Published in Biochem J on September 15, 1991
The role of cellular hydration in the regulation of cell function. Biochem J (1996) 1.58
Liver cell volume and protein synthesis. Biochem J (1992) 1.10
Hyperosmolarity leads to an increase in derepressed system A activity in the renal epithelial cell line NBL-1. Biochem J (1993) 1.09
Inhibition of proteolysis by cell swelling in the liver requires intact microtubular structures. Biochem J (1995) 1.07
Cell hydration controls autophagosome formation in rat liver in a microtubule-dependent way downstream from p38MAPK activation. Biochem J (2001) 1.07
Regulation of cell volume in the perfused rat liver by hormones. Biochem J (1991) 1.07
In yeast, loss of Hog1 leads to osmosensitivity of autophagy. Biochem J (2006) 0.97
Nitric oxide inhibits glycogen synthesis in isolated rat hepatocytes. Biochem J (1998) 0.90
Cell shrinkage follows, rather than mediates, the short-term effects of glucagon on carbohydrate metabolism. Biochem J (1992) 0.87
VRACs and other ion channels and transporters in the regulation of cell volume and beyond. Nat Rev Mol Cell Biol (2016) 0.85
Endogenous hydroperoxide formation, cell volume and cellular K+ balance in perfused rat liver. Biochem J (1993) 0.85
Inhibition of autophagic proteolysis by cell swelling in hepatocytes. Biochem J (1995) 0.82
A chimerical phagocytosis model reveals the recruitment by Sertoli cells of autophagy for the degradation of ingested illegitimate substrates. Autophagy (2013) 0.81
Activation of hepatocyte growth factor by urokinase-type plasminogen activator is ionic strength-dependent. Biochem J (2005) 0.79
Hepatic glycogen can regulate hypoglycemic counterregulation via a liver-brain axis. J Clin Invest (2016) 0.76
Intracellular protein catabolism and its control during nutrient deprivation and supply. Annu Rev Nutr (1987) 3.03
Formation and metabolism of inositol 1,3,4,5-tetrakisphosphate in liver. J Biol Chem (1986) 2.81
The regulation of the matrix volume of mammalian mitochondria in vivo and in vitro and its role in the control of mitochondrial metabolism. Biochim Biophys Acta (1989) 2.70
Inhibition by insulin of valine turnover in liver. Evidence for a general control of proteolysis. J Biol Chem (1970) 2.54
Glucagon-induced autophagy and proteolysis in rat liver: mediation by selective deprivation of intracellular amino acids. Proc Natl Acad Sci U S A (1979) 2.54
Glucagon: a protein catabolic hormone in the isolated perfused rat liver. Nature (1960) 1.89
The use of perfusion of liver and other organs for the study of microsomal electron-transport and cytochrome P-450 systems. Methods Enzymol (1978) 1.86
The effect of ammonium chloride and glucagon on the metabolism of glutamine in isolated liver cells from starved rats. Biochim Biophys Acta (1978) 1.69
Swelling of rat hepatocytes stimulates glycogen synthesis. J Biol Chem (1990) 1.68
Amino acid control of autophagic sequestration and protein degradation in isolated rat hepatocytes. J Cell Biol (1984) 1.50
Water, K+, H+, lactate and glucose fluxes during cell volume regulation in perfused rat liver. Pflugers Arch (1989) 1.31
Cell swelling inhibits proteolysis in perfused rat liver. Biochem J (1990) 1.27
Interactions between glutamine metabolism and cell-volume regulation in perfused rat liver. Eur J Biochem (1990) 1.25
Protein degradation in hepatocyte monolayers. Effects of glucagon, adenosine 3':5'-cyclic monophosphate and insulin. Biochem J (1980) 1.18
Cell volume regulation in liver. Ren Physiol Biochem (1989) 1.15
The hormone-sensitive hepatic Na+-pump. Evidence for regulation by diacylglycerol and tumor promoters. J Biol Chem (1986) 1.09
Control of hepatic proteolysis by amino acids. The role of cell volume. Eur J Biochem (1991) 1.08
Cell volume regulatory responses of isolated perfused rat liver. The effect of amino acids. Biol Chem Hoppe Seyler (1990) 1.03
Control of hepatic nitrogen metabolism and glutathione release by cell volume regulatory mechanisms. Eur J Biochem (1990) 1.01
Increased activity of phosphate-dependent glutaminase in liver mitochondria as a result of glucagon treatment of rats. Biochem J (1981) 1.01
