Published in Int J Biochem Cell Biol on September 02, 2008
TNF/p38α/polycomb signaling to Pax7 locus in satellite cells links inflammation to the epigenetic control of muscle regeneration. Cell Stem Cell (2010) 2.89
Oxygen consumption and usage during physical exercise: the balance between oxidative stress and ROS-dependent adaptive signaling. Antioxid Redox Signal (2012) 1.60
Chromatin: the interface between extrinsic cues and the epigenetic regulation of muscle regeneration. Trends Cell Biol (2009) 1.49
Fibroadipogenic progenitors mediate the ability of HDAC inhibitors to promote regeneration in dystrophic muscles of young, but not old Mdx mice. EMBO Mol Med (2013) 1.16
Sphingosine-1-phosphate enhances satellite cell activation in dystrophic muscles through a S1PR2/STAT3 signaling pathway. PLoS One (2012) 1.06
Histone deacetylase inhibitors in the treatment of muscular dystrophies: epigenetic drugs for genetic diseases. Mol Med (2011) 1.06
HDAC-regulated myomiRs control BAF60 variant exchange and direct the functional phenotype of fibro-adipogenic progenitors in dystrophic muscles. Genes Dev (2014) 1.03
Sculpting chromatin beyond the double helix: epigenetic control of skeletal myogenesis. Curr Top Dev Biol (2011) 0.95
Preclinical studies in the mdx mouse model of duchenne muscular dystrophy with the histone deacetylase inhibitor givinostat. Mol Med (2013) 0.92
Comparative Genomics of X-linked Muscular Dystrophies: The Golden Retriever Model. Curr Genomics (2013) 0.90
Combined effect of AMPK/PPAR agonists and exercise training in mdx mice functional performance. PLoS One (2012) 0.89
The pharmacology of regenerative medicine. Pharmacol Rev (2013) 0.83
Genome Engineering of Stem Cells for Autonomously Regulated, Closed-Loop Delivery of Biologic Drugs. Stem Cell Reports (2017) 0.81
"Mix of Mics"- Phenotypic and Biological Heterogeneity of "Multipotent" Muscle Interstitial Cells (MICs). J Stem Cell Res Ther (2012) 0.79
Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member. Nature (1997) 14.82
Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy. Cell (2004) 11.33
Regulation and function of IKK and IKK-related kinases. Sci STKE (2006) 8.98
Asymmetric self-renewal and commitment of satellite stem cells in muscle. Cell (2007) 8.05
The circuitry of a master switch: Myod and the regulation of skeletal muscle gene transcription. Development (2005) 8.04
Myostatin mutation associated with gross muscle hypertrophy in a child. N Engl J Med (2004) 7.80
Stem cell function, self-renewal, and behavioral heterogeneity of cells from the adult muscle satellite cell niche. Cell (2005) 7.15
Double muscling in cattle due to mutations in the myostatin gene. Proc Natl Acad Sci U S A (1997) 6.72
Regulation of myostatin activity and muscle growth. Proc Natl Acad Sci U S A (2001) 6.38
Mesoangioblast stem cells ameliorate muscle function in dystrophic dogs. Nature (2006) 5.83
The regulation of Notch signaling controls satellite cell activation and cell fate determination in postnatal myogenesis. Dev Cell (2002) 5.70
Pericytes of human skeletal muscle are myogenic precursors distinct from satellite cells. Nat Cell Biol (2007) 5.50
Angiotensin II type 1 receptor blockade attenuates TGF-beta-induced failure of muscle regeneration in multiple myopathic states. Nat Med (2007) 5.25
Isolation of adult mouse myogenic progenitors: functional heterogeneity of cells within and engrafting skeletal muscle. Cell (2004) 5.20
Functional improvement of dystrophic muscle by myostatin blockade. Nature (2002) 5.10
Highly efficient, functional engraftment of skeletal muscle stem cells in dystrophic muscles. Cell (2008) 4.92
Regulation of muscle mass by myostatin. Annu Rev Cell Dev Biol (2004) 4.69
