Successful split liver-kidney transplant for factor H associated hemolytic uremic syndrome.

PubWeight™: 1.06‹?› | Rank: Top 15%

🔗 View Article (PMC 2615708)

Published in Clin J Am Soc Nephrol on November 12, 2008

Authors

Jeffrey M Saland1, Benjamin L Shneider, Jonathan S Bromberg, Patricia A Shi, Stephen C Ward, Margret S Magid, Corinne Benchimol, Mouin G Seikaly, Sukru H Emre, Elena Bresin, Giuseppe Remuzzi

Author Affiliations

1: Department of Pediatrics, The Mount Sinai Medical Center, One Gustave L Levy Place, New York, NY 10029, USA. Jeff.Saland@MSSM.EDU

Articles citing this

Relative role of genetic complement abnormalities in sporadic and familial aHUS and their impact on clinical phenotype. Clin J Am Soc Nephrol (2010) 3.82

Atypical hemolytic uremic syndrome. Orphanet J Rare Dis (2011) 3.35

aHUS caused by complement dysregulation: new therapies on the horizon. Pediatr Nephrol (2010) 1.67

Atypical hemolytic uremic syndrome. Semin Nephrol (2013) 1.56

Thrombotic microangiopathy and associated renal disorders. Nephrol Dial Transplant (2012) 1.44

New insights into postrenal transplant hemolytic uremic syndrome. Nat Rev Nephrol (2010) 1.36

Pre-emptive eculizumab and plasmapheresis for renal transplant in atypical hemolytic uremic syndrome. Clin J Am Soc Nephrol (2011) 1.29

Eculizumab induces long-term remission in recurrent post-transplant HUS associated with C3 gene mutation. Pediatr Nephrol (2010) 1.28

Hemolytic uremic syndrome. Semin Immunopathol (2014) 1.12

Liver-kidney transplantation to cure atypical HUS: still an option post-eculizumab? Pediatr Nephrol (2013) 0.92

Severe atypical HUS caused by CFH S1191L--case presentation and review of treatment options. Pediatr Nephrol (2009) 0.88

Complement disorders and hemolytic uremic syndrome. Curr Opin Pediatr (2013) 0.83

Review: Complement and its regulatory proteins in kidney diseases. Nephrology (Carlton) (2010) 0.82

Trombotic microangiopathy: can liver-kidney transplantation cure aHUS? Nat Rev Nephrol (2009) 0.76

Anesthetic management of living donor liver transplantation for complement factor H deficiency hemolytic uremic syndrome: a case report. Korean J Anesthesiol (2014) 0.75

The importance of genetic mutation screening to determine retransplantation following failed kidney allograft from recurrent atypical haemolytic ureamic syndrome. BMJ Case Rep (2014) 0.75

Guidelines for the management and investigation of hemolytic uremic syndrome. Clin Exp Nephrol (2014) 0.75

Articles cited by this

A simple estimate of glomerular filtration rate in children derived from body length and plasma creatinine. Pediatrics (1976) 13.83

Genetics of HUS: the impact of MCP, CFH, and IF mutations on clinical presentation, response to treatment, and outcome. Blood (2006) 4.51

Hemolytic uremic syndrome. J Am Soc Nephrol (2005) 3.19

New approaches to the treatment of dense deposit disease. J Am Soc Nephrol (2007) 3.02

Complement factor H mutations and gene polymorphisms in haemolytic uraemic syndrome: the C-257T, the A2089G and the G2881T polymorphisms are strongly associated with the disease. Hum Mol Genet (2003) 2.71

Complement factor I: a susceptibility gene for atypical haemolytic uraemic syndrome. J Med Genet (2004) 2.55

Combined kidney and liver transplantation for familial haemolytic uraemic syndrome. Lancet (2002) 2.12

Haemolytic uraemic syndrome and mutations of the factor H gene: a registry-based study of German speaking countries. J Med Genet (2003) 1.92

Implications of the initial mutations in membrane cofactor protein (MCP; CD46) leading to atypical hemolytic uremic syndrome. Mol Immunol (2006) 1.82

Spectrum of extrarenal involvement in postdiarrheal hemolytic-uremic syndrome. J Pediatr (1994) 1.72

Hypocomplementemia discloses genetic predisposition to hemolytic uremic syndrome and thrombotic thrombocytopenic purpura: role of factor H abnormalities. Italian Registry of Familial and Recurrent Hemolytic Uremic Syndrome/Thrombotic Thrombocytopenic Purpura. J Am Soc Nephrol (1999) 1.53

