Published in Glia on April 01, 2009
Layer-specific variation of iron content in cerebral cortex as a source of MRI contrast. Proc Natl Acad Sci U S A (2010) 2.33
Alzheimer's disease as homeostatic responses to age-related myelin breakdown. Neurobiol Aging (2009) 2.14
Tracking iron in multiple sclerosis: a combined imaging and histopathological study at 7 Tesla. Brain (2011) 1.68
Iron and neurodegeneration in the multiple sclerosis brain. Ann Neurol (2013) 1.43
Neurodevelopment in Early Childhood Affected by Prenatal Lead Exposure and Iron Intake. Medicine (Baltimore) (2016) 1.43
Brain structure in healthy adults is related to serum transferrin and the H63D polymorphism in the HFE gene. Proc Natl Acad Sci U S A (2012) 1.24
Genetics and Pathophysiology of Neurodegeneration with Brain Iron Accumulation (NBIA). Curr Neuropharmacol (2013) 1.20
Pathogenic implications of iron accumulation in multiple sclerosis. J Neurochem (2011) 1.16
Widespread age-related differences in the human brain microstructure revealed by quantitative magnetic resonance imaging. Neurobiol Aging (2014) 1.15
Glial development: the crossroads of regeneration and repair in the CNS. Neuron (2014) 1.12
Characterization of T(2)* heterogeneity in human brain white matter. Magn Reson Med (2009) 1.10
Iron deficiency in infancy is associated with altered neural correlates of recognition memory at 10 years. J Pediatr (2012) 1.10
Opiate drug use and the pathophysiology of neuroAIDS. Curr HIV Res (2012) 1.07
Glial dysfunction in the pathogenesis of α-synucleinopathies: emerging concepts. Acta Neuropathol (2011) 1.06
Friedreich's ataxia causes redistribution of iron, copper, and zinc in the dentate nucleus. Cerebellum (2012) 1.00
Mechanisms of brain iron transport: insight into neurodegeneration and CNS disorders. Future Med Chem (2010) 0.98
Post-acute pathological changes in the thalamus and internal capsule in aged mice following controlled cortical impact injury: a magnetic resonance imaging, iron histochemical, and glial immunohistochemical study. Neurosci Lett (2009) 0.97
Interactions of iron, dopamine and neuromelanin pathways in brain aging and Parkinson's disease. Prog Neurobiol (2015) 0.97
Ferritin stimulates oligodendrocyte genesis in the adult spinal cord and can be transferred from macrophages to NG2 cells in vivo. J Neurosci (2012) 0.94
Age-related differences in iron content of subcortical nuclei observed in vivo: a meta-analysis. Neuroimage (2012) 0.93
Sleep and neurofunctions throughout child development: lasting effects of early iron deficiency. J Pediatr Gastroenterol Nutr (2009) 0.93
Mapping brain metals to evaluate therapies for neurodegenerative disease. CNS Neurosci Ther (2010) 0.91
Adequacy of maternal iron status protects against behavioral, neuroanatomical, and growth deficits in fetal alcohol spectrum disorders. PLoS One (2012) 0.91
Ferroportin and exocytoplasmic ferroxidase activity are required for brain microvascular endothelial cell iron efflux. J Biol Chem (2013) 0.90
Restless legs syndrome presenting as an acute exacerbation of multiple sclerosis. Mult Scler Int (2011) 0.90
Visualizing iron in multiple sclerosis. Magn Reson Imaging (2013) 0.89
Postmortem and imaging based analyses reveal CNS decreased myelination in restless legs syndrome. Sleep Med (2011) 0.88
Prevalent iron metabolism gene variants associated with increased brain ferritin iron in healthy older men. J Alzheimers Dis (2010) 0.86
Striatal iron content predicts its shrinkage and changes in verbal working memory after two years in healthy adults. J Neurosci (2015) 0.86
Sleep alterations and iron deficiency anemia in infancy. Sleep Med (2010) 0.86
Iron deficiency alters expression of dopamine-related genes in the ventral midbrain in mice. Neuroscience (2013) 0.85
The effect of glia-glia interactions on oligodendrocyte precursor cell biology during development and in demyelinating diseases. Front Cell Neurosci (2013) 0.85
