Human cytomegalovirus persistence.

PubWeight™: 1.16‹?› | Rank: Top 10%

🔗 View Article (PMC 3330195)

Published in Cell Microbiol on March 08, 2012

Authors

Felicia Goodrum1, Katie Caviness, Patricia Zagallo

Author Affiliations

1: Department of Immunobiology, University of Arizona, Tucson, AZ 85719, USA.

Articles citing this

Cytomegalovirus infection enhances the immune response to influenza. Sci Transl Med (2015) 1.83

SAMHD1 restricts herpes simplex virus 1 in macrophages by limiting DNA replication. J Virol (2013) 1.09

An endothelial cell-specific requirement for the UL133-UL138 locus of human cytomegalovirus for efficient virus maturation. J Virol (2013) 1.00

Human Cytomegalovirus UL135 and UL136 Genes Are Required for Postentry Tropism in Endothelial Cells. J Virol (2015) 0.95

Human cytomegalovirus induction of a unique signalsome during viral entry into monocytes mediates distinct functional changes: a strategy for viral dissemination. J Leukoc Biol (2012) 0.94

Tale of a tegument transactivator: the past, present and future of human CMV pp71. Future Virol (2012) 0.94

Molecular mechanisms deployed by virally encoded G protein-coupled receptors in human diseases. Annu Rev Pharmacol Toxicol (2012) 0.92

Human embryonic stem cell lines model experimental human cytomegalovirus latency. MBio (2013) 0.92

Myeloblastic cell lines mimic some but not all aspects of human cytomegalovirus experimental latency defined in primary CD34+ cell populations. J Virol (2013) 0.89

Human Cytomegalovirus Latency: Approaching the Gordian Knot. Annu Rev Virol (2016) 0.86

Maintenance of large numbers of virus genomes in human cytomegalovirus-infected T98G glioblastoma cells. J Virol (2014) 0.84

Release of human cytomegalovirus from latency by a KAP1/TRIM28 phosphorylation switch. Elife (2015) 0.83

Cell-mediated immunity to human CMV infection: a brief overview. F1000Prime Rep (2014) 0.83

Comprehensive analysis of human cytomegalovirus microRNA expression during lytic and quiescent infection. PLoS One (2014) 0.82

Heterologous viral promoters incorporated into the human cytomegalovirus genome are silenced during experimental latency. J Virol (2013) 0.82

The ULb' region of the human cytomegalovirus genome confers an increased requirement for the viral protein kinase UL97. J Virol (2013) 0.82

Systematic microRNA analysis identifies ATP6V0C as an essential host factor for human cytomegalovirus replication. PLoS Pathog (2013) 0.82

Delay in cART initiation results in persistent immune dysregulation and poor recovery of T-cell phenotype despite a decade of successful HIV suppression. PLoS One (2014) 0.80

Seroepidemiology of cytomegalovirus infection in pregnant women in Durango City, Mexico. BMC Infect Dis (2014) 0.78

Complex Interplay of the UL136 Isoforms Balances Cytomegalovirus Replication and Latency. MBio (2016) 0.78

Infectious hematopoietic necrosis virus (IHNV) persistence in Sockeye Salmon: influence on brain transcriptome and subsequent response to the viral mimic poly(I:C). BMC Genomics (2015) 0.77

Emerging Roles of Herpesvirus microRNAs During In Vivo Infection and Pathogenesis. Curr Pathobiol Rep (2015) 0.77

Inactivation of the Human Cytomegalovirus US20 Gene Hampers Productive Viral Replication in Endothelial Cells. J Virol (2015) 0.77

HCMV requires EGFR signaling to enter and initiate the early steps in the establishment of latency in CD34+ human progenitor cells. J Virol (2016) 0.76

Insertion of myeloid-active elements into the human cytomegalovirus major immediate early promoter is not sufficient to drive its activation upon infection of undifferentiated myeloid cells. Virology (2013) 0.76

