Published in J Virol on February 10, 2010
A viral ubiquitin ligase has substrate preferential SUMO targeted ubiquitin ligase activity that counteracts intrinsic antiviral defence. PLoS Pathog (2011) 1.47
The differential mobilization of histones H3.1 and H3.3 by herpes simplex virus 1 relates histone dynamics to the assembly of viral chromatin. PLoS Pathog (2013) 1.42
Latency Entry of Herpes Simplex Virus 1 Is Determined by the Interaction of Its Genome with the Nuclear Environment. PLoS Pathog (2016) 1.39
The intrinsic antiviral defense to incoming HSV-1 genomes includes specific DNA repair proteins and is counteracted by the viral protein ICP0. PLoS Pathog (2011) 1.37
PML isoforms I and II participate in PML-dependent restriction of HSV-1 replication. J Cell Sci (2010) 1.35
Comparison of the biological and biochemical activities of several members of the alphaherpesvirus ICP0 family of proteins. J Virol (2010) 1.32
Human pathogens and the host cell SUMOylation system. J Virol (2011) 1.31
Nuclear interferon-inducible protein 16 promotes silencing of herpesviral and transfected DNA. Proc Natl Acad Sci U S A (2013) 1.31
SUMO pathway dependent recruitment of cellular repressors to herpes simplex virus type 1 genomes. PLoS Pathog (2011) 1.30
Interplay between viruses and host sumoylation pathways. Nat Rev Microbiol (2013) 1.26
Proteasome-dependent degradation of Daxx by the viral E1B-55K protein in human adenovirus-infected cells. J Virol (2010) 1.23
Components of promyelocytic leukemia nuclear bodies (ND10) act cooperatively to repress herpesvirus infection. J Virol (2012) 1.16
EBV tegument protein BNRF1 disrupts DAXX-ATRX to activate viral early gene transcription. PLoS Pathog (2011) 1.14
The viral ubiquitin ligase ICP0 is neither sufficient nor necessary for degradation of the cellular DNA sensor IFI16 during herpes simplex virus 1 infection. J Virol (2013) 1.14
Transcriptional activation of the adenoviral genome is mediated by capsid protein VI. PLoS Pathog (2012) 1.06
Activities of ICP0 involved in the reversal of silencing of quiescent herpes simplex virus 1. J Virol (2011) 1.05
Single-cell analysis of Daxx and ATRX-dependent transcriptional repression. J Cell Sci (2012) 1.02
DNA mismatch repair proteins are required for efficient herpes simplex virus 1 replication. J Virol (2011) 0.99
HSV-1 genome subnuclear positioning and associations with host-cell PML-NBs and centromeres regulate LAT locus transcription during latency in neurons. PLoS Pathog (2012) 0.98
Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression. Mol Cell Proteomics (2015) 0.98
HSV-1 ICP0: An E3 Ubiquitin Ligase That Counteracts Host Intrinsic and Innate Immunity. Cells (2014) 0.96
3D reconstruction of VZV infected cell nuclei and PML nuclear cages by serial section array scanning electron microscopy and electron tomography. PLoS Pathog (2012) 0.96
Retroviral DNA methylation and epigenetic repression are mediated by the antiviral host protein Daxx. J Virol (2012) 0.95
Adenovirus type 5 early region 1B 55K oncoprotein-dependent degradation of cellular factor Daxx is required for efficient transformation of primary rodent cells. J Virol (2011) 0.95
A targeted RNA interference screen reveals novel epigenetic factors that regulate herpesviral gene expression. MBio (2014) 0.95
The Emerging Role of Nuclear Viral DNA Sensors. J Biol Chem (2015) 0.94
HSV-1 ICP0: paving the way for viral replication. Future Virol (2011) 0.94
Virion factors that target Daxx to overcome intrinsic immunity. J Virol (2013) 0.93
ICP0 dismantles microtubule networks in herpes simplex virus-infected cells. PLoS One (2010) 0.93
Control of human adenovirus type 5 gene expression by cellular Daxx/ATRX chromatin-associated complexes. Nucleic Acids Res (2013) 0.93
A comparison of herpes simplex virus type 1 and varicella-zoster virus latency and reactivation. J Gen Virol (2015) 0.93