Iron chelation and multiple sclerosis. ASN Neuro (2014) 0.84
Serum exosomes in pregnancy-associated immune modulation and neuroprotection during CNS autoimmunity. Clin Immunol (2013) 0.84
PKA modulates iron trafficking in the striatum via small GTPase, Rhes. Neuroscience (2013) 0.84
Gestational nicotine exposure modifies myelin gene expression in the brains of adolescent rats with sex differences. Transl Psychiatry (2013) 0.83
Iron transport across the blood-brain barrier: development, neurovascular regulation and cerebral amyloid angiopathy. Cell Mol Life Sci (2014) 0.82
Abnormal brain iron metabolism in Irp2 deficient mice is associated with mild neurological and behavioral impairments. PLoS One (2014) 0.82
Comparison of histological techniques to visualize iron in paraffin-embedded brain tissue of patients with Alzheimer's disease. J Histochem Cytochem (2013) 0.82
Specific white matter tissue microstructure changes associated with obesity. Neuroimage (2015) 0.82
Pooled analysis of iron-related genes in Parkinson's disease: association with transferrin. Neurobiol Dis (2013) 0.81
Appraising the Role of Iron in Brain Aging and Cognition: Promises and Limitations of MRI Methods. Neuropsychol Rev (2015) 0.81
A role for hemopexin in oligodendrocyte differentiation and myelin formation. PLoS One (2011) 0.81
Multiple sclerosis: molecular mechanisms and therapeutic opportunities. Antioxid Redox Signal (2013) 0.80
Polymorphisms in the genes coding for iron binding and transporting proteins are associated with disability, severity, and early progression in multiple sclerosis. BMC Med Genet (2012) 0.80
Transferrin receptor and ferritin-H are developmentally regulated in oligodendrocyte lineage cells. Neural Regen Res (2013) 0.80
Assessment of iron deposition and white matter maturation in infant brains by using enhanced T2 star weighted angiography (ESWAN): R2* versus phase values. PLoS One (2014) 0.80
Neuroimaging, nutrition, and iron-related genes. Cell Mol Life Sci (2013) 0.80
Deficiency of Calcium-Independent Phospholipase A2 Beta Induces Brain Iron Accumulation through Upregulation of Divalent Metal Transporter 1. PLoS One (2015) 0.80
Structure predicts function: combining non-invasive electrophysiology with in-vivo histology. Neuroimage (2014) 0.80
Changes in NG2 cells and oligodendrocytes in a new model of intraspinal hemorrhage. Exp Neurol (2014) 0.79
Divalent metal transporter 1 (DMT1) in the brain: implications for a role in iron transport at the blood-brain barrier, and neuronal and glial pathology. Front Mol Neurosci (2015) 0.79
Brain iron accumulation affects myelin-related molecular systems implicated in a rare neurogenetic disease family with neuropsychiatric features. Mol Psychiatry (2016) 0.79
Premenopausal hysterectomy is associated with increased brain ferritin iron. Neurobiol Aging (2011) 0.79
Impaired myelination and reduced brain ferric iron in the mouse model of mucolipidosis IV. Dis Model Mech (2015) 0.79
Mechanisms and regulation of iron trafficking across the capillary endothelial cells of the blood-brain barrier. Front Mol Neurosci (2015) 0.78
Prenatal exposure to multiple pesticides is associated with auditory brainstem response at 9months in a cohort study of Chinese infants. Environ Int (2016) 0.78
Astrocytes in Oligodendrocyte Lineage Development and White Matter Pathology. Front Cell Neurosci (2016) 0.78
The therapeutic effects of MSc1 nanocomplex, synthesized by nanochelating technology, on experimental autoimmune encephalomyelitic C57/BL6 mice. Int J Nanomedicine (2014) 0.78
Enhanced Histochemical Detection of Iron in Paraffin Sections of Mouse Central Nervous System Tissue: Application in the APP/PS1 Mouse Model of Alzheimer's Disease. ASN Neuro (2016) 0.77
Identifying the threshold of iron deficiency in the central nervous system of the rat by the auditory brainstem response. ASN Neuro (2015) 0.77
