Published in J Immunol on October 01, 2008
Sugar administration is an effective adjunctive therapy in the treatment of Pseudomonas aeruginosa pneumonia. Am J Physiol Lung Cell Mol Physiol (2013) 2.04
Cytotoxic cells kill intracellular bacteria through granulysin-mediated delivery of granzymes. Cell (2014) 1.76
Innate immune responses to Pseudomonas aeruginosa infection. Microbes Infect (2011) 1.33
A fusion protein vaccine containing OprF epitope 8, OprI, and type A and B flagellins promotes enhanced clearance of nonmucoid Pseudomonas aeruginosa. Infect Immun (2009) 1.12
Cathepsin G and neutrophil elastase play critical and nonredundant roles in lung-protective immunity against Streptococcus pneumoniae in mice. Infect Immun (2011) 1.06
Human neutrophil elastase degrades SPLUNC1 and impairs airway epithelial defense against bacteria. PLoS One (2013) 0.88
Neutrophil elastase modulates cytokine expression: contribution to host defense against Pseudomonas aeruginosa-induced pneumonia. J Biol Chem (2012) 0.85
Changes in bowel microbiota induced by feeding weanlings resistant starch stimulate transcriptomic and physiological responses. Appl Environ Microbiol (2012) 0.83
Thrombospondin-1 restrains neutrophil granule serine protease function and regulates the innate immune response during Klebsiella pneumoniae infection. Mucosal Immunol (2014) 0.83
Neutrophil elastase and matrix metalloproteinase 12 in cystic fibrosis lung disease. Mol Cell Pediatr (2016) 0.82
Neutrophil proteinase 3 acts on protease-activated receptor-2 to enhance vascular endothelial cell barrier function. Arterioscler Thromb Vasc Biol (2012) 0.78
The landscape of protein biomarkers proposed for periodontal disease: markers with functional meaning. Biomed Res Int (2014) 0.78
Why is Pseudomonas aeruginosa a pathogen? F1000 Biol Rep (2010) 0.78
Toll-Like Receptor 4 Agonistic Antibody Promotes Host Defense against Chronic Pseudomonas aeruginosa Lung Infection in Mice. Infect Immun (2016) 0.76
Neutrophil elastase cleaves epithelial cadherin in acutely injured lung epithelium. Respir Res (2016) 0.75
The neutrophil elastase inhibitor, sivelestat, attenuates sepsis-related kidney injury in rats. Int J Mol Med (2016) 0.75
Interactions between Neutrophils and Pseudomonas aeruginosa in Cystic Fibrosis. Pathogens (2017) 0.75
Neutrophil Fates in Bronchiectasis and Alpha-1 Antitrypsin Deficiency. Ann Am Thorac Soc (2016) 0.75
Paucimannose-Rich N-glycosylation of Spatiotemporally Regulated Human Neutrophil Elastase Modulates Its Immune Functions. Mol Cell Proteomics (2017) 0.75
Fluorescence lifetime measurements and biological imaging. Chem Rev (2010) 3.99
Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin. J Clin Invest (2008) 2.77
Whole-body fluorescence lifetime imaging of a tumor-targeted near-infrared molecular probe in mice. J Biomed Opt (2005) 2.14
Granulomatosis-associated common variable immunodeficiency disorder: a case-control study versus sarcoidosis. Eur Respir J (2012) 2.11
Preparation and biological evaluation of copper-64-labeled tyr3-octreotate using a cross-bridged macrocyclic chelator. Clin Cancer Res (2004) 1.89
Multimodality molecular imaging with combined optical and SPECT/PET modalities. J Nucl Med (2008) 1.83
Endobronchial actinomycosis associated with foreign body: four cases and a review of the literature. Chest (2002) 1.83
Time-dependent whole-body fluorescence tomography of probe bio-distributions in mice. Opt Express (2005) 1.73
Near infrared dyes as lifetime solvatochromic probes for micropolarity measurements of biological systems. Biophys J (2007) 1.71
Design, synthesis, and evaluation of near infrared fluorescent multimeric RGD peptides for targeting tumors. J Med Chem (2006) 1.71
