Published in J Pharmacol Exp Ther on September 12, 2008
Structure and function of the human breast cancer resistance protein (BCRP/ABCG2). Curr Drug Metab (2010) 1.33
Development and function of the human fetal adrenal cortex: a key component in the feto-placental unit. Endocr Rev (2010) 1.14
Melanoma spheroids grown under neural crest cell conditions are highly plastic migratory/invasive tumor cells endowed with immunomodulator function. PLoS One (2011) 1.07
Abcg2 labels multiple cell types in skeletal muscle and participates in muscle regeneration. J Cell Biol (2011) 1.02
ATP-binding cassette efflux transporters in human placenta. Curr Pharm Biotechnol (2011) 0.98
Changes in the expression of miR-381 and miR-495 are inversely associated with the expression of the MDR1 gene and development of multi-drug resistance. PLoS One (2013) 0.97
A comprehensive study of polymorphisms in the ABCB1, ABCC2, ABCG2, NR1I2 genes and lymphoma risk. Int J Cancer (2011) 0.95
ABCG2 null alleles define the Jr(a-) blood group phenotype. Nat Genet (2012) 0.94
Cardiac-derived stem cell-based therapy for heart failure: progress and clinical applications. Exp Biol Med (Maywood) (2013) 0.94
Role of P-glycoprotein in the distribution of the HIV protease inhibitor atazanavir in the brain and male genital tract. Antimicrob Agents Chemother (2013) 0.91
Biological characteristics of Rh123(high) stem-like cells in a side population of 786-O renal carcinoma cells. Oncol Lett (2013) 0.89
Prostate cancer stem cells. Cent European J Urol (2011) 0.84
Celecoxib treatment restores pharmacosensitivity in a rat model of pharmacoresistant epilepsy. Br J Pharmacol (2010) 0.83
Regulatory pathways for ATP-binding cassette transport proteins in kidney proximal tubules. AAPS J (2012) 0.83
Proliferation of dental follicle-derived cell populations in heat-stress conditions. Cell Prolif (2011) 0.82
Corpora amylacea deposition in the hippocampus of patients with mesial temporal lobe epilepsy: A new role for an old gene? Indian J Hum Genet (2011) 0.82
Gene expression profiling of transporters in the solute carrier and ATP-binding cassette superfamilies in human eye substructures. Mol Pharm (2013) 0.80
ATP-binding cassette G-subfamily transporter 2 regulates cell cycle progression and asymmetric division in mouse cardiac side population progenitor cells. Circ Res (2012) 0.80
The role of Brugia malayi ATP-binding cassette (ABC) transporters in potentiating drug sensitivity. Parasitol Res (2011) 0.79
Integrative analyses of hepatic differentially expressed genes and blood biomarkers during the peripartal period between dairy cows overfed or restricted-fed energy prepartum. PLoS One (2014) 0.79
ABCG2 is a selectable marker for enhanced multilineage differentiation potential in periodontal ligament stem cells. Stem Cells Dev (2015) 0.78
The effects of ABCG2 on the viability, proliferation and paracrine actions of kidney side population cells under oxygen-glucose deprivation. Int J Med Sci (2014) 0.77
Functional coupling of ATP-binding cassette transporter Abcb6 to cytochrome P450 expression and activity in liver. J Biol Chem (2015) 0.76
Multidrug-resistance proteins are weak tumor associated antigens for colorectal carcinoma. BMC Immunol (2011) 0.76
Cannabidiol changes P-gp and BCRP expression in trophoblast cell lines. PeerJ (2013) 0.76
ABCG2 is a potential prognostic marker of overall survival in patients with clear cell renal cell carcinoma. BMC Cancer (2017) 0.75
Expression of P-gp in acute myeloid leukemia and the reversal function of As2O3 on drug resistance. Oncol Lett (2014) 0.75
Genome-wide association study of cardiotoxicity in the NCCTG N9831 (Alliance) adjuvant trastuzumab trial. Pharmacogenet Genomics (2017) 0.75
The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: putative efflux pump for urinary cAMP and cGMP. J Am Soc Nephrol (2002) 1.94
Alkaline phosphatase treatment improves renal function in severe sepsis or septic shock patients. Crit Care Med (2009) 1.93
Multidrug resistance protein 4 (MRP4/ABCC4): a versatile efflux transporter for drugs and signalling molecules. Trends Pharmacol Sci (2008) 1.88
Intravenously administered short interfering RNA accumulates in the kidney and selectively suppresses gene function in renal proximal tubules. Drug Metab Dispos (2006) 1.71
Ischemic preconditioning in the animal kidney, a systematic review and meta-analysis. PLoS One (2012) 1.56
Renal toxicity of radiolabeled peptides and antibody fragments: mechanisms, impact on radionuclide therapy, and strategies for prevention. J Nucl Med (2010) 1.46