Post-translational modifications regulating the activity and function of the nuclear factor kappa B pathway. Oncogene (2006) 4.62
Induction of cachexia in mice by systemically administered myostatin. Science (2002) 4.39
Asymmetric division and cosegregation of template DNA strands in adult muscle satellite cells. Nat Cell Biol (2006) 4.33
Pax3 and Pax7 have distinct and overlapping functions in adult muscle progenitor cells. J Cell Biol (2005) 3.96
Stem cells, ageing and the quest for immortality. Nature (2006) 3.89
p38 pathway targets SWI-SNF chromatin-remodeling complex to muscle-specific loci. Nat Genet (2004) 3.87
Biological progression from adult bone marrow to mononucleate muscle stem cell to multinucleate muscle fiber in response to injury. Cell (2002) 3.87
Stem and progenitor cells in skeletal muscle development, maintenance, and therapy. Mol Ther (2007) 3.69
A mutation in the myostatin gene increases muscle mass and enhances racing performance in heterozygote dogs. PLoS Genet (2007) 3.61
IGF-1 induces skeletal myocyte hypertrophy through calcineurin in association with GATA-2 and NF-ATc1. Nature (1999) 3.54
Regulation of muscle growth by multiple ligands signaling through activin type II receptors. Proc Natl Acad Sci U S A (2005) 3.52
Myostatin, a negative regulator of muscle growth, functions by inhibiting myoblast proliferation. J Biol Chem (2000) 3.46
A nitric oxide synthase transgene ameliorates muscular dystrophy in mdx mice. J Cell Biol (2001) 3.41
Myostatin negatively regulates satellite cell activation and self-renewal. J Cell Biol (2003) 3.25
Distinct roles for Pax7 and Pax3 in adult regenerative myogenesis. J Cell Biol (2006) 3.22
Cell therapy of alpha-sarcoglycan null dystrophic mice through intra-arterial delivery of mesoangioblasts. Science (2003) 3.21
Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells. Nature (2008) 3.07
Loss of myostatin attenuates severity of muscular dystrophy in mdx mice. Ann Neurol (2002) 3.03
Interplay of IKK/NF-kappaB signaling in macrophages and myofibers promotes muscle degeneration in Duchenne muscular dystrophy. J Clin Invest (2007) 2.99
p38 and extracellular signal-regulated kinases regulate the myogenic program at multiple steps. Mol Cell Biol (2000) 2.96
Multiple defects and perinatal death in mice deficient in follistatin. Nature (1995) 2.96
A phase I/IItrial of MYO-029 in adult subjects with muscular dystrophy. Ann Neurol (2008) 2.95
Inhibition of myostatin in adult mice increases skeletal muscle mass and strength. Biochem Biophys Res Commun (2003) 2.82
A chronic inflammatory response dominates the skeletal muscle molecular signature in dystrophin-deficient mdx mice. Hum Mol Genet (2002) 2.80
Muscle-specific expression of insulin-like growth factor I counters muscle decline in mdx mice. J Cell Biol (2002) 2.76
Mammalian SWI/SNF complexes promote MyoD-mediated muscle differentiation. Nat Genet (2001) 2.71
Class I histone deacetylases sequentially interact with MyoD and pRb during skeletal myogenesis. Mol Cell (2001) 2.69
Muscle stem cells in development, regeneration, and disease. Genes Dev (2006) 2.67
Activation of latent myostatin by the BMP-1/tolloid family of metalloproteinases. Proc Natl Acad Sci U S A (2003) 2.66
The meso-angioblast: a multipotent, self-renewing cell that originates from the dorsal aorta and differentiates into most mesodermal tissues. Development (2002) 2.50
Quadrupling muscle mass in mice by targeting TGF-beta signaling pathways. PLoS One (2007) 2.41
Functional skeletal muscle regeneration from differentiating embryonic stem cells. Nat Med (2008) 2.38
TGF-beta inhibits muscle differentiation through functional repression of myogenic transcription factors by Smad3. Genes Dev (2001) 2.35