De novo gene conversion in the RCA gene cluster (1q32) causes mutations in complement factor H associated with atypical hemolytic uremic syndrome. Hum Mutat (2006) 1.46

Intravenous gamma globulin for thrombotic microangiopathy of unknown etiology. Pediatr Nephrol (2006) 1.43

Human complement factor H deficiency associated with hemolytic uremic syndrome. J Am Soc Nephrol (1998) 1.43

Characterization of mutations in complement factor I (CFI) associated with hemolytic uremic syndrome. Mol Immunol (2007) 1.42

Outcome of renal transplantation in patients with non-Shiga toxin-associated hemolytic uremic syndrome: prognostic significance of genetic background. Clin J Am Soc Nephrol (2005) 1.40

Favorable long-term outcome after liver-kidney transplant for recurrent hemolytic uremic syndrome associated with a factor H mutation. Am J Transplant (2006) 1.37

Hemolytic uremic syndrome: a fatal outcome after kidney and liver transplantation performed to correct factor h gene mutation. Am J Transplant (2005) 1.23

Successful plasma therapy for atypical hemolytic uremic syndrome caused by factor H deficiency owing to a novel mutation in the complement cofactor protein domain 15. Am J Kidney Dis (2005) 1.21

A mutation in factor I that is associated with atypical hemolytic uremic syndrome does not affect the function of factor I in complement regulation. Mol Immunol (2006) 1.15

Successful liver-kidney transplantation in two children with aHUS caused by a mutation in complement factor H. Am J Transplant (2007) 1.12

The risk of recurrence of hemolytic uremic syndrome after renal transplantation in children. Pediatr Nephrol (2003) 1.06

Successful (?) therapy of hemolytic-uremic syndrome with factor H abnormality. Pediatr Nephrol (2003) 1.06

High doses of intravenous Ig inhibit in vitro uptake of C4 fragments onto sensitized erythrocytes. Blood (1991) 1.02

Complement activation in patients with congestive heart failure: effect of high-dose intravenous immunoglobulin treatment. Circulation (2001) 1.01

Gastrointestinal complications of post-diarrheal hemolytic uremic syndrome. Eur J Pediatr Surg (2007) 1.00

A missense mutation in factor I (IF) predisposes to atypical haemolytic uraemic syndrome. Pediatr Nephrol (2006) 0.99

Familial relapsing haemolytic uraemic syndrome and complement factor H deficiency. Nephrol Dial Transplant (1999) 0.92

Membrane cofactor protein and factor I: mutations and transplantation. Semin Thromb Hemost (2006) 0.92

Cholestatic jaundice in the haemolytic-uraemic syndrome: a case report. Gut (1985) 0.91

Immunohistochemical demonstration of membrane cofactor protein (MCP) of complement in normal and diseased kidney tissues. Clin Exp Immunol (1993) 0.91

High-dose intravenous immunoglobulin treatment activates complement in vivo. Scand J Immunol (1998) 0.90

Complement activation after ischemia-reperfusion in human liver allografts: incidence and pathophysiological relevance. Gastroenterology (1997) 0.89

Recurrence of hemolytic-uremic syndrome in renal transplant recipients: a meta-analysis. Transplantation (1998) 0.88

Inhibition of complement-mediated haemolysis in paroxysmal nocturnal haemoglobinuria by heparin or low-molecular weight heparin. Br J Haematol (2000) 0.88

Recurrence of haemolytic-uraemic syndrome in renal transplants: a single-centre report. Nephrol Dial Transplant (1997) 0.88

Secondary failure of plasma therapy in factor H deficiency. Pediatr Nephrol (2006) 0.85

Treatment of thrombotic thrombocytopenic purpura with high-dose immunoglobulins. Results in 17 patients. Italian Cooperative Group for TTP. Haematologica (1995) 0.84

Complement membrane attack complex and hemodynamic changes during human orthotopic liver transplantation. Liver Transpl (2004) 0.83

Thrombotic thrombocytopenic purpura treated with high-dose intravenous gamma globulin. South Med J (1990) 0.81

Thrombotic microangiopathy and intravenous immunoglobulin therapy. Pediatr Nephrol (2007) 0.77

Infarction of the choledochus, liver, gallbladder, and pancreas: a unique complication of the hemolytic uremic syndrome. J Pediatr Surg (2000) 0.77

Articles by these authors

A trial of darbepoetin alfa in type 2 diabetes and chronic kidney disease. N Engl J Med (2009) 14.13

