Published in J Virol on October 08, 2008
Nuclear IFI16 induction of IRF-3 signaling during herpesviral infection and degradation of IFI16 by the viral ICP0 protein. Proc Natl Acad Sci U S A (2012) 2.14
A viral E3 ligase targets RNF8 and RNF168 to control histone ubiquitination and DNA damage responses. EMBO J (2010) 1.75
Regulation of ICP0-null mutant herpes simplex virus type 1 infection by ND10 components ATRX and hDaxx. J Virol (2010) 1.73
Transcription of the herpes simplex virus latency-associated transcript promotes the formation of facultative heterochromatin on lytic promoters. J Virol (2009) 1.65
Analysis of the functions of herpes simplex virus type 1 regulatory protein ICP0 that are critical for lytic infection and derepression of quiescent viral genomes. J Virol (2009) 1.48
Herpes simplex virus 1 infection induces activation and subsequent inhibition of the IFI16 and NLRP3 inflammasomes. J Virol (2013) 1.46
Cooperative assembly of IFI16 filaments on dsDNA provides insights into host defense strategy. Proc Natl Acad Sci U S A (2013) 1.43
The differential mobilization of histones H3.1 and H3.3 by herpes simplex virus 1 relates histone dynamics to the assembly of viral chromatin. PLoS Pathog (2013) 1.42
Snapshots: chromatin control of viral infection. Virology (2013) 1.39
Nuclear interferon-inducible protein 16 promotes silencing of herpesviral and transfected DNA. Proc Natl Acad Sci U S A (2013) 1.31
Herpes simplex virus immediate-early ICP0 protein inhibits Toll-like receptor 2-dependent inflammatory responses and NF-kappaB signaling. J Virol (2010) 1.23
The checkpoints of viral gene expression in productive and latent infection: the role of the HDAC/CoREST/LSD1/REST repressor complex. J Virol (2011) 1.20
Human cytomegalovirus persistence. Cell Microbiol (2012) 1.16
IFI16 restricts HSV-1 replication by accumulating on the hsv-1 genome, repressing HSV-1 gene expression, and directly or indirectly modulating histone modifications. PLoS Pathog (2014) 1.15
Transcriptional coactivator HCF-1 couples the histone chaperone Asf1b to HSV-1 DNA replication components. Proc Natl Acad Sci U S A (2010) 1.13
A neuron-specific host microRNA targets herpes simplex virus-1 ICP0 expression and promotes latency. Cell Host Microbe (2014) 1.11
During lytic infections, herpes simplex virus type 1 DNA is in complexes with the properties of unstable nucleosomes. J Virol (2009) 1.08
Towards an understanding of the herpes simplex virus type 1 latency-reactivation cycle. Interdiscip Perspect Infect Dis (2010) 1.05
Cellular sensing of viral DNA and viral evasion mechanisms. Annu Rev Microbiol (2014) 1.05
Activities of ICP0 involved in the reversal of silencing of quiescent herpes simplex virus 1. J Virol (2011) 1.05
Entry of herpes simplex virus type 1 (HSV-1) into the distal axons of trigeminal neurons favors the onset of nonproductive, silent infection. PLoS Pathog (2012) 1.02
HSV-1-induced SOCS-1 expression in keratinocytes: use of a SOCS-1 antagonist to block a novel mechanism of viral immune evasion. J Immunol (2009) 1.02
Single-cell analysis of Daxx and ATRX-dependent transcriptional repression. J Cell Sci (2012) 1.02
Regulation of the ORF61 promoter and ORF61 functions in varicella-zoster virus replication and pathogenesis. J Virol (2009) 1.01
Regulation of histone deposition on the herpes simplex virus type 1 genome during lytic infection. J Virol (2009) 1.00
Epigenetic histone modification of Epstein-Barr virus BZLF1 promoter during latency and reactivation in Raji cells. J Virol (2012) 0.99
A cultured affair: HSV latency and reactivation in neurons. Trends Microbiol (2012) 0.98
Recruitment of the transcriptional coactivator HCF-1 to viral immediate-early promoters during initiation of reactivation from latency of herpes simplex virus type 1. J Virol (2009) 0.98
Transcriptional coactivators are not required for herpes simplex virus type 1 immediate-early gene expression in vitro. J Virol (2009) 0.97
Epigenetic modulation of gene expression from quiescent herpes simplex virus genomes. J Virol (2009) 0.96