Opposing Regulation of the EGF Receptor: A Molecular Switch Controlling Cytomegalovirus Latency and Replication. PLoS Pathog (2016) 0.76

Vascular dysfunction in young, mid-aged and aged mice with latent cytomegalovirus infections. Am J Physiol Heart Circ Physiol (2012) 0.76

Human cytomegalovirus interleukin-10 enhances matrigel invasion of MDA-MB-231 breast cancer cells. Cancer Cell Int (2017) 0.75

Effect of human cytomegalovirus (HCMV) US27 on CXCR4 receptor internalization measured by fluorogen-activating protein (FAP) biosensors. PLoS One (2017) 0.75

Tissue reservoirs of antiviral T cell immunity in persistent human CMV infection. J Exp Med (2017) 0.75

Long and Short Isoforms of the Human Cytomegalovirus UL138 Protein Silence IE Transcription and Promote Latency. J Virol (2016) 0.75

Two Polypyrimidine Tracts in Intron 4 of the Major Immediate Early Gene Are Critical for Gene Expression Switching from IE1 to IE2 and for Replication of Human Cytomegalovirus. J Virol (2016) 0.75

Chemokines encoded by herpesviruses. J Leukoc Biol (2017) 0.75

Lack of Association Between Cytomegalovirus Infection and Hypertensive Disorders in Pregnancy: A Case-Control Study in Durango, Mexico. Eur J Microbiol Immunol (Bp) (2017) 0.75

The host ubiquitin-dependent segregase VCP/p97 is required for the onset of human cytomegalovirus replication. PLoS Pathog (2017) 0.75

Articles cited by this

(truncated to the top 100)

MicroRNAs expressed by herpes simplex virus 1 during latent infection regulate viral mRNAs. Nature (2008) 5.29

Host immune system gene targeting by a viral miRNA. Science (2007) 5.10

Intrinsic immunity: a front-line defense against viral attack. Nat Immunol (2004) 4.95

Functional map of human cytomegalovirus AD169 defined by global mutational analysis. Proc Natl Acad Sci U S A (2003) 4.21

Evasion of CD8+ T cells is critical for superinfection by cytomegalovirus. Science (2010) 3.31

PML and PML nuclear bodies: implications in antiviral defence. Biochimie (2007) 3.26

Nuclear domain 10, the site of DNA virus transcription and replication. Bioessays (1998) 3.13

Suppression of immediate-early viral gene expression by herpesvirus-coded microRNAs: implications for latency. Proc Natl Acad Sci U S A (2008) 2.90

Herpesviral latency-associated transcript gene promotes assembly of heterochromatin on viral lytic-gene promoters in latent infection. Proc Natl Acad Sci U S A (2005) 2.88

Human cytomegalovirus latent gene expression in granulocyte-macrophage progenitors in culture and in seropositive individuals. Proc Natl Acad Sci U S A (1996) 2.87

Chromatin control of herpes simplex virus lytic and latent infection. Nat Rev Microbiol (2008) 2.86

The major immediate-early proteins IE1 and IE2 of human cytomegalovirus colocalize with and disrupt PML-associated nuclear bodies at very early times in infected permissive cells. J Virol (1997) 2.83

Epidermal growth factor receptor is a cellular receptor for human cytomegalovirus. Nature (2003) 2.77

Identification and characterization of human cytomegalovirus-encoded microRNAs. J Virol (2005) 2.73

The nuclear domain 10 (ND10) is disrupted by the human cytomegalovirus gene product IE1. Exp Cell Res (1996) 2.69

Manifestations of human cytomegalovirus infection: proposed mechanisms of acute and chronic disease. Curr Top Microbiol Immunol (2008) 2.52

Evidence for a role of the cellular ND10 protein PML in mediating intrinsic immunity against human cytomegalovirus infections. J Virol (2006) 2.41

Latency, chromatin remodeling, and reactivation of human cytomegalovirus in the dendritic cells of healthy carriers. Proc Natl Acad Sci U S A (2005) 2.34

