Published in Circulation on November 04, 2008
A novel and efficient model of coronary artery ligation and myocardial infarction in the mouse. Circ Res (2010) 3.00
Profound cardioprotection with chloramphenicol succinate in the swine model of myocardial ischemia-reperfusion injury. Circulation (2010) 2.06
Inhibition of permeability transition pore opening by mitochondrial STAT3 and its role in myocardial ischemia/reperfusion. Basic Res Cardiol (2010) 1.88
Beta3-adrenoreceptor stimulation ameliorates myocardial ischemia-reperfusion injury via endothelial nitric oxide synthase and neuronal nitric oxide synthase activation. J Am Coll Cardiol (2011) 1.83
A novel role of microRNA in late preconditioning: upregulation of endothelial nitric oxide synthase and heat shock protein 70. Circ Res (2009) 1.69
Remote ischemic conditioning. J Am Coll Cardiol (2015) 1.66
New horizons in cardioprotection: recommendations from the 2010 National Heart, Lung, and Blood Institute Workshop. Circulation (2011) 1.66
Ischemia/reperfusion injury and cardioprotective mechanisms: Role of mitochondria and reactive oxygen species. World J Cardiol (2011) 1.51
TNFα in myocardial ischemia/reperfusion, remodeling and heart failure. Heart Fail Rev (2011) 1.47
Cardiovascular remodelling in coronary artery disease and heart failure. Lancet (2014) 1.47
MicroRNA-21 Mediates Isoflurane-induced Cardioprotection against Ischemia-Reperfusion Injury via Akt/Nitric Oxide Synthase/Mitochondrial Permeability Transition Pore Pathway. Anesthesiology (2015) 1.43
Translating novel strategies for cardioprotection: the Hatter Workshop Recommendations. Basic Res Cardiol (2010) 1.37
Cardiac hypertrophy is not amplified by deletion of cGMP-dependent protein kinase I in cardiomyocytes. Proc Natl Acad Sci U S A (2010) 1.33
Adiponectin: an indispensable molecule in rosiglitazone cardioprotection following myocardial infarction. Circ Res (2009) 1.16
Remote postconditioning by humoral factors in effluent from ischemic preconditioned rat hearts is mediated via PI3K/Akt-dependent cell-survival signaling at reperfusion. Basic Res Cardiol (2010) 1.15
Fractional flow reserve as a surrogate for inducible myocardial ischaemia. Nat Rev Cardiol (2013) 1.11
Retracted Connexin 43 acts as a cytoprotective mediator of signal transduction by stimulating mitochondrial KATP channels in mouse cardiomyocytes. J Clin Invest (2010) 1.10
EMMPRIN activates multiple transcription factors in cardiomyocytes, and induces interleukin-18 expression via Rac1-dependent PI3K/Akt/IKK/NF-kappaB andMKK7/JNK/AP-1 signaling. J Mol Cell Cardiol (2010) 1.05
Cyclosporine A at reperfusion reduces infarct size in pigs. Cardiovasc Drugs Ther (2010) 1.04
Therapeutic hypothermia cardioprotection via Akt- and nitric oxide-mediated attenuation of mitochondrial oxidants. Am J Physiol Heart Circ Physiol (2010) 1.03
Epigenetic modifications in cardiovascular disease. Basic Res Cardiol (2012) 1.02
Disrupting the EMMPRIN (CD147)-cyclophilin A interaction reduces infarct size and preserves systolic function after myocardial ischemia and reperfusion. Arterioscler Thromb Vasc Biol (2011) 1.02
STAT3 and cardiac remodeling. Heart Fail Rev (2011) 1.01
Mitochondrial connexin 43 impacts on respiratory complex I activity and mitochondrial oxygen consumption. J Cell Mol Med (2012) 1.01
The role of gasotransmitters NO, H2S and CO in myocardial ischaemia/reperfusion injury and cardioprotection by preconditioning, postconditioning and remote conditioning. Br J Pharmacol (2014) 1.01
Expression of active protein phosphatase 1 inhibitor-1 attenuates chronic beta-agonist-induced cardiac apoptosis. Basic Res Cardiol (2010) 1.00
