Published in Curr Biol on October 30, 2008
The evolution of sex: a perspective from the fungal kingdom. Microbiol Mol Biol Rev (2010) 2.24
The complete sequence of the smallest known nuclear genome from the microsporidian Encephalitozoon intestinalis. Nat Commun (2010) 1.75
The dynamic roles of intracellular lipid droplets: from archaea to mammals. Protoplasma (2011) 1.66
Microsporidian genome analysis reveals evolutionary strategies for obligate intracellular growth. Genome Res (2012) 1.65
Evolution of eukaryotic microbial pathogens via covert sexual reproduction. Cell Host Microbe (2010) 1.50
Phylogenomics supports microsporidia as the earliest diverging clade of sequenced fungi. BMC Biol (2012) 1.45
Five-year cohort study of Nosema spp. in Germany: does climate shape virulence and assertiveness of Nosema ceranae? Appl Environ Microbiol (2010) 1.44
Five questions about microsporidia. PLoS Pathog (2009) 1.35
A glimpse into the basis of vision in the kingdom Mycota. Fungal Genet Biol (2010) 1.32
Phylogenomic analyses predict sistergroup relationship of nucleariids and fungi and paraphyly of zygomycetes with significant support. BMC Evol Biol (2009) 1.31
Sporangiospore size dimorphism is linked to virulence of Mucor circinelloides. PLoS Pathog (2011) 1.26
Evolution of the sex-related locus and genomic features shared in microsporidia and fungi. PLoS One (2010) 1.23
Chronic microsporidial enteritis in a missionary from Mozambique. Am J Trop Med Hyg (2010) 1.18
Draft genome sequence of the Daphnia pathogen Octosporea bayeri: insights into the gene content of a large microsporidian genome and a model for host-parasite interactions. Genome Biol (2009) 1.16
The genome of the obligate intracellular parasite Trachipleistophora hominis: new insights into microsporidian genome dynamics and reductive evolution. PLoS Pathog (2012) 1.16
A consistent phylogenetic backbone for the fungi. Mol Biol Evol (2011) 1.11
Conserved meiotic machinery in Glomus spp., a putatively ancient asexual fungal lineage. Genome Biol Evol (2011) 1.08
Non-lytic, actin-based exit of intracellular parasites from C. elegans intestinal cells. PLoS Pathog (2011) 1.05
Structure, function, and phylogeny of the mating locus in the Rhizopus oryzae complex. PLoS One (2010) 1.02
Analysis of a food-borne fungal pathogen outbreak: virulence and genome of a Mucor circinelloides isolate from yogurt. MBio (2014) 1.01
Tracing the origin of the fungal α1 domain places its ancestor in the HMG-box superfamily: implication for fungal mating-type evolution. PLoS One (2010) 0.98
Origins of eukaryotic sexual reproduction. Cold Spring Harb Perspect Biol (2014) 0.96
A network of HMG-box transcription factors regulates sexual cycle in the fungus Podospora anserina. PLoS Genet (2013) 0.92
Importance of nonenteric protozoan infections in immunocompromised people. Clin Microbiol Rev (2010) 0.92
Contrasting host-pathogen interactions and genome evolution in two generalist and specialist microsporidian pathogens of mosquitoes. Nat Commun (2015) 0.92
Evidence for maintenance of sex determinants but not of sexual stages in red yeasts, a group of early diverged basidiomycetes. BMC Evol Biol (2011) 0.92
Extremely reduced levels of heterozygosity in the vertebrate pathogen Encephalitozoon cuniculi. Eukaryot Cell (2013) 0.91
The cryptic sexual strategies of human fungal pathogens. Nat Rev Microbiol (2014) 0.91
Treatment of microsporidia keratitis with topical voriconazole monotherapy. Arch Ophthalmol (2011) 0.90
Sex determination in the first-described sexual fungus. Eukaryot Cell (2011) 0.88
Sex and speciation: the paradox that non-recombining DNA promotes recombination. Fungal Biol Rev (2011) 0.87