HSV-1 ICP0: An E3 Ubiquitin Ligase That Counteracts Host Intrinsic and Innate Immunity. Cells (2014) 0.96
Transcription of the herpes simplex virus 1 genome during productive and quiescent infection of neuronal and nonneuronal cells. J Virol (2014) 0.96
Herpes simplex virus VP16, but not ICP0, is required to reduce histone occupancy and enhance histone acetylation on viral genomes in U2OS osteosarcoma cells. J Virol (2009) 0.95
Reversal of heterochromatic silencing of quiescent herpes simplex virus type 1 by ICP0. J Virol (2010) 0.95
A targeted RNA interference screen reveals novel epigenetic factors that regulate herpesviral gene expression. MBio (2014) 0.95
The dynamics of HCF-1 modulation of herpes simplex virus chromatin during initiation of infection. Viruses (2013) 0.94
HSV-1 ICP0: paving the way for viral replication. Future Virol (2011) 0.94
ICP0 dismantles microtubule networks in herpes simplex virus-infected cells. PLoS One (2010) 0.93
Herpes simplex virus 1 DNA is in unstable nucleosomes throughout the lytic infection cycle, and the instability of the nucleosomes is independent of DNA replication. J Virol (2012) 0.93
Hyperphosphorylation of histone deacetylase 2 by alphaherpesvirus US3 kinases. J Virol (2010) 0.93
A comparison of herpes simplex virus type 1 and varicella-zoster virus latency and reactivation. J Gen Virol (2015) 0.93
Role of chromatin during herpesvirus infections. Biochim Biophys Acta (2009) 0.91
The early gene hhi1 reactivates Heliothis zea nudivirus 1 in latently infected cells. J Virol (2009) 0.91
Dynamic association of gammaherpesvirus DNA with core histone during de novo lytic infection of primary cells. Virology (2011) 0.88
Dynamic modulation of HSV chromatin drives initiation of infection and provides targets for epigenetic therapies. Virology (2015) 0.87
Chromatin dynamics during lytic infection with herpes simplex virus 1. Viruses (2013) 0.87
Cellular SNF2H chromatin-remodeling factor promotes herpes simplex virus 1 immediate-early gene expression and replication. MBio (2011) 0.87
Chromatin assembly on herpes simplex virus 1 DNA early during a lytic infection is Asf1a dependent. J Virol (2012) 0.86
ICP0 antagonizes ICP4-dependent silencing of the herpes simplex virus ICP0 gene. PLoS One (2010) 0.86
Role of herpes simplex virus ICP0 in the transactivation of genes introduced by infection or transfection: a reappraisal. J Virol (2010) 0.85
Nuclear sensing of viral DNA, epigenetic regulation of herpes simplex virus infection, and innate immunity. Virology (2015) 0.85
Proteome alterations in primary human alveolar macrophages in response to influenza A virus infection. J Proteome Res (2012) 0.85
Herpesviral ICP0 Protein Promotes Two Waves of Heterochromatin Removal on an Early Viral Promoter during Lytic Infection. MBio (2016) 0.85
Changes to euchromatin on LAT and ICP4 following reactivation are more prevalent in an efficiently reactivating strain of HSV-1. PLoS One (2010) 0.84
Simian TRIM5alpha proteins reduce replication of herpes simplex virus. Virology (2010) 0.84
Herpes simplex virus 1 ICP0 phosphorylation site mutants are attenuated for viral replication and impaired for explant-induced reactivation. J Virol (2011) 0.83
Nucleosome maps of the human cytomegalovirus genome reveal a temporal switch in chromatin organization linked to a major IE protein. Proc Natl Acad Sci U S A (2013) 0.83
Core histones H2B and H4 are mobilized during infection with herpes simplex virus 1. J Virol (2011) 0.83
Chromatin assembly on herpes simplex virus genomes during lytic infection. Biochim Biophys Acta (2009) 0.83
Genetic engineering of a modified herpes simplex virus 1 vaccine vector. Vaccine (2009) 0.83
Complementation of a herpes simplex virus ICP0 null mutant by varicella-zoster virus ORF61p. J Virol (2009) 0.83
Epigenetic repression of herpes simplex virus infection by the nucleosome remodeler CHD3. MBio (2014) 0.83
The alphaherpesvirus serine/threonine kinase us3 disrupts promyelocytic leukemia protein nuclear bodies. J Virol (2011) 0.81
A Herpesviral Lytic Protein Regulates the Structure of Latent Viral Chromatin. MBio (2016) 0.80