Regulation of muscle regulatory factors by DNA-binding, interacting proteins, and post-transcriptional modifications. J Cell Physiol (2000) 2.33
Long-term enhancement of skeletal muscle mass and strength by single gene administration of myostatin inhibitors. Proc Natl Acad Sci U S A (2008) 2.31
Lack of myostatin results in excessive muscle growth but impaired force generation. Proc Natl Acad Sci U S A (2007) 2.25
Functional and morphological recovery of dystrophic muscles in mice treated with deacetylase inhibitors. Nat Med (2006) 2.25
Regulation of skeletal muscle gene expression by p38 MAP kinases. Trends Cell Biol (2005) 2.23
SIK1 is a class II HDAC kinase that promotes survival of skeletal myocytes. Nat Med (2007) 2.17
Myostatin propeptide-mediated amelioration of dystrophic pathophysiology. FASEB J (2005) 2.14
p38 MAPK signaling regulates recruitment of Ash2L-containing methyltransferase complexes to specific genes during differentiation. Nat Struct Mol Biol (2007) 2.03
Deacetylase inhibitors increase muscle cell size by promoting myoblast recruitment and fusion through induction of follistatin. Dev Cell (2004) 2.01
Molecular mechanisms of muscular dystrophies: old and new players. Nat Rev Mol Cell Biol (2006) 1.99
Signaling chromatin to make muscle. Curr Opin Cell Biol (2002) 1.88
Muscle regeneration in the prolonged absence of myostatin. Proc Natl Acad Sci U S A (2005) 1.81
Serum levels of insulin-like growth factor I and its binding proteins in health and disease. Growth Horm IGF Res (2003) 1.79
IGF-1, inflammation and stem cells: interactions during muscle regeneration. Trends Immunol (2005) 1.79
Local expression of IGF-1 accelerates muscle regeneration by rapidly modulating inflammatory cytokines and chemokines. FASEB J (2007) 1.76
Fibrinogen drives dystrophic muscle fibrosis via a TGFbeta/alternative macrophage activation pathway. Genes Dev (2008) 1.73
Muscular dystrophies: genes to pathogenesis. Curr Opin Genet Dev (2003) 1.71
Functional interdependence at the chromatin level between the MKK6/p38 and IGF1/PI3K/AKT pathways during muscle differentiation. Mol Cell (2007) 1.70
Nitric oxide release combined with nonsteroidal antiinflammatory activity prevents muscular dystrophy pathology and enhances stem cell therapy. Proc Natl Acad Sci U S A (2006) 1.69
Transgenic expression of a myostatin inhibitor derived from follistatin increases skeletal muscle mass and ameliorates dystrophic pathology in mdx mice. FASEB J (2007) 1.65
Age-dependent effect of myostatin blockade on disease severity in a murine model of limb-girdle muscular dystrophy. Am J Pathol (2006) 1.64
Modulating skeletal muscle mass by postnatal, muscle-specific inactivation of the myostatin gene. Genesis (2003) 1.48
Regulation of myogenic progenitor proliferation in human fetal skeletal muscle by BMP4 and its antagonist Gremlin. J Cell Biol (2006) 1.42
PlGF-MMP-9-expressing cells restore microcirculation and efficacy of cell therapy in aged dystrophic muscle. Nat Med (2008) 1.38
Stage-specific modulation of skeletal myogenesis by inhibitors of nuclear deacetylases. Proc Natl Acad Sci U S A (2002) 1.36
The new frontier in muscular dystrophy research: booster genes. FASEB J (2003) 1.29
The epigenetic network regulating muscle development and regeneration. J Cell Physiol (2006) 1.28
Muscular atrophy of caveolin-3-deficient mice is rescued by myostatin inhibition. J Clin Invest (2006) 1.26
Retracted Follistatin induction by nitric oxide through cyclic GMP: a tightly regulated signaling pathway that controls myoblast fusion. J Cell Biol (2006) 1.25