Effect modification by transferrin C2 polymorphism on lead exposure, hemoglobin levels, and IQ. Neurotoxicology (2013) 0.77
Persistent 7-tesla phase rim predicts poor outcome in new multiple sclerosis patient lesions. J Clin Invest (2016) 0.77
Iron Level and Myelin Content in the Ventral Striatum Predict Memory Performance in the Aging Brain. J Neurosci (2016) 0.77
In vivo evidence of neurophysiological maturation of the human adolescent striatum. Dev Cogn Neurosci (2014) 0.77
Alpha-synuclein and iron: two keys unlocking Parkinson's disease. J Neural Transm (Vienna) (2017) 0.76
The conundrum of iron in multiple sclerosis--time for an individualised approach. Metab Brain Dis (2012) 0.76
Relationship between iron accumulation and white matter injury in multiple sclerosis: a case-control study. J Neurol (2014) 0.76
Oligodendroglia and Myelin in Neurodegenerative Diseases: More Than Just Bystanders? Mol Neurobiol (2015) 0.76
Postnatal Iron Deficiency Alters Brain Development in Piglets. J Nutr (2016) 0.76
Is it time to rethink cord management when resuscitation is needed? J Midwifery Womens Health (2014) 0.76
Impact of neonatal iron deficiency on hippocampal DNA methylation and gene transcription in a porcine biomedical model of cognitive development. BMC Genomics (2016) 0.75
Histological Basis of Laminar MRI Patterns in High Resolution Images of Fixed Human Auditory Cortex. Front Neurosci (2016) 0.75
Prenatal Iron Deficiency and Auditory Brainstem Responses at 3 and 10 Months: A Pilot Study. Hong Kong J Paediatr (2015) 0.75
New Insights into the Crosstalk between NMDARs and Iron: Implications for Understanding Pathology of Neurological Diseases. Front Mol Neurosci (2017) 0.75
Na(+)/H(+) Exchanger 9 Regulates Iron Mobilization at the Blood-Brain Barrier in Response to Iron Starvation. J Biol Chem (2017) 0.75
Transferrin Receptor Controls AMPA Receptor Trafficking Efficiency and Synaptic Plasticity. Sci Rep (2016) 0.75
Insula and somatosensory cortical myelination and iron markers underlie individual differences in empathy. Sci Rep (2017) 0.75
A Systematic Relationship Between Functional Connectivity and Intracortical Myelin in the Human Cerebral Cortex. Cereb Cortex (2017) 0.75
Iron homeostasis in peripheral nervous system, still a black box? Antioxid Redox Signal (2014) 0.75
Accelerated neuronal differentiation toward motor neuron lineage from human embryonic stem cell line (H9). Tissue Eng Part C Methods (2014) 0.75
Providing male rats deficient in iron and n-3 fatty acids with iron and alpha-linolenic acid alone affects brain serotonin and cognition differently from combined provision. Lipids Health Dis (2014) 0.75
Reduced white matter MRI transverse relaxation rate in cognitively normal H63D-HFE human carriers and H67D-HFE mice. Brain Imaging Behav (2016) 0.75
Food Insecurity, Poor Diet Quality, and Suboptimal Intakes of Folate and Iron Are Independently Associated with Perceived Mental Health in Canadian Adults. Nutrients (2017) 0.75
Semaphorin4A Is Cytotoxic to Oligodendrocytes and Is Elevated in Microglia and Multiple Sclerosis. ASN Neuro (2015) 0.75
Restless legs syndrome as the initial presentation of multiple sclerosis. Case Rep Med (2013) 0.75
The Relationship Between Iron Deficiency Anemia and Sensorineural Hearing Loss in the Pediatric and Adolescent Population. Am J Audiol (2017) 0.75
Inversion recovery ultrashort echo time magnetic resonance imaging: A method for simultaneous direct detection of myelin and high signal demonstration of iron deposition in the brain - A feasibility study. Magn Reson Imaging (2016) 0.75
[Computational neuroanatomy and microstructure imaging using magnetic resonance imaging]. Nervenarzt (2017) 0.75
Iron, brain ageing and neurodegenerative disorders. Nat Rev Neurosci (2004) 5.37
Iron status and neural functioning. Annu Rev Nutr (2003) 2.63
