Published in J Cell Biol on September 15, 2008
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The epithelial splicing factors ESRP1 and ESRP2 positively and negatively regulate diverse types of alternative splicing events. RNA Biol (2009) 1.57
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Human axonal survival of motor neuron (a-SMN) protein stimulates axon growth, cell motility, C-C motif ligand 2 (CCL2), and insulin-like growth factor-1 (IGF1) production. J Biol Chem (2012) 0.84
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A novel role for p120 catenin in E-cadherin function. J Cell Biol (2002) 4.01
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The adaptor protein paxillin is essential for normal development in the mouse and is a critical transducer of fibronectin signaling. Mol Cell Biol (2002) 2.73
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Disassembling adherens junctions: breaking up is hard to do. Trends Cell Biol (2005) 2.00
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Protein 4.1 tumor suppressors: getting a FERM grip on growth regulation. J Cell Sci (2002) 1.59
A new paxillin-binding protein, PAG3/Papalpha/KIAA0400, bearing an ADP-ribosylation factor GTPase-activating protein activity, is involved in paxillin recruitment to focal adhesions and cell migration. Mol Biol Cell (2000) 1.51
Requirement for Arf6 in cell adhesion, migration, and cancer cell invasion. J Biochem (2003) 1.50
Role of p120-catenin in cadherin trafficking. Biochim Biophys Acta (2006) 1.44
A novel member of the NF2/ERM/4.1 superfamily with growth suppressing properties in lung cancer. Cancer Res (1999) 1.44
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TGF-beta signaling-mediated morphogenesis: modulation of cell adhesion via cadherin endocytosis. Genes Dev (2007) 1.32
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Zebrafish mosaic eyes is a novel FERM protein required for retinal lamination and retinal pigmented epithelial tight junction formation. Curr Biol (2004) 1.25
The FERM protein Epb4.1l5 is required for organization of the neural plate and for the epithelial-mesenchymal transition at the primitive streak of the mouse embryo. Development (2007) 1.21
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FERM protein EPB41L5 is a novel member of the mammalian CRB-MPP5 polarity complex. Exp Cell Res (2007) 1.02
Interaction of integrin alpha(v)beta3 with nectin. Implication in cross-talk between cell-matrix and cell-cell junctions. J Biol Chem (2006) 1.00
Wnt signalling regulates paxillin ubiquitination essential for mesodermal cell motility. Nat Cell Biol (2007) 1.00
Local and transient expression of E-cadherin involved in mouse embryonic brain morphogenesis. Development (1992) 0.98
Reassignment of the EPB4.1 gene to 1p36 and assessment of its involvement in neuroblastomas. Eur J Clin Invest (2001) 0.81
Self-organized formation of polarized cortical tissues from ESCs and its active manipulation by extrinsic signals. Cell Stem Cell (2008) 5.40
Self-formation of optic cups and storable stratified neural retina from human ESCs. Cell Stem Cell (2012) 3.85
Notch2 is preferentially expressed in mature B cells and indispensable for marginal zone B lineage development. Immunity (2003) 3.73
Bcl11b is required for differentiation and survival of alphabeta T lymphocytes. Nat Immunol (2003) 3.42
Experience-dependent transfer of Otx2 homeoprotein into the visual cortex activates postnatal plasticity. Cell (2008) 3.32
Differentiation of embryonic stem cells is induced by GATA factors. Genes Dev (2002) 3.12
Otx2 homeobox gene controls retinal photoreceptor cell fate and pineal gland development. Nat Neurosci (2003) 3.08
Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranes. Nat Genet (2002) 3.06
Hippo pathway regulation by cell morphology and stress fibers. Development (2011) 2.94
Terminal axon branching is regulated by the LKB1-NUAK1 kinase pathway via presynaptic mitochondrial capture. Cell (2013) 2.92
Cthrc1 selectively activates the planar cell polarity pathway of Wnt signaling by stabilizing the Wnt-receptor complex. Dev Cell (2008) 2.89
GEP100 links epidermal growth factor receptor signalling to Arf6 activation to induce breast cancer invasion. Nat Cell Biol (2007) 2.88
Glucokinase and IRS-2 are required for compensatory beta cell hyperplasia in response to high-fat diet-induced insulin resistance. J Clin Invest (2007) 2.81
Modulating F-actin organization induces organ growth by affecting the Hippo pathway. EMBO J (2011) 2.75
Shisa promotes head formation through the inhibition of receptor protein maturation for the caudalizing factors, Wnt and FGF. Cell (2005) 2.61
Polarized transport of Frizzled along the planar microtubule arrays in Drosophila wing epithelium. Dev Cell (2006) 2.47