Role of TNF-{alpha} signaling in regeneration of cardiotoxin-injured muscle. Am J Physiol Cell Physiol (2005) 1.24
Myostatin signals through Pax7 to regulate satellite cell self-renewal. Exp Cell Res (2007) 1.24
uPA deficiency exacerbates muscular dystrophy in MDX mice. J Cell Biol (2007) 1.22
Steroids in Duchenne muscular dystrophy: from clinical trials to genomic research. Neuromuscul Disord (2002) 1.21
Reconciling data from transgenic mice that overexpress IGF-I specifically in skeletal muscle. Growth Horm IGF Res (2005) 1.21
The regulation and action of myostatin as a negative regulator of muscle development during avian embryogenesis. Dev Biol (2002) 1.19
Damage and inflammation in muscular dystrophy: potential implications and relationships with autoimmune myositis. Curr Opin Rheumatol (2005) 1.18
Elimination of myostatin does not combat muscular dystrophy in dy mice but increases postnatal lethality. Am J Pathol (2005) 1.15
Reduced muscle necrosis and long-term benefits in dystrophic mdx mice after cV1q (blockade of TNF) treatment. Neuromuscul Disord (2008) 1.09
Inhibiting myostatin with follistatin improves the success of myoblast transplantation in dystrophic mice. Cell Transplant (2008) 0.98
Signaling to the chromatin during skeletal myogenesis: novel targets for pharmacological modulation of gene expression. Semin Cell Dev Biol (2005) 0.96
Insulin-like growth factor action and skeletal muscle growth, an in vivo perspective. Growth Horm IGF Res (2003) 0.89
Sizing up muscular dystrophy. Nat Med (2002) 0.88
Emerging parallels in the generation and regeneration of skeletal muscle. Cell (2003) 0.88
p38 pathway targets SWI-SNF chromatin-remodeling complex to muscle-specific loci. Nat Genet (2004) 3.87
TNF/p38α/polycomb signaling to Pax7 locus in satellite cells links inflammation to the epigenetic control of muscle regeneration. Cell Stem Cell (2010) 2.89
p38-dependent phosphorylation of the mRNA decay-promoting factor KSRP controls the stability of select myogenic transcripts. Mol Cell (2005) 2.38
Deacetylase inhibitors increase muscle cell size by promoting myoblast recruitment and fusion through induction of follistatin. Dev Cell (2004) 2.01
Studying arrhythmogenic right ventricular dysplasia with patient-specific iPSCs. Nature (2013) 2.00
HDAC2 blockade by nitric oxide and histone deacetylase inhibitors reveals a common target in Duchenne muscular dystrophy treatment. Proc Natl Acad Sci U S A (2008) 1.80
Functional interdependence at the chromatin level between the MKK6/p38 and IGF1/PI3K/AKT pathways during muscle differentiation. Mol Cell (2007) 1.70
Signal-dependent incorporation of MyoD-BAF60c into Brg1-based SWI/SNF chromatin-remodelling complex. EMBO J (2011) 1.55
A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell (2009) 1.53
Chromatin: the interface between extrinsic cues and the epigenetic regulation of muscle regeneration. Trends Cell Biol (2009) 1.49
Coordination of cell cycle, DNA repair and muscle gene expression in myoblasts exposed to genotoxic stress. Cell Cycle (2011) 1.47
Stage-specific modulation of skeletal myogenesis by inhibitors of nuclear deacetylases. Proc Natl Acad Sci U S A (2002) 1.36
Activation of MyoD-dependent transcription by cdk9/cyclin T2. Oncogene (2002) 1.33
Differentiation-induced radioresistance in muscle cells. Mol Cell Biol (2004) 1.30
The epigenetic network regulating muscle development and regeneration. J Cell Physiol (2006) 1.28
Phosphorylation-dependent degradation of p300 by doxorubicin-activated p38 mitogen-activated protein kinase in cardiac cells. Mol Cell Biol (2005) 1.27
Epigenetic reprogramming of human embryonic stem cells into skeletal muscle cells and generation of contractile myospheres. Cell Rep (2013) 1.17