Potential role for adenosine in the pathogenesis of the vascular complications of hyperhomocysteinemia. Cardiovasc Res (2003) 1.42
Interaction of nonsteroidal anti-inflammatory drugs with multidrug resistance protein (MRP) 2/ABCC2- and MRP4/ABCC4-mediated methotrexate transport. J Pharmacol Exp Ther (2006) 1.41
Gelatin-based plasma expander effectively reduces renal uptake of 111In-octreotide in mice and rats. J Nucl Med (2006) 1.37
Human organic anion transporter MRP4 (ABCC4) is an efflux pump for the purine end metabolite urate with multiple allosteric substrate binding sites. Am J Physiol Renal Physiol (2004) 1.34
Renal uptake of radiolabeled octreotide in human subjects is efficiently inhibited by succinylated gelatin. J Nucl Med (2006) 1.34
Upregulation of renal inducible nitric oxide synthase during human endotoxemia and sepsis is associated with proximal tubule injury. Clin J Am Soc Nephrol (2006) 1.17
Multidrug resistance protein 4 (MRP4/ABCC4) regulates cAMP cellular levels and controls human leukemia cell proliferation and differentiation. J Biol Chem (2011) 1.15
Molecular aspects of renal anionic drug transport. Annu Rev Physiol (2002) 1.14
Selective iNOS inhibition for the treatment of sepsis-induced acute kidney injury. Nat Rev Nephrol (2009) 1.14
Novel conditionally immortalized human proximal tubule cell line expressing functional influx and efflux transporters. Cell Tissue Res (2009) 1.14
Remote ischaemic preconditioning by brief hind limb ischaemia protects against renal ischaemia-reperfusion injury: the role of adenosine. Nephrol Dial Transplant (2011) 1.14
Reducing renal uptake of radiolabeled peptides using albumin fragments. J Nucl Med (2008) 1.05
Prophylactic effect of recombinant factor VIIa in factor VII deficient patients. Br J Haematol (2004) 1.05
The kinetic and biological activity of different loaded rhBMP-2 calcium phosphate cement implants in rats. J Biomed Mater Res A (2008) 1.04
Cysteamine restores glutathione redox status in cultured cystinotic proximal tubular epithelial cells. Biochim Biophys Acta (2011) 1.04
Biomarker discovery with SELDI-TOF MS in human urine associated with early renal injury: evaluation with computational analytical tools. Nephrol Dial Transplant (2007) 1.02
Usage patterns of personal care products: important factors for exposure assessment. Food Chem Toxicol (2012) 1.02
Contribution of multidrug resistance protein 2 (MRP2/ABCC2) to the renal excretion of p-aminohippurate (PAH) and identification of MRP4 (ABCC4) as a novel PAH transporter. J Am Soc Nephrol (2004) 1.02
The ABCs of multidrug resistance in malaria. Trends Parasitol (2010) 1.01
Mass spectrometry analysis of hepcidin peptides in experimental mouse models. PLoS One (2011) 1.00
Uremic toxins inhibit transport by breast cancer resistance protein and multidrug resistance protein 4 at clinically relevant concentrations. PLoS One (2011) 0.99
Cysteamine: an old drug with new potential. Drug Discov Today (2013) 0.97
Mechanisms of renal anionic drug transport. Eur J Pharmacol (2008) 0.96
Hyperuricemia influences tryptophan metabolism via inhibition of multidrug resistance protein 4 (MRP4) and breast cancer resistance protein (BCRP). Biochim Biophys Acta (2013) 0.95
Involvement of VDAC, Bax and ceramides in the efflux of AIF from mitochondria during curcumin-induced apoptosis. PLoS One (2009) 0.94
Impaired renal secretion of substrates for the multidrug resistance protein 2 in mutant transport-deficient (TR-) rats. J Am Soc Nephrol (2003) 0.92
HMOX1 promoter polymorphism modulates the relationship between disease activity and joint damage in rheumatoid arthritis. Arthritis Rheum (2008) 0.92
Subunit-specific incorporation efficiency and kinetics in mitochondrial complex I homeostasis. J Biol Chem (2012) 0.92
Localization of breast cancer resistance protein (Bcrp) in endocrine organs and inhibition of its transport activity by steroid hormones. Cell Tissue Res (2012) 0.92
Functional role of arginine 375 in transmembrane helix 6 of multidrug resistance protein 4 (MRP4/ABCC4). Mol Pharmacol (2008) 0.91
Interaction of immunosuppressive drugs with human organic anion transporter (OAT) 1 and OAT3, and multidrug resistance-associated protein (MRP) 2 and MRP4. Transl Res (2013) 0.90
Biomarkers for methotrexate-induced liver injury: urinary protein profiling of psoriasis patients. Toxicol Lett (2013) 0.90
Na,K-ATPase activity modulates Src activation: a role for ATP/ADP ratio. Biochim Biophys Acta (2012) 0.89
Effect of drugs on renal development. Clin J Am Soc Nephrol (2010) 0.89