A diet-induced mouse model for glutaric aciduria type I. Brain (2006) 2.31
Persistent neurochemical and behavioral abnormalities in adulthood despite early iron supplementation for perinatal iron deficiency anemia in rats. Behav Brain Res (2006) 2.02
Hypoxia-inducible factor prolyl 4-hydroxylase inhibition. A target for neuroprotection in the central nervous system. J Biol Chem (2005) 1.95
Staufen recruitment into stress granules does not affect early mRNA transport in oligodendrocytes. Mol Biol Cell (2004) 1.82
Ferritin subunits in CSF are decreased in restless legs syndrome. J Lab Clin Med (2006) 1.67
Pre- and postweaning iron deficiency alters myelination in Sprague-Dawley rats. Dev Neurosci (2003) 1.51
Moderate iron deficiency in infancy: biology and behavior in young rats. Behav Brain Res (2006) 1.43
Detection of cancer cells in the cerebrospinal fluid: current methods and future directions. Fluids Barriers CNS (2011) 1.32
Age-dependent retinal iron accumulation and degeneration in hepcidin knockout mice. Invest Ophthalmol Vis Sci (2011) 1.32
Iron, the substantia nigra and related neurological disorders. Biochim Biophys Acta (2008) 1.24
Brain iron uptake and homeostatic mechanisms: an overview. Biometals (2003) 1.21
MRI and histological analysis of beta-amyloid plaques in both human Alzheimer's disease and APP/PS1 transgenic mice. J Magn Reson Imaging (2009) 1.18
Developmental changes in the expression of iron regulatory proteins and iron transport proteins in the perinatal rat brain. J Neurosci Res (2002) 1.18
The significance of ferritin in cancer: anti-oxidation, inflammation and tumorigenesis. Biochim Biophys Acta (2013) 1.17
Iron deficiency alters iron regulatory protein and iron transport protein expression in the perinatal rat brain. Pediatr Res (2003) 1.15
Perinatal nutritional iron deficiency permanently impairs hippocampus-dependent trace fear conditioning in rats. Nutr Neurosci (2005) 1.12
Regulation, mechanisms and proposed function of ferritin translocation to cell nuclei. J Cell Sci (2002) 1.10
Plasma biomarkers associated with ALS and their relationship to iron homeostasis. Muscle Nerve (2010) 1.09
Interleukin-13 receptor-targeted nanovesicles are a potential therapy for glioblastoma multiforme. Mol Cancer Ther (2006) 1.08
Ferritin stimulates breast cancer cells through an iron-independent mechanism and is localized within tumor-associated macrophages. Breast Cancer Res Treat (2013) 1.07
Mechanism of age-dependent susceptibility and novel treatment strategy in glutaric acidemia type I. J Clin Invest (2007) 1.07
Tim-2 is the receptor for H-ferritin on oligodendrocytes. J Neurochem (2008) 1.06
Efficacy of interleukin-13 receptor-targeted liposomal doxorubicin in the intracranial brain tumor model. Mol Cancer Ther (2009) 1.04
Genetic heterogeneity of amyotrophic lateral sclerosis: implications for clinical practice and research. Muscle Nerve (2014) 1.03
Gene expression of transferrin and transferrin receptor in brains of control vs. iron-deficient rats. Nutr Neurosci (2003) 1.02
HFE gene variants affect iron in the brain. J Nutr (2011) 1.00
Behavior and monoamine deficits in prenatal and perinatal iron deficiency are not corrected by early postnatal moderate-iron or high-iron diets in rats. J Nutr (2012) 0.99
The multiple roles of myelin protein genes during the development of the oligodendrocyte. ASN Neuro (2010) 0.97
Direct magnetic resonance imaging of histological tissue samples at 3.0T. Magn Reson Med (2007) 0.97
Mitochondrial ferritin in the substantia nigra in restless legs syndrome. J Neuropathol Exp Neurol (2009) 0.97
Is ferroportin-hepcidin signaling altered in restless legs syndrome? J Neurol Sci (2006) 0.97
Nuclear ferritin: A new role for ferritin in cell biology. Biochim Biophys Acta (2010) 0.96
H-ferritin is the major source of iron for oligodendrocytes. Glia (2011) 0.96