Production of immunogenic West Nile virus-like particles using a herpes simplex virus 1 recombinant vector. Virology (2016) 0.80
Barrier to auto integration factor becomes dephosphorylated during HSV-1 Infection and Can Act as a host defense by impairing viral DNA replication and gene expression. PLoS One (2014) 0.80
Identification of TRIM27 as a novel degradation target of herpes simplex virus 1 ICP0. J Virol (2014) 0.80
Roles of the nuclear lamina in stable nuclear association and assembly of a herpesviral transactivator complex on viral immediate-early genes. MBio (2012) 0.80
Bovine Herpes Virus 1 (BHV-1) and Herpes Simplex Virus Type 1 (HSV-1) Promote Survival of Latently Infected Sensory Neurons, in Part by Inhibiting Apoptosis. J Cell Death (2013) 0.79
Time-resolved Global and Chromatin Proteomics during Herpes Simplex Virus Type 1 (HSV-1) Infection. Mol Cell Proteomics (2017) 0.78
Genome wide nucleosome mapping for HSV-1 shows nucleosomes are deposited at preferred positions during lytic infection. PLoS One (2015) 0.78
Role of ND10 nuclear bodies in the chromatin repression of HSV-1. Virol J (2016) 0.78
Role of polycomb proteins in regulating HSV-1 latency. Viruses (2013) 0.77
Proteomic analysis of the herpes simplex virus 1 virion protein 16 transactivator protein in infected cells. Proteomics (2015) 0.77
Inhibition of O-Linked N-Acetylglucosamine Transferase Reduces Replication of Herpes Simplex Virus and Human Cytomegalovirus. J Virol (2015) 0.77
Herpes simplex virus and the lexicon of latency and reactivation: a call for defining terms and building an integrated collective framework. F1000Res (2016) 0.76
Chromatin Modulation of Herpesvirus Lytic Gene Expression: Managing Nucleosome Density and Heterochromatic Histone Modifications. MBio (2016) 0.76
Gene Expression Correlates with the Number of Herpes Viral Genomes Initiating Infection in Single Cells. PLoS Pathog (2016) 0.75
Two Populations of Viral Minichromosomes Are Present in a Geminivirus-Infected Plant Showing Symptom Remission (Recovery). J Virol (2016) 0.75
Quantitative Analysis of HSV Gene Expression during Lytic Infection. Curr Protoc Microbiol (2014) 0.75
Histone Deacetylase Inhibitors Reduce the Number of Herpes Simplex Virus-1 Genomes Initiating Expression in Individual Cells. Front Microbiol (2016) 0.75
Cellular Transcriptional Coactivator RanBP10 and Herpes Simplex Virus 1 ICP0 Interact and Synergistically Promote Viral Gene Expression and Replication. J Virol (2016) 0.75
An Essential Viral Transcription Activator Modulates Chromatin Dynamics. PLoS Pathog (2016) 0.75
The Telomerase Inhibitor MST-312 Interferes with Multiple Steps in the Herpes Simplex Virus Life Cycle. J Virol (2015) 0.75
Use of biotinylated plasmid DNA as a surrogate for HSV DNA to identify proteins that repress or activate viral gene expression. Proc Natl Acad Sci U S A (2012) 0.75
Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesis. Cell (2004) 10.16
Deciphering the transcriptional histone acetylation code for a human gene. Cell (2002) 8.96
Isolation and characterization of deletion mutants of herpes simplex virus type 1 in the gene encoding immediate-early regulatory protein ICP4. J Virol (1985) 8.12
Trans activation of transcription by herpes virus products: requirement for two HSV-1 immediate-early polypeptides for maximum activity. EMBO J (1984) 7.33
Function and selectivity of bromodomains in anchoring chromatin-modifying complexes to promoter nucleosomes. Cell (2002) 7.10
Isolation and characterization of a herpes simplex virus type 1 mutant containing a deletion within the gene encoding the immediate early polypeptide Vmw110. J Gen Virol (1986) 6.74
Stimulation of expression of a herpes simplex virus DNA-binding protein by two viral functions. Mol Cell Biol (1985) 5.76
Deletion mutants in the gene encoding the herpes simplex virus type 1 immediate-early protein ICP0 exhibit impaired growth in cell culture. J Virol (1987) 5.71
Three trans-acting regulatory proteins of herpes simplex virus modulate immediate-early gene expression in a pathway involving positive and negative feedback regulation. J Virol (1985) 5.63