The PML-Interacting Protein DAXX: Histone Loading Gets into the Picture. Front Oncol (2013) 0.91
The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA. Mol Syst Biol (2015) 0.90
Uncoupling uncoating of herpes simplex virus genomes from their nuclear import and gene expression. J Virol (2011) 0.90
Efficient herpes simplex virus 1 replication requires cellular ATR pathway proteins. J Virol (2012) 0.89
DNA sensing-independent inhibition of herpes simplex virus 1 replication by DAI/ZBP1. J Virol (2013) 0.89
The spatial organization of DNA virus genomes in the nucleus. PLoS Pathog (2013) 0.89
Herpes simplex virus is equipped with RNA- and protein-based mechanisms to repress expression of ATRX, an effector of intrinsic immunity. J Virol (2012) 0.88
ATRX represses alternative lengthening of telomeres. Oncotarget (2015) 0.88
Chromatin dynamics during lytic infection with herpes simplex virus 1. Viruses (2013) 0.87
Dynamic Response of IFI16 and Promyelocytic Leukemia Nuclear Body Components to Herpes Simplex Virus 1 Infection. J Virol (2015) 0.87
Dynamic modulation of HSV chromatin drives initiation of infection and provides targets for epigenetic therapies. Virology (2015) 0.87
Influence of ND10 components on epigenetic determinants of early KSHV latency establishment. PLoS Pathog (2014) 0.86
The replication defect of ICP0-null mutant herpes simplex virus 1 can be largely complemented by the combined activities of human cytomegalovirus proteins IE1 and pp71. J Virol (2012) 0.86
Sp100A promotes chromatin decondensation at a cytomegalovirus-promoter-regulated transcription site. Mol Biol Cell (2013) 0.86
Changing the ubiquitin landscape during viral manipulation of the DNA damage response. FEBS Lett (2011) 0.86
Analysis of the SUMO2 Proteome during HSV-1 Infection. PLoS Pathog (2015) 0.85
The potential link between PML NBs and ICP0 in regulating lytic and latent infection of HSV-1. Protein Cell (2012) 0.85
Structure of the herpes simplex virus 1 genome: manipulation of nicks and gaps can abrogate infectivity and alter the cellular DNA damage response. J Virol (2014) 0.84
Depletion of CoREST does not improve the replication of ICP0 null mutant herpes simplex virus type 1. J Virol (2010) 0.84
Viral reprogramming of the Daxx histone H3.3 chaperone during early Epstein-Barr virus infection. J Virol (2014) 0.83
Herpes simplex virus 1 ICP0 phosphorylation site mutants are attenuated for viral replication and impaired for explant-induced reactivation. J Virol (2011) 0.83
Interaction of herpes simplex virus ICP0 with ND10 bodies: a sequential process of adhesion, fusion, and retention. J Virol (2013) 0.83
HSV-1 remodels host telomeres to facilitate viral replication. Cell Rep (2014) 0.82
Early nucleosome deposition on, and replication of, HSV DNA requires cell factor PCNA. J Neurovirol (2015) 0.81
A Herpesviral Lytic Protein Regulates the Structure of Latent Viral Chromatin. MBio (2016) 0.80
Nuclear domain 10 of the viral aspect. World J Virol (2013) 0.80
The herpes simplex virus immediate-early ubiquitin ligase ICP0 induces degradation of the ICP0 repressor protein E2FBP1. J Virol (2011) 0.80
Role of ND10 nuclear bodies in the chromatin repression of HSV-1. Virol J (2016) 0.78
Time-resolved Global and Chromatin Proteomics during Herpes Simplex Virus Type 1 (HSV-1) Infection. Mol Cell Proteomics (2017) 0.78
Alterations of Nuclear Architecture and Epigenetic Signatures during African Swine Fever Virus Infection. Viruses (2015) 0.78
Single cell analysis of RNA-mediated histone H3.3 recruitment to a cytomegalovirus promoter-regulated transcription site. J Biol Chem (2013) 0.78
Identification of three redundant segments responsible for herpes simplex virus 1 ICP0 to fuse with ND10 nuclear bodies. J Virol (2015) 0.78
An Intrinsically Disordered Region of the DNA Repair Protein Nbs1 Is a Species-Specific Barrier to Herpes Simplex Virus 1 in Primates. Cell Host Microbe (2016) 0.77
