Published in Biochim Biophys Acta on January 18, 1978
Nesidioblastosis of the pancreas: definition of the syndrome and the management of the severe neonatal hyperinsulinaemic hypoglycaemia. Arch Dis Child (1981) 2.36
Glucose homeostasis across human airway epithelial cell monolayers: role of diffusion, transport and metabolism. Pflugers Arch (2008) 1.12
Sodium/hydrogen exchanger NHA2 is critical for insulin secretion in β-cells. Proc Natl Acad Sci U S A (2013) 0.85
Glucose induces closure of single potassium channels in isolated rat pancreatic beta-cells. Nature (1985) 5.52
The pentose cycle and insulin release in mouse pancreatic islets. Biochem J (1972) 2.79
Glucose metabolism in mouse pancreatic islets. Biochem J (1970) 2.54
Interrelationship of islet metabolism, adenosine triphosphate content and insulin release. Biochem J (1973) 2.48
AMP-activated protein kinase is activated by low glucose in cell lines derived from pancreatic beta cells, and may regulate insulin release. Biochem J (1998) 2.45
Nesidioblastosis of the pancreas: definition of the syndrome and the management of the severe neonatal hyperinsulinaemic hypoglycaemia. Arch Dis Child (1981) 2.36
The ATP-sensitivity of K+ channels in rat pancreatic B-cells is modulated by ADP. FEBS Lett (1986) 2.09
Glucoreceptor mechanisms and the control of insulin release and biosynthesis. Diabetologia (1980) 1.90
Enzymes of glucose metabolism in normal mouse pancreatic islets. Biochem J (1970) 1.73
Properties of single potassium channels modulated by glucose in rat pancreatic beta-cells. J Physiol (1988) 1.63
Promiscuous coupling between the sulphonylurea receptor and inwardly rectifying potassium channels. Nature (1996) 1.57
Identification of the high-affinity tolbutamide site on the SUR1 subunit of the K(ATP) channel. Diabetes (1999) 1.44
Presence and possible role of calcium-dependent regulator (calmodulin) in rat islets of Langerhans. FEBS Lett (1979) 1.34
Effects of Ca2+, calmodulin and cyclic AMP on the phosphorylation of endogenous proteins by homogenates of rt islets of langerhans. Biochim Biophys Acta (1982) 1.30
Glucose-6-phosphatase activity of mouse pancreatic islets. Nature (1968) 1.24
Control of insulin gene expression by glucose. Biochem J (1992) 1.23
Association studies of variants in promoter and coding regions of beta-cell ATP-sensitive K-channel genes SUR1 and Kir6.2 with Type 2 diabetes mellitus (UKPDS 53). Diabet Med (2001) 1.19
The effects of glucose, N-acetylglucosamine, glyceraldehyde and other sugars on insulin release in vivo. Diabetologia (1975) 1.17
Glucose regulates preproinsulin messenger RNA levels in a clonal cell line of simian virus 40-transformed B cells. FEBS Lett (1987) 1.17
Identification and characterization of Ca2+-phospholipid-dependent protein kinase in rat islets and hamster beta-cells. Biochem J (1984) 1.16
Concentration of adenosine 3':5'-cyclic monophosphate in mouse pancreatic islets measured by a protein-binding radioassay. Biochem J (1973) 1.15
The effect of sugars on (pro)insulin biosynthesis. Biochem J (1978) 1.15
The dependence on intracellular ATP concentration of ATP-sensitive K-channels and of Na,K-ATPase in intact HIT-T15 beta-cells. FEBS Lett (1989) 1.14
Insulin secretory responses of a clonal cell line of simian virus 40-transformed B cells. Diabetologia (1986) 1.13
Molecular structure of the glibenclamide binding site of the beta-cell K(ATP) channel. FEBS Lett (2001) 1.10
Identification of functional ionotropic glutamate receptor proteins in pancreatic beta-cells and in islets of Langerhans. FEBS Lett (1995) 1.09
Protein phosphorylation in the pancreatic B-cell. Experientia (1984) 1.09
Evidence for the participation of calmodulin in stimulus-secretion coupling in the pancreatic beta-cell. Biochem J (1980) 1.08
Isoforms of endoplasmic reticulum Ca(2+)-ATPase are differentially expressed in normal and diabetic islets of Langerhans. Biochem J (1996) 1.08
Cloning of the promoters for the beta-cell ATP-sensitive K-channel subunits Kir6.2 and SUR1. Diabetes (1998) 1.08
Sulfonylureas enhance exocytosis from pancreatic beta-cells by a mechanism that does not involve direct activation of protein kinase C. Diabetes (1998) 1.07
Studies on the role of calcium ions in the stimulation by adrenaline of amylase release from rat parotid. Biochem J (1974) 1.06