Ischemic preconditioning attenuates mitochondrial localization of PTEN induced by ischemia-reperfusion. Am J Physiol Heart Circ Physiol (2011) 1.00
Secretome of apoptotic peripheral blood cells (APOSEC) confers cytoprotection to cardiomyocytes and inhibits tissue remodelling after acute myocardial infarction: a preclinical study. Basic Res Cardiol (2011) 0.99
Arginase regulates red blood cell nitric oxide synthase and export of cardioprotective nitric oxide bioactivity. Proc Natl Acad Sci U S A (2013) 0.98
Retracted Glycogen synthase kinase 3β transfers cytoprotective signaling through connexin 43 onto mitochondrial ATP-sensitive K+ channels. Proc Natl Acad Sci U S A (2012) 0.98
Cardioprotective effect of adiponectin is partially mediated by its AMPK-independent antinitrative action. Am J Physiol Endocrinol Metab (2009) 0.97
Catestatin improves post-ischemic left ventricular function and decreases ischemia/reperfusion injury in heart. Cell Mol Neurobiol (2010) 0.97
Endothelial-cardiomyocyte crosstalk enhances pharmacological cardioprotection. J Mol Cell Cardiol (2011) 0.96
The COX-2/PGI2 receptor axis plays an obligatory role in mediating the cardioprotection conferred by the late phase of ischemic preconditioning. PLoS One (2012) 0.96
The antiarrhythmic dipeptide ZP1609 (danegaptide) when given at reperfusion reduces myocardial infarct size in pigs. Naunyn Schmiedebergs Arch Pharmacol (2013) 0.96
bFGF attenuates endoplasmic reticulum stress and mitochondrial injury on myocardial ischaemia/reperfusion via activation of PI3K/Akt/ERK1/2 pathway. J Cell Mol Med (2014) 0.95
Stromal derived factor 1α: a chemokine that delivers a two-pronged defence of the myocardium. Pharmacol Ther (2014) 0.95
Upregulation of cardioprotective SUR2A by sub-hypoxic drop in oxygen. Biochim Biophys Acta (2014) 0.94
What makes the mitochondria a killer? Can we condition them to be less destructive? Biochim Biophys Acta (2010) 0.94
MicroRNAs in ischemia-reperfusion injury. Am J Cardiovasc Dis (2012) 0.94
Extracellular signalling molecules in the ischaemic/reperfused heart - druggable and translatable for cardioprotection? Br J Pharmacol (2014) 0.93
Ischemic preconditioning: the role of mitochondria and aging. Exp Gerontol (2011) 0.93
Identification of inducible nitric oxide synthase in peripheral blood cells as a mediator of myocardial ischemia/reperfusion injury. Basic Res Cardiol (2012) 0.93
Nitrite in organ protection. Br J Pharmacol (2014) 0.93
Inhibition of soluble epoxide hydrolase preserves cardiomyocytes: role of STAT3 signaling. Am J Physiol Heart Circ Physiol (2009) 0.92
A novel role for mitochondrial sphingosine-1-phosphate produced by sphingosine kinase-2 in PTP-mediated cell survival during cardioprotection. Basic Res Cardiol (2011) 0.91
Hematopoietic cytokines for cardiac repair: mobilization of bone marrow cells and beyond. Basic Res Cardiol (2011) 0.91
Constitutive phosphorylation of inhibitor-1 at Ser67 and Thr75 depresses calcium cycling in cardiomyocytes and leads to remodeling upon aging. Basic Res Cardiol (2012) 0.90
Evidence for an intracellular localization of the adenosine A2B receptor in rat cardiomyocytes. Basic Res Cardiol (2011) 0.90
Cardiomyocyte-restricted overexpression of extracellular superoxide dismutase increases nitric oxide bioavailability and reduces infarct size after ischemia/reperfusion. Basic Res Cardiol (2012) 0.90
Myocardial infarction differentially alters sphingolipid levels in plasma, erythrocytes and platelets of the rat. Basic Res Cardiol (2012) 0.89
Ischaemic conditioning: pitfalls on the path to clinical translation. Br J Pharmacol (2015) 0.89
Randomized phase 2 trial of intracoronary nitrite during acute myocardial infarction. Circ Res (2014) 0.89
