Published in J Virol on January 01, 1980
The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection. Proc Natl Acad Sci U S A (1982) 20.55
On the mechanism of retrovirus-induced avian lymphoid leukosis: deletion and integration of the proviruses. Proc Natl Acad Sci U S A (1981) 3.30
The nucleotide sequence of an untranslated but conserved domain at the 3' end of the avian sarcoma virus genome. Nucleic Acids Res (1980) 3.16
A 3' end fragment encompassing the transcriptional enhancers of nondefective Friend virus confers erythroleukemogenicity on Moloney leukemia virus. J Virol (1984) 3.16
At least two regions of the viral genome determine the oncogenic potential of avian leukosis viruses. Proc Natl Acad Sci U S A (1982) 2.84
Virological events leading to spontaneous AKR thymomas. J Virol (1991) 2.45
Molecular basis of host range variation in avian retroviruses. J Virol (1985) 2.19
Patterns of proviral insertion and deletion in avian leukosis virus-induced lymphomas. J Virol (1986) 1.93
Sequence comparison in the crossover region of an oncogenic avian retrovirus recombinant and its nononcogenic parent: genetic regions that control growth rate and oncogenic potential. Mol Cell Biol (1982) 1.89
cis-acting regulatory elements within gag genes of avian retroviruses. Mol Cell Biol (1987) 1.88
Genetic alterations of RNA leukemia viruses associated with the development of spontaneous thymic leukemia in AKR/J mice. J Virol (1982) 1.79
Noncoding region between the env and src genes of Rous sarcoma virus influences splicing efficiency at the src gene 3' splice site. J Virol (1987) 1.68
Concerted DNA rearrangements in Moloney murine leukemia virus-induced thymomas: a potential synergistic relationship in oncogenesis. J Virol (1985) 1.67
Truncated gag-related proteins are produced by large deletion mutants of Rous sarcoma virus and form virus particles. J Virol (1985) 1.63
Influence of enhancer sequences on thymotropism and leukemogenicity of mink cell focus-forming viruses. J Virol (1989) 1.50
Role of methylation in the induced and spontaneous expression of the avian endogenous virus ev-1: DNA structure and gene products. Mol Cell Biol (1982) 1.48
Long terminal repeat enhancer core sequences in proviruses adjacent to c-myc in T-cell lymphomas induced by a murine retrovirus. J Virol (1995) 1.43
Mutant feline sarcoma proviruses containing the viral oncogene (v-fes) and either feline or murine control elements. J Virol (1983) 1.38
Most sequence differences between the genomes of the Akv virus and a leukemogenic Gross A virus passaged in vitro are located near the 3' terminus. Proc Natl Acad Sci U S A (1980) 1.36
Molecular epidemiology of avian leukosis virus subgroup J in layer flocks in China. J Clin Microbiol (2012) 1.33
Molecular cloning of a highly leukemogenic, ecotropic retrovirus from an AKR mouse. J Virol (1982) 1.27
High spontaneous mutation rate of Rous sarcoma virus demonstrated by direct sequencing of the RNA genome. Nucleic Acids Res (1983) 1.27
Long terminal repeat (LTR) sequences, env, and a region near the 5' LTR influence the pathogenic potential of recombinants between Rous-associated virus types 0 and 1. J Virol (1988) 1.25
Influence of env and long terminal repeat sequences on the tissue tropism of avian leukosis viruses. J Virol (1988) 1.24
Characterization of Rous sarcoma virus sequences essential for viral gene expression. J Virol (1987) 1.22
Cellular DNA region involved in induction of thymic lymphomas (Mlvi-2) maps to mouse chromosome 15. Mol Cell Biol (1984) 1.18
Infection by mink cell focus-forming viruses confers interleukin 2 (IL-2) independence to an IL-2-dependent rat T-cell lymphoma line. Proc Natl Acad Sci U S A (1991) 1.17
The receptor for the subgroup C avian sarcoma and leukosis viruses, Tvc, is related to mammalian butyrophilins, members of the immunoglobulin superfamily. J Virol (2005) 1.17
Rous sarcoma virus contains sequences which permit expression of the gag gene in Escherichia coli. Mol Cell Biol (1983) 1.08
Sequences outside of the long terminal repeat determine the lymphomogenic potential of Rous-associated virus type 1. J Virol (1985) 1.08
Mechanisms of avian retroviral host range extension. J Virol (2003) 1.08
Selection of an avian retrovirus mutant with extended receptor usage. J Virol (1997) 1.05
