Published in Biol Cell on November 01, 2008
Role of ABL family kinases in cancer: from leukaemia to solid tumours. Nat Rev Cancer (2013) 1.92
Structural basis for regulation of the Crk signaling protein by a proline switch. Nat Chem Biol (2010) 1.30
Abl kinases are required for invadopodia formation and chemokine-induced invasion. J Biol Chem (2010) 1.20
Arg/Abl2 promotes invasion and attenuates proliferation of breast cancer in vivo. Oncogene (2012) 1.20
Molecular basis of signaling specificity of insulin and IGF receptors: neglected corners and recent advances. Front Endocrinol (Lausanne) (2012) 1.17
c-Abl and Arg are activated in human primary melanomas, promote melanoma cell invasion via distinct pathways, and drive metastatic progression. Oncogene (2011) 1.15
Abl regulates smooth muscle cell proliferation by modulating actin dynamics and ERK1/2 activation. Am J Physiol Cell Physiol (2012) 1.07
Abl interconnects oncogenic Met and p53 core pathways in cancer cells. Cell Death Differ (2011) 1.05
Identification of markers of prostate cancer progression using candidate gene expression. Br J Cancer (2011) 1.04
The Hippo pathway kinase Lats2 prevents DNA damage-induced apoptosis through inhibition of the tyrosine kinase c-Abl. Cell Death Differ (2013) 1.04
Cdo binds Abl to promote p38alpha/beta mitogen-activated protein kinase activity and myogenic differentiation. Mol Cell Biol (2009) 1.03
The Roles of Glutathione Peroxidases during Embryo Development. Front Mol Neurosci (2011) 1.03
Dynamin 2 and c-Abl are novel regulators of hyperoxia-mediated NADPH oxidase activation and reactive oxygen species production in caveolin-enriched microdomains of the endothelium. J Biol Chem (2009) 1.02
Tyrosine-phosphorylated galectin-3 protein is resistant to prostate-specific antigen (PSA) cleavage. J Biol Chem (2012) 0.96
Reciprocal regulation of Abl and receptor tyrosine kinases. Cell Signal (2009) 0.93
Clinical targeting of mutated and wild-type protein tyrosine kinases in cancer. Mol Cell Biol (2014) 0.92
Biphenotypic, bilineal, ambiguous or mixed lineage: strange leukemias! Haematologica (2009) 0.91
Abl family tyrosine kinases regulate sialylated ganglioside receptors for polyomavirus. J Virol (2010) 0.88
STI571 sensitizes breast cancer cells to 5-fluorouracil, cisplatin and camptothecin in a cell type-specific manner. Biochem Pharmacol (2009) 0.88
Oncogenic tyrosine kinases target Dok-1 for ubiquitin-mediated proteasomal degradation to promote cell transformation. Mol Cell Biol (2011) 0.87
Intestine-specific transcription factor Cdx2 induces E-cadherin function by enhancing the trafficking of E-cadherin to the cell membrane. Am J Physiol Gastrointest Liver Physiol (2010) 0.86
High CC chemokine receptor 7 expression improves postoperative prognosis of lung adenocarcinoma patients. Br J Cancer (2013) 0.85
Peroxiredoxin 1 is a tumor-associated antigen in esophageal squamous cell carcinoma. Oncol Rep (2013) 0.83
Multifunctional Abl kinases in health and disease. J Cell Sci (2016) 0.83
Differential and opposing effects of imatinib on LPS- and ventilator-induced lung injury. Am J Physiol Lung Cell Mol Physiol (2014) 0.82
ABL tyrosine kinase inhibition variable effects on the invasive properties of different triple negative breast cancer cell lines. PLoS One (2015) 0.82
The Emerging Role of ABL Kinases in Solid Tumors. Trends Cancer (2015) 0.81
Selective targeting of c-Abl via a cryptic mitochondrial targeting signal activated by cellular redox status in leukemic and breast cancer cells. Pharm Res (2012) 0.80
c-Abl-p38α signaling plays an important role in MPTP-induced neuronal death. Cell Death Differ (2015) 0.80
Defying c-Abl signaling circuits through small allosteric compounds. Front Genet (2014) 0.79
Met acts through Abl to regulate p53 transcriptional outcomes and cell survival in the developing liver. J Hepatol (2012) 0.79
c-Abl inhibition delays motor neuron degeneration in the G93A mouse, an animal model of amyotrophic lateral sclerosis. PLoS One (2012) 0.79
Sphingosine-1-phosphate mediates a reciprocal signaling pathway between stellate cells and cancer cells that promotes pancreatic cancer growth. Am J Pathol (2014) 0.78
Abelson family tyrosine kinases regulate the function of nicotinic acetylcholine receptors and nicotinic synapses on autonomic neurons. Mol Pharmacol (2011) 0.78
Role of zinc metallothionein-3 (ZnMt3) in epidermal growth factor (EGF)-induced c-Abl protein activation and actin polymerization in cultured astrocytes. J Biol Chem (2011) 0.78
c-Abl modulates tumor cell sensitivity to antibody-dependent cellular cytotoxicity. Cancer Immunol Res (2014) 0.78