Volume regulation in liver: further characterization by inhibitors and ionic substitutions. Hepatology (1990) 1.00
Exposure of perfused liver to hypotonic conditions modifies cellular nitrogen metabolism. J Cell Biochem (1990) 0.94
Inhibition of hepatic proteolysis by insulin. Role of hormone-induced alterations of the cellular K+ balance. Eur J Biochem (1991) 0.89
The mutual interaction between cell volume and cell function: a new principle of metabolic regulation. Biochem Cell Biol (1991) 0.88
Vasopressin, insulin and peroxide(s) of vanadate (pervanadate) influence Na+ transport mediated by (Na+, K+)ATPase or Na+/H+ exchanger of rat liver plasma membrane vesicles. Eur J Biochem (1990) 0.84
Role of eicosanoids, inositol phosphates and extracellular Ca2+ in cell-volume regulation of rat liver. Eur J Biochem (1991) 0.82
Functional significance of cell volume regulatory mechanisms. Physiol Rev (1998) 4.59
Long-term survival in patients with hereditary hemochromatosis. Gastroenterology (1996) 4.00
Long-term follow-up of HBeAg-positive patients treated with interferon alfa for chronic hepatitis B. N Engl J Med (1996) 3.41
Prognosis of chronic hepatitis C: results of a large, prospective cohort study. Hepatology (1998) 3.00
The low-affinity monocarboxylate transporter MCT4 is adapted to the export of lactate in highly glycolytic cells. Biochem J (2000) 2.59
FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway. Immunity (1995) 2.19
Cloning and characterization of a putative human serine/threonine protein kinase transcriptionally modified during anisotonic and isotonic alterations of cell volume. Proc Natl Acad Sci U S A (1997) 2.14
Prior cytomegalovirus infection and the risk of restenosis after percutaneous transluminal coronary balloon angioplasty. Circulation (1999) 2.13
Mutations in GJB6 cause nonsyndromic autosomal dominant deafness at DFNA3 locus. Nat Genet (1999) 2.05
[Demonstration of HFE polymorphism in German patients with hereditary hemochromatosis]. Dtsch Med Wochenschr (1999) 2.03
Mitomycin C in combination with capecitabine or biweekly high-dose gemcitabine in patients with advanced biliary tract cancer: a randomised phase II trial. Ann Oncol (2004) 1.95
Cloning and characterization of two human polyspecific organic cation transporters. DNA Cell Biol (1997) 1.91
Regulation of the multidrug resistance protein 2 in the rat liver by lipopolysaccharide and dexamethasone. Gastroenterology (1999) 1.87
CD95/CD95 ligand interactions on epithelial cells in host defense to Pseudomonas aeruginosa. Science (2000) 1.77
Regulation of interleukin-6 expression in cultured human blood monocytes and monocyte-derived macrophages. Blood (1988) 1.76
Effects of cytokines on the liver. Hepatology (1991) 1.76
Synthesis of a muscarinic receptor antagonist via a diastereoselective Michael reaction, selective deoxyfluorination and aromatic metal-halogen exchange reaction. J Org Chem (2001) 1.75
Proton magnetic resonance spectroscopy of the brain in symptomatic and asymptomatic patients with liver cirrhosis. Gastroenterology (1997) 1.70
Evidence for a vasoconstriction-mediating receptor for UTP, distinct from the P2 purinoceptor, in rabbit ear artery. Naunyn Schmiedebergs Arch Pharmacol (1987) 1.68
Extracellular K+ and intracellular pH allosterically regulate renal Kir1.1 channels. J Biol Chem (1996) 1.68
Expression of the peripheral-type benzodiazepine receptor and apoptosis induction in hepatic stellate cells. Gastroenterology (2001) 1.66
Transjugular intrahepatic portosystemic stent-shunt (TIPS) in the treatment of Budd-Chiari syndrome. J Hepatol (1993) 1.63
Biweekly high-dose gemcitabine alone or in combination with capecitabine in patients with metastatic pancreatic adenocarcinoma: a randomized phase II trial. Ann Oncol (2003) 1.62
Repulsively bound atom pairs in an optical lattice. Nature (2006) 1.62
Hepatorenal reflex regulating kidney function. Hepatology (1991) 1.61
Function and structure of heterodimeric amino acid transporters. Am J Physiol Cell Physiol (2001) 1.60
Control of the levels of free amino acids in plasma by the liver. Biochem Z (1965) 1.54