Resident T Cells Are Unable To Control Herpes Simplex Virus-1 Activity in the Brain Ependymal Region during Latency. J Immunol (2016) 0.77
Analysis of the functional interchange between the IE1 and pp71 proteins of human cytomegalovirus and ICP0 of herpes simplex virus 1. J Virol (2014) 0.77
Comparative analysis of the ATRX promoter and 5' regulatory region reveals conserved regulatory elements which are linked to roles in neurodevelopment, alpha-globin regulation and testicular function. BMC Res Notes (2011) 0.76
The chicken adenovirus Gam1 protein, an inhibitor of the sumoylation pathway, partially complements ICP0-null mutant herpes simplex virus 1. J Virol (2014) 0.76
An Adenovirus DNA Replication Factor, but Not Incoming Genome Complexes, Targets PML Nuclear Bodies. J Virol (2015) 0.76
The Role of Nuclear Antiviral Factors against Invading DNA Viruses: The Immediate Fate of Incoming Viral Genomes. Viruses (2016) 0.76
Chromatin Modulation of Herpesvirus Lytic Gene Expression: Managing Nucleosome Density and Heterochromatic Histone Modifications. MBio (2016) 0.76
The use of fluorescence microscopy to study the association between herpesviruses and intrinsic resistance factors. Viruses (2011) 0.76
Analyses of herpes simplex virus type 1 latency and reactivation at the single cell level using fluorescent reporter mice. J Gen Virol (2015) 0.76
RNase P protein subunit Rpp29 represses histone H3.3 nucleosome deposition. Mol Biol Cell (2016) 0.75
Cellular Transcriptional Coactivator RanBP10 and Herpes Simplex Virus 1 ICP0 Interact and Synergistically Promote Viral Gene Expression and Replication. J Virol (2016) 0.75
The SUMOylation Pathway Restricts Gene Transduction by Adeno-Associated Viruses. PLoS Pathog (2015) 0.75
MORC3, a Component of PML Nuclear Bodies, Has a Role in Restricting Herpes Simplex Virus 1 and Human Cytomegalovirus. J Virol (2016) 0.75
Host cell restriction factors that limit transcription and replication of human papillomavirus. Virus Res (2016) 0.75
Stimulation of the Replication of ICP0-Null Mutant Herpes Simplex Virus 1 and pp71-Deficient Human Cytomegalovirus by Epstein-Barr Virus Tegument Protein BNRF1. J Virol (2016) 0.75
Mutations Inactivating Herpes Simplex Virus-1 miR-H2 Do Not Detectably Increase ICP0 Gene Expression in Infected Cultured Cells or Mouse Trigeminal Ganglia. J Virol (2016) 0.75
Histone Deacetylase Inhibitors Reduce the Number of Herpes Simplex Virus-1 Genomes Initiating Expression in Individual Cells. Front Microbiol (2016) 0.75
The essential role of guinea pig cytomegalovirus (GPCMV) IE1 and IE2 homologs in viral replication and IE1-mediated ND10 targeting. Virology (2017) 0.75
Isolation and characterization of a herpes simplex virus type 1 mutant containing a deletion within the gene encoding the immediate early polypeptide Vmw110. J Gen Virol (1986) 6.74
Gene splicing and mutagenesis by PCR-driven overlap extension. Nat Protoc (2007) 6.11
PML is critical for ND10 formation and recruits the PML-interacting protein daxx to this nuclear structure when modified by SUMO-1. J Cell Biol (1999) 5.83
A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors. EMBO J (1996) 4.65
HSV-1 IE protein Vmw110 causes redistribution of PML. EMBO J (1994) 4.61
Infection of a human hepatoma cell line by hepatitis B virus. Proc Natl Acad Sci U S A (2002) 4.52
The disruption of ND10 during herpes simplex virus infection correlates with the Vmw110- and proteasome-dependent loss of several PML isoforms. J Virol (1998) 4.43
Daxx, a novel Fas-binding protein that activates JNK and apoptosis. Cell (1997) 4.39
Modification of discrete nuclear domains induced by herpes simplex virus type 1 immediate early gene 1 product (ICP0). J Gen Virol (1993) 4.32
Herpes simplex virus type 1 immediate-early protein ICP0 and is isolated RING finger domain act as ubiquitin E3 ligases in vitro. J Virol (2002) 4.06