Centralspindlin regulates ECT2 and RhoA accumulation at the equatorial cortex during cytokinesis. J Cell Sci (2005) 2.37
Requirement for Arf6 in breast cancer invasive activities. Proc Natl Acad Sci U S A (2004) 2.37
Self-formation of functional adenohypophysis in three-dimensional culture. Nature (2011) 2.34
Cdc42 and mDia3 regulate microtubule attachment to kinetochores. Nature (2004) 2.15
MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci (2011) 2.03
Roles played by a subset of integrin signaling molecules in cadherin-based cell-cell adhesion. J Cell Biol (2004) 2.02
Actomyosin tension is required for correct recruitment of adherens junction components and zonula occludens formation. Exp Cell Res (2006) 1.91
Characterization of the pufferfish Otx2 cis-regulators reveals evolutionarily conserved genetic mechanisms for vertebrate head specification. Development (2003) 1.90
Localized suppression of RhoA activity by Tyr31/118-phosphorylated paxillin in cell adhesion and migration. J Cell Biol (2002) 1.78
MicroRNA-9 modulates Cajal-Retzius cell differentiation by suppressing Foxg1 expression in mouse medial pallium. J Neurosci (2008) 1.77
A stream of cells migrating from the caudal telencephalon reveals a link between the amygdala and neocortex. Nat Neurosci (2007) 1.76
RNF5, a RING finger protein that regulates cell motility by targeting paxillin ubiquitination and altered localization. Mol Cell Biol (2003) 1.75
Structural basis of adhesion-molecule recognition by ERM proteins revealed by the crystal structure of the radixin-ICAM-2 complex. EMBO J (2003) 1.70
Expression of AMAP1, an ArfGAP, provides novel targets to inhibit breast cancer invasive activities. EMBO J (2005) 1.69
HSF4 is required for normal cell growth and differentiation during mouse lens development. EMBO J (2004) 1.69
Establishment of conditional reporter mouse lines at ROSA26 locus for live cell imaging. Genesis (2011) 1.54
Regulation of myosin II dynamics by phosphorylation and dephosphorylation of its light chain in epithelial cells. Mol Biol Cell (2006) 1.51
Functional roles of Otx2 transcription factor in postnatal mouse retinal development. Mol Cell Biol (2007) 1.46
Interaction between PAR-3 and the aPKC-PAR-6 complex is indispensable for apical domain development of epithelial cells. J Cell Sci (2009) 1.45
New roles for the LKB1-NUAK pathway in controlling myosin phosphatase complexes and cell adhesion. Sci Signal (2010) 1.43
Canonical Wnt signaling and its antagonist regulate anterior-posterior axis polarization by guiding cell migration in mouse visceral endoderm. Dev Cell (2005) 1.43
Diminished Ret expression compromises neuronal survival in the colon and causes intestinal aganglionosis in mice. J Clin Invest (2008) 1.43
The c-Jun N-terminal kinase activator dual leucine zipper kinase regulates axon growth and neuronal migration in the developing cerebral cortex. J Neurosci (2006) 1.40
E-cadherin is required for gastrulation cell movements in zebrafish. Mech Dev (2005) 1.38
b-series Ganglioside deficiency exhibits no definite changes in the neurogenesis and the sensitivity to Fas-mediated apoptosis but impairs regeneration of the lesioned hypoglossal nerve. J Biol Chem (2001) 1.38
Three inhibitors of FGF receptor, ERK, and GSK3 establishes germline-competent embryonic stem cells of C57BL/6N mouse strain with high efficiency and stability. Genesis (2010) 1.34
Circadian regulation of intracellular G-protein signalling mediates intercellular synchrony and rhythmicity in the suprachiasmatic nucleus. Nat Commun (2011) 1.34
Generation of trans-mitochondrial mice carrying homoplasmic mtDNAs with a missense mutation in a structural gene using ES cells. Hum Mol Genet (2006) 1.32
Paxillin associates with poly(A)-binding protein 1 at the dense endoplasmic reticulum and the leading edge of migrating cells. J Biol Chem (2001) 1.31
The EGFR-GEP100-Arf6-AMAP1 signaling pathway specific to breast cancer invasion and metastasis. Traffic (2009) 1.31
EphA2 engages Git1 to suppress Arf6 activity modulating epithelial cell-cell contacts. Mol Biol Cell (2009) 1.30
NMII forms a contractile transcellular sarcomeric network to regulate apical cell junctions and tissue geometry. Curr Biol (2013) 1.29
Targeting AMAP1 and cortactin binding bearing an atypical src homology 3/proline interface for prevention of breast cancer invasion and metastasis. Proc Natl Acad Sci U S A (2006) 1.28
Sfrp1 and Sfrp2 regulate anteroposterior axis elongation and somite segmentation during mouse embryogenesis. Development (2006) 1.25
Apical accumulation of Rho in the neural plate is important for neural plate cell shape change and neural tube formation. Mol Biol Cell (2008) 1.24
Sfrp1, Sfrp2, and Sfrp5 regulate the Wnt/beta-catenin and the planar cell polarity pathways during early trunk formation in mouse. Genesis (2008) 1.21
