Published in Infect Immun on September 01, 2003
Recapitulation of the sexual cycle of the primary fungal pathogen Cryptococcus neoformans var. gattii: implications for an outbreak on Vancouver Island, Canada. Eukaryot Cell (2003) 3.25
Galleria mellonella as a model system to study Cryptococcus neoformans pathogenesis. Infect Immun (2005) 3.13
Cryptococcal cell morphology affects host cell interactions and pathogenicity. PLoS Pathog (2010) 2.28
The evolution of sex: a perspective from the fungal kingdom. Microbiol Mol Biol Rev (2010) 2.24
Multilocus sequence typing reveals three genetic subpopulations of Cryptococcus neoformans var. grubii (serotype A), including a unique population in Botswana. Genetics (2005) 2.16
Evidence of a role for monocytes in dissemination and brain invasion by Cryptococcus neoformans. Infect Immun (2008) 2.15
Light controls growth and development via a conserved pathway in the fungal kingdom. PLoS Biol (2005) 2.15
Specialization of the HOG pathway and its impact on differentiation and virulence of Cryptococcus neoformans. Mol Biol Cell (2005) 2.12
Unisexual and heterosexual meiotic reproduction generate aneuploidy and phenotypic diversity de novo in the yeast Cryptococcus neoformans. PLoS Biol (2013) 1.88
A unique fungal two-component system regulates stress responses, drug sensitivity, sexual development, and virulence of Cryptococcus neoformans. Mol Biol Cell (2006) 1.86
Chitosan, the deacetylated form of chitin, is necessary for cell wall integrity in Cryptococcus neoformans. Eukaryot Cell (2007) 1.76
Spores as infectious propagules of Cryptococcus neoformans. Infect Immun (2009) 1.72
Evidence of sexual recombination among Cryptococcus neoformans serotype A isolates in sub-Saharan Africa. Eukaryot Cell (2003) 1.71
A constitutively active GPCR governs morphogenic transitions in Cryptococcus neoformans. EMBO J (2009) 1.68
Cryptococcus neoformans virulence gene discovery through insertional mutagenesis. Eukaryot Cell (2004) 1.68
Low genetic variation and no detectable population structure in aspergillus fumigatus compared to closely related Neosartorya species. Eukaryot Cell (2006) 1.67
Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation. PLoS Genet (2014) 1.62
Adenylyl cyclase-associated protein Aca1 regulates virulence and differentiation of Cryptococcus neoformans via the cyclic AMP-protein kinase A cascade. Eukaryot Cell (2004) 1.59
Exploiting amoeboid and non-vertebrate animal model systems to study the virulence of human pathogenic fungi. PLoS Pathog (2007) 1.55
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Cryptococcus neoformans senses CO2 through the carbonic anhydrase Can2 and the adenylyl cyclase Cac1. Eukaryot Cell (2006) 1.41
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PKC1 is essential for protection against both oxidative and nitrosative stresses, cell integrity, and normal manifestation of virulence factors in the pathogenic fungus Cryptococcus neoformans. Eukaryot Cell (2008) 1.39
A diverse population of Cryptococcus gattii molecular type VGIII in southern Californian HIV/AIDS patients. PLoS Pathog (2011) 1.38
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Cryptococcus neoformans {alpha} strains preferentially disseminate to the central nervous system during coinfection. Infect Immun (2005) 1.33
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A genetic linkage map of Cryptococcus neoformans variety neoformans serotype D (Filobasidiella neoformans). Genetics (2004) 1.32
Transcription factor Nrg1 mediates capsule formation, stress response, and pathogenesis in Cryptococcus neoformans. Eukaryot Cell (2006) 1.32
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Transcription factors Mat2 and Znf2 operate cellular circuits orchestrating opposite- and same-sex mating in Cryptococcus neoformans. PLoS Genet (2010) 1.28
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Septins enforce morphogenetic events during sexual reproduction and contribute to virulence of Cryptococcus neoformans. Mol Microbiol (2009) 1.25
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The Cryptococcus neoformans catalase gene family and its role in antioxidant defense. Eukaryot Cell (2006) 1.24
