Extracellular ATP and zinc are co-secreted with insulin and activate multiple P2X purinergic receptor channels expressed by islet beta-cells to potentiate insulin secretion.

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Published in Purinergic Signal on October 23, 2008

Authors

Clintoria Richards-Williams1, Juan L Contreras, Kathleen H Berecek, Erik M Schwiebert

Author Affiliations

1: Department of Physiology and Biophysics, University of Alabama at Birmingham, 1918 University Blvd., Birmingham, AL, 35294-0005, USA.

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