Heptamethine cyanine dyes with a robust C-C bond at the central position of the chromophore. J Org Chem (2006) 1.68
Handheld array-based photoacoustic probe for guiding needle biopsy of sentinel lymph nodes. J Biomed Opt (2010) 1.65
Hands-free, wireless goggles for near-infrared fluorescence and real-time image-guided surgery. Surgery (2011) 1.60
In vivo fluorescence lifetime tomography. J Biomed Opt (2009) 1.55
Noninvasive photoacoustic and fluorescence sentinel lymph node identification using dye-loaded perfluorocarbon nanoparticles. ACS Nano (2010) 1.53
Epidemiological, molecular, and clinical features of enterovirus respiratory infections in French children between 1999 and 2005. J Clin Microbiol (2007) 1.46
Complementary optical and nuclear imaging of caspase-3 activity using combined activatable and radio-labeled multimodality molecular probe. J Biomed Opt (2009) 1.40
Endoscopic management of idiopathic tracheal stenosis. Ann Thorac Surg (2011) 1.40
Optical imaging of mammary and prostate tumors in living animals using a synthetic near infrared zinc(II)-dipicolylamine probe for anionic cell surfaces. J Am Chem Soc (2010) 1.34
Synthesis and characterization of a macrocyclic near-infrared optical scaffold. J Am Chem Soc (2003) 1.33
Biodegradable pH-sensing dendritic nanoprobes for near-infrared fluorescence lifetime and intensity imaging. J Am Chem Soc (2007) 1.30
Monomolecular multimodal fluorescence-radioisotope imaging agents. Bioconjug Chem (2005) 1.30
Near-infrared fluorescence goggle system with complementary metal-oxide-semiconductor imaging sensor and see-through display. J Biomed Opt (2013) 1.27
A novel approach to a bifunctional photosensitizer for tumor imaging and phototherapy. Bioconjug Chem (2005) 1.20
In vivo resolution of multiexponential decays of multiple near-infrared molecular probes by fluorescence lifetime-gated whole-body time-resolved diffuse optical imaging. Mol Imaging (2007) 1.19
Predicting in vivo fluorescence lifetime behavior of near-infrared fluorescent contrast agents using in vitro measurements. J Biomed Opt (2008) 1.18
Fluorescence lifetime properties of near-infrared cyanine dyes in relation to their structures. J Photochem Photobiol A Chem (2008) 1.16
The role of matrix metalloproteinase-9 in cigarette smoke-induced emphysema. Am J Respir Crit Care Med (2010) 1.16
Gold nanocages covered with thermally-responsive polymers for controlled release by high-intensity focused ultrasound. Nanoscale (2011) 1.15
(64)Cu-labeled CB-TE2A and diamsar-conjugated RGD peptide analogs for targeting angiogenesis: comparison of their biological activity. Nucl Med Biol (2009) 1.14
Ratiometric analysis of fluorescence lifetime for probing binding sites in albumin with near-infrared fluorescent molecular probes. Photochem Photobiol (2007) 1.14
Synthesis and evaluation of polyhydroxylated near-infrared carbocyanine molecular probes. Org Lett (2004) 1.14
Multivalent carbocyanine molecular probes: synthesis and applications. Bioconjug Chem (2005) 1.13
Activatable molecular systems using homologous near-infrared fluorescent probes for monitoring enzyme activities in vitro, in cellulo, and in vivo. Mol Pharm (2009) 1.13
Noninvasive imaging of osteoclasts in parathyroid hormone-induced osteolysis using a 64Cu-labeled RGD peptide. J Nucl Med (2007) 1.10
Preparation and biological evaluation of 64Cu-CB-TE2A-sst2-ANT, a somatostatin antagonist for PET imaging of somatostatin receptor-positive tumors. J Nucl Med (2008) 1.10
Agonist-antagonist dilemma in molecular imaging: evaluation of a monomolecular multimodal imaging agent for the somatostatin receptor. Bioconjug Chem (2007) 1.09
Video-rate fluorescence diffuse optical tomography for in vivo sentinel lymph node imaging. Biomed Opt Express (2011) 1.09