Comparison Review of Short-Acting and Long-Acting Glucagon-like Peptide-1 Receptor Agonists. Diabetes Ther (2015) 0.88
Blockade of electron transport at the onset of reperfusion decreases cardiac injury in aged hearts by protecting the inner mitochondrial membrane. J Aging Res (2012) 0.88
Acute erythropoietin cardioprotection is mediated by endothelial response. Basic Res Cardiol (2011) 0.88
Cardioprotection by mild hypothermia during ischemia involves preservation of ERK activity. Basic Res Cardiol (2011) 0.87
Decreased tetrahydrobiopterin and disrupted association of Hsp90 with eNOS by hyperglycemia impair myocardial ischemic preconditioning. Am J Physiol Heart Circ Physiol (2011) 0.87
Clinical application of ischemic preconditioning in the elderly. Dose Response (2009) 0.87
HIF-1α signaling activation by post-ischemia treatment with astragaloside IV attenuates myocardial ischemia-reperfusion injury. PLoS One (2014) 0.87
Effect of repeated ischaemic preconditioning on TLR4 and proinflammatory cytokines TNF-α and IL-1β in myocardial ischaemia-reperfusion injury in a rat model. Arch Med Sci (2010) 0.85
Ischemic conditioning: the challenge of protecting the diabetic heart. Cardiovasc Diagn Ther (2014) 0.85
Secretome of apoptotic peripheral blood cells (APOSEC) attenuates microvascular obstruction in a porcine closed chest reperfused acute myocardial infarction model: role of platelet aggregation and vasodilation. Basic Res Cardiol (2012) 0.85
Gene transfer as a strategy to achieve permanent cardioprotection II: rAAV-mediated gene therapy with heme oxygenase-1 limits infarct size 1 year later without adverse functional consequences. Basic Res Cardiol (2011) 0.84
Gene transfer as a strategy to achieve permanent cardioprotection I: rAAV-mediated gene therapy with inducible nitric oxide synthase limits infarct size 1 year later without adverse functional consequences. Basic Res Cardiol (2011) 0.84
Remote conditioning the heart overview: translatability and mechanism. Br J Pharmacol (2014) 0.84
Neuronal nitric oxide synthase is indispensable for the cardiac adaptive effects of exercise. Basic Res Cardiol (2013) 0.84
Cardiac vulnerability to ischemia/reperfusion injury drastically increases in late pregnancy. Basic Res Cardiol (2012) 0.84
Long-term protection and mechanism of pacing-induced postconditioning in the heart. Basic Res Cardiol (2010) 0.83
Infarct size reduction by cyclosporine A at reperfusion involves inhibition of the mitochondrial permeability transition pore but does not improve mitochondrial respiration. Arch Med Sci (2013) 0.82
S-nitrosation of mitochondrial connexin 43 regulates mitochondrial function. Basic Res Cardiol (2014) 0.82
The cardioprotection granted by metoprolol is restricted to its administration prior to coronary reperfusion. Int J Cardiol (2009) 0.82
The alpha1 isoform of soluble guanylate cyclase regulates cardiac contractility but is not required for ischemic preconditioning. Basic Res Cardiol (2011) 0.82
Selective blockade of protein kinase B protects the rat and human myocardium against ischaemic injury. J Physiol (2010) 0.82
Ischemic preconditioning in the younger and aged heart. Aging Dis (2011) 0.82
Catestatin exerts direct protective effects on rat cardiomyocytes undergoing ischemia/reperfusion by stimulating PI3K-Akt-GSK3β pathway and preserving mitochondrial membrane potential. PLoS One (2015) 0.82
Post-ischemic early acidosis in cardiac postconditioning modifies the activity of antioxidant enzymes, reduces nitration, and favors protein S-nitrosylation. Pflugers Arch (2011) 0.82
Impairment of endothelial-myocardial interaction increases the susceptibility of cardiomyocytes to ischemia/reperfusion injury. PLoS One (2013) 0.82