Interactions of Encephalitozoon cuniculi polar tube proteins. Infect Immun (2010) 0.87
A multigene phylogeny of Olpidium and its implications for early fungal evolution. BMC Evol Biol (2011) 0.87
Zygomycetes, microsporidia, and the evolutionary ancestry of sex determination. Genome Biol Evol (2011) 0.86
Update on mucormycosis pathogenesis. Curr Opin Infect Dis (2013) 0.86
The ancient function of RB-E2F pathway: insights from its evolutionary history. Biol Direct (2010) 0.86
Generation of genetic diversity in microsporidia via sexual reproduction and horizontal gene transfer. Commun Integr Biol (2009) 0.85
Exploiting the architecture and the features of the microsporidian genomes to investigate diversity and impact of these parasites on ecosystems. Heredity (Edinb) (2014) 0.84
Utilization of zebrafish for intravital study of eukaryotic pathogen-host interactions. Dev Comp Immunol (2014) 0.82
Effect of three drugs against Encephalitozoon cuniculi infection in immunosuppressed mice. Antimicrob Agents Chemother (2013) 0.81
Microsporidia: Horizontal gene transfers in vicious parasites. Mob Genet Elements (2011) 0.81
Mating type gene homologues and putative sex pheromone-sensing pathway in arbuscular mycorrhizal fungi, a presumably asexual plant root symbiont. PLoS One (2013) 0.80
Hematogenously disseminated skin disease caused by Mucor velutinosus in a patient with acute myeloid leukemia. J Clin Microbiol (2011) 0.80
Population Genetics of Nosema apis and Nosema ceranae: One Host (Apis mellifera) and Two Different Histories. PLoS One (2015) 0.79
Clonal Evolution of Enterocytozoon bieneusi Populations in Swine and Genetic Differentiation in Subpopulations between Isolates from Swine and Humans. PLoS Negl Trop Dis (2016) 0.78
The genome of an Encephalitozoon cuniculi type III strain reveals insights into the genetic diversity and mode of reproduction of a ubiquitous vertebrate pathogen. Heredity (Edinb) (2016) 0.78
Analysis of the protein domain and domain architecture content in fungi and its application in the search of new antifungal targets. PLoS Comput Biol (2014) 0.78
Evolution of sexual reproduction: a view from the Fungal Kingdom supports an evolutionary epoch with sex before sexes. Fungal Biol Rev (2015) 0.77
Sex in the Mucoralean fungi. Mycoses (2014) 0.77
Parallels in intercellular communication in oomycete and fungal pathogens of plants and humans. PLoS Pathog (2012) 0.77
Germination of phagocytosed E. cuniculi spores does not significantly contribute to parasitophorous vacuole formation in J774 cells. Parasitol Res (2010) 0.76
Should Y stay or should Y go: the evolution of non-recombining sex chromosomes. Bioessays (2012) 0.76
Unseen sex in ancient virgin fungi. New Phytol (2014) 0.75
Identification of candidate agents active against N. ceranae infection in honey bees: establishment of a medium throughput screening assay based on N. ceranae infected cultured cells. PLoS One (2015) 0.75
A new vesicular compartment in Encephalitozoon cuniculi. Microbes Infect (2011) 0.75
The evolution of organellar metabolism in unicellular eukaryotes. Philos Trans R Soc Lond B Biol Sci (2010) 0.75
The state of research for AIDS-associated opportunistic infections and the importance of sustaining smaller research communities. Eukaryot Cell (2011) 0.75
Microsporidial spores can cross the intact Descemet membrane in deep stromal infection. Middle East Afr J Ophthalmol (2013) 0.75
Genotype diversity in the honey bee parasite Nosema ceranae: multi-strain isolates, cryptic sex or both? BMC Evol Biol (2016) 0.75
Microsporidia: Obligate Intracellular Pathogens Within the Fungal Kingdom. Microbiol Spectr (2017) 0.75