CD66-mediated phagocytosis of Opa52 Neisseria gonorrhoeae requires a Src-like tyrosine kinase- and Rac1-dependent signalling pathway. EMBO J (1998) 1.53
Cell volume in the regulation of hepatic function: a mechanism for metabolic control. Biochim Biophys Acta (1991) 1.51
Fas- or ceramide-induced apoptosis is mediated by a Rac1-regulated activation of Jun N-terminal kinase/p38 kinases and GADD153. J Biol Chem (1997) 1.51
Plasmodium knowlesi infection imported to Germany, January 2013. Euro Surveill (2013) 1.50
Cortical origin of mini-asterixis in hepatic encephalopathy. Neurology (2002) 1.50
The astroglial ASCT2 amino acid transporter as a mediator of glutamine efflux. J Neurochem (1999) 1.50
Irinotecan plus raltitrexed vs raltitrexed alone in patients with gemcitabine-pretreated advanced pancreatic adenocarcinoma. Br J Cancer (2003) 1.48
Acidic sphingomyelinase mediates entry of N. gonorrhoeae into nonphagocytic cells. Cell (1997) 1.47
LPS and TNFalpha induce SOCS3 mRNA and inhibit IL-6-induced activation of STAT3 in macrophages. FEBS Lett (1999) 1.46
Anal endosonography and manometry: comparison in patients with defecation problems. Dis Colon Rectum (1997) 1.46
Role of N-linked glycosylation in rat renal Na/Pi-cotransport. J Biol Chem (1994) 1.46
Synaptic vesicles: selective depletion in crayfish excitatory and inhibitory axons. Science (1972) 1.44
Modulation of Neisseria porin (PorB) by cytosolic ATP/GTP of target cells: parallels between pathogen accommodation and mitochondrial endosymbiosis. Cell (1996) 1.44
Hepatocyte heterogeneity in glutamine and ammonia metabolism and the role of an intercellular glutamine cycle during ureogenesis in perfused rat liver. Eur J Biochem (1983) 1.43
Cardiotoxicity of the antiproliferative compound fluorouracil. Drugs (1999) 1.42
Second-line treatment of advanced gastric cancer with oxaliplatin plus raltitrexed. Onkologie (2003) 1.41
Actions of extracellular UTP and ATP in perfused rat liver. A comparative study. Eur J Biochem (1987) 1.40
Blockade of HERG channels expressed in Xenopus oocytes by the histamine receptor antagonists terfenadine and astemizole. FEBS Lett (1996) 1.40
Cellular hydration state: an important determinant of protein catabolism in health and disease. Lancet (1993) 1.38
The inhibitory effect of the antipsychotic drug haloperidol on HERG potassium channels expressed in Xenopus oocytes. Br J Pharmacol (1997) 1.38
Role of KCNE1-dependent K+ fluxes in mouse proximal tubule. J Am Soc Nephrol (2001) 1.38
Two consecutive phase II studies of 5-fluorouracil/leucovorin/mitomycin C and of gemcitabine in patients with advanced biliary cancer. Oncology (1999) 1.38
Evidence for a bicarbonate leak in the proximal tubule of the rat kidney. Pflugers Arch (1980) 1.36
Scintigraphic assessment of bowel involvement and disease activity in Crohn's disease using technetium 99m-hexamethyl propylene amine oxine as leukocyte label. Gastroenterology (1988) 1.35
Efficient detection and immunomagnetic sorting of specific T cells using multimers of MHC class I and peptide with reduced CD8 binding. Nat Med (2000) 1.33
Water, K+, H+, lactate and glucose fluxes during cell volume regulation in perfused rat liver. Pflugers Arch (1989) 1.31
Transport characteristics of a murine renal Na/Pi-cotransporter. Pflugers Arch (1995) 1.30
Electrophysiological characterization of the flounder type II Na+/Pi cotransporter (NaPi-5) expressed in Xenopus laevis oocytes. J Membr Biol (1997) 1.30
The tyrosine kinase p56lck mediates activation of swelling-induced chloride channels in lymphocytes. J Cell Biol (1998) 1.30
Ca2+-activated K channel of the BK-type in the inner mitochondrial membrane of a human glioma cell line. Biochem Biophys Res Commun (1999) 1.29
Characterization and natural course of cardiac autonomic nervous dysfunction in HIV-infected patients. AIDS (1997) 1.29
Response to interferon alfa is hepatitis B virus genotype dependent: genotype A is more sensitive to interferon than genotype D. Gut (2005) 1.28