Histones are first hyperacetylated and then lose contact with the activated PHO5 promoter. Mol Cell (2003) 5.41
Identification of immediate early genes from herpes simplex virus that transactivate the virus thymidine kinase gene. Proc Natl Acad Sci U S A (1985) 5.40
Transcriptional activators direct histone acetyltransferase complexes to nucleosomes. Nature (1998) 4.68
Alternative mechanisms for activation of human immunodeficiency virus enhancer in T cells. Science (1988) 4.16
Chromatin remodelling: the industrial revolution of DNA around histones. Nat Rev Mol Cell Biol (2006) 3.79
Herpes simplex virus type 1 ICP0 plays a critical role in the de novo synthesis of infectious virus following transfection of viral DNA. J Virol (1989) 3.63
Histone acetyltransferase complexes stabilize swi/snf binding to promoter nucleosomes. Cell (2001) 3.54
The ATRX syndrome protein forms a chromatin-remodeling complex with Daxx and localizes in promyelocytic leukemia nuclear bodies. Proc Natl Acad Sci U S A (2003) 3.52
During latency, herpes simplex virus type 1 DNA is associated with nucleosomes in a chromatin structure. J Virol (1989) 3.29
Stages in the nuclear association of the herpes simplex virus transcriptional activator protein ICP4. J Virol (1987) 3.24
Physical and functional domains of the herpes simplex virus transcriptional regulatory protein ICP4. J Virol (1988) 3.14
Formation of DNA replication structures in herpes virus-infected cells requires a viral DNA binding protein. Cell (1988) 3.13
Herpes simplex virus type 1 ICP0 regulates expression of immediate-early, early, and late genes in productively infected cells. J Virol (1992) 3.10
PML contributes to a cellular mechanism of repression of herpes simplex virus type 1 infection that is inactivated by ICP0. J Virol (2006) 3.03
Definition of a series of stages in the association of two herpesviral proteins with the cell nucleus. J Virol (1982) 2.99
Persistence and expression of the herpes simplex virus genome in the absence of immediate-early proteins. J Virol (1998) 2.97
Herpesviral latency-associated transcript gene promotes assembly of heterochromatin on viral lytic-gene promoters in latent infection. Proc Natl Acad Sci U S A (2005) 2.88
Chromatin control of herpes simplex virus lytic and latent infection. Nat Rev Microbiol (2008) 2.86
Herpes simplex virus type 1 immediate-early protein Vmw110 reactivates latent herpes simplex virus type 2 in an in vitro latency system. J Virol (1989) 2.76
Components of the REST/CoREST/histone deacetylase repressor complex are disrupted, modified, and translocated in HSV-1-infected cells. Proc Natl Acad Sci U S A (2005) 2.67
Activation domain-mediated targeting of the SWI/SNF complex to promoters stimulates transcription from nucleosome arrays. Mol Cell (1999) 2.63
Tandem bromodomains in the chromatin remodeler RSC recognize acetylated histone H3 Lys14. EMBO J (2004) 2.46
Herpes simplex virus-infected cell protein 0 blocks the silencing of viral DNA by dissociating histone deacetylases from the CoREST-REST complex. Proc Natl Acad Sci U S A (2007) 2.37
ND10 components relocate to sites associated with herpes simplex virus type 1 nucleoprotein complexes during virus infection. J Virol (2005) 2.36
Sequential recruitment of HAT and SWI/SNF components to condensed chromatin by VP16. Curr Biol (2003) 2.31
Intranuclear localization of herpes simplex virus immediate-early and delayed-early proteins: evidence that ICP 4 is associated with progeny virus DNA. J Gen Virol (1986) 2.30
Daxx and histone deacetylase II associate with chromatin through an interaction with core histones and the chromatin-associated protein Dek. J Cell Sci (2002) 2.30
Proteomics of herpes simplex virus replication compartments: association of cellular DNA replication, repair, recombination, and chromatin remodeling proteins with ICP8. J Virol (2004) 2.27
Specific histone tail modification and not DNA methylation is a determinant of herpes simplex virus type 1 latent gene expression. J Virol (2004) 2.25