Identification of key residues in subgroup A avian leukosis virus envelope determining receptor binding affinity and infectivity of cells expressing chicken or quail Tva receptor. J Virol (2001) 1.05
Point mutations in the avian sarcoma/leukosis virus 3' untranslated region result in a packaging defect. J Virol (1999) 1.01
cis-acting elements in the U3 region of a simian immunodeficiency virus. J Virol (1990) 1.01
Genetic mapping of a cellular DNA region involved in induction of thymic lymphomas (Mlvi-1) to mouse chromosome 15. Mol Cell Biol (1985) 1.01
Nucleotide sequence analysis of the long terminal repeat of integrated bovine leukemia provirus DNA and of adjacent viral and host sequences. J Virol (1984) 1.00
Nuclear factor 1 activates the feline leukemia virus long terminal repeat but is posttranscriptionally down-regulated in leukemia cell lines. J Virol (1991) 0.99
The first sequenced carnivore genome shows complex host-endogenous retrovirus relationships. PLoS One (2011) 0.92
Nuclear factors that bind two regions important to transcriptional activity of the simian immunodeficiency virus long terminal repeat. J Virol (1992) 0.92
Evolutionary pressure of a receptor competitor selects different subgroup a avian leukosis virus escape variants with altered receptor interactions. J Virol (2003) 0.91
Comparison of the transcriptional activity of the long terminal repeats of simian immunodeficiency viruses SIVmac251 and SIVmac239 in T-cell lines and macrophage cell lines. J Virol (1991) 0.88
Detection and molecular characterization of J subgroup avian leukosis virus in wild ducks in China. PLoS One (2014) 0.81
Model of the TVA receptor determinants required for efficient infection by subgroup A avian sarcoma and leukosis viruses. J Virol (2014) 0.77
Nucleotide sequence of the long terminal repeat of the avian retrovirus RAV-1: evolution of avian retroviruses. Nucleic Acids Res (1987) 0.77
Replication of endogenous avian retrovirus in permissive and nonpermissive chicken embryo fibroblasts. J Virol (1984) 0.75
Genomic fossils reveal adaptation of non-autonomous pararetroviruses driven by concerted evolution of noncoding regulatory sequences. PLoS Pathog (2017) 0.75
Identification of a transformation-specific antigen induced by an avian sarcoma virus. Nature (1977) 16.32
Mapping unintegrated avian sarcoma virus DNA: termini of linear DNA bear 300 nucleotides present once or twice in two species of circular DNA. Cell (1978) 13.33
DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA. Nature (1976) 9.81
Structure, replication, and recombination of retrovirus genomes: some unifying hypotheses. J Gen Virol (1979) 7.69
Uninfected vertebrate cells contain a protein that is closely related to the product of the avian sarcoma virus transforming gene (src). Proc Natl Acad Sci U S A (1979) 7.55
Continuous tissue culture cell lines derived from chemically induced tumors of Japanese quail. Cell (1977) 7.23
Analysis of unintegrated avian RNA tumor virus double-stranded DNA intermediates. J Virol (1978) 7.06
Characterization of a normal avian cell protein related to the avian sarcoma virus transforming gene product. Cell (1978) 5.95
The nucleotide sequence complexity of avian tumor virus RNA. Proc Natl Acad Sci U S A (1974) 4.86
Recovery of avian sarcoma virus from tumors induced by transformation-defective mutants. J Exp Med (1977) 4.79
A physical map of the Rous sarcoma virus genome. J Mol Biol (1976) 4.56
Nucleotide sequences related to the transforming gene of avian sarcoma virus are present in DNA of uninfected vertebrates. Proc Natl Acad Sci U S A (1978) 4.47
An avian leukosis virus associated with stocks of Rous sarcoma virus. Virology (1962) 4.27
Mapping of biological functions on RNA of avian tumor viruses: location of regions required for transformation and determination of host range. Proc Natl Acad Sci U S A (1975) 4.01
Recombination between viral and cellular sequences generates transforming sarcoma virus. Proc Natl Acad Sci U S A (1978) 3.38
Characteristics of cellular RNA related to the transforming gene of avian sarcoma viruses. Cell (1978) 2.50
Rous sarcoma virus p19 binds to specific double-stranded regions of viral RNA: effect of p19 on cleavage of viral RNA by RNase III. Virology (1978) 2.26