Role of SUMO-1-modified PML in nuclear body formation. Blood (2000) 4.05
The periphery of nuclear domain 10 (ND10) as site of DNA virus deposition. J Cell Biol (1996) 3.91
A monoclonal antibody recognizing nuclear matrix-associated nuclear bodies. J Cell Sci (1992) 3.91
PIC 1, a novel ubiquitin-like protein which interacts with the PML component of a multiprotein complex that is disrupted in acute promyelocytic leukaemia. Oncogene (1996) 3.73
Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx. Science (1998) 3.72
Nuclear domain 10 as preexisting potential replication start sites of herpes simplex virus type-1. Virology (1996) 3.62
The ATRX syndrome protein forms a chromatin-remodeling complex with Daxx and localizes in promyelocytic leukemia nuclear bodies. Proc Natl Acad Sci U S A (2003) 3.52
Herpes virus induced proteasome-dependent degradation of the nuclear bodies-associated PML and Sp100 proteins. Oncogene (1999) 3.41
A novel ubiquitin-specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory protein. EMBO J (1997) 3.34
Role of SUMO-interacting motif in Daxx SUMO modification, subnuclear localization, and repression of sumoylated transcription factors. Mol Cell (2006) 3.26
Herpes simplex virus type 1 ICP0 regulates expression of immediate-early, early, and late genes in productively infected cells. J Virol (1992) 3.10
Mutations in a putative global transcriptional regulator cause X-linked mental retardation with alpha-thalassemia (ATR-X syndrome). Cell (1995) 3.09
ICP0, a regulator of herpes simplex virus during lytic and latent infection. Bioessays (2000) 3.09
PML contributes to a cellular mechanism of repression of herpes simplex virus type 1 infection that is inactivated by ICP0. J Virol (2006) 3.03
Persistence and expression of the herpes simplex virus genome in the absence of immediate-early proteins. J Virol (1998) 2.97
Critical role for Daxx in regulating Mdm2. Nat Cell Biol (2006) 2.96
Chromatin control of herpes simplex virus lytic and latent infection. Nat Rev Microbiol (2008) 2.86
An activity specified by the osteosarcoma line U2OS can substitute functionally for ICP0, a major regulatory protein of herpes simplex virus type 1. J Virol (1995) 2.82
Specific destruction of kinetochore protein CENP-C and disruption of cell division by herpes simplex virus immediate-early protein Vmw110. EMBO J (1999) 2.79
Herpes simplex virus type 1 immediate-early protein Vmw110 reactivates latent herpes simplex virus type 2 in an in vitro latency system. J Virol (1989) 2.76
Role of ICP0 in the strategy of conquest of the host cell by herpes simplex virus 1. J Virol (2004) 2.69
Components of the REST/CoREST/histone deacetylase repressor complex are disrupted, modified, and translocated in HSV-1-infected cells. Proc Natl Acad Sci U S A (2005) 2.67
Sequestration and inhibition of Daxx-mediated transcriptional repression by PML. Mol Cell Biol (2000) 2.59
Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX-DNMT3-DNMT3L domain. EMBO Rep (2009) 2.50
Herpes simplex virus-infected cell protein 0 blocks the silencing of viral DNA by dissociating histone deacetylases from the CoREST-REST complex. Proc Natl Acad Sci U S A (2007) 2.37
ND10 components relocate to sites associated with herpes simplex virus type 1 nucleoprotein complexes during virus infection. J Virol (2005) 2.36
Daxx and histone deacetylase II associate with chromatin through an interaction with core histones and the chromatin-associated protein Dek. J Cell Sci (2002) 2.30
Specific histone tail modification and not DNA methylation is a determinant of herpes simplex virus type 1 latent gene expression. J Virol (2004) 2.25
Localization of a putative transcriptional regulator (ATRX) at pericentromeric heterochromatin and the short arms of acrocentric chromosomes. Proc Natl Acad Sci U S A (1999) 2.24
The Pax3-FKHR oncoprotein is unresponsive to the Pax3-associated repressor hDaxx. EMBO J (1999) 2.13