Phenotype of a herpes simplex virus type 1 mutant that fails to express immediate-early regulatory protein ICP0. J Virol (2004) 2.03
Reactivation of latent herpes simplex virus by adenovirus recombinants encoding mutant IE-0 gene products. J Virol (1990) 2.03
p300-mediated acetylation facilitates the transfer of histone H2A-H2B dimers from nucleosomes to a histone chaperone. Genes Dev (2000) 2.03
Modulation of chromatin folding by histone acetylation. J Biol Chem (1995) 2.00
ICP0 is required for efficient reactivation of herpes simplex virus type 1 from neuronal latency. J Virol (2001) 1.96
Replication of ICP0-null mutant herpes simplex virus type 1 is restricted by both PML and Sp100. J Virol (2007) 1.95
Monoclonal antibodies define a domain on herpes simplex virus glycoprotein B involved in virus penetration. J Virol (1988) 1.94
The structure of herpes simplex virus type 1 DNA as probed by micrococcal nuclease digestion. J Gen Virol (1980) 1.94
Herpes simplex viruses with mutations in the gene encoding ICP0 are defective in gene expression. J Virol (1992) 1.92
Domain-wide displacement of histones by activated heat shock factor occurs independently of Swi/Snf and is not correlated with RNA polymerase II density. Mol Cell Biol (2005) 1.89
VP16-dependent association of chromatin-modifying coactivators and underrepresentation of histones at immediate-early gene promoters during herpes simplex virus infection. J Virol (2004) 1.89
Compartmentalization of spermine and spermidine in the herpes simplex virion. Proc Natl Acad Sci U S A (1971) 1.88
Thermolabile in vivo DNA-binding activity associated with a protein encoded by mutants of herpes simplex virus type 1. J Virol (1983) 1.86
During lytic infection herpes simplex virus type 1 is associated with histones bearing modifications that correlate with active transcription. J Virol (2004) 1.84
Perturbation of cell cycle progression and cellular gene expression as a function of herpes simplex virus ICP0. J Virol (1999) 1.84
Herpes simplex virus 1 U(L)31 and U(L)34 gene products promote the late maturation of viral replication compartments to the nuclear periphery. J Virol (2004) 1.77
ICP0 and the US3 protein kinase of herpes simplex virus 1 independently block histone deacetylation to enable gene expression. Proc Natl Acad Sci U S A (2006) 1.75
The Swi/Snf complex is important for histone eviction during transcriptional activation and RNA polymerase II elongation in vivo. Mol Cell Biol (2007) 1.72
Isolation and characterization of herpes simplex virus mutants containing engineered mutations at the DNA polymerase locus. J Virol (1990) 1.67
Temporal association of the herpes simplex virus genome with histone proteins during a lytic infection. J Virol (2007) 1.66
Trimethylation of histone H3 lysine 4 by Set1 in the lytic infection of human herpes simplex virus 1. J Virol (2006) 1.65
Human Daxx-mediated repression of human cytomegalovirus gene expression correlates with a repressive chromatin structure around the major immediate early promoter. J Biol Chem (2006) 1.64
Functional interaction between class II histone deacetylases and ICP0 of herpes simplex virus type 1. J Virol (2004) 1.59
Correct intranuclear localization of herpes simplex virus DNA polymerase requires the viral ICP8 DNA-binding protein. J Virol (1991) 1.55
High level expression and purification of herpes simplex virus type 1 immediate early polypeptide Vmw110. Nucleic Acids Res (1991) 1.51
Comparison of the intranuclear distributions of herpes simplex virus proteins involved in various viral functions. Virology (1998) 1.46
SWI/SNF displaces SAGA-acetylated nucleosomes. Eukaryot Cell (2006) 1.36
Role for A-type lamins in herpesviral DNA targeting and heterochromatin modulation. PLoS Pathog (2008) 1.26
Nuclear levels and patterns of histone H3 modification and HP1 proteins after inhibition of histone deacetylases. J Cell Sci (2005) 1.25
Chromatin regulation of virus infection. Trends Microbiol (2006) 1.25
Analysis of herpes simplex virus nucleoprotein complexes extracted from infected cells. J Virol (1980) 1.25
Altered histone H1 stoichiometry and an absence of nucleosome positioning on transfected DNA. J Biol Chem (2007) 1.14