Restriction enzyme analysis of mouse cellular type C viral DNA: emergence of new viral sequences in spontaneous AKR/J lymphomas. Proc Natl Acad Sci U S A (1979) 2.18
Oncogenicity of non-transforming mutants of avian sarcoma viruses. J Gen Virol (1973) 2.14
Uninfected avian cells contain RNA related to the transforming gene of avian sarcoma viruses. Cell (1978) 2.10
Nucleotide sequence relationships between the genomes of an endogenous and an exogenous avian tumor virus. J Virol (1978) 2.01
Intracellular restriction on the growth of induced subgroup E avian type C viruses in chicken cells. J Virol (1976) 1.76
The mechanism for genetic recombination in the avian retroviruses. Curr Top Microbiol Immunol (1978) 1.67
Infection of chick cells by subgroup E viruses. Virology (1976) 1.60
Inheritance and expression of chicken genes that are related to avian leukosis sarcoma virus genes. Curr Top Microbiol Immunol (1978) 1.54
Recombinant avian oncoviruses. II. Alterations in the gag proteins and evidence for intragenic recombination. Virology (1979) 1.53
Organization of shared and unshared sequences in the genomes of chicken endogenous and sarcoma viruses. Cell (1977) 1.36
Oncogenicity of avian leukosis viruses of different subgroups and of mutants of sarcoma viruses. Infect Immun (1977) 1.29
Subgroup-specific antigenic determinants of avian RNA tumor virls structural proteins: analysis of virus recombinants. Virology (1976) 1.07
Recombination between the defective component of an acute leukemia virus and Rous associated virus O, an endogenous virus of chickens. Proc Natl Acad Sci U S A (1979) 1.01
The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase. Cell (1995) 11.86
Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy. Nature (2012) 7.76
Structure, replication, and recombination of retrovirus genomes: some unifying hypotheses. J Gen Virol (1979) 7.69
A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region. Science (1991) 6.54
TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway. Cell (2000) 6.07
The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal. Genes Dev (1997) 5.58
AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas. Proc Natl Acad Sci U S A (1992) 5.24
The nucleotide sequence complexity of avian tumor virus RNA. Proc Natl Acad Sci U S A (1974) 4.86
Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy. Proc Natl Acad Sci U S A (2009) 4.58
A physical map of the Rous sarcoma virus genome. J Mol Biol (1976) 4.56
AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation. Annu Rev Biochem (1999) 4.49
Bacterial beta-galactosidase as a marker of Rous sarcoma virus gene expression and replication. Mol Cell Biol (1985) 4.41
Highly preferred targets for retrovirus integration. Cell (1988) 3.89
Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase. Proc Natl Acad Sci U S A (1997) 3.83
Determinants for receptor interaction and cell killing on the avian retrovirus glycoprotein gp85. Cell (1986) 3.80
Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase. Science (1997) 3.73
Genetic variation in AIDS viruses. Cell (1986) 3.68
The four classes of endogenous murine leukemia virus: structural relationships and potential for recombination. J Virol (1987) 3.57
Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway. EMBO J (1997) 3.34
Cyclin D expression is controlled post-transcriptionally via a phosphatidylinositol 3-kinase/Akt-dependent pathway. J Biol Chem (1998) 3.25
Proposal for naming host cell-derived inserts in retrovirus genomes. J Virol (1981) 3.18
Linkage of Mls genes to endogenous mammary tumour viruses of inbred mice. Nature (1991) 3.07
Comparison of Rous sarcoma virus-specific deoxyribonucleic acid polymerases in virions of Rous sarcoma virus and in Rous sarcoma virus-infected chicken cells. J Virol (1971) 2.97
The Gfi-1 proto-oncoprotein contains a novel transcriptional repressor domain, SNAG, and inhibits G1 arrest induced by interleukin-2 withdrawal. Mol Cell Biol (1996) 2.87
At least two regions of the viral genome determine the oncogenic potential of avian leukosis viruses. Proc Natl Acad Sci U S A (1982) 2.84
A common region for proviral DNA integration in MoMuLV-induced rat thymic lymphomas. Nature (1983) 2.84
