian development. Nat Genet (2000) 1.40
The AXB and BXA set of recombinant inbred mouse strains. Mamm Genome (1992) 1.39
Evolutionary variants of Rous sarcoma virus: large deletion mutants do not result from homologous recombination. J Virol (1985) 1.39
Dietary restriction reduces angiogenesis and growth in an orthotopic mouse brain tumour model. Br J Cancer (2002) 1.38
Mls-1 is encoded by the long terminal repeat open reading frame of the mouse mammary tumor provirus Mtv-7. Proc Natl Acad Sci U S A (1992) 1.37
HIV reservoirs and the possibility of a cure for HIV infection. J Intern Med (2011) 1.37
Genomes of endogenous and exogenous avian retroviruses. Virology (1983) 1.33
A new approach to the isolation of RNA-DNA hybrids and its application to the quantitative determination of labeled tumor virus RNA. J Mol Biol (1974) 1.32
Identification of the mouse neuromuscular degeneration gene and mapping of a second site suppressor allele. Neuron (1998) 1.31
Search for the mechanism of genetic variation in the pro gene of human immunodeficiency virus. J Virol (1999) 1.30
Cloning, mRNA expression, and chromosomal mapping of mouse and human preprocortistatin. Genomics (1997) 1.28
Isotype switching of an immunoglobulin heavy chain transgene occurs by DNA recombination between different chromosomes. Cell (1990) 1.27
The ketogenic diet inhibits epileptogenesis in EL mice: a genetic model for idiopathic epilepsy. Epilepsia (2000) 1.25
Mutant and recombinant avian retroviruses with extended host range. Proc Natl Acad Sci U S A (1980) 1.25
Structure and distribution of endogenous nonecotropic murine leukemia viruses in wild mice. J Virol (1998) 1.23
Role of recombinant ecotropic and polytropic viruses in the development of spontaneous thymic lymphomas in HRS/J mice. J Virol (1984) 1.22
Characterization of Rous sarcoma virus sequences essential for viral gene expression. J Virol (1987) 1.22
A null mutation in inositol polyphosphate 4-phosphatase type I causes selective neuronal loss in weeble mutant mice. Neuron (2001) 1.20
Stimulation-dependent release of adenosine triphosphate from hippocampal slices. Brain Res (1989) 1.20
Chromosome mapping of Rfv3, a host resistance gene to Friend murine retrovirus. J Virol (1995) 1.18