Zinc PVA versus potassium dichromate for preservation of microsporidian spores of human origin. Parasitol Res (2012) 0.75
Improved tools for biological sequence comparison. Proc Natl Acad Sci U S A (1988) 193.60
Reconstructing the early evolution of Fungi using a six-gene phylogeny. Nature (2006) 8.94
Genome sequence and gene compaction of the eukaryote parasite Encephalitozoon cuniculi. Nature (2001) 7.53
Ribosomal RNA sequence suggests microsporidia are extremely ancient eukaryotes. Nature (1987) 4.40
A mitochondrial remnant in the microsporidian Trachipleistophora hominis. Nature (2002) 2.98
Microsporidiosis: current status. Curr Opin Infect Dis (2006) 2.81
Microsporidia are related to Fungi: evidence from the largest subunit of RNA polymerase II and other proteins. Proc Natl Acad Sci U S A (1999) 2.72
Microsporidia: biology and evolution of highly reduced intracellular parasites. Annu Rev Microbiol (2002) 2.56
Localization and functionality of microsporidian iron-sulphur cluster assembly proteins. Nature (2008) 1.84
Alpha-tubulin from early-diverging eukaryotic lineages and the evolution of the tubulin family. Mol Biol Evol (1996) 1.83
Evidence from beta-tubulin phylogeny that microsporidia evolved from within the fungi. Mol Biol Evol (2000) 1.78
Identification of the sex genes in an early diverged fungus. Nature (2008) 1.75
An expanded inventory of conserved meiotic genes provides evidence for sex in Trichomonas vaginalis. PLoS One (2007) 1.67
A novel route for ATP acquisition by the remnant mitochondria of Encephalitozoon cuniculi. Nature (2008) 1.66
Fish microsporidia: fine structural diversity and phylogeny. Int J Parasitol (2003) 1.62
Phylogenetic analysis of the complete genome sequence of Encephalitozoon cuniculi supports the fungal origin of microsporidia and reveals a high frequency of fast-evolving genes. J Mol Evol (2004) 1.60
Congruent evidence from alpha-tubulin and beta-tubulin gene phylogenies for a zygomycete origin of microsporidia. Fungal Genet Biol (2003) 1.54
Structure of a complex of tandem HMG boxes and DNA. J Mol Biol (2006) 1.51
Phylogenetic analysis of beta-tubulin sequences from amitochondrial protozoa. Mol Phylogenet Evol (1996) 1.48
Assessing the microsporidia-fungi relationship: Combined phylogenetic analysis of eight genes. Gene (2006) 1.29
Genome compaction and stability in microsporidian intracellular parasites. Curr Biol (2004) 1.28
The microsporidian polar tube: a highly specialised invasion organelle. Int J Parasitol (2005) 1.28
Patterns of genome evolution among the microsporidian parasites Encephalitozoon cuniculi, Antonospora locustae and Enterocytozoon bieneusi. PLoS One (2007) 1.16
Distinct localization patterns of two putative mitochondrial proteins in the microsporidian Encephalitozoon cuniculi. J Eukaryot Microbiol (2008) 1.02
Fungal mating-type loci. Curr Biol (2003) 1.01
Multiple losses of sex within a single genus of Microsporidia. BMC Evol Biol (2007) 0.98
Evolutionary biology: genomic clues to original sex in fungi. Curr Biol (2008) 0.92
The homeobox genes of Encephalitozoon cuniculi (Microsporidia) reveal a putative mating-type locus. Dev Genes Evol (2002) 0.87
Life cycle of Amblyospora dyxenoides sp. nov. in the mosquito Culex annulirostris and the copepod Mesocyclops albicans. J Invertebr Pathol (1988) 0.83
A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes. Nucleic Acids Res (2003) 7.56
Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs. Nat Genet (2006) 6.30
Evolution of pathogenicity and sexual reproduction in eight Candida genomes. Nature (2009) 5.90
Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a model eukaryote. PLoS Biol (2006) 5.44