The dopaminergic neurons of the A11 system in RLS autopsy brains appear normal. Sleep Med (2009) 0.96
Functional roles of transferrin in the brain. Biochim Biophys Acta (2011) 0.96
Gender and iron genes may modify associations between brain iron and memory in healthy aging. Neuropsychopharmacology (2011) 0.96
Mutant HFE H63D protein is associated with prolonged endoplasmic reticulum stress and increased neuronal vulnerability. J Biol Chem (2011) 0.95
Consequences of expressing mutants of the hemochromatosis gene (HFE) into a human neuronal cell line lacking endogenous HFE. FASEB J (2006) 0.95
Olfactory deficit detected by fMRI in early Alzheimer's disease. Brain Res (2010) 0.95
Classical 18.5-and 21.5-kDa isoforms of myelin basic protein inhibit calcium influx into oligodendroglial cells, in contrast to golli isoforms. J Neurosci Res (2011) 0.95
Characterization of nuclear ferritin and mechanism of translocation. Biochem J (2005) 0.95
Apotransferrin promotes the differentiation of two oligodendroglial cell lines. Glia (2004) 0.94
Cytokine toxicity to oligodendrocyte precursors is mediated by iron. Glia (2005) 0.93
Myelination and motor coordination are increased in transferrin transgenic mice. J Neurosci Res (2003) 0.92
Ferritin levels in the cerebrospinal fluid and restless legs syndrome: effects of different clinical phenotypes. Sleep (2005) 0.92
STAT3-mediated astrogliosis protects myelin development in neonatal brain injury. Ann Neurol (2012) 0.91
Abnormally increased CSF 3-Ortho-methyldopa (3-OMD) in untreated restless legs syndrome (RLS) patients indicates more severe disease and possibly abnormally increased dopamine synthesis. Sleep Med (2008) 0.91
Brain iron uptake in hypotransferrinemic mice: influence of systemic iron status. J Neurosci Res (2004) 0.91
Differential expression of genes in amyotrophic lateral sclerosis revealed by profiling the post mortem cortex. Amyotroph Lateral Scler (2006) 0.91
Regulation of the profile of iron-management proteins in brain microvasculature. J Cereb Blood Flow Metab (2004) 0.90
Heavy chain ferritin siRNA delivered by cationic liposomes increases sensitivity of cancer cells to chemotherapeutic agents. Cancer Res (2011) 0.90
Regulation of L-type Ca++ currents and process morphology in white matter oligodendrocyte precursor cells by golli-myelin proteins. Glia (2010) 0.89
Proline substitutions and threonine pseudophosphorylation of the SH3 ligand of 18.5-kDa myelin basic protein decrease its affinity for the Fyn-SH3 domain and alter process development and protein localization in oligodendrocytes. J Neurosci Res (2011) 0.89
Influence of HFE variants and cellular iron on monocyte chemoattractant protein-1. J Neuroinflammation (2009) 0.89
Interactions and reactions of ferritin with DNA. J Biol Chem (2004) 0.89
Redox metals in Alzheimer's disease. Ann N Y Acad Sci (2004) 0.88
Prevalent iron metabolism gene variants associated with increased brain ferritin iron in healthy older men. J Alzheimers Dis (2010) 0.86
Quantitative proteomic analyses of cerebrospinal fluid using iTRAQ in a primate model of iron deficiency anemia. Dev Neurosci (2012) 0.86
HFE polymorphisms influence the response to chemotherapeutic agents via induction of p16INK4A. Int J Cancer (2011) 0.86
The mechanism of vanadium-mediated developmental hypomyelination is related to destruction of oligodendrocyte progenitors through a relationship with ferritin and iron. Neurotox Res (2010) 0.86
Alteration of iron regulatory proteins (IRP1 and IRP2) and ferritin in the brains of scrapie-infected mice. Neurosci Lett (2007) 0.85
Subcellular localization of iron regulatory proteins to Golgi and ER membranes. J Cell Sci (2005) 0.85
A mutation in the HFE gene is associated with altered brain iron profiles and increased oxidative stress in mice. Biochim Biophys Acta (2013) 0.84
CSF proteomic analysis reveals persistent iron deficiency-induced alterations in non-human primate infants. J Neurochem (2007) 0.84