A viral activator of gene expression functions via the ubiquitin-proteasome pathway. EMBO J (1998) 2.06
Phenotype of a herpes simplex virus type 1 mutant that fails to express immediate-early regulatory protein ICP0. J Virol (2004) 2.03
The mammalian heterochromatin protein 1 binds diverse nuclear proteins through a common motif that targets the chromoshadow domain. Biochem Biophys Res Commun (2005) 2.00
A novel transcription regulatory complex containing death domain-associated protein and the ATR-X syndrome protein. J Biol Chem (2004) 1.98
ICP0 is required for efficient reactivation of herpes simplex virus type 1 from neuronal latency. J Virol (2001) 1.96
Replication of ICP0-null mutant herpes simplex virus type 1 is restricted by both PML and Sp100. J Virol (2007) 1.95
EAP1/Daxx interacts with ETS1 and represses transcriptional activation of ETS1 target genes. Oncogene (2000) 1.93
ATRX encodes a novel member of the SNF2 family of proteins: mutations point to a common mechanism underlying the ATR-X syndrome. Hum Mol Genet (1996) 1.91
Herpes simplex virus ICP0 promotes both histone removal and acetylation on viral DNA during lytic infection. J Virol (2008) 1.88
Interaction between chromatin proteins MECP2 and ATRX is disrupted by mutations that cause inherited mental retardation. Proc Natl Acad Sci U S A (2007) 1.84
Functional interaction between the pp71 protein of human cytomegalovirus and the PML-interacting protein human Daxx. J Virol (2002) 1.83
New insights into the role of the subnuclear structure ND10 for viral infection. Biochim Biophys Acta (2008) 1.82
Daxx-mediated accumulation of human cytomegalovirus tegument protein pp71 at ND10 facilitates initiation of viral infection at these nuclear domains. J Virol (2002) 1.81
Quiescent viral genomes in human fibroblasts after infection with herpes simplex virus type 1 Vmw65 mutants. J Gen Virol (1995) 1.78
A RING finger ubiquitin ligase is protected from autocatalyzed ubiquitination and degradation by binding to ubiquitin-specific protease USP7. J Biol Chem (2004) 1.76
Repression of gene expression upon infection of cells with herpes simplex virus type 1 mutants impaired for immediate-early protein synthesis. J Virol (1997) 1.70
Herpes simplex virus genes involved in latency in vitro. J Gen Virol (1987) 1.69
Temporal association of the herpes simplex virus genome with histone proteins during a lytic infection. J Virol (2007) 1.66
Herpes simplex virus type 1 genomes are associated with ND10 nuclear substructures in quiescently infected human fibroblasts. J Virol (2007) 1.65
Human Daxx-mediated repression of human cytomegalovirus gene expression correlates with a repressive chromatin structure around the major immediate early promoter. J Biol Chem (2006) 1.64
Heterochromatin and ND10 are cell-cycle regulated and phosphorylation-dependent alternate nuclear sites of the transcription repressor Daxx and SWI/SNF protein ATRX. J Cell Sci (2004) 1.63
ATRX, a member of the SNF2 family of helicase/ATPases, is required for chromosome alignment and meiotic spindle organization in metaphase II stage mouse oocytes. Dev Biol (2004) 1.60
Interphase-specific association of intrinsic centromere protein CENP-C with HDaxx, a death domain-binding protein implicated in Fas-mediated cell death. J Cell Sci (1998) 1.59
Functional interaction between class II histone deacetylases and ICP0 of herpes simplex virus type 1. J Virol (2004) 1.59
Human cytomegalovirus (HCMV) UL82 gene product (pp71) relieves hDaxx-mediated repression of HCMV replication. J Virol (2006) 1.55
Role of the cellular protein hDaxx in human cytomegalovirus immediate-early gene expression. J Gen Virol (2006) 1.52
Proteasome-dependent, ubiquitin-independent degradation of Daxx by the viral pp71 protein in human cytomegalovirus-infected cells. Virology (2007) 1.48