Same-sex mating and the origin of the Vancouver Island Cryptococcus gattii outbreak. Nature (2005) 5.11
The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes. Science (2012) 4.93
The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans. Science (2005) 4.74
Sexual cycle of Cryptococcus neoformans var. grubii and virulence of congenic a and alpha isolates. Infect Immun (2003) 3.61
A PCR-based strategy to generate integrative targeting alleles with large regions of homology. Microbiology (2002) 3.58
Genome sequencing and comparative analysis of Saccharomyces cerevisiae strain YJM789. Proc Natl Acad Sci U S A (2007) 3.52
Computational and experimental identification of novel human imprinted genes. Genome Res (2007) 3.50
Recapitulation of the sexual cycle of the primary fungal pathogen Cryptococcus neoformans var. gattii: implications for an outbreak on Vancouver Island, Canada. Eukaryot Cell (2003) 3.25
Sexual reproduction between partners of the same mating type in Cryptococcus neoformans. Nature (2005) 3.22
Galleria mellonella as a model system to study Cryptococcus neoformans pathogenesis. Infect Immun (2005) 3.13
Mating-type locus of Cryptococcus neoformans: a step in the evolution of sex chromosomes. Eukaryot Cell (2002) 3.12
Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii. Genome Biol (2003) 3.03
Calcineurin is essential for survival during membrane stress in Candida albicans. EMBO J (2002) 2.81
Mapping of transcription start sites in Saccharomyces cerevisiae using 5' SAGE. Nucleic Acids Res (2005) 2.81
The human fungal pathogen Cryptococcus can complete its sexual cycle during a pathogenic association with plants. Cell Host Microbe (2007) 2.75
Emergence and pathogenicity of highly virulent Cryptococcus gattii genotypes in the northwest United States. PLoS Pathog (2010) 2.67
Deciphering the model pathogenic fungus Cryptococcus neoformans. Nat Rev Microbiol (2005) 2.63
Harnessing calcineurin as a novel anti-infective agent against invasive fungal infections. Nat Rev Microbiol (2007) 2.60
The cyclophilins. Genome Biol (2005) 2.58
Genetics of Cryptococcus neoformans. Annu Rev Genet (2002) 2.57
Hsp90 orchestrates temperature-dependent Candida albicans morphogenesis via Ras1-PKA signaling. Curr Biol (2009) 2.50
A common red algal origin of the apicomplexan, dinoflagellate, and heterokont plastids. Proc Natl Acad Sci U S A (2010) 2.41
Molecular evidence that the range of the Vancouver Island outbreak of Cryptococcus gattii infection has expanded into the Pacific Northwest in the United States. J Infect Dis (2009) 2.37
Calcineurin controls growth, morphology, and pathogenicity in Aspergillus fumigatus. Eukaryot Cell (2006) 2.35
The biology of the Cryptococcus neoformans species complex. Annu Rev Microbiol (2006) 2.31
Renaming the DSCR1/Adapt78 gene family as RCAN: regulators of calcineurin. FASEB J (2007) 2.30
Insights into evolution of multicellular fungi from the assembled chromosomes of the mushroom Coprinopsis cinerea (Coprinus cinereus). Proc Natl Acad Sci U S A (2010) 2.30
Killing of Caenorhabditis elegans by Cryptococcus neoformans as a model of yeast pathogenesis. Proc Natl Acad Sci U S A (2002) 2.29
Cryptococcal cell morphology affects host cell interactions and pathogenicity. PLoS Pathog (2010) 2.28
Mechanistic plasticity of sexual reproduction and meiosis in the Candida pathogenic species complex. Curr Biol (2009) 2.25
The evolution of sex: a perspective from the fungal kingdom. Microbiol Mol Biol Rev (2010) 2.24
Convergent evolution of chromosomal sex-determining regions in the animal and fungal kingdoms. PLoS Biol (2004) 2.22