The regulation of HIV-1 gene expression: the emerging role of chromatin. DNA Cell Biol (2002) 1.13
Nuclear sites of herpes simplex virus type 1 DNA replication and transcription colocalize at early times postinfection and are largely distinct from RNA processing factors. J Virol (1997) 1.13
Histone modifications associated with herpes simplex virus type 1 genomes during quiescence and following ICP0-mediated de-repression. J Gen Virol (2008) 1.12
Binding of ICP4, TATA-binding protein, and RNA polymerase II to herpes simplex virus type 1 immediate-early, early, and late promoters in virus-infected cells. J Virol (2007) 1.11
The coactivators CBP/p300 and the histone chaperone NAP1 promote transcription-independent nucleosome eviction at the HTLV-1 promoter. Proc Natl Acad Sci U S A (2008) 1.10
Herpes simplex virus type 1 tegument protein VP22 interacts with TAF-I proteins and inhibits nucleosome assembly but not regulation of histone acetylation by INHAT. J Gen Virol (2003) 1.05
The Swi2/Snf2 bromodomain is required for the displacement of SAGA and the octamer transfer of SAGA-acetylated nucleosomes. J Biol Chem (2006) 1.05
Intracellular organization of herpes simplex virus type 1 DNA assayed by staphylococcal nuclease sensitivity. Virus Res (1990) 1.04
Tax-dependent displacement of nucleosomes during transcriptional activation of human T-cell leukemia virus type 1. J Biol Chem (2006) 1.01
Synthesis and metabolism of cellular transcripts in HSV-1 infected cells. Virus Genes (1988) 0.89
5-Bromouracil disrupts nucleosome positioning by inducing A-form-like DNA conformation in yeast cells. Biochem Biophys Res Commun (2008) 0.86
5-Bromodeoxyuridine suppresses position effect variegation of transgenes in HeLa cells. Exp Cell Res (2001) 0.78
Vaginal submucosal dendritic cells, but not Langerhans cells, induce protective Th1 responses to herpes simplex virus-2. J Exp Med (2003) 3.86
Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis. Proc Natl Acad Sci U S A (2004) 3.74
Herpesviral latency-associated transcript gene promotes assembly of heterochromatin on viral lytic-gene promoters in latent infection. Proc Natl Acad Sci U S A (2005) 2.88
An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection. Nature (2005) 2.87
Proteomics of herpes simplex virus replication compartments: association of cellular DNA replication, repair, recombination, and chromatin remodeling proteins with ICP8. J Virol (2004) 2.27
Herpes simplex virus 1 has multiple mechanisms for blocking virus-induced interferon production. J Virol (2004) 2.24
Nuclear IFI16 induction of IRF-3 signaling during herpesviral infection and degradation of IFI16 by the viral ICP0 protein. Proc Natl Acad Sci U S A (2012) 2.14
Viral mimicry of Cdc2/cyclin-dependent kinase 1 mediates disruption of nuclear lamina during human cytomegalovirus nuclear egress. PLoS Pathog (2009) 1.82
Herpes simplex virus 1 U(L)31 and U(L)34 gene products promote the late maturation of viral replication compartments to the nuclear periphery. J Virol (2004) 1.77
Numerous conserved and divergent microRNAs expressed by herpes simplex viruses 1 and 2. J Virol (2010) 1.71
Comparative efficacy and immunogenicity of replication-defective, recombinant glycoprotein, and DNA vaccines for herpes simplex virus 2 infections in mice and guinea pigs. J Virol (2005) 1.68
Transcription of the herpes simplex virus latency-associated transcript promotes the formation of facultative heterochromatin on lytic promoters. J Virol (2009) 1.65
Identification and functional evaluation of cellular and viral factors involved in the alteration of nuclear architecture during herpes simplex virus 1 infection. J Virol (2005) 1.64
Recruitment of activated IRF-3 and CBP/p300 to herpes simplex virus ICP0 nuclear foci: Potential role in blocking IFN-beta induction. Virology (2006) 1.56
Neither LAT nor open reading frame P mutations increase expression of spliced or intron-containing ICP0 transcripts in mouse ganglia latently infected with herpes simplex virus. J Virol (2002) 1.46