Human cytomegalovirus open reading frame US28 encodes a functional beta chemokine receptor. J Biol Chem (1994) 2.34

Inactivating a cellular intrinsic immune defense mediated by Daxx is the mechanism through which the human cytomegalovirus pp71 protein stimulates viral immediate-early gene expression. J Virol (2006) 2.32

Breast milk and the risk of cytomegalovirus infection. N Engl J Med (1980) 2.27

A human cytomegalovirus-encoded microRNA regulates expression of multiple viral genes involved in replication. PLoS Pathog (2007) 2.26

Human cytomegalovirus gene expression during infection of primary hematopoietic progenitor cells: a model for latency. Proc Natl Acad Sci U S A (2002) 2.15

Control of cytomegalovirus lytic gene expression by histone acetylation. EMBO J (2002) 2.06

The epigenetic landscape of latent Kaposi sarcoma-associated herpesvirus genomes. PLoS Pathog (2010) 1.97

Evasion of cellular antiviral responses by human cytomegalovirus TRS1 and IRS1. J Virol (2004) 1.96

Epigenetic analysis of KSHV latent and lytic genomes. PLoS Pathog (2010) 1.94

Herpes simplex virus ICP0 promotes both histone removal and acetylation on viral DNA during lytic infection. J Virol (2008) 1.88

Cytomegalovirus: pathogen, paradigm, and puzzle. J Clin Invest (2011) 1.82

New insights into the role of the subnuclear structure ND10 for viral infection. Biochim Biophys Acta (2008) 1.82

Daxx-mediated accumulation of human cytomegalovirus tegument protein pp71 at ND10 facilitates initiation of viral infection at these nuclear domains. J Virol (2002) 1.81

Cytomegalovirus immune evasion. Curr Top Microbiol Immunol (2008) 1.80

Granulocyte-colony stimulating factor reactivates human cytomegalovirus in a latently infected humanized mouse model. Cell Host Microbe (2010) 1.77

Human cytomegalovirus sequences expressed in latently infected individuals promote a latent infection in vitro. Blood (2007) 1.73

HCMV-encoded chemokine receptor US28 mediates proliferative signaling through the IL-6-STAT3 axis. Sci Signal (2010) 1.72

Viral latency and its regulation: lessons from the gamma-herpesviruses. Cell Host Microbe (2010) 1.70

Epigenetic regulation of latent HSV-1 gene expression. Biochim Biophys Acta (2010) 1.65

Transcription of the herpes simplex virus latency-associated transcript promotes the formation of facultative heterochromatin on lytic promoters. J Virol (2009) 1.65

Human Daxx-mediated repression of human cytomegalovirus gene expression correlates with a repressive chromatin structure around the major immediate early promoter. J Biol Chem (2006) 1.64

Nuclear domain 10 components promyelocytic leukemia protein and hDaxx independently contribute to an intrinsic antiviral defense against human cytomegalovirus infection. J Virol (2007) 1.61

Human cytomegalovirus gene expression is silenced by Daxx-mediated intrinsic immune defense in model latent infections established in vitro. J Virol (2007) 1.60

Focal transcriptional activity of murine cytomegalovirus during latency in the lungs. J Virol (1999) 1.59

A novel viral transcript with homology to human interleukin-10 is expressed during latent human cytomegalovirus infection. J Virol (2004) 1.57

Human cytomegalovirus (HCMV) UL82 gene product (pp71) relieves hDaxx-mediated repression of HCMV replication. J Virol (2006) 1.55

The polycomb group protein Bmi1 binds to the herpes simplex virus 1 latent genome and maintains repressive histone marks during latency. J Virol (2009) 1.53

Role of the cellular protein hDaxx in human cytomegalovirus immediate-early gene expression. J Gen Virol (2006) 1.52

Activation of EGFR on monocytes is required for human cytomegalovirus entry and mediates cellular motility. Proc Natl Acad Sci U S A (2009) 1.51