Adenylyl cyclase functions downstream of the Galpha protein Gpa1 and controls mating and pathogenicity of Cryptococcus neoformans. Eukaryot Cell (2002) 2.21
Spread of Cryptococcus gattii into Pacific Northwest region of the United States. Emerg Infect Dis (2009) 2.19
Genetic diversity and host plant preferences revealed by simple sequence repeat and mitochondrial markers in a population of the arbuscular mycorrhizal fungus Glomus intraradices. New Phytol (2008) 2.16
Algal genomes reveal evolutionary mosaicism and the fate of nucleomorphs. Nature (2012) 2.15
Light controls growth and development via a conserved pathway in the fungal kingdom. PLoS Biol (2005) 2.15
Specialization of the HOG pathway and its impact on differentiation and virulence of Cryptococcus neoformans. Mol Biol Cell (2005) 2.12
The evolutionary history of haptophytes and cryptophytes: phylogenomic evidence for separate origins. Proc Biol Sci (2012) 2.12
Sensing the environment: lessons from fungi. Nat Rev Microbiol (2007) 2.10
The complete chloroplast genome of the chlorarachniophyte Bigelowiella natans: evidence for independent origins of chlorarachniophyte and euglenid secondary endosymbionts. Mol Biol Evol (2006) 1.99
Calcineurin is essential for Candida albicans survival in serum and virulence. Eukaryot Cell (2003) 1.98
Contribution of horizontal gene transfer to the evolution of Saccharomyces cerevisiae. Eukaryot Cell (2005) 1.95
Genome structure of a Saccharomyces cerevisiae strain widely used in bioethanol production. Genome Res (2009) 1.94
Genome of an arbuscular mycorrhizal fungus provides insight into the oldest plant symbiosis. Proc Natl Acad Sci U S A (2013) 1.94
Large-scale phylogenomic analyses reveal that two enigmatic protist lineages, telonemia and centroheliozoa, are related to photosynthetic chromalveolates. Genome Biol Evol (2009) 1.89
Cryptococcus neoformans gene expression during murine macrophage infection. Eukaryot Cell (2005) 1.89
Unisexual and heterosexual meiotic reproduction generate aneuploidy and phenotypic diversity de novo in the yeast Cryptococcus neoformans. PLoS Biol (2013) 1.88
Lateral gene transfer and the evolution of plastid-targeted proteins in the secondary plastid-containing alga Bigelowiella natans. Proc Natl Acad Sci U S A (2003) 1.87
A unique fungal two-component system regulates stress responses, drug sensitivity, sexual development, and virulence of Cryptococcus neoformans. Mol Biol Cell (2006) 1.86
Cell biology. Irremediable complexity? Science (2010) 1.85
Protein kinase A operates a molecular switch that governs yeast pseudohyphal differentiation. Mol Cell Biol (2002) 1.84
CBOL protist working group: barcoding eukaryotic richness beyond the animal, plant, and fungal kingdoms. PLoS Biol (2012) 1.84
The Cryptococcus neoformans MAP kinase Mpk1 regulates cell integrity in response to antifungal drugs and loss of calcineurin function. Mol Microbiol (2003) 1.81
Ergosterol biosynthesis inhibitors become fungicidal when combined with calcineurin inhibitors against Candida albicans, Candida glabrata, and Candida krusei. Antimicrob Agents Chemother (2003) 1.80
Cryptococcus neoformans in organ transplant recipients: impact of calcineurin-inhibitor agents on mortality. J Infect Dis (2007) 1.78
The complete sequence of the smallest known nuclear genome from the microsporidian Encephalitozoon intestinalis. Nat Commun (2010) 1.75
Enzymes that counteract nitrosative stress promote fungal virulence. Curr Biol (2003) 1.75
Transcriptional network of multiple capsule and melanin genes governed by the Cryptococcus neoformans cyclic AMP cascade. Eukaryot Cell (2005) 1.75
Identification of the sex genes in an early diverged fungus. Nature (2008) 1.75
