Roles of the major apoptotic nuclease-DNA fragmentation factor-in biology and disease.

PubWeight™: 0.97‹?› | Rank: Top 15%

🔗 View Article (PMID 18810317)

Published in Cell Mol Life Sci on January 01, 2009

Authors

P Widlak1, W T Garrard

Author Affiliations

1: Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, 44-100, Gliwice, Poland.

Articles citing this

Multifunctionality of the linker histones: an emerging role for protein-protein interactions. Cell Res (2010) 1.15

Cellular and nuclear degradation during apoptosis. Curr Opin Cell Biol (2009) 0.96

Mitigation of radiation injury by selective stimulation of the LPA(2) receptor. Biochim Biophys Acta (2013) 0.90

Leukemogenic rearrangements at the mixed lineage leukemia gene (MLL)-multiple rather than a single mechanism. Front Cell Dev Biol (2015) 0.90

Chromatin collapse during caspase-dependent apoptotic cell death requires DNA fragmentation factor, 40-kDa subunit-/caspase-activated deoxyribonuclease-mediated 3'-OH single-strand DNA breaks. J Biol Chem (2013) 0.89

DNA from dead cancer cells induces TLR9-mediated invasion and inflammation in living cancer cells. Breast Cancer Res Treat (2013) 0.87

Parole terms for a killer: directing caspase3/CAD induced DNA strand breaks to coordinate changes in gene expression. Cell Cycle (2010) 0.87

The roles and acting mechanism of Caenorhabditis elegans DNase II genes in apoptotic dna degradation and development. PLoS One (2009) 0.85

Kainate-mediated excitotoxicity induces neuronal death in the rat spinal cord in vitro via a PARP-1 dependent cell death pathway (Parthanatos). Cell Mol Neurobiol (2010) 0.84

Molecular Mechanisms Underlying Cell Death in Spinal Networks in Relation to Locomotor Activity After Acute Injury in vitro. Front Cell Neurosci (2011) 0.84

Effects of aging on apoptosis gene expression in oral mucosal tissues. Apoptosis (2013) 0.83

MyD88 mediates the decision to die by apoptosis or necroptosis after UV irradiation. Innate Immun (2013) 0.79

Small DNA pieces in C. elegans are intermediates of DNA fragmentation during apoptosis. PLoS One (2010) 0.79

Next-generation sequencing of apoptotic DNA breakpoints reveals association with actively transcribed genes and gene translocations. PLoS One (2011) 0.77

Genes of the mitochondrial apoptotic pathway in Mytilus galloprovincialis. PLoS One (2013) 0.77

Molecular and cellular pathways associated with chromosome 1p deletions during colon carcinogenesis. Clin Exp Gastroenterol (2011) 0.77

Determination of the apoptotic index in osteosarcoma tissue and its relationship with patients prognosis. Cancer Cell Int (2013) 0.76

Autonomous and non-autonomous roles of DNase II during cell death in C. elegans embryos. Biosci Rep (2015) 0.75

Compound A398, a novel podophyllotoxin analogue: cytotoxicity and induction of apoptosis in human leukemia cells. PLoS One (2014) 0.75

The Complete Genome Sequence of a Second Distinct Betabaculovirus from the True Armyworm, Mythimna unipuncta. PLoS One (2017) 0.75

Executioner caspases and CAD are essential for mutagenesis induced by TRAIL or vincristine. Cell Death Dis (2017) 0.75

Articles by these authors

Nuclease hypersensitive sites in chromatin. Annu Rev Biochem (1988) 13.48

Chromosomal loop anchorage of the kappa immunoglobulin gene occurs next to the enhancer in a region containing topoisomerase II sites. Cell (1986) 6.16

The ubiquitous potential Z-forming sequence of eucaryotes, (dT-dG)n . (dC-dA)n, is not detectable in the genomes of eubacteria, archaebacteria, or mitochondria. Mol Cell Biol (1986) 3.00

Chromatin structure of the potential Z-forming sequence (dT-dG)n X (dC-dA)n. Evidence for an "alternating-B" conformation. J Mol Biol (1985) 2.58

The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis. Proc Natl Acad Sci U S A (1998) 2.38

Partial purification of the template-active fraction of chromatin: a preliminary report. Proc Natl Acad Sci U S A (1974) 2.25