Nitric oxide differentially regulates renal ATP-binding cassette transporters during endotoxemia. Pflugers Arch (2007) 0.89
Endocrine disruptors differentially target ATP-binding cassette transporters in the blood-testis barrier and affect Leydig cell testosterone secretion in vitro. Toxicol Sci (2013) 0.89
AMAP, the alleged non-toxic isomer of acetaminophen, is toxic in rat and human liver. Arch Toxicol (2012) 0.89
Local and remote ischemic postconditionings have synergistic protective effects on renal ischemia-reperfusion injury. Transplantation (2012) 0.88
Tubular reabsorption and local production of urine hepcidin-25. BMC Nephrol (2013) 0.87
Localization of the ATP-binding cassette (ABC) transport proteins PfMRP1, PfMRP2, and PfMDR5 at the Plasmodium falciparum plasma membrane. Malar J (2009) 0.87
Epithelial-to-mesenchymal transition in fibrosis: collagen type I expression is highly upregulated after EMT, but does not contribute to collagen deposition. Exp Cell Res (2013) 0.86
Characterization of P-glycoprotein and multidrug resistance proteins in rat kidney and intestinal cell lines. Eur J Pharm Sci (2006) 0.86
Mesenchymal stem cell-conditioned medium accelerates regeneration of human renal proximal tubule epithelial cells after gentamicin toxicity. Exp Toxicol Pathol (2012) 0.86
Breast cancer resistance protein (Bcrp1/Abcg2) limits net intestinal uptake of quercetin in rats by facilitating apical efflux of glucuronides. Mol Pharmacol (2005) 0.86
Diannexin protects against renal ischemia reperfusion injury and targets phosphatidylserines in ischemic tissue. PLoS One (2011) 0.86
Cannabinoid type 1 receptor antagonists modulate transport activity of multidrug resistance-associated proteins MRP1, MRP2, MRP3, and MRP4. Drug Metab Dispos (2011) 0.86
Insights into the role of bone marrow-derived stem cells in renal repair. Kidney Blood Press Res (2008) 0.86
Short report: Severe Plasmodium falciparum malaria in Cameroon: associated with the glutathione S-transferase M1 null genotype. Am J Trop Med Hyg (2006) 0.86
In silico identification of potential cholestasis-inducing agents via modeling of Na(+)-dependent taurocholate cotransporting polypeptide substrate specificity. Toxicol Sci (2012) 0.86
Involvement of guanylyl cyclase and cGMP in the regulation of Mrp2-mediated transport in the proximal tubule. Am J Physiol Renal Physiol (2004) 0.85
Optimized metabolomic approach to identify uremic solutes in plasma of stage 3-4 chronic kidney disease patients. PLoS One (2013) 0.85
Alkaline phosphatase as a treatment of sepsis-associated acute kidney injury. J Pharmacol Exp Ther (2012) 0.85
Modeling mitochondrial dysfunctions in the brain: from mice to men. J Inherit Metab Dis (2011) 0.84
Role of NO in endothelin-regulated drug transport in the renal proximal tubule. Am J Physiol Renal Physiol (2002) 0.84
Short-term beneficial effects of methylene blue on kidney damage in septic shock patients. Intensive Care Med (2007) 0.84
Glibenclamide depletes ATP in renal proximal tubular cells by interfering with mitochondrial metabolism. Br J Pharmacol (2005) 0.84
Short- and long-term influences of heavy metals on anionic drug efflux from renal proximal tubule. J Pharmacol Exp Ther (2002) 0.84
Vitamin A equivalency and apparent absorption of beta-carotene in ileostomy subjects using a dual-isotope dilution technique. Br J Nutr (2010) 0.84
Therapeutic implications of renal anionic drug transporters. Pharmacol Ther (2010) 0.84
Regulatory pathways for ATP-binding cassette transport proteins in kidney proximal tubules. AAPS J (2012) 0.83
Function and regulation of multidrug resistance proteins (MRPs) in the renal elimination of organic anions. Drug Metab Rev (2005) 0.83
Interaction of fluvastatin with the liver-specific Na+ -dependent taurocholate cotransporting polypeptide (NTCP). Eur J Pharm Sci (2011) 0.83
First reported use of elvitegravir and cobicistat during pregnancy. AIDS (2016) 0.82
Short-term exposure of renal proximal tubules to gentamicin increases long-term multidrug resistance protein 2 (Abcc2) transport function and reduces nephrotoxicant sensitivity. J Pharmacol Exp Ther (2005) 0.82
Hypothermia causes a marked injury to rat proximal tubular cells that is aggravated by all currently used preservation solutions. Cryobiology (2003) 0.82
Increased apical insertion of the multidrug resistance protein 2 (MRP2/ABCC2) in renal proximal tubules following gentamicin exposure. J Pharmacol Exp Ther (2006) 0.81
Transport of a fluorescent cAMP analog in teleost proximal tubules. Am J Physiol Regul Integr Comp Physiol (2007) 0.81