Shared signatures of parasitism and phylogenomics unite Cryptomycota and microsporidia. Curr Biol (2013) 1.73
Genomic survey of the non-cultivatable opportunistic human pathogen, Enterocytozoon bieneusi. PLoS Pathog (2009) 1.73
Evidence that plant-like genes in Chlamydia species reflect an ancestral relationship between Chlamydiaceae, cyanobacteria, and the chloroplast. Genome Res (2002) 1.72
Spores as infectious propagules of Cryptococcus neoformans. Infect Immun (2009) 1.72
Evolution of fungal sex chromosomes. Mol Microbiol (2004) 1.71
Evidence of sexual recombination among Cryptococcus neoformans serotype A isolates in sub-Saharan Africa. Eukaryot Cell (2003) 1.71
First contemporary case of human infection with Cryptococcus gattii in Puget Sound: evidence for spread of the Vancouver Island outbreak. J Clin Microbiol (2007) 1.70
Complete nucleotide sequence of the chlorarachniophyte nucleomorph: nature's smallest nucleus. Proc Natl Acad Sci U S A (2006) 1.70
Identification and characterization of upstream open reading frames (uORF) in the 5' untranslated regions (UTR) of genes in Saccharomyces cerevisiae. Curr Genet (2005) 1.70
The reacquisition of biotin prototrophy in Saccharomyces cerevisiae involved horizontal gene transfer, gene duplication and gene clustering. Genetics (2007) 1.69
The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) (2014) 1.68
Cryptococcus neoformans virulence gene discovery through insertional mutagenesis. Eukaryot Cell (2004) 1.68
A constitutively active GPCR governs morphogenic transitions in Cryptococcus neoformans. EMBO J (2009) 1.68
Cell identity and sexual development in Cryptococcus neoformans are controlled by the mating-type-specific homeodomain protein Sxi1alpha. Genes Dev (2002) 1.68
Calcineurin: a central controller of signalling in eukaryotes. EMBO Rep (2004) 1.65
Good fungi gone bad: the corruption of calcineurin. Bioessays (2002) 1.64
Global distribution of a wild alga revealed by targeted metagenomics. Curr Biol (2012) 1.64
Sex and virulence of human pathogenic fungi. Adv Genet (2007) 1.63
Comparative genomic analysis of fungal genomes reveals intron-rich ancestors. Genome Biol (2007) 1.63
Carbonic anhydrase and CO2 sensing during Cryptococcus neoformans growth, differentiation, and virulence. Curr Biol (2005) 1.62
Synergistic effect of calcineurin inhibitors and fluconazole against Candida albicans biofilms. Antimicrob Agents Chemother (2008) 1.62
Coping with stress: calmodulin and calcineurin in model and pathogenic fungi. Biochem Biophys Res Commun (2003) 1.61
Novel gene functions required for melanization of the human pathogen Cryptococcus neoformans. Mol Microbiol (2005) 1.59
Adenylyl cyclase-associated protein Aca1 regulates virulence and differentiation of Cryptococcus neoformans via the cyclic AMP-protein kinase A cascade. Eukaryot Cell (2004) 1.59
On the monophyly of chromalveolates using a six-protein phylogeny of eukaryotes. Int J Syst Evol Microbiol (2005) 1.56
A MAP kinase cascade composed of cell type specific and non-specific elements controls mating and differentiation of the fungal pathogen Cryptococcus neoformans. Mol Microbiol (2003) 1.55
Mating-type-specific and nonspecific PAK kinases play shared and divergent roles in Cryptococcus neoformans. Eukaryot Cell (2002) 1.55
Comparative genome analysis of Trichophyton rubrum and related dermatophytes reveals candidate genes involved in infection. MBio (2012) 1.55
Calcineurin inhibition or mutation enhances cell wall inhibitors against Aspergillus fumigatus. Antimicrob Agents Chemother (2007) 1.54
Identification of Cryptococcus neoformans temperature-regulated genes with a genomic-DNA microarray. Eukaryot Cell (2004) 1.54