Myeloperoxidase plays critical roles in killing Klebsiella pneumoniae and inactivating neutrophil elastase: effects on host defense. J Immunol (2005) 1.09
In vivo targeted deep-tissue photodynamic therapy based on near-infrared light triggered upconversion nanoconstruct. ACS Nano (2012) 1.08
Broad-spectrum peptide inhibitors of aminoglycoside antibiotic resistance enzymes. Chem Biol (2003) 1.08
Temporal patterns of the cerebral inflammatory response in the rat lithium-pilocarpine model of temporal lobe epilepsy. Neurobiol Dis (2004) 1.07
Detection of enzyme activity in orthotopic murine breast cancer by fluorescence lifetime imaging using a fluorescence resonance energy transfer-based molecular probe. J Biomed Opt (2011) 1.05
Multiphoton microscopy with near infrared contrast agents. J Biomed Opt (2010) 1.05
Rational approach to select small peptide molecular probes labeled with fluorescent cyanine dyes for in vivo optical imaging. Biochemistry (2011) 1.04
Dynamic noninvasive monitoring of renal function in vivo by fluorescence lifetime imaging. J Biomed Opt (2009) 1.04
Neutrophil elastase degrades cystic fibrosis transmembrane conductance regulator via calpains and disables channel function in vitro and in vivo. Am J Respir Crit Care Med (2012) 1.03
Therapeutic management of broncholithiasis. Ann Thorac Surg (2005) 1.02
Near-infrared pH-activatable fluorescent probes for imaging primary and metastatic breast tumors. Bioconjug Chem (2011) 1.02
Structural characterization of mouse neutrophil serine proteases and identification of their substrate specificities: relevance to mouse models of human inflammatory diseases. J Biol Chem (2009) 1.01
Influence of CD14 on ligand interactions between lipopolysaccharide and its receptor complex. J Immunol (2005) 1.01
Metalloproteinase and cytokine production by THP-1 macrophages following exposure to chitosan-DNA nanoparticles. Biomaterials (2005) 1.01
Folate-modified gold nanoclusters as near-infrared fluorescent probes for tumor imaging and therapy. Nanoscale (2012) 1.01
Design, synthesis and evaluation of near-infrared fluorescent pH indicators in a physiologically relevant range. Chem Commun (Camb) (2005) 1.01
Relative contribution of NF-kappaB and AP-1 in the modulation by curcumin and pyrrolidine dithiocarbamate of the UVB-induced cytokine expression by keratinocytes. Cytokine (2002) 1.01
Perspectives and potential applications of nanomedicine in breast and prostate cancer. Med Res Rev (2010) 1.00
In vitro and in vivo evaluation of 64Cu-labeled SarAr-bombesin analogs in gastrin-releasing peptide receptor-expressing prostate cancer. J Nucl Med (2011) 1.00
Monitoring the biodegradation of dendritic near-infrared nanoprobes by in vivo fluorescence imaging. Mol Pharm (2009) 1.00
Modifying the protease, antiprotease pattern by elafin overexpression protects mice from colitis. Gastroenterology (2011) 0.99
Involvement of toll-like receptor 4 in the inflammatory reaction induced by hydroxyapatite particles. Biomaterials (2006) 0.99
Near infrared-fluorescent and magnetic resonance imaging molecular probe with high T1 relaxivity for in vivo multimodal imaging. Chem Commun (Camb) (2010) 0.99
Importance of hydroxyapatite particles characteristics on cytokines production by human monocytes in vitro. Biomaterials (2003) 0.99
Bright fluorescent nanoparticles for developing potential optical imaging contrast agents. Nanoscale (2010) 0.98
Polyvalent carbocyanine molecular beacons for molecular recognitions. J Am Chem Soc (2004) 0.98
Activatable probes based on distance-dependent luminescence associated with Cerenkov radiation. Angew Chem Int Ed Engl (2013) 0.98