AKT1/PKBalpha kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic transformation in NIH3T3 cells. Am J Pathol (2001) 2.81
Structure of the genome of Moloney murine leukemia virus: a terminally redundant sequence. Cell (1978) 2.68
Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation. Mol Cell Biol (1997) 2.67
Gfi-1 encodes a nuclear zinc finger protein that binds DNA and functions as a transcriptional repressor. Mol Cell Biol (1996) 2.64
Constructing primate phylogenies from ancient retrovirus sequences. Proc Natl Acad Sci U S A (1999) 2.61
A linkage map of endogenous murine leukemia proviruses. Genetics (1990) 2.60
Molecular cloning of avian myelocytomatosis virus (MC29) transforming sequences. Proc Natl Acad Sci U S A (1981) 2.59
Human immunodeficiency virus type 1 population genetics and adaptation in newly infected individuals. J Virol (2008) 2.56
Short-course raltegravir intensification does not reduce persistent low-level viremia in patients with HIV-1 suppression during receipt of combination antiretroviral therapy. Clin Infect Dis (2010) 2.51
Virological events leading to spontaneous AKR thymomas. J Virol (1991) 2.45
Quantitative determination and location of newly synthesized virus-specific ribonucleic acid in chicken cells infected with Rous sarcoma virus. J Virol (1973) 2.45
Expression of leukemogenic recombinant viruses associated with a recessive gene in HRS/J mice. J Exp Med (1980) 2.38
Progression of interleukin-2 (IL-2)-dependent rat T cell lymphoma lines to IL-2-independent growth following activation of a gene (Gfi-1) encoding a novel zinc finger protein. Mol Cell Biol (1993) 2.37
Mechanism of transduction by retroviruses. Science (1992) 2.37
Role of endogenous retroviruses as mutagens: the hairless mutation of mice. Cell (1988) 2.20
Molecular basis of host range variation in avian retroviruses. J Virol (1985) 2.19
Transition between stochastic evolution and deterministic evolution in the presence of selection: general theory and application to virology. Microbiol Mol Biol Rev (2001) 2.06
The proteins encoded by c-akt and v-akt differ in post-translational modification, subcellular localization and oncogenic potential. Oncogene (1993) 2.05
Human immunodeficiency virus drug therapy and virus load. J Virol (1997) 2.05
AH/PH domain-mediated interaction between Akt molecules and its potential role in Akt regulation. Mol Cell Biol (1995) 2.03
Nucleotide sequence relationships between the genomes of an endogenous and an exogenous avian tumor virus. J Virol (1978) 2.01
Tpl-2 acts in concert with Ras and Raf-1 to activate mitogen-activated protein kinase. Proc Natl Acad Sci U S A (1994) 2.00
Linkage disequilibrium test implies a large effective population number for HIV in vivo. Proc Natl Acad Sci U S A (1999) 2.00
Akt is a direct target of the phosphatidylinositol 3-kinase. Activation by growth factors, v-src and v-Ha-ras, in Sf9 and mammalian cells. J Biol Chem (1996) 1.97
Localization of a retroviral element within the rd gene coding for the beta subunit of cGMP phosphodiesterase. Proc Natl Acad Sci U S A (1993) 1.95
Tumor progression locus 2 (Tpl-2) encodes a protein kinase involved in the progression of rodent T-cell lymphomas and in T-cell activation. Proc Natl Acad Sci U S A (1993) 1.95
Terminal redundancy and the origin of replication of Rous sarcoma virus RNA. Proc Natl Acad Sci U S A (1977) 1.94
Nonrandom integration of retroviral DNA in vitro: effect of CpG methylation. Proc Natl Acad Sci U S A (1992) 1.94
Relationship of avian retrovirus DNA synthesis to integration in vitro. Mol Cell Biol (1991) 1.92
Hybridization of Rous sarcoma virus deoxyribonucleic acid polymerase product and ribonucleic acids from chicken and rat cells infected with Rous sarcoma virus. J Virol (1972) 1.91
Differential transcription from the long terminal repeats of integrated avian leukosis virus DNA. J Virol (1986) 1.91
Sequence comparison in the crossover region of an oncogenic avian retrovirus recombinant and its nononcogenic parent: genetic regions that control growth rate and oncogenic potential. Mol Cell Biol (1982) 1.89
A robust measure of HIV-1 population turnover within chronically infected individuals. Mol Biol Evol (2004) 1.87
Structure and expression of the hairless gene of mice. Proc Natl Acad Sci U S A (1994) 1.85