Metabolic analysis of mouse brains that have compromised iron storage. Metab Brain Dis (2006) 0.83
H and L ferritin subunit mRNA expression differs in brains of control and iron-deficient rats. J Nutr (2002) 0.82
Increased cellular iron levels affect matrix metalloproteinase expression and phagocytosis in activated microglia. Neurosci Lett (2011) 0.82
Inhibition of the proteasome by lactacystin enhances oligodendroglial cell differentiation. J Neurosci (2003) 0.82
Gene-environment interactions: neurodegeneration in non-mammals and mammals. Neurotoxicology (2010) 0.81
The lipophilic iron compound TMH-ferrocene [(3,5,5-trimethylhexanoyl)ferrocene] increases iron concentrations, neuronal L-ferritin, and heme oxygenase in brains of BALB/c mice. Biol Trace Elem Res (2002) 0.81
Nitric oxide protects astrocytes from oxidative stress. Ann N Y Acad Sci (2002) 0.81
Adaptive endoplasmic reticulum stress alters cellular responses to the extracellular milieu. J Neurosci Res (2015) 0.80
HFE polymorphisms affect cellular glutamate regulation. Neurobiol Aging (2009) 0.80
Mechanism of metabolic stroke and spontaneous cerebral hemorrhage in glutaric aciduria type I. Acta Neuropathol Commun (2014) 0.80
The Deterioration Seen in Myelin Related Morphophysiology in Vanadium Exposed Rats is Partially Protected by Concurrent Iron Deficiency. Niger J Physiol Sci (2016) 0.79
Proteomic analysis of the cerebrospinal fluid of patients with restless legs syndrome/Willis-Ekbom disease. Fluids Barriers CNS (2013) 0.79
Apotransferrin decreases migration and enhances differentiation of oligodendroglial progenitor cells in an in vitro system. Dev Neurosci (2002) 0.79
Differential gene expression during development in two oligodendroglial cell lines overexpressing transferrin: a cDNA array analysis. Dev Neurosci (2007) 0.79
Overexpression of human transferrin in two oligodendroglial cell lines enhances their differentiation. Glia (2005) 0.79
Maturational and aging effects on human brain apparent transverse relaxation. PLoS One (2012) 0.79
Intranasal administration of aTf protects and repairs the neonatal white matter after a cerebral hypoxic-ischemic event. Glia (2012) 0.79
H63D HFE polymorphisms are associated with increased disease duration and decreased muscle superoxide dismutase-1 expression in amyotrophic lateral sclerosis patients. Muscle Nerve (2013) 0.78
Young coconut juice, a potential therapeutic agent that could significantly reduce some pathologies associated with Alzheimer's disease: novel findings. Br J Nutr (2010) 0.78
The impact of host iron homeostasis on disease. Preface. Biochim Biophys Acta (2009) 0.78
Iron and ER stress in neurodegenerative disease. Biometals (2012) 0.78
The effect of iron in MRI and transverse relaxation of amyloid-beta plaques in Alzheimer's disease. NMR Biomed (2014) 0.78
Development of a fluorescent reporter to assess iron regulatory protein activity in living cells. Biochim Biophys Acta (2004) 0.78
Upregulation of iron regulatory proteins and divalent metal transporter-1 isoforms in the rat hippocampus after kainate induced neuronal injury. Exp Brain Res (2005) 0.78
HFE polymorphisms affect survival of brain tumor patients. J Neurooncol (2014) 0.78
Serum ferritin is elevated in amyotrophic lateral sclerosis patients. Amyotroph Lateral Scler Frontotemporal Degener (2014) 0.78
Abnormal iron delivery to the bone marrow in neonatal hypotransferrinemic mice. Biometals (2002) 0.78
Histological-MRI correlation in the primary motor cortex of patients with amyotrophic lateral sclerosis. J Magn Reson Imaging (2014) 0.77
Morphological changes of myelin sheaths in rats intracranially injected with apotransferrin. Neurochem Res (2003) 0.77
Expression of the HFE allelic variant H63D in SH-SY5Y cells affects tau phosphorylation at serine residues. Neurobiol Aging (2009) 0.77