Adjuvant cardioprotection in cardiac surgery: update. Biomed Res Int (2014) 0.81
Subcellular preconditioning of stem cells: mito-Cx43 gene targeting is cytoprotective via shift of mitochondrial Bak and Bcl-xL balance. Regen Med (2012) 0.81
Cardiomyocyte sulfonylurea receptor 2-KATP channel mediates cardioprotection and ST segment elevation. Am J Physiol Heart Circ Physiol (2010) 0.81
Effect of arginase inhibition on ischemia-reperfusion injury in patients with coronary artery disease with and without diabetes mellitus. PLoS One (2014) 0.81
Glycine, a simple physiological compound protecting by yet puzzling mechanism(s) against ischaemia-reperfusion injury: current knowledge. Br J Pharmacol (2012) 0.80
Sevoflurane Preconditioning Reduces Intestinal Ischemia-Reperfusion Injury: Role of Protein Kinase C and Mitochondrial ATP-Sensitive Potassium Channel. PLoS One (2015) 0.80
Correlation of plasma catestatin level and the prognosis of patients with acute myocardial infarction. PLoS One (2015) 0.80
BNP controls early load-dependent regulation of SERCA through calcineurin. Basic Res Cardiol (2010) 0.79
Cardioprotection by remote ischemic conditioning and its signal transduction. Pflugers Arch (2016) 0.78
β3-Adrenoreceptor stimulation protects against myocardial infarction injury via eNOS and nNOS activation. PLoS One (2014) 0.78
Concentration-dependent wrestling between detrimental and protective effects of H2O2 during myocardial ischemia/reperfusion. Cell Death Dis (2014) 0.78
Distinct cardioprotective mechanisms of immediate, early and delayed ischaemic postconditioning. Basic Res Cardiol (2014) 0.78
Activities of cardiac tissue matrix metalloproteinases 2 and 9 are reduced by remote ischemic preconditioning in cardiosurgical patients with cardiopulmonary bypass. J Transl Med (2014) 0.78
Cardioprotection: a review of current practice in global ischemia and future translational perspective. Biomed Res Int (2014) 0.78
Age-related reduction of cerebral ischemic preconditioning: myth or reality? Clin Interv Aging (2013) 0.78
Endoplasmic reticulum stress-dependent activation of ATF3 mediates the late phase of ischemic preconditioning. J Mol Cell Cardiol (2014) 0.77
Cardiac gene therapy: are we there yet? Gene Ther (2016) 0.77
Myocardial post-conditioning with Danshen-Gegen decoction protects against isoproterenol-induced myocardial injury via a PKCε/mKATP-mediated pathway in rats. Chin Med (2011) 0.77
Rapid ventricular pacing-induced postconditioning attenuates reperfusion injury: effects on peroxynitrite, RISK and SAFE pathways. Br J Pharmacol (2015) 0.77
Cardioprotective Effect of High Intensity Interval Training and Nitric Oxide Metabolites (NO2 (-), NO3 (-)). Iran J Public Health (2015) 0.77
Apoptosis-related protein expression in rabbits with blast brain injury following early hyperbaric oxygen therapy. Neural Regen Res (2012) 0.76
Cardiac myocyte-specific expression of inducible nitric oxide synthase protects against ischemia/reperfusion injury by preventing mitochondrial permeability transition. Circulation (2008) 2.37
Repetitive ischemia by coronary stenosis induces a novel window of ischemic preconditioning. Circulation (2008) 2.09
A cathepsin D-cleaved 16 kDa form of prolactin mediates postpartum cardiomyopathy. Cell (2007) 5.85
Cerebral embolization during transcatheter aortic valve implantation: a transcranial Doppler study. Circulation (2012) 3.70
Interaction of cardiovascular risk factors with myocardial ischemia/reperfusion injury, preconditioning, and postconditioning. Pharmacol Rev (2007) 3.19
Plasma nitrite reflects constitutive nitric oxide synthase activity in mammals. Free Radic Biol Med (2003) 2.83