Contrasting transcriptional responses of a virulent and an attenuated strain of Mycobacterium tuberculosis infecting macrophages. PLoS One (2010) 0.98
Fluorescence manipulation by gold nanoparticles: from complete quenching to extensive enhancement. J Nanobiotechnology (2011) 0.97
Detection of multiple viral and bacterial infections in acute exacerbation of chronic obstructive pulmonary disease: a pilot prospective study. J Med Virol (2013) 0.97
Defining a polymethine dye for fluorescence anisotropy applications in the near-infrared spectral range. Chemphyschem (2012) 0.97
Multifunctional gold nanostar conjugates for tumor imaging and combined photothermal and chemo-therapy. Theranostics (2013) 0.97
Novel near-infrared fluorescent integrin-targeted DFO analogue. Bioconjug Chem (2007) 0.96
Inactivation of enveloped virus by laser-driven protein aggregation. J Biomed Opt (2012) 0.96
Detection of MMP-2 and MMP-9 activity in vivo with a triple-helical peptide optical probe. Bioconjug Chem (2012) 0.96
A pH-sensitive doxorubicin prodrug based on folate-conjugated BSA for tumor-targeted drug delivery. Biomaterials (2013) 0.96
Targeting of alpha(nu)beta(3)-integrins expressed on tumor tissue and neovasculature using fluorescent small molecules and nanoparticles. Nanomedicine (Lond) (2010) 0.95
Effect of BMAP-28 antimicrobial peptides on Leishmania major promastigote and amastigote growth: role of leishmanolysin in parasite survival. PLoS Negl Trop Dis (2011) 0.95
In vivo fluorescence lifetime imaging monitors binding of specific probes to cancer biomarkers. PLoS One (2012) 0.94
Spectral properties of pro-multimodal imaging agents derived from a NIR dye and a metal chelator. Photochem Photobiol (2005) 0.94
In vitro and in vivo investigation of matrix metalloproteinase expression in metastatic tumor models. Nucl Med Biol (2006) 0.94
Toll-like receptors and immune response in allergic disease. Clin Rev Allergy Immunol (2004) 0.94
Long fluorescence lifetime molecular probes based on near infrared pyrrolopyrrole cyanine fluorophores for in vivo imaging. Biophys J (2009) 0.94
Siderophore-promoted dissolution of smectite by fluorescent Pseudomonas. Environ Microbiol Rep (2014) 0.93
T cell chemotaxis and chemokine release after Staphylococcus aureus interaction with polarized airway epithelium. Am J Respir Cell Mol Biol (2005) 0.92
Human airway smooth muscle cells express the high affinity receptor for IgE (Fc epsilon RI): a critical role of Fc epsilon RI in human airway smooth muscle cell function. J Immunol (2005) 0.92
Myeloperoxidase-dependent inactivation of surfactant protein D in vitro and in vivo. J Biol Chem (2010) 0.92
Description of tobacco addiction in pregnant women. Eur J Obstet Gynecol Reprod Biol (2005) 0.92
Near-infrared dichromic fluorescent carbocyanine molecules. Angew Chem Int Ed Engl (2008) 0.92
alpha3alpha5beta2-Nicotinic acetylcholine receptor contributes to the wound repair of the respiratory epithelium by modulating intracellular calcium in migrating cells. Am J Pathol (2006) 0.92
Pathogen-induced expression of a cecropin A-melittin antimicrobial peptide gene confers antifungal resistance in transgenic tobacco. J Exp Bot (2005) 0.91
Intravenous application of CD271-selected mesenchymal stem cells during fracture healing. J Orthop Trauma (2014) 0.90
Elastin fragments induce IL-1beta upregulation via NF-kappaB pathway in melanoma cells. J Invest Dermatol (2006) 0.90
Synthesis and spectral properties of near-infrared aminophenyl-, hydroxyphenyl-, and phenyl-substituted heptamethine cyanines. J Org Chem (2007) 0.90
Near-infrared fluorescence lifetime pH-sensitive probes. Biophys J (2011) 0.90
Introduction to concepts and strategies for molecular imaging. Chem Rev (2010) 0.89