The cytomegalovirus-encoded chemokine receptor US28 promotes intestinal neoplasia in transgenic mice. J Clin Invest (2010) 1.50

Differential outcomes of human cytomegalovirus infection in primitive hematopoietic cell subpopulations. Blood (2004) 1.49

Transcriptome analysis reveals human cytomegalovirus reprograms monocyte differentiation toward an M1 macrophage. J Immunol (2008) 1.48

Proteasome-dependent, ubiquitin-independent degradation of Daxx by the viral pp71 protein in human cytomegalovirus-infected cells. Virology (2007) 1.48

The human cytomegalovirus microRNA miR-UL112 acts synergistically with a cellular microRNA to escape immune elimination. Nat Immunol (2010) 1.48

Lytic but not latent replication of epstein-barr virus is associated with PML and induces sequential release of nuclear domain 10 proteins. J Virol (2000) 1.47

Conserved herpesvirus kinases target the DNA damage response pathway and TIP60 histone acetyltransferase to promote virus replication. Cell Host Microbe (2011) 1.43

Interaction between the human cytomegalovirus UL82 gene product (pp71) and hDaxx regulates immediate-early gene expression and viral replication. J Virol (2005) 1.39

The cytomegalovirus US28 protein binds multiple CC chemokines with high affinity. Biochem Biophys Res Commun (1995) 1.39

Mouse models of cytomegalovirus latency: overview. J Clin Virol (2002) 1.37

Essential role for either TRS1 or IRS1 in human cytomegalovirus replication. J Virol (2009) 1.37

Human cytomegalovirus protein pp71 displaces the chromatin-associated factor ATRX from nuclear domain 10 at early stages of infection. J Virol (2008) 1.36

Temporal dynamics of cytomegalovirus chromatin assembly in productively infected human cells. J Virol (2008) 1.35

Asymptomatic primary cytomegalovirus infection: virologic and immunologic features. J Infect Dis (1999) 1.34

Characterization of an antisense transcript spanning the UL81-82 locus of human cytomegalovirus. J Virol (2005) 1.32

Analysis of latent viral gene expression in natural and experimental latency models of human cytomegalovirus and its correlation with histone modifications at a latent promoter. J Gen Virol (2009) 1.31

A novel human cytomegalovirus locus modulates cell type-specific outcomes of infection. PLoS Pathog (2011) 1.30

Characterization of a novel Golgi apparatus-localized latency determinant encoded by human cytomegalovirus. J Virol (2009) 1.29

Autorepression of the human cytomegalovirus major immediate-early promoter/enhancer at late times of infection is mediated by the recruitment of chromatin remodeling enzymes by IE86. J Virol (2006) 1.29

Stress-inducible alternative translation initiation of human cytomegalovirus latency protein pUL138. J Virol (2010) 1.29

Cellular and viral control over the initial events of human cytomegalovirus experimental latency in CD34+ cells. J Virol (2010) 1.29

Epstein-Barr virus LMP1 activates EGFR, STAT3, and ERK through effects on PKCdelta. J Virol (2011) 1.28

Nonprimate models of congenital cytomegalovirus (CMV) infection: gaining insight into pathogenesis and prevention of disease in newborns. ILAR J (2006) 1.28

Mechanisms of cytomegalovirus-accelerated vascular disease: induction of paracrine factors that promote angiogenesis and wound healing. Curr Top Microbiol Immunol (2008) 1.27

Experimental human cytomegalovirus latency in CD14+ monocytes. Proc Natl Acad Sci U S A (2010) 1.26

Intrinsic cellular defense mechanisms targeting human cytomegalovirus. Virus Res (2010) 1.26

Human CMV infection of endothelial cells induces an angiogenic response through viral binding to EGF receptor and beta1 and beta3 integrins. Proc Natl Acad Sci U S A (2008) 1.25

Analysis of human cytomegalovirus-encoded microRNA activity during infection. J Virol (2009) 1.22