High-density lipoproteins and their constituent, sphingosine-1-phosphate, directly protect the heart against ischemia/reperfusion injury in vivo via the S1P3 lysophospholipid receptor. Circulation (2006) 2.58
Signal transducer and activator of transcription 3 is required for myocardial capillary growth, control of interstitial matrix deposition, and heart protection from ischemic injury. Circ Res (2004) 2.45
Translocation of connexin 43 to the inner mitochondrial membrane of cardiomyocytes through the heat shock protein 90-dependent TOM pathway and its importance for cardioprotection. Circ Res (2006) 2.37
Red blood cells express a functional endothelial nitric oxide synthase. Blood (2005) 2.30
Running: the risk of coronary events : Prevalence and prognostic relevance of coronary atherosclerosis in marathon runners. Eur Heart J (2008) 2.28
ATP release from activated neutrophils occurs via connexin 43 and modulates adenosine-dependent endothelial cell function. Circ Res (2006) 2.23
Postconditioning and protection from reperfusion injury: where do we stand? Position paper from the Working Group of Cellular Biology of the Heart of the European Society of Cardiology. Cardiovasc Res (2010) 2.20
Myocardial late gadolinium enhancement: prevalence, pattern, and prognostic relevance in marathon runners. Radiology (2009) 2.05
TNFalpha in atherosclerosis, myocardial ischemia/reperfusion and heart failure. Pharmacol Ther (2010) 2.01
Loss of cardioprotection with ageing. Cardiovasc Res (2009) 1.94
Vascular pathophysiology in response to increased heart rate. J Am Coll Cardiol (2010) 1.88
Inhibition of permeability transition pore opening by mitochondrial STAT3 and its role in myocardial ischemia/reperfusion. Basic Res Cardiol (2010) 1.88
Oxidative modification of tropomyosin and myocardial dysfunction following coronary microembolization. Eur Heart J (2006) 1.87
Coronary microembolization: from bedside to bench and back to bedside. Circulation (2009) 1.85
Connexin 43 in cardiomyocyte mitochondria and its increase by ischemic preconditioning. Cardiovasc Res (2005) 1.75
Ischemic postconditioning in pigs: no causal role for RISK activation. Circ Res (2008) 1.74
The myocardial JAK/STAT pathway: from protection to failure. Pharmacol Ther (2008) 1.72
Translating cardioprotection for patient benefit: position paper from the Working Group of Cellular Biology of the Heart of the European Society of Cardiology. Cardiovasc Res (2013) 1.72
Nitric oxide in myocardial ischemia/reperfusion injury. Cardiovasc Res (2004) 1.69
Inhibition of mitochondrial permeability transition pore opening: the Holy Grail of cardioprotection. Basic Res Cardiol (2010) 1.66
New horizons in cardioprotection: recommendations from the 2010 National Heart, Lung, and Blood Institute Workshop. Circulation (2011) 1.66
Myocardial hibernation: a delicate balance. Am J Physiol Heart Circ Physiol (2004) 1.65
Cardioprotection by ischemic postconditioning is lost in aged and STAT3-deficient mice. Circ Res (2007) 1.64
Emerging importance of alpha-adrenergic coronary vasoconstriction in acute coronary syndromes and its genetic background. J Am Coll Cardiol (2003) 1.59
Microdialysis-based analysis of interstitial NO in situ: NO synthase-independent NO formation during myocardial ischemia. Cardiovasc Res (2007) 1.58
Remote ischemic preconditioning reduces myocardial injury after coronary artery bypass surgery with crystalloid cardioplegic arrest. Basic Res Cardiol (2010) 1.55
Prevention of the ischemia-induced decrease in mitochondrial Tom20 content by ischemic preconditioning. J Mol Cell Cardiol (2006) 1.53