Pharmacological characterisation of the antihyperglycaemic properties of Tinospora crispa extract. J Ethnopharmacol (1998) 1.05
Regulation and specificity of glucose-stimulated insulin gene expression in human islets of Langerhans. FEBS Lett (1987) 1.04
ATP-sensitive K-channels in HIT T15 beta-cells studied by patch-clamp methods, 86Rb efflux and glibenclamide binding. Pflugers Arch (1989) 1.03
Cyclic AMP-dependent protein phosphorylation and insulin secretion in intact islets of Langerhans. Biochem J (1984) 1.03
Effects of phosphoenolpyruvate, other glycolytic intermediates and methylxanthines on calcium uptake by a mitochondrial fraction from rat pancreatic islets. Diabetologia (1978) 1.03
Time course studies of glucose-induced changes in glucose-6-phosphate and fructose-1,6-diphosphate content of mouse and rat pancreatic islets. Diabetologia (1973) 1.03
Effects of 2-ketoisocaproate on insulin release and single potassium channel activity in dispersed rat pancreatic beta-cells. J Physiol (1987) 1.02
The control of insulin release by sugars. Ciba Found Symp (1976) 1.01
The effect of nickel on secretory systems. Studies on the release of amylase, insulin and growth hormone. Biochem J (1974) 1.01
Effects of glucose on the cytosolic ration of reduced/oxidized nicotinamide-adenine dinucleotide phosphate in rat islets of Langerhans. Biochem J (1979) 1.00
Insulin secretion mechanisms and glucose metabolism in isolated islets. Diabetes (1972) 1.00
Antidiabetic effects of Tinospora crispa in rats. J Ethnopharmacol (1989) 0.99
Potentiators of insulin secretion modulate Ca2+ sensitivity in rat pancreatic islets. Mol Cell Endocrinol (1987) 0.98
Protein kinase activities in rat pancreatic islets of Langerhans. Biochem J (1979) 0.96
Expression of functionally active ATP-sensitive K-channels in insect cells using baculovirus. FEBS Lett (1998) 0.95
Substrates for cyclic AMP-dependent protein kinase in islets of Langerhans. Studies with forskolin and catalytic subunit. Biochem J (1985) 0.95
Glucose phosphorylation in mouse pancreatic islets. Biochem J (1968) 0.95
A truncated isoform of Ca2+/calmodulin-dependent protein kinase II expressed in human islets of Langerhans may result from trans-splicing. FEBS Lett (1997) 0.95
Insulin release from human pancreatic islets in vitro. Diabetologia (1980) 0.94
The hypoglycaemic and insulinotropic activity of Tinospora crispa: studies with human and rat islets and HIT-T15 B cells. Diabetologia (1989) 0.94
Phosphoenolpyruvate in rat pancreatic islets: a possible intracellular trigger of insulin release? Diabetologia (1977) 0.92
Isolation of human pancreatic islets capable of releasing insulin and metabolising glucose in vitro. Lancet (1971) 0.92
The effect of N-acylglucosamines on the biosynthesis and secretion of insulin in the rat. Biochem J (1976) 0.92
Diabetogenic action of alloxan-like compounds: the effect of dehydrouramil hydrate hydrochloride on isolated islets of Langerhans of the rat. Diabetologia (1983) 0.91
Cyclic nucleotide phosphodiesterase of rat pancreatic islets. Effects of Ca2+, calmodulin and trifluoperazine. Biochem J (1981) 0.91
Effects of a phorbol ester and clomiphene on protein phosphorylation and insulin secretion in rat pancreatic islets. Biochem J (1988) 0.90
Diabetogenic action of alloxan-like compounds: cytotoxic effects of 5-hydroxy-pseudouric acid and dehydrouramil hydrate hydrochloride on rat pancreatic beta cells. Diabetologia (1984) 0.89
Glucose modulation of ATP-sensitive K-currents in wild-type, homozygous and heterozygous glucokinase knock-out mice. Diabetologia (1998) 0.88
The glucose sensor in HIT cells is the glucose transporter. FEBS Lett (1987) 0.87
Interactions of the sulfonylurea receptor 1 subunit in the molecular assembly of beta-cell K(ATP) channels. J Biol Chem (2000) 0.87
Effect of adrenal steroids on insulin release from cultured rat islets of Langerhans. Diabetologia (1986) 0.87
Sequence variants of the sarco(endo)plasmic reticulum Ca(2+)-transport ATPase 3 gene (SERCA3) in Caucasian type II diabetic patients (UK Prospective Diabetes Study 48). Diabetologia (1999) 0.87
Expression of voltage-gated K+ channels in insulin-producing cells. Analysis by polymerase chain reaction. FEBS Lett (1990) 0.85