The enhancer of the immunoglobulin heavy chain locus is flanked by presumptive chromosomal loop anchorage elements. J Biol Chem (1987) 2.15

Differentiation-dependent chromatin alterations precede and accompany transcription of immunoglobulin light chain genes. J Biol Chem (1984) 1.99

Transcription-induced nucleosome 'splitting': an underlying structure for DNase I sensitive chromatin. EMBO J (1991) 1.93

Dysfunction of chromosomal loop attachment sites: illegitimate recombination linked to matrix association regions and topoisomerase II. Proc Natl Acad Sci U S A (1989) 1.91

Points of contact between histone H1 and the histone octamer. Proc Natl Acad Sci U S A (1980) 1.74

Subunit structures of different electrophoretic forms of nucleosomes. J Biol Chem (1980) 1.61

Action of recombinant human apoptotic endonuclease G on naked DNA and chromatin substrates: cooperation with exonuclease and DNase I. J Biol Chem (2001) 1.53

Two-dimensional electrophoretic analysis of polynucleosomes. J Biol Chem (1977) 1.50

Sharp boundaries demarcate the chromatin structure of a yeast heat-shock gene. J Mol Biol (1987) 1.47

Reassociation of histone H1 with nucleosomes. J Biol Chem (1979) 1.44

Nitrate reductase and soluble cytochrome c in Spirillum itersonii. J Bacteriol (1970) 1.38

Chromosomal loop anchorage sites appear to be evolutionarily conserved. FEBS Lett (1986) 1.38

Basal-level expression of the yeast HSP82 gene requires a heat shock regulatory element. Mol Cell Biol (1989) 1.33

5-methylcytosine is localized in nucleosomes that contain histone H1. Proc Natl Acad Sci U S A (1983) 1.32

Cleavage preferences of the apoptotic endonuclease DFF40 (caspase-activated DNase or nuclease) on naked DNA and chromatin substrates. J Biol Chem (2000) 1.32

Transcription termination and chromatin structure of the active immunoglobulin kappa gene locus. J Biol Chem (1986) 1.27

Positive DNA supercoiling generates a chromatin conformation characteristic of highly active genes. Proc Natl Acad Sci U S A (1991) 1.24

Varigated chromatin structures of mouse ribosomal RNA genes. J Mol Biol (1983) 1.24

Functional organization of the mammalian genome. Cold Spring Harb Symp Quant Biol (1974) 1.20

DNA supercoiling in chromatin structure and gene expression. Crit Rev Eukaryot Gene Expr (1992) 1.19

Immunoglobulin kappa gene expression after stable integration. I. Role of the intronic MAR and enhancer in plasmacytoma cells. J Biol Chem (1989) 1.18

Immunoglobulin kappa gene expression after stable integration. II. Role of the intronic MAR and enhancer in transgenic mice. J Biol Chem (1989) 1.16

Uncoupling gene activity from chromatin structure: promoter mutations can inactivate transcription of the yeast HSP82 gene without eliminating nucleosome-free regions. Proc Natl Acad Sci U S A (1992) 1.13

Histone molar ratios among different electrophoretic forms of mono- and dinucleosomes. J Biol Chem (1979) 1.13

Electrophoretic analyses of nucleosomes and other protein-DNA complexes. Methods Enzymol (1989) 1.11

Synthesis, assembly, and localization of periplasmic cytochrome c. J Biol Chem (1972) 1.09

Selective release of proteins from Spirillum itersonii by tris (hydroxymethyl) aminomethane and ethylenediaminetetraacetate. J Bacteriol (1971) 1.08

Overall pathway of mononucleosome production. J Biol Chem (1979) 1.08

Purification and properties of a neutral protease from rat liver chromatin. Biochemistry (1974) 1.07

Identification within the simian virus 40 genome of a chromosomal loop attachment site that contains topoisomerase II cleavage sites. J Virol (1990) 1.07

Stoichiometry of chromatin proteins. Biochem Biophys Res Commun (1974) 1.06

Vacuum blotting: a simple method for transferring DNA from sequencing gels to nylon membranes. Gene (1988) 1.06

Regulation of the human apoptotic DNase/RNase endonuclease G: involvement of Hsp70 and ATP. Apoptosis (2005) 1.04