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Eca1, a sarcoplasmic/endoplasmic reticulum Ca2+-ATPase, is involved in stress tolerance and virulence in Cryptococcus neoformans. Infect Immun (2007) 1.17
UGD1, encoding the Cryptococcus neoformans UDP-glucose dehydrogenase, is essential for growth at 37 degrees C and for capsule biosynthesis. Eukaryot Cell (2004) 1.16
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Unique evolution of the UPR pathway with a novel bZIP transcription factor, Hxl1, for controlling pathogenicity of Cryptococcus neoformans. PLoS Pathog (2011) 1.15
Cryptococcus neoformans gene involved in mammalian pathogenesis identified by a Caenorhabditis elegans progeny-based approach. Infect Immun (2005) 1.13
PAK kinases Ste20 and Pak1 govern cell polarity at different stages of mating in Cryptococcus neoformans. Mol Biol Cell (2004) 1.12
Ssk2 mitogen-activated protein kinase kinase kinase governs divergent patterns of the stress-activated Hog1 signaling pathway in Cryptococcus neoformans. Eukaryot Cell (2007) 1.11
Identification of ENA1 as a virulence gene of the human pathogenic fungus Cryptococcus neoformans through signature-tagged insertional mutagenesis. Eukaryot Cell (2009) 1.11
Many globally isolated AD hybrid strains of Cryptococcus neoformans originated in Africa. PLoS Pathog (2007) 1.10
Peroxisome function regulates growth on glucose in the basidiomycete fungus Cryptococcus neoformans. Eukaryot Cell (2006) 1.10
Interaction between genetic background and the mating-type locus in Cryptococcus neoformans virulence potential. Genetics (2005) 1.10
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Conserved elements of the RAM signaling pathway establish cell polarity in the basidiomycete Cryptococcus neoformans in a divergent fashion from other fungi. Mol Biol Cell (2006) 1.08
The mating type locus (MAT) and sexual reproduction of Cryptococcus heveanensis: insights into the evolution of sex and sex-determining chromosomal regions in fungi. PLoS Genet (2010) 1.08
Canonical heterotrimeric G proteins regulating mating and virulence of Cryptococcus neoformans. Mol Biol Cell (2007) 1.08
Titan cell production enhances the virulence of Cryptococcus neoformans. Infect Immun (2012) 1.07
Subcellular localization directs signaling specificity of the Cryptococcus neoformans Ras1 protein. Eukaryot Cell (2008) 1.07
Evidence that the human pathogenic fungus Cryptococcus neoformans var. grubii may have evolved in Africa. PLoS One (2011) 1.07
Cryptococcus neoformans mitochondrial genomes from serotype A and D strains do not influence virulence. Curr Genet (2004) 1.06
Profiling a killer, the development of Cryptococcus neoformans. FEMS Microbiol Rev (2011) 1.06
A tetrad analysis of the basidiomycete fungus Cryptococcus neoformans. Genetics (2010) 1.05
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The alpha-specific cell identity factor Sxi1alpha is not required for virulence of Cryptococcus neoformans. Infect Immun (2004) 1.04
The RGS protein Crg2 regulates both pheromone and cAMP signalling in Cryptococcus neoformans. Mol Microbiol (2008) 1.04
Ste50 adaptor protein governs sexual differentiation of Cryptococcus neoformans via the pheromone-response MAPK signaling pathway. Fungal Genet Biol (2010) 1.03
The Cryptococcus neoformans Rho-GDP dissociation inhibitor mediates intracellular survival and virulence. Infect Immun (2008) 1.03
Regulatory diversity of TUP1 in Cryptococcus neoformans. Eukaryot Cell (2009) 1.03
Transitions in sexuality: recapitulation of an ancestral tri- and tetrapolar mating system in Cryptococcus neoformans. Eukaryot Cell (2008) 1.02
Role of an expanded inositol transporter repertoire in Cryptococcus neoformans sexual reproduction and virulence. MBio (2010) 1.01
A Sch9 protein kinase homologue controlling virulence independently of the cAMP pathway in Cryptococcus neoformans. Curr Genet (2004) 1.00
Nitrogen metabolite repression of metabolism and virulence in the human fungal pathogen Cryptococcus neoformans. Genetics (2011) 1.00
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Calcineurin colocalizes with P-bodies and stress granules during thermal stress in Cryptococcus neoformans. Eukaryot Cell (2011) 0.97
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