Analysis of the functions of herpes simplex virus type 1 regulatory protein ICP0 that are critical for lytic infection and derepression of quiescent viral genomes. J Virol (2009) 1.48
PML residue lysine 160 is required for the degradation of PML induced by herpes simplex virus type 1 regulatory protein ICP0. J Virol (2003) 1.46
Structural consequences of disease-causing mutations in the ATRX-DNMT3-DNMT3L (ADD) domain of the chromatin-associated protein ATRX. Proc Natl Acad Sci U S A (2007) 1.45
RNAi reveals anti-apoptotic and transcriptionally repressive activities of DAXX. J Cell Sci (2003) 1.43
The two functions of herpes simplex virus 1 ICP0, inhibition of silencing by the CoREST/REST/HDAC complex and degradation of PML, are executed in tandem. J Virol (2008) 1.40
Interaction between the human cytomegalovirus UL82 gene product (pp71) and hDaxx regulates immediate-early gene expression and viral replication. J Virol (2005) 1.39
Human cytomegalovirus protein pp71 displaces the chromatin-associated factor ATRX from nuclear domain 10 at early stages of infection. J Virol (2008) 1.36
SUMO modification negatively modulates the transcriptional activity of CREB-binding protein via the recruitment of Daxx. Proc Natl Acad Sci U S A (2005) 1.33
The cycle of human herpes simplex virus infection: virus transport and immune control. J Infect Dis (2006) 1.31
Negative modulation of androgen receptor transcriptional activity by Daxx. Mol Cell Biol (2004) 1.26
Homeodomain-interacting protein kinase 1 modulates Daxx localization, phosphorylation, and transcriptional activity. Mol Cell Biol (2003) 1.25
Evidence that the herpes simplex virus type 1 ICP0 protein does not initiate reactivation from latency in vivo. J Virol (2006) 1.24
Differential role of Sp100 isoforms in interferon-mediated repression of herpes simplex virus type 1 immediate-early protein expression. J Virol (2006) 1.24
Modification of nuclear PML protein by SUMO-1 regulates Fas-induced apoptosis in rheumatoid arthritis synovial fibroblasts. Proc Natl Acad Sci U S A (2007) 1.22
Daxx represses RelB target promoters via DNA methyltransferase recruitment and DNA hypermethylation. Genes Dev (2008) 1.21
Towards an understanding of the molecular basis of herpes simplex virus latency. Virus Res (2005) 1.21
Human cytomegalovirus tegument protein pp71 directs long-term gene expression from quiescent herpes simplex virus genomes. J Virol (2005) 1.15
SUMO-mediated inhibition of glucocorticoid receptor synergistic activity depends on stable assembly at the promoter but not on DAXX. Mol Endocrinol (2008) 1.12
Histone deacetylase inhibitors induce caspase-dependent apoptosis and downregulation of daxx in acute promyelocytic leukaemia with t(15;17). Br J Haematol (2001) 1.12
Relaxed repression of herpes simplex virus type 1 genomes in Murine trigeminal neurons. J Virol (2007) 1.08
Components of nuclear domain 10 bodies regulate varicella-zoster virus replication. J Virol (2009) 1.07
A suppressive role of the prolyl isomerase Pin1 in cellular apoptosis mediated by the death-associated protein Daxx. J Biol Chem (2007) 1.06
Visualization by live-cell microscopy of disruption of ND10 during herpes simplex virus type 1 infection. J Virol (2004) 1.06
Daxx is required for stress-induced cell death and JNK activation. Cell Death Differ (2005) 1.04
Modification of Daxx by small ubiquitin-related modifier-1. Biochem Biophys Res Commun (2002) 1.03
Association of ATRX with pericentric heterochromatin and the Y chromosome of neonatal mouse spermatogonia. BMC Mol Biol (2008) 1.02
Daxx mediates SUMO-dependent transcriptional control and subnuclear compartmentalization. Biochem Soc Trans (2007) 1.02
Promyelocytic leukemia-nuclear body proteins: herpesvirus enemies, accomplices, or both? Future Virol (2008) 0.98
Regulation of c-met expression by transcription repressor Daxx. Oncogene (2007) 0.98