A unique combination of plasma membrane Ca2+-ATPase isoforms is expressed in islets of Langerhans and pancreatic beta-cell lines. Biochem J (1996) 0.85
Characteristics of the adenohypophyseal Ca2+-phospholipid-dependent protein kinase. Mol Cell Endocrinol (1984) 0.85
A novel pancreatic beta-cell isoform of calcium/calmodulin-dependent protein kinase II (beta 3 isoform) contains a proline-rich tandem repeat in the association domain. FEBS Lett (1995) 0.85
Calcitonin gene-related peptide and somatostatin inhibit insulin release from individual rat B cells. Mol Cell Endocrinol (1988) 0.84
Effect of secretagogues on cytosolic free Ca2+ and insulin release in the hamster clonal beta-cell line HIT-T15. J Mol Endocrinol (1988) 0.84
Investigation of the molecular assembly of beta-cell K(ATP) channels. FEBS Lett (2000) 0.83
Effect of secretagogues on cytosolic free Ca2+ and insulin release at different extracellular Ca2+ concentrations in the hamster clonal beta-cell line HIT-T15. Mol Cell Endocrinol (1989) 0.83
The role of cytosolic free Ca2+ and protein kinase C in acetylcholine-induced insulin release in the clonal beta-cell line, HIT-T15. Biochem J (1990) 0.83
Superoxide dismutase activity in lymphocytes and polymorphonuclear cells of diabetic patients. Eur J Clin Chem Clin Biochem (1997) 0.83
Effects of cholinergic agonists on diacylglycerol and intracellular calcium levels in pancreatic beta-cells. Cell Signal (1993) 0.82
The beta-cell glibenclamide receptor is an ADP-binding protein. Biochem J (1990) 0.82
Possible involvement of protein phosphorylation in the regulation of the sulphonylurea receptor of a pancreatic beta-cell line, HIT T15. Biochim Biophys Acta (1991) 0.82
Protein kinase C in beta-cells: expression of multiple isoforms and involvement in cholinergic stimulation of insulin secretion. Mol Cell Endocrinol (1996) 0.81
Structure-activity relationships of alloxan-like compounds derived from uric acid. Br J Pharmacol (1986) 0.80
Effects of dehydrouramil on protein phosphorylation and insulin secretion in rat islets of Langerhans. Biochem J (1986) 0.80
N-acetylglucosamine and the substrate-site hypothesis for the control of insulin biosynthesis and secretion. FEBS Lett (1978) 0.80
Differential expression of the inwardly-rectifying K-channel ROMK1 in rat brain. Brain Res Mol Brain Res (1994) 0.79
[Metabolism and insulin secretion in isolated islets]. Acta Diabetol Lat (1969) 0.79
Detection of islet cell surface antibodies using cloned beta cells and comparison of their incidence with that of islet cell cytoplasmic antibodies. Diabetes Res (1985) 0.79
Protein carboxymethylation in rat islets of Langerhans. FEBS Lett (1982) 0.79
Characterisation of endoplasmic reticulum and plasma membrane Ca(2+)-ATPases in pancreatic beta-cells and in islets of Langerhans. Biochim Biophys Acta (1995) 0.79
Characterization of Ca2+/calmodulin-dependent protein kinase in rat pancreatic islets. Biochem J (1993) 0.79
A potassium channel modulated by glucose metabolism in rat pancreatic beta-cells. Adv Exp Med Biol (1986) 0.78
Human islets of Langerhans express multiple isoforms of calcium/calmodulin-dependent protein kinase II. Biochem Biophys Res Commun (1997) 0.78
Stimulation of insulin release by vasopressin in the clonal beta-cell line, HIT-T15: the role of protein kinase C. J Mol Endocrinol (1992) 0.78
Carbohydrate metabolism in pancreatic islets and the release of insulin. Biochem J (1969) 0.78
Carbohydrate metabolism and the glucoreceptor mechanism. Horm Metab Res Suppl (1980) 0.77
[Bioenergetics of islet function: islet glucose metabolism]. Acta Diabetol Lat (1970) 0.77
Mechanisms in the control of insulin release by glucose and other substances. Adv Metab Disord (1970) 0.77
Control of insulin release by glucose. Proc R Soc Med (1968) 0.76
Trans-acting factor(s) confer glucose-responsive transcriptional regulation in the insulin gene. Adv Exp Med Biol (1997) 0.76
Plasma uric acid and total antioxidant status in patients with diabetes mellitus. Horm Metab Res (1997) 0.76
Structure-function relationships in the beta-cell K(ATP) channel. Biochem Soc Trans (2002) 0.76
Human islets of Langerhans express the delta(C) isoform of calcium/calmodulin-dependent protein kinase II. Diabetes Metab Res Rev (1999) 0.76
Beta-cell recognition of stereoisomers of D-glucose. Diabetologia (1979) 0.75