Association of herpes simplex virus type 1 ICP8 and ICP27 proteins with cellular RNA polymerase II holoenzyme. J Virol (2002) 1.43
Herpes simplex virus 1 immediate-early and early gene expression during reactivation from latency under conditions that prevent infectious virus production. J Virol (2005) 1.35
Replication-defective viruses as vaccines and vaccine vectors. Virology (2006) 1.34
Herpes simplex virus. Front Biosci (2002) 1.32
The role of toll-like receptors in herpes simplex infection in neonates. J Infect Dis (2005) 1.32
Herpes simplex virus replication compartments can form by coalescence of smaller compartments. Virology (2003) 1.32
Nuclear interferon-inducible protein 16 promotes silencing of herpesviral and transfected DNA. Proc Natl Acad Sci U S A (2013) 1.31
Role for A-type lamins in herpesviral DNA targeting and heterochromatin modulation. PLoS Pathog (2008) 1.26
Proteomics of herpes simplex virus infected cell protein 27: association with translation initiation factors. Virology (2004) 1.24
Herpes simplex virus immediate-early ICP0 protein inhibits Toll-like receptor 2-dependent inflammatory responses and NF-kappaB signaling. J Virol (2010) 1.23
RNA signatures allow rapid identification of pathogens and antibiotic susceptibilities. Proc Natl Acad Sci U S A (2012) 1.23
Herpes simplex virus ICP27 increases translation of a subset of viral late mRNAs. J Virol (2008) 1.19
Role for herpes simplex virus 1 ICP27 in the inhibition of type I interferon signaling. Virology (2008) 1.18
Protection from herpes simplex virus (HSV)-2 infection with replication-defective HSV-2 or glycoprotein D2 vaccines in HSV-1-seropositive and HSV-1-seronegative guinea pigs. J Infect Dis (2009) 1.17
Herpesvirus tegument protein activates NF-kappaB signaling through the TRAF6 adaptor protein. Proc Natl Acad Sci U S A (2008) 1.16
Myeloid C3 determines induction of humoral responses to peripheral herpes simplex virus infection. J Immunol (2003) 1.11
Role of specific innate immune responses in herpes simplex virus infection of the central nervous system. J Virol (2011) 1.09
Genetic and molecular in vivo analysis of herpes simplex virus assembly in murine visual system neurons. J Virol (2005) 1.09
Persistent expression of chemokine and chemokine receptor RNAs at primary and latent sites of herpes simplex virus 1 infection. Virol J (2004) 1.08
Comparison of immunogenicity and protective efficacy of genital herpes vaccine candidates herpes simplex virus 2 dl5-29 and dl5-29-41L in mice and guinea pigs. Vaccine (2008) 1.08
Herpes simplex virus vectors elicit durable immune responses in the presence of preexisting host immunity. J Virol (2002) 1.06
Herpesviral replication compartments move and coalesce at nuclear speckles to enhance export of viral late mRNA. Proc Natl Acad Sci U S A (2011) 1.06
Cellular sensing of viral DNA and viral evasion mechanisms. Annu Rev Microbiol (2014) 1.05
Evidence for differences in immunologic and pathogenesis properties of herpes simplex virus 2 strains from the United States and South Africa. J Infect Dis (2011) 1.02
ICP22 is required for wild-type composition and infectivity of herpes simplex virus type 1 virions. J Virol (2006) 1.02
Ability of herpes simplex virus vectors to boost immune responses to DNA vectors and to protect against challenge by simian immunodeficiency virus. Virology (2006) 1.02
Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach. Nat Immunol (2012) 1.02
Latent herpes simplex virus infection of sensory neurons alters neuronal gene expression. J Virol (2003) 1.01
Herpes simplex virus 1 glycoprotein B and US3 collaborate to inhibit CD1d antigen presentation and NKT cell function. J Virol (2011) 1.01
Herpes simplex virus 1 microRNAs expressed abundantly during latent infection are not essential for latency in mouse trigeminal ganglia. Virology (2011) 1.01
Disruption of the U(L)41 gene in the herpes simplex virus 2 dl5-29 mutant increases its immunogenicity and protective capacity in a murine model of genital herpes. Virology (2007) 1.00
Human cytomegalovirus UL44 concentrates at the periphery of replication compartments, the site of viral DNA synthesis. J Virol (2011) 0.98