Reactivation of expression from quiescent herpes simplex virus type 1 genomes in the absence of immediate-early protein ICP0. J Virol (2007) 0.94
Herpes simplex virus type 1 immediate-early protein ICP0 and is isolated RING finger domain act as ubiquitin E3 ligases in vitro. J Virol (2002) 4.06
The herpes simplex virus ICP0 RING finger domain inhibits IRF3- and IRF7-mediated activation of interferon-stimulated genes. J Virol (2004) 2.32
Regulation of alphaherpesvirus infections by the ICP0 family of proteins. J Gen Virol (2012) 1.76
A RING finger ubiquitin ligase is protected from autocatalyzed ubiquitination and degradation by binding to ubiquitin-specific protease USP7. J Biol Chem (2004) 1.76
A viral E3 ligase targets RNF8 and RNF168 to control histone ubiquitination and DNA damage responses. EMBO J (2010) 1.75
The herpes simplex virus type 1 (HSV-1) regulatory protein ICP0 interacts with and Ubiquitinates p53. J Biol Chem (2003) 1.58
Visualization of parental HSV-1 genomes and replication compartments in association with ND10 in live infected cells. EMBO J (2002) 1.57
Reciprocal activities between herpes simplex virus type 1 regulatory protein ICP0, a ubiquitin E3 ligase, and ubiquitin-specific protease USP7. J Virol (2005) 1.54
A viral ubiquitin ligase has substrate preferential SUMO targeted ubiquitin ligase activity that counteracts intrinsic antiviral defence. PLoS Pathog (2011) 1.47
PML residue lysine 160 is required for the degradation of PML induced by herpes simplex virus type 1 regulatory protein ICP0. J Virol (2003) 1.46
The intrinsic antiviral defense to incoming HSV-1 genomes includes specific DNA repair proteins and is counteracted by the viral protein ICP0. PLoS Pathog (2011) 1.37
Human cytomegalovirus protein pp71 displaces the chromatin-associated factor ATRX from nuclear domain 10 at early stages of infection. J Virol (2008) 1.36
PML isoforms I and II participate in PML-dependent restriction of HSV-1 replication. J Cell Sci (2010) 1.35
SUMO pathway dependent recruitment of cellular repressors to herpes simplex virus type 1 genomes. PLoS Pathog (2011) 1.30
Proteasome-dependent degradation of Daxx by the viral E1B-55K protein in human adenovirus-infected cells. J Virol (2010) 1.23
Components of promyelocytic leukemia nuclear bodies (ND10) act cooperatively to repress herpesvirus infection. J Virol (2012) 1.16
Herpes simplex virus 1 ubiquitin ligase ICP0 interacts with PML isoform I and induces its SUMO-independent degradation. J Virol (2012) 1.16
The viral ubiquitin ligase ICP0 is neither sufficient nor necessary for degradation of the cellular DNA sensor IFI16 during herpes simplex virus 1 infection. J Virol (2013) 1.14
Herpes simplex virus type 1 induces CD83 degradation in mature dendritic cells with immediate-early kinetics via the cellular proteasome. J Virol (2007) 1.03
Herpes simplex virus type 1 infection induces the stabilization of p53 in a USP7- and ATM-independent manner. J Virol (2004) 1.02
Control of human adenovirus type 5 gene expression by cellular Daxx/ATRX chromatin-associated complexes. Nucleic Acids Res (2013) 0.93
The homeodomain-interacting kinase PKM (HIPK-2) modifies ND10 through both its kinase domain and a SUMO-1 interaction motif and alters the posttranslational modification of PML. Exp Cell Res (2003) 0.86
Expression of herpes simplex virus 1 microRNAs in cell culture models of quiescent and latent infection. J Virol (2013) 0.86
Proteomic analysis of cells in the early stages of herpes simplex virus type-1 infection reveals widespread changes in the host cell proteome. Proteomics (2009) 0.84
PML isoforms in response to arsenic: high-resolution analysis of PML body structure and degradation. J Cell Sci (2013) 0.83
Herpes simplex virus type 1 ICP0 localizes in the stromal layer of infected rabbit corneas and resides predominantly in the cytoplasm and/or perinuclear region of rabbit keratocytes. J Gen Virol (2006) 0.81