Fibroadipogenic progenitors mediate the ability of HDAC inhibitors to promote regeneration in dystrophic muscles of young, but not old Mdx mice. EMBO Mol Med (2013) 1.16
SWI/SNF complexes, chromatin remodeling and skeletal myogenesis: it's time to exchange! Exp Cell Res (2010) 1.10
Histone deacetylase inhibitors in the treatment of muscular dystrophies: epigenetic drugs for genetic diseases. Mol Med (2011) 1.06
Deacetylase recruitment by the C/H3 domain of the acetyltransferase p300. Oncogene (2004) 1.06
The ER-bound RING finger protein 5 (RNF5/RMA1) causes degenerative myopathy in transgenic mice and is deregulated in inclusion body myositis. PLoS One (2008) 1.05
HDAC-regulated myomiRs control BAF60 variant exchange and direct the functional phenotype of fibro-adipogenic progenitors in dystrophic muscles. Genes Dev (2014) 1.03
Epigenetic regulation of skeletal myogenesis. Organogenesis (2010) 1.02
Nitric oxide deficiency determines global chromatin changes in Duchenne muscular dystrophy. FASEB J (2009) 1.00
DNA damage and cellular differentiation: more questions than responses. J Cell Physiol (2007) 0.98
Coordinate Nodal and BMP inhibition directs Baf60c-dependent cardiomyocyte commitment. Genes Dev (2013) 0.96
Signaling to the chromatin during skeletal myogenesis: novel targets for pharmacological modulation of gene expression. Semin Cell Dev Biol (2005) 0.96
MyoD recruits the cdk9/cyclin T2 complex on myogenic-genes regulatory regions. J Cell Physiol (2006) 0.95
Endothelial activation by angiotensin II through NFkappaB and p38 pathways: Involvement of NFkappaB-inducible kinase (NIK), free oxygen radicals, and selective inhibition by aspirin. J Cell Physiol (2003) 0.95
A two-hit mechanism for pre-mitotic arrest of cancer cell proliferation by a polyamide-alkylator conjugate. Cell Cycle (2006) 0.94
Selective control of Pax7 expression by TNF-activated p38α/polycomb repressive complex 2 (PRC2) signaling during muscle satellite cell differentiation. Cell Cycle (2011) 0.93
A novel AMPK-dependent FoxO3A-SIRT3 intramitochondrial complex sensing glucose levels. Cell Mol Life Sci (2013) 0.93
An evolutionarily acquired genotoxic response discriminates MyoD from Myf5, and differentially regulates hypaxial and epaxial myogenesis. EMBO Rep (2011) 0.92
Preclinical studies in the mdx mouse model of duchenne muscular dystrophy with the histone deacetylase inhibitor givinostat. Mol Med (2013) 0.92
SIRT1 signaling as potential modulator of skeletal muscle diseases. Curr Opin Pharmacol (2012) 0.89
Epigenetic control of skeletal muscle regeneration: Integrating genetic determinants and environmental changes. FEBS J (2013) 0.89
Association of ataxia telangiectasia mutated (ATM) gene mutation/deletion with rhabdomyosarcoma. Cancer Biol Ther (2003) 0.87
Phosphoryl-EZH-ion. Cell Stem Cell (2011) 0.84
Pharmacological inhibition of EZH2 as a promising differentiation therapy in embryonal RMS. BMC Cancer (2014) 0.83
Myosin phosphatase modulates the cardiac cell fate by regulating the subcellular localization of Nkx2.5 in a Wnt/Rho-associated protein kinase-dependent pathway. Circ Res (2012) 0.82
Epigenetic drugs in the treatment of skeletal muscle atrophy. Curr Opin Clin Nutr Metab Care (2008) 0.80
Differentiation of human rhabdomyosarcoma RD cells is regulated by reciprocal, functional interactions between myostatin, p38 and extracellular regulated kinase signalling pathways. Eur J Cancer (2011) 0.79
HDACs and sirtuins: targets for new pharmacological interventions in human diseases. Pharmacol Res (2010) 0.76
Switch NFix developmental myogenesis. Dev Cell (2010) 0.75
Epigenetic control of reprogramming and cellular differentiation. Comp Funct Genomics (2012) 0.75