Protein:DNA interactions at chromosomal loop attachment sites. Genome (1989) 1.04

Amino acid sequence of the N-terminal domain of calf thymus histone H2A.Z. FEBS Lett (1983) 1.02

Nonheme iron proteins. IV. Structural studies of Micrococcus aerogenes rubredoxin. Biochemistry (1968) 1.02

The active immunoglobulin kappa chain gene is packaged by non-ubiquitin-conjugated nucleosomes. Proc Natl Acad Sci U S A (1986) 1.01

RNA polymerase-specific nucleosome disruption by transcription in vivo. J Biol Chem (1999) 0.95

Ionic and cofactor requirements for the activity of the apoptotic endonuclease DFF40/CAD. Mol Cell Biochem (2001) 0.93

Changes in chromatin proteins during liver regeneration. J Biol Chem (1974) 0.93

Yeast calmodulin and a conserved nuclear protein participate in the in vivo binding of a matrix association region. Proc Natl Acad Sci U S A (1993) 0.93

Immunoglobulin kappa gene enhancers synergistically activate gene expression but independently determine chromatin structure. J Biol Chem (1992) 0.91

MARs of antigen receptor and co-receptor genes. Crit Rev Eukaryot Gene Expr (1999) 0.91

Evidence that the Igkappa gene MAR regulates the probability of premature V-J joining and somatic hypermutation. J Immunol (1999) 0.90

Heterogeneity in nucleosome spacing. J Biol Chem (1977) 0.90

In vitro chromatin assembly of the HIV-1 promoter. ATP-dependent polar repositioning of nucleosomes by Sp1 and NFkappaB. J Biol Chem (1997) 0.89

Template topology and transcription: chromatin templates relaxed by localized linearization are transcriptionally active in yeast. Mol Cell Biol (1997) 0.87

A targeted kappa immunoglobulin gene containing a deletion of the nuclear matrix association region exhibits spontaneous hyper-recombination in pre-B cells. Mol Immunol (1998) 0.86

Two forms of rat liver histone H3. FEBS Lett (1976) 0.85

High-level rearrangement and transcription of yeast artificial chromosome-based mouse Ig kappa transgenes containing distal regions of the contig. J Immunol (2000) 0.85

Transferring DNA from electrophoretically resolved nucleosomes to diazobenzyloxymethyl cellulose: properties of nucleosomes along mouse satellite DNA. Nucleic Acids Res (1982) 0.84

A method for mapping the distributions of modified and variant histones among mono- and polynucleosomes. J Biol Chem (1978) 0.83

A nonamer of histones in chromatin. J Biol Chem (1980) 0.82

Nucleosome arrangement with regard to DNA base composition. J Biol Chem (1979) 0.82

Biology of the histones. Life Sci (1974) 0.81

A method for genome comparisons and hybridization studies using known megabase-scale DNA sequences as a reference. Genomics (1997) 0.80

Preparation of chromatin from animal tissues and cultured cells. Methods Cell Biol (1978) 0.80

Temperature-dependent cleavage of chromatin by micrococcal nuclease near the nucleosome center. FEBS Lett (1986) 0.80

Yeast artificial chromosome contigs reveal that distal variable-region genes reside at least 3 megabases from the joining regions in the murine immunoglobulin kappa locus. Proc Natl Acad Sci U S A (1995) 0.78

Mutations that affect nuclear organization in yeast. Methods Cell Biol (1991) 0.78

Nucleotide sequence of the intron of the germline human kappa immunoglobulin gene connecting the J and C regions reveals a matrix association region (MAR) next to the enhancer. Nucleic Acids Res (1992) 0.78

Histone H3 disulfide reactions in interphase, mitotic, and native chromatin. J Biol Chem (1977) 0.78

Nucleosomes and regulation of gene expression. Structure of the HIV-1 5'LTR. Acta Biochim Pol (1998) 0.76

Accurate quantification of expression of transgenes marked with restriction endonuclease site polymorphisms by RT-PCR. Biotechniques (1998) 0.75

Histone phosphorylation during liver regeneration. Biochem Biophys Res Commun (1976) 0.75

Targeted linearization of DNA in vivo. Methods (1999) 0.75