h-sgk serine-threonine protein kinase gene as transcriptional target of transforming growth factor beta in human intestine. Gastroenterology (1999) 1.28
Cell swelling inhibits proteolysis in perfused rat liver. Biochem J (1990) 1.27
Proton magnetic resonance spectroscopy studies on human brain myo-inositol in hypo-osmolarity and hepatic encephalopathy. Gastroenterology (1994) 1.26
Interactions between glutamine metabolism and cell-volume regulation in perfused rat liver. Eur J Biochem (1990) 1.25
Influence of hydroxylation and conjugation of bile salts on their membrane-damaging properties--studies on isolated hepatocytes and lipid membrane vesicles. Hepatology (1984) 1.25
Inhibition of IKs in guinea pig cardiac myocytes and guinea pig IsK channels by the chromanol 293B. Pflugers Arch (1996) 1.24
Tyrosine phosphorylation-dependent suppression of a voltage-gated K+ channel in T lymphocytes upon Fas stimulation. J Biol Chem (1996) 1.23
Interference of H2O2 with stimulus-secretion coupling in mouse pancreatic beta-cells. J Physiol (1999) 1.23
Tyrosine kinase-dependent activation of a chloride channel in CD95-induced apoptosis in T lymphocytes. Proc Natl Acad Sci U S A (1998) 1.22
Functional hepatocyte heterogeneity in ammonia metabolism. The intercellular glutamine cycle. J Hepatol (1985) 1.22
Mutations of the core promoter and response to interferon treatment in chronic replicative hepatitis B. Hepatology (2000) 1.22
Activation of pyruvate dehydrogenase during metabolism of ammonium ions in hemoglobin-free perfused rat liver. Eur J Biochem (1975) 1.21
Human neurons express the polyspecific cation transporter hOCT2, which translocates monoamine neurotransmitters, amantadine, and memantine. Mol Pharmacol (1998) 1.21
L-selectin activates the Ras pathway via the tyrosine kinase p56lck. Proc Natl Acad Sci U S A (1996) 1.20
The heterodimeric amino acid transporter 4F2hc/y+LAT2 mediates arginine efflux in exchange with glutamine. Biochem J (2000) 1.20
Increased incidence of cancer in adult Gaucher disease in Western Europe. Blood Cells Mol Dis (2005) 1.19
Obligatory amino acid exchange via systems bo,+-like and y+L-like. A tertiary active transport mechanism for renal reabsorption of cystine and dibasic amino acids. J Biol Chem (1996) 1.19
Transjugular intrahepatic portacaval stent shunt: preliminary clinical results. Radiology (1990) 1.19
Regulation of cell function by the cellular hydration state. Am J Physiol (1994) 1.19
Neutral amino acid transporter ASCT2 displays substrate-induced Na+ exchange and a substrate-gated anion conductance. Biochem J (2000) 1.19
Electrophysiology of sodium-coupled transport in proximal renal tubules. Am J Physiol (1986) 1.18
Cation channels trigger apoptotic death of erythrocytes. Cell Death Differ (2003) 1.16
The use of Xenopus laevis oocytes for the functional characterization of heterologously expressed membrane proteins. Cell Physiol Biochem (2000) 1.16
Stimulation of CD95 (Fas) blocks T lymphocyte calcium channels through sphingomyelinase and sphingolipids. Proc Natl Acad Sci U S A (1999) 1.15
Cell volume regulation in liver. Ren Physiol Biochem (1989) 1.15
Spot-blot hybridization assay for the detection of hepatitis B virus DNA in serum: factors determining its sensitivity and specificity. Hepatology (1987) 1.15
Synthetic cascades are enabled by combining biocatalysts with artificial metalloenzymes. Nat Chem (2012) 1.14
Extra- and intracellular hydrogen ion-selective microelectrode based on neutral carriers with extended pH response range in acid media. Pflugers Arch (1988) 1.13
Regulation of interleukin 6 receptor expression in human monocytes and monocyte-derived macrophages. Comparison with the expression in human hepatocytes. J Exp Med (1989) 1.13
Regulation of flux through glutaminase and glutamine synthetase in isolated perfused rat liver. Biochim Biophys Acta (1983) 1.13
Evidence for electroneutral sodium chloride cotransport in the cortical thick ascending limb of Henle's loop of rabbit kidney. Pflugers Arch (1983) 1.13
A simple and rapid method for the detection of RNA in formalin-fixed, paraffin-embedded tissues by PCR amplification. Biochem Biophys Res Commun (1991) 1.12