Cyclophilin A promotes cell migration via the Abl-Crk signaling pathway. Nat Chem Biol (2015) 0.77
Reduced miR-3127-5p expression promotes NSCLC proliferation/invasion and contributes to dasatinib sensitivity via the c-Abl/Ras/ERK pathway. Sci Rep (2014) 0.77
Molecular characterization of c-Abl/c-Src kinase inhibitors targeted against murine tumour progenitor cells that express stem cell markers. PLoS One (2010) 0.77
Saitohin, which is nested within the tau gene, interacts with tau and Abl and its human-specific allele influences Abl phosphorylation. J Cell Biochem (2011) 0.76
Structure-guided optimization of small molecule c-Abl activators. J Comput Aided Mol Des (2014) 0.76
c-Abl Kinase Is a Regulator of αvβ3 Integrin Mediated Melanoma A375 Cell Migration. PLoS One (2013) 0.76
Growth factor dependent regulation of centrosome function and genomic instability by HuR. Biomolecules (2015) 0.76
Delineation of key regulatory elements identifies points of vulnerability in the mitogen-activated signaling network. Genome Res (2011) 0.75
ABL2 suppresses FLT3-ITD-induced cell proliferation through negative regulation of AKT signaling. Oncotarget (2017) 0.75
Blockade of Y177 and Nuclear Translocation of Bcr-Abl Inhibits Proliferation and Promotes Apoptosis in Chronic Myeloid Leukemia Cells. Int J Mol Sci (2017) 0.75
How do kinases contribute to tonicity-dependent regulation of the transcription factor NFAT5? World J Nephrol (2016) 0.75
Coordination of signalling networks and tumorigenic properties by ABL in glioblastoma cells. Oncotarget (2016) 0.75
The LATS1 and LATS2 tumor suppressors: beyond the Hippo pathway. Cell Death Differ (2017) 0.75
SOCS1 function in BCR-ABL mediated myeloproliferative disease is dependent on the cytokine environment. PLoS One (2017) 0.75
Evidence that resistance to nilotinib may be due to BCR-ABL, Pgp, or Src kinase overexpression. Cancer Res (2008) 1.56
A function for phosphoinositide 3-kinase beta lipid products in coupling beta gamma to Ras activation in response to lysophosphatidic acid. J Biol Chem (2002) 1.49
c-Abl is an effector of Src for growth factor-induced c-myc expression and DNA synthesis. EMBO J (2002) 1.41
Quantitative phosphoproteomics reveals a cluster of tyrosine kinases that mediates SRC invasive activity in advanced colon carcinoma cells. Cancer Res (2009) 1.25
Nucleophosmin-anaplastic lymphoma kinase of anaplastic large-cell lymphoma recruits, activates, and uses pp60c-src to mediate its mitogenicity. Blood (2003) 1.22
Two distinct pools of Src family tyrosine kinases regulate PDGF-induced DNA synthesis and actin dorsal ruffles. J Cell Sci (2006) 1.11
Quantitative phosphoproteomics revealed interplay between Syk and Lyn in the resistance to nilotinib in chronic myeloid leukemia cells. Blood (2011) 1.11
Abl tyrosine kinase regulates a Rac/JNK and a Rac/Nox pathway for DNA synthesis and Myc expression induced by growth factors. J Cell Sci (2005) 1.09
The adaptor protein Tom1L1 is a negative regulator of Src mitogenic signaling induced by growth factors. Mol Cell Biol (2006) 1.07
Adherens junctions and tight junctions are regulated via different pathways by progastrin in epithelial cells. J Cell Sci (2003) 1.07
The transmembrane protein CBP plays a role in transiently anchoring small clusters of Thy-1, a GPI-anchored protein, to the cytoskeleton. J Cell Sci (2009) 1.00
Cloning of a novel phosphotyrosine binding domain containing molecule, Odin, involved in signaling by receptor tyrosine kinases. Oncogene (2002) 1.00
The Tom1L1-clathrin heavy chain complex regulates membrane partitioning of the tyrosine kinase Src required for mitogenic and transforming activities. Mol Cell Biol (2007) 0.92
A non-catalytic function of the Src family tyrosine kinases controls prolactin-induced Jak2 signaling. Cell Signal (2010) 0.92
Specific oncogenic activity of the Src-family tyrosine kinase c-Yes in colon carcinoma cells. PLoS One (2011) 0.90
Oncogenic signaling by tyrosine kinases of the SRC family in advanced colorectal cancer. Am J Cancer Res (2012) 0.89
The Csk-binding protein PAG regulates PDGF-induced Src mitogenic signaling via GM1. J Cell Biol (2008) 0.86
Cyclin E and cyclin A are likely targets of Src for PDGF-induced DNA synthesis in fibroblasts. FEBS Lett (2002) 0.85
Analysis of SRC oncogenic signaling in colorectal cancer by stable isotope labeling with heavy amino acids in mouse xenografts. Mol Cell Proteomics (2012) 0.82
Contribution of phosphoproteomics in understanding SRC signaling in normal and tumor cells. Proteomics (2015) 0.80