Characterization of the GNAQ promoter and association of increased Gq expression with cardiac hypertrophy in humans. Eur Heart J (2008) 1.52
Ischemic preconditioning preserves connexin 43 phosphorylation during sustained ischemia in pig hearts in vivo. FASEB J (2003) 1.51
Bidirectional role of tumor necrosis factor-alpha in coronary microembolization: progressive contractile dysfunction versus delayed protection against infarction. Circ Res (2006) 1.50
Sphingosine-1-phosphate receptor 3 promotes recruitment of monocyte/macrophages in inflammation and atherosclerosis. Circ Res (2010) 1.50
Circulating nitrite contributes to cardioprotection by remote ischemic preconditioning. Circ Res (2014) 1.49
Confounders of Cardioprotection by Remote Ischemic Preconditioning in Patients Undergoing Coronary Artery Bypass Grafting. Cardiology (2015) 1.48
TNFα in myocardial ischemia/reperfusion, remodeling and heart failure. Heart Fail Rev (2011) 1.47
Left ventricular volumes and mass in marathon runners and their association with cardiovascular risk factors. Int J Cardiovasc Imaging (2008) 1.47
Differential expression of GAPDH and beta3-actin in growing collateral arteries. Mol Cell Biochem (2002) 1.45
Myocardial dysfunction with coronary microembolization: signal transduction through a sequence of nitric oxide, tumor necrosis factor-alpha, and sphingosine. Circ Res (2002) 1.45
The German CPU Registry: comparison of troponin positive to troponin negative patients. Int J Cardiol (2013) 1.43
Preparatory balloon aortic valvuloplasty during transcatheter aortic valve implantation for improved valve sizing. JACC Cardiovasc Interv (2013) 1.42
The Use of Echocardiography in Certified Chest Pain Units: Results from the German Chest Pain Unit Registry. Cardiology (2016) 1.41
The sphingosine-1-phosphate analogue FTY720 reduces atherosclerosis in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol (2006) 1.41
No ischemic preconditioning in heterozygous connexin43-deficient mice. Am J Physiol Heart Circ Physiol (2002) 1.38
Translating novel strategies for cardioprotection: the Hatter Workshop Recommendations. Basic Res Cardiol (2010) 1.37
Impairment of diazoxide-induced formation of reactive oxygen species and loss of cardioprotection in connexin 43 deficient mice. Circ Res (2005) 1.34
Coronary microembolization: the role of TNF-alpha in contractile dysfunction. J Mol Cell Cardiol (2002) 1.32
Ischemic postconditioning: experimental models and protocol algorithms. Basic Res Cardiol (2009) 1.27
[European National Society cardiovascular journals. Background, rationale and mission statement of the "editors' club"]. Rev Esp Cardiol (2008) 1.26
Improvement of regional myocardial blood flow and function and reduction of infarct size with ivabradine: protection beyond heart rate reduction. Eur Heart J (2008) 1.21
Sphingosine 1-phosphate levels in plasma and HDL are altered in coronary artery disease. Basic Res Cardiol (2010) 1.20
Presence of connexin 43 in subsarcolemmal, but not in interfibrillar cardiomyocyte mitochondria. Basic Res Cardiol (2009) 1.20
B-type natriuretic peptide limits infarct size in rat isolated hearts via KATP channel opening. Am J Physiol Heart Circ Physiol (2003) 1.19
Postconditioning: old wine in a new bottle? J Am Coll Cardiol (2004) 1.19
Survivin determines cardiac function by controlling total cardiomyocyte number. Circulation (2008) 1.18
Selective inhibition of Cx43 hemichannels by Gap19 and its impact on myocardial ischemia/reperfusion injury. Basic Res Cardiol (2012) 1.17
New insights into the S-nitrosothiol-ascorbate reaction. The formation of nitroxyl. Org Biomol Chem (2009) 1.14
Connexin43 in cardiomyocyte mitochondria contributes to mitochondrial potassium uptake. Cardiovasc Res (2009) 1.14