Neutrophil direction sensing and superoxide production linked by the GTPase-activating protein GIT2. Nat Immunol (2006) 1.21
Grainyhead-related transcription factor is required for duct maturation in the salivary gland and the kidney of the mouse. Development (2006) 1.20
Conditional ablation of GFRalpha1 in postmigratory enteric neurons triggers unconventional neuronal death in the colon and causes a Hirschsprung's disease phenotype. Development (2007) 1.20
Sfrp controls apicobasal polarity and oriented cell division in developing gut epithelium. PLoS Genet (2009) 1.19
Mammalian Fat and Dachsous cadherins regulate apical membrane organization in the embryonic cerebral cortex. J Cell Biol (2009) 1.19
Regulation of Otx2 expression and its functions in mouse forebrain and midbrain. Development (2004) 1.17
Targeted disruption of the mouse ELYS gene results in embryonic death at peri-implantation development. Genes Cells (2004) 1.17
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CIN85, a Cbl-interacting protein, is a component of AMAP1-mediated breast cancer invasion machinery. EMBO J (2007) 1.14
Visualization of cell cycle in mouse embryos with Fucci2 reporter directed by Rosa26 promoter. Development (2012) 1.13
Regulation of Otx2 expression and its functions in mouse epiblast and anterior neuroectoderm. Development (2004) 1.13
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Rab5c promotes AMAP1-PRKD2 complex formation to enhance β1 integrin recycling in EGF-induced cancer invasion. J Cell Biol (2012) 1.12
ArfGAP family proteins in cell adhesion, migration and tumor invasion. Curr Opin Cell Biol (2006) 1.12
Epithelial cell-intrinsic Notch signaling plays an essential role in the maintenance of gut immune homeostasis. J Immunol (2012) 1.10
Lack of insulin receptor substrate-2 causes progressive neointima formation in response to vessel injury. Circulation (2003) 1.09
Dkk3-Cre BAC transgenic mouse line: a tool for highly efficient gene deletion in retinal progenitor cells. Genesis (2007) 1.08
Interaction of paxillin with poly(A)-binding protein 1 and its role in focal adhesion turnover and cell migration. Mol Cell Biol (2005) 1.08
A novel mode of action of an ArfGAP, AMAP2/PAG3/Papa lpha, in Arf6 function. J Biol Chem (2004) 1.08
Mib-Jag1-Notch signalling regulates patterning and structural roles of the notochord by controlling cell-fate decisions. Development (2010) 1.07
The neurotrophic effects of glial cell line-derived neurotrophic factor on spinal motoneurons are restricted to fusimotor subtypes. J Neurosci (2008) 1.07
The TRPV4 channel contributes to intercellular junction formation in keratinocytes. J Biol Chem (2010) 1.07
Evolutionary constraint on Otx2 neuroectoderm enhancers-deep conservation from skate to mouse and unique divergence in teleost. Proc Natl Acad Sci U S A (2006) 1.06
Heat shock transcription factor 1 is required for maintenance of ciliary beating in mice. J Biol Chem (2007) 1.05
A B-Myb complex containing clathrin and filamin is required for mitotic spindle function. EMBO J (2008) 1.05
An essential role for RAX homeoprotein and NOTCH-HES signaling in Otx2 expression in embryonic retinal photoreceptor cell fate determination. J Neurosci (2011) 1.05
Zyxin mediates actin fiber reorganization in epithelial-mesenchymal transition and contributes to endocardial morphogenesis. Mol Biol Cell (2009) 1.04
GFRalpha1 expression in cells lacking RET is dispensable for organogenesis and nerve regeneration. Neuron (2004) 1.04
Specialized extraembryonic cells connect embryonic and extraembryonic epidermis in response to Dpp during dorsal closure in Drosophila. Dev Biol (2006) 1.03
Changes in temperature preferences and energy homeostasis in dystroglycan mutants. Science (2009) 1.03
Regulation of Bin1 SH3 domain binding by phosphoinositides. EMBO J (2004) 1.03
Trichoplein and Aurora A block aberrant primary cilia assembly in proliferating cells. J Cell Biol (2012) 1.03
Genetic modifiers of otocephalic phenotypes in Otx2 heterozygous mutant mice. Development (2002) 1.02
Clathrin dependent endocytosis of E-cadherin is regulated by the Arf6GAP isoform SMAP1. Exp Cell Res (2007) 1.01
Otx2 is required to respond to signals from anterior neural ridge for forebrain specification. Dev Biol (2002) 1.01
GEP100-Arf6-AMAP1-cortactin pathway frequently used in cancer invasion is activated by VEGFR2 to promote angiogenesis. PLoS One (2011) 1.00
Emx1 and Emx2 cooperate in initial phase of archipallium development. Mech Dev (2004) 1.00
The keratin-binding protein Albatross regulates polarization of epithelial cells. J Cell Biol (2008) 0.99
Ultraviolet A-induced production of matrix metalloproteinase-1 is mediated by macrophage migration inhibitory factor (MIF) in human dermal fibroblasts. J Biol Chem (2003) 0.99
Maintenance of olfactory neurogenesis requires HSF1, a major heat shock transcription factor in mice. J Biol Chem (2005) 0.99