Herpes simplex virus VP16, but not ICP0, is required to reduce histone occupancy and enhance histone acetylation on viral genomes in U2OS osteosarcoma cells. J Virol (2009) 0.95
Herpes simplex virus-1 infection causes the secretion of a type I interferon-antagonizing protein and inhibits signaling at or before Jak-1 activation. Virology (2009) 0.95
A targeted RNA interference screen reveals novel epigenetic factors that regulate herpesviral gene expression. MBio (2014) 0.95
Macrophage-derived complement component C4 can restore humoral immunity in C4-deficient mice. J Immunol (2002) 0.94
Type 3 reovirus neuroinvasion after intramuscular inoculation: direct invasion of nerve terminals and age-dependent pathogenesis. Virology (2002) 0.94
Immunization with a replication-defective herpes simplex virus 2 mutant reduces herpes simplex virus 1 infection and prevents ocular disease. Virology (2007) 0.94
ICP27 selectively regulates the cytoplasmic localization of a subset of viral transcripts in herpes simplex virus type 1-infected cells. J Virol (2004) 0.93
Inhibitors of the sodium potassium ATPase that impair herpes simplex virus replication identified via a chemical screening approach. Virology (2007) 0.93
Palmitoylation of the cysteine-rich endodomain of the SARS-coronavirus spike glycoprotein is important for spike-mediated cell fusion. Virology (2006) 0.93
Herpes simplex virus and toll-like receptors. Viral Immunol (2005) 0.92
Properties of a herpes simplex virus multiple immediate-early gene-deleted recombinant as a vaccine vector. Virology (2006) 0.92
Genetic analysis of the SARS-coronavirus spike glycoprotein functional domains involved in cell-surface expression and cell-to-cell fusion. Virology (2005) 0.90
Optimal long-term humoral responses to replication-defective herpes simplex virus require CD21/CD35 complement receptor expression on stromal cells. J Virol (2006) 0.90
Evidence for a direct interaction between HSV-1 ICP27 and ICP8 proteins. Virology (2005) 0.89
Cellular SNF2H chromatin-remodeling factor promotes herpes simplex virus 1 immediate-early gene expression and replication. MBio (2011) 0.87
Discovery of a novel TLR2 signaling inhibitor with anti-viral activity. Antiviral Res (2010) 0.86
C-terminal region of herpes simplex virus ICP8 protein needed for intranuclear localization. Virology (2003) 0.86
Herpes simplex virus US3 tegument protein inhibits Toll-like receptor 2 signaling at or before TRAF6 ubiquitination. Virology (2013) 0.86
Identification of a divalent metal cation binding site in herpes simplex virus 1 (HSV-1) ICP8 required for HSV replication. J Virol (2012) 0.86
Simian TRIM5alpha proteins reduce replication of herpes simplex virus. Virology (2010) 0.84
Conformational changes in the herpes simplex virus ICP8 DNA-binding protein coincident with assembly in viral replication structures. J Virol (2003) 0.84
Genetic engineering of a modified herpes simplex virus 1 vaccine vector. Vaccine (2009) 0.83
CD200R1 supports HSV-1 viral replication and licenses pro-inflammatory signaling functions of TLR2. PLoS One (2012) 0.82
Construction and properties of a herpes simplex virus 2 dl5-29 vaccine candidate strain encoding an HSV-1 virion host shutoff protein. Vaccine (2010) 0.81
Roles of the nuclear lamina in stable nuclear association and assembly of a herpesviral transactivator complex on viral immediate-early genes. MBio (2012) 0.80
Type 3 reovirus neuroinvasion after intramuscular inoculation: viral genetic determinants of lethality and spinal cord infection. Virology (2002) 0.77
Herpes simplex virus as a tool to define the role of complement in the immune response to peripheral infection. Vaccine (2008) 0.76
The use of green fluorescent fusion proteins to monitor herpes simplex virus replication. Methods Mol Biol (2009) 0.76
Decreasing herpes simplex viral infectivity in solution by surface-immobilized and suspended N,N-dodecyl,methyl-polyethylenimine. Pharm Res (2012) 0.75
[Application of herpes simplex virus to HIV vaccine vector]. Nihon Rinsho (2006) 0.75