Viral gene expression during the establishment of human cytomegalovirus latent infection in myeloid progenitor cells. Blood (2006) 1.22

Report from the second cytomegalovirus and immunosenescence workshop. Immun Ageing (2011) 1.19

Frequency and duration of plasma CMV viremia in seroconverting blood donors and recipients. Transfusion (2003) 1.19

Antiviral inhibition targeting the HCMV kinase pUL97 requires pUL27-dependent degradation of Tip60 acetyltransferase and cell-cycle arrest. Cell Host Microbe (2011) 1.19

Human cytomegalovirus chemokine receptor gene US28 is transcribed in latently infected THP-1 monocytes. J Virol (2001) 1.18

The cytomegaloviral protein pUL138 acts as potentiator of tumor necrosis factor (TNF) receptor 1 surface density to enhance ULb'-encoded modulation of TNF-α signaling. J Virol (2011) 1.17

Pivotal role of animal models in the development of new therapies for cytomegalovirus infections. Antiviral Res (2006) 1.16

During herpes simplex virus type 1 infection of rabbits, the ability to express the latency-associated transcript increases latent-phase transcription of lytic genes. J Virol (2008) 1.14

Rhesus CMV: an emerging animal model for human CMV. Med Microbiol Immunol (2008) 1.14

Virally induced changes in cellular microRNAs maintain latency of human cytomegalovirus in CD34⁺ progenitors. J Gen Virol (2011) 1.13

Inhibition of programmed cell death by cytomegaloviruses. Virus Res (2010) 1.12

Attenuation of innate immunity by cytomegalovirus IL-10 establishes a long-term deficit of adaptive antiviral immunity. Proc Natl Acad Sci U S A (2010) 1.12

The role of the human cytomegalovirus UL111A gene in down-regulating CD4+ T-cell recognition of latently infected cells: implications for virus elimination during latency. Blood (2009) 1.11

PI3K-dependent upregulation of Mcl-1 by human cytomegalovirus is mediated by epidermal growth factor receptor and inhibits apoptosis in short-lived monocytes. J Immunol (2010) 1.10

Human cytomegalovirus modulation of signal transduction. Curr Top Microbiol Immunol (2008) 1.10

Transcriptome analysis of NF-kappaB- and phosphatidylinositol 3-kinase-regulated genes in human cytomegalovirus-infected monocytes. J Virol (2007) 1.09

Subversion of cell cycle regulatory pathways. Curr Top Microbiol Immunol (2008) 1.09

Inhibition of inflammatory interleukin-6 activity via extracellular signal-regulated kinase-mitogen-activated protein kinase signaling antagonizes human cytomegalovirus reactivation from dendritic cells. J Virol (2011) 1.08

The latency-associated UL138 gene product of human cytomegalovirus sensitizes cells to tumor necrosis factor alpha (TNF-alpha) signaling by upregulating TNF-alpha receptor 1 cell surface expression. J Virol (2011) 1.08

Human cytomegalovirus latency-associated protein pORF94 is dispensable for productive and latent infection. J Virol (2000) 1.07

Viral interleukin-10 expressed by human cytomegalovirus during the latent phase of infection modulates latently infected myeloid cell differentiation. J Virol (2011) 1.06

Human cytomegalovirus-induced inhibition of cytotrophoblast invasion in a first trimester extravillous cytotrophoblast cell line. Placenta (2005) 1.05

Rat cytomegalovirus gene expression in cardiac allograft recipients is tissue specific and does not parallel the profiles detected in vitro. J Virol (2007) 1.05

Human cytomegalovirus activation of ERK and myeloid cell leukemia-1 protein correlates with survival of latently infected cells. Proc Natl Acad Sci U S A (2011) 1.03

Evidence for a dual antiviral role of the major nuclear domain 10 component Sp100 during the immediate-early and late phases of the human cytomegalovirus replication cycle. J Virol (2011) 1.03