p50(cdc37) acting in concert with Hsp90 is required for Raf-1 function. Mol Cell Biol (1999) 1.83
Evidence for genomic rearrangements mediated by human endogenous retroviruses during primate evolution. Nat Genet (2001) 1.81
Polymorphism of murine endogenous proviruses revealed by using virus class-specific oligonucleotide probes. J Virol (1988) 1.80
Distribution of targets for avian retrovirus DNA integration in vivo. Genes Dev (1994) 1.80
Genetic alterations of RNA leukemia viruses associated with the development of spontaneous thymic leukemia in AKR/J mice. J Virol (1982) 1.79
Subgroup-E avian-leukosis-virus-associated disease in chickens. Cold Spring Harb Symp Quant Biol (1980) 1.79
The genome of Uukuniemi virus consists of three unique RNA segments. Cell (1977) 1.78
Tpl-2 induces IL-2 expression in T-cell lines by triggering multiple signaling pathways that activate NFAT and NF-kappaB. Oncogene (1998) 1.77
Insertion of an Alu SINE in the human homologue of the Mlvi-2 locus. Nucleic Acids Res (1985) 1.76
Variation in avian retrovirus genomes. Ann N Y Acad Sci (1980) 1.75
Efficient autointegration of avian retrovirus DNA in vitro. J Virol (1990) 1.71
Oncogenic transformation induced by membrane-targeted Akt2 and Akt3. Oncogene (2001) 1.70
Concerted DNA rearrangements in Moloney murine leukemia virus-induced thymomas: a potential synergistic relationship in oncogenesis. J Virol (1985) 1.67
Role of the C region in relative growth rates of endogenous and exogenous avian oncoviruses. Cold Spring Harb Symp Quant Biol (1980) 1.67
Efficient packaging of readthrough RNA in ALV: implications for oncogene transduction. Science (1987) 1.65
Genetic analysis of endogenous xenotropic murine leukemia viruses: association with two common mouse mutations and the viral restriction locus Fv-1. J Virol (1989) 1.64
Truncated gag-related proteins are produced by large deletion mutants of Rous sarcoma virus and form virus particles. J Virol (1985) 1.63
Long-distance activation of the Myc protooncogene by provirus insertion in Mlvi-1 or Mlvi-4 in rat T-cell lymphomas. Proc Natl Acad Sci U S A (1990) 1.63
Mapping host range-specific oligonucleotides within genomes of the ecotropic and mink cell focus-inducing strains of Moloney murine leukemia virus. J Virol (1978) 1.62
Tpl-2 is an oncogenic kinase that is activated by carboxy-terminal truncation. Genes Dev (1997) 1.57
The Gfi-1B proto-oncoprotein represses p21WAF1 and inhibits myeloid cell differentiation. Mol Cell Biol (1998) 1.57
Genetic identification of endogenous polytropic proviruses by using recombinant inbred mice. J Virol (1989) 1.56
Ribonuclease-sensitive deoxyribonucleic acid polymerase activity in uninfected rat cells and rat cells infected with Rous sarcoma virus. J Virol (1971) 1.54
Relationship between retroviral DNA integration and gene expression. J Virol (2000) 1.53
Physical map of the Kirsten sarcoma virus genome as determined by fingerprinting RNase T1-resistant oligonucleotides. J Virol (1978) 1.53
In vitro synthesis of Rous sarcoma virus-specific RNA is catalyzed by a DNA-dependent RNA polymerase. Proc Natl Acad Sci U S A (1974) 1.53
Structures of endogenous nonecotropic murine leukemia virus (MLV) long terminal repeats in wild mice: implication for evolution of MLVs. J Virol (1999) 1.53
PDK2: a complex tail in one Akt. Sci STKE (2001) 1.50
Structure, expression and chromosomal mapping of c-akt: relationship to v-akt and its implications. Oncogene (1993) 1.49
Role of methylation in the induced and spontaneous expression of the avian endogenous virus ev-1: DNA structure and gene products. Mol Cell Biol (1982) 1.48
Tumor induction by an Lck-MyrAkt transgene is delayed by mechanisms controlling the size of the thymus. Proc Natl Acad Sci U S A (2001) 1.47
Evolution of human immunodeficiency virus under selection and weak recombination. Genetics (2005) 1.46
A novel plant glutathione S-transferase/peroxidase suppresses Bax lethality in yeast. J Biol Chem (2000) 1.44
Akt, a target of phosphatidylinositol 3-kinase, inhibits apoptosis in a differentiating neuronal cell line. Mol Cell Biol (1998) 1.41
Evolutionary variants of Rous sarcoma virus: large deletion mutants do not result from homologous recombination. J Virol (1985) 1.39