Hiromitsu Hara

Author PubWeight™ 44.36‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Mincle is an ITAM-coupled activating receptor that senses damaged cells. Nat Immunol 2008 4.66
2 Resident Vdelta1+ gammadelta T cells control early infiltration of neutrophils after Escherichia coli infection via IL-17 production. J Immunol 2007 4.11
3 Identifying the MAGUK protein Carma-1 as a central regulator of humoral immune responses and atopy by genome-wide mouse mutagenesis. Immunity 2003 3.36
4 Essential role of IL-17A in the formation of a mycobacterial infection-induced granuloma in the lung. J Immunol 2010 2.70
5 Impaired heart contractility in Apelin gene-deficient mice associated with aging and pressure overload. Circ Res 2007 1.74
6 Probiotic Bifidobacterium breve induces IL-10-producing Tr1 cells in the colon. PLoS Pathog 2012 1.68
7 Cutting edge: TLR2 directly triggers Th1 effector functions. J Immunol 2007 1.61
8 The E3 ligase HACE1 is a critical chromosome 6q21 tumor suppressor involved in multiple cancers. Nat Med 2007 1.55
9 Phosphorylation and ubiquitination of the IkappaB kinase complex by two distinct signaling pathways. EMBO J 2007 1.54
10 The molecular scaffold Gab2 is a crucial component of RANK signaling and osteoclastogenesis. Nat Med 2005 1.39
11 CXCL10-CXCR3 enhances the development of neutrophil-mediated fulminant lung injury of viral and nonviral origin. Am J Respir Crit Care Med 2012 1.28
12 A critical role for the innate immune signaling molecule IRAK-4 in T cell activation. Science 2006 1.16
13 Notch-Hes1 pathway is required for the development of IL-17-producing γδ T cells. Blood 2011 1.14
14 Importance of murine Vdelta1gammadelta T cells expressing interferon-gamma and interleukin-17A in innate protection against Listeria monocytogenes infection. Immunology 2008 1.04
15 Vdelta1+ gammadelta T cells producing CC chemokines may bridge a gap between neutrophils and macrophages in innate immunity during Escherichia coli infection in mice. J Immunol 2004 1.01
16 IL-1 receptor-associated kinase 4 is essential for IL-18-mediated NK and Th1 cell responses. J Immunol 2003 1.00
17 Tumor-specific cytotoxic T cell generation and dendritic cell function are differentially regulated by interleukin 27 during development of anti-tumor immunity. Int J Cancer 2009 0.99
18 IL-1R-associated kinase 4 is required for lipopolysaccharide-induced activation of APC. J Immunol 2003 0.99
19 Protective role of naturally occurring interleukin-17A-producing γδ T cells in the lung at the early stage of systemic candidiasis in mice. Infect Immun 2011 0.95
20 IL-23-dependent and -independent enhancement pathways of IL-17A production by lactic acid. Int Immunol 2010 0.94
21 Exacerbation of delayed-type hypersensitivity responses in EBV-induced gene-3 (EBI-3)-deficient mice. Immunol Lett 2010 0.91
22 Targeted deletion of both thymidine phosphorylase and uridine phosphorylase and consequent disorders in mice. Mol Cell Biol 2002 0.91
23 Defect of CARD9 leads to impaired accumulation of gamma interferon-producing memory phenotype T cells in lungs and increased susceptibility to pulmonary infection with Cryptococcus neoformans. Infect Immun 2014 0.90
24 Propionibacterium acnes-induced IL-8 production may be mediated by NF-kappaB activation in human monocytes. J Dermatol Sci 2002 0.89
25 Syk-dependent signaling pathways in neutrophils and macrophages are indispensable in the pathogenesis of anti-collagen antibody-induced arthritis. Int Immunol 2012 0.88
26 Coronin 1A is an essential regulator of the TGFβ receptor/SMAD3 signaling pathway in Th17 CD4(+) T cells. J Autoimmun 2011 0.88
27 IL-27 inhibits hyperglycemia and pancreatic islet inflammation induced by streptozotocin in mice. Am J Pathol 2011 0.81
28 Interleukin 27 inhibits atherosclerosis via immunoregulation of macrophages in mice. Am J Physiol Heart Circ Physiol 2013 0.81
29 Alternative cell death of Apaf1-deficient neural progenitor cells induced by withdrawal of EGF or insulin. Biochim Biophys Acta 2009 0.81
30 Vdelta1+ T cells are crucial for repertoire formation of gammadelta T cells in the lung. Biochem Biophys Res Commun 2007 0.78
31 Germ-line elimination of electric charge on pre-T-cell receptor (TCR) impairs autonomous signaling for beta-selection and TCR repertoire formation. Proc Natl Acad Sci U S A 2010 0.77
32 A C-type lectin receptor pathway is responsible for the pathogenesis of acute cyclophosphamide-induced cystitis in mice. Microbiol Immunol 2013 0.76
33 Amelioration of experimental allergic rhinitis with suppression of topical immune responses by lack of IL-27/WSX-1 signaling. Ann Allergy Asthma Immunol 2009 0.75
34 Identification of 62-kDa protein as an immunogenic antigen of Vibrio vulnificus for humans. Fukuoka Igaku Zasshi 2013 0.75