Rosuvastatin and cardiovascular events in patients undergoing hemodialysis. N Engl J Med (2009) 12.73

Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet (2015) 7.99

Selective vitamin D receptor activation with paricalcitol for reduction of albuminuria in patients with type 2 diabetes (VITAL study): a randomised controlled trial. Lancet (2010) 7.69

Bardoxolone methyl in type 2 diabetes and stage 4 chronic kidney disease. N Engl J Med (2013) 7.54

Preventing microalbuminuria in type 2 diabetes. N Engl J Med (2004) 6.41

The contribution of chronic kidney disease to the global burden of major noncommunicable diseases. Kidney Int (2011) 6.21

Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013: quantifying the epidemiological transition. Lancet (2015) 6.13

Atypical hemolytic-uremic syndrome. N Engl J Med (2009) 5.66

Erythropoietic response and outcomes in kidney disease and type 2 diabetes. N Engl J Med (2010) 5.48

Lower estimated glomerular filtration rate and higher albuminuria are associated with mortality and end-stage renal disease. A collaborative meta-analysis of kidney disease population cohorts. Kidney Int (2011) 5.25

Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts. Nat Immunol (2006) 5.00

Proteinuria, a target for renoprotection in patients with type 2 diabetic nephropathy: lessons from RENAAL. Kidney Int (2004) 4.51

Genetics of HUS: the impact of MCP, CFH, and IF mutations on clinical presentation, response to treatment, and outcome. Blood (2006) 4.51

Relative role of genetic complement abnormalities in sporadic and familial aHUS and their impact on clinical phenotype. Clin J Am Soc Nephrol (2010) 3.82

Rituximab in idiopathic membranous nephropathy. J Am Soc Nephrol (2012) 3.79

Albuminuria, a therapeutic target for cardiovascular protection in type 2 diabetic patients with nephropathy. Circulation (2004) 3.78

Blood-pressure control for renoprotection in patients with non-diabetic chronic renal disease (REIN-2): multicentre, randomised controlled trial. Lancet (2005) 3.52

How does proteinuria cause progressive renal damage? J Am Soc Nephrol (2006) 3.46

Mesenchymal stem cells are renotropic, helping to repair the kidney and improve function in acute renal failure. J Am Soc Nephrol (2004) 3.41

Regulatory T cells sequentially migrate from inflamed tissues to draining lymph nodes to suppress the alloimmune response. Immunity (2009) 3.32

Thrombomodulin mutations in atypical hemolytic-uremic syndrome. N Engl J Med (2009) 3.24

Hemolytic uremic syndrome. J Am Soc Nephrol (2005) 3.19

Early-childhood membranous nephropathy due to cationic bovine serum albumin. N Engl J Med (2011) 3.17

TGF-beta induces Foxp3 + T-regulatory cells from CD4 + CD25 - precursors. Am J Transplant (2004) 3.15

Sodium intake, ACE inhibition, and progression to ESRD. J Am Soc Nephrol (2011) 3.13

Delayed graft function in kidney transplantation. Lancet (2004) 3.06

Acute liver failure in children: the first 348 patients in the pediatric acute liver failure study group. J Pediatr (2006) 3.03

Mutations in factor H reduce binding affinity to C3b and heparin and surface attachment to endothelial cells in hemolytic uremic syndrome. J Clin Invest (2003) 2.96

Decision time for pancreatic islet-cell transplantation. Lancet (2008) 2.91

Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation. J Immunol (2009) 2.87

Familial haemolytic uraemic syndrome and an MCP mutation. Lancet (2003) 2.79

Complement factor H mutations and gene polymorphisms in haemolytic uraemic syndrome: the C-257T, the A2089G and the G2881T polymorphisms are strongly associated with the disease. Hum Mol Genet (2003) 2.71

Renal progenitors: an evolutionary conserved strategy for kidney regeneration. Nat Rev Nephrol (2013) 2.66

MYO1E mutations and childhood familial focal segmental glomerulosclerosis. N Engl J Med (2011) 2.65

Albuminuria is a target for renoprotective therapy independent from blood pressure in patients with type 2 diabetic nephropathy: post hoc analysis from the Reduction of Endpoints in NIDDM with the Angiotensin II Antagonist Losartan (RENAAL) trial. J Am Soc Nephrol (2007) 2.61

Phosphate may promote CKD progression and attenuate renoprotective effect of ACE inhibition. J Am Soc Nephrol (2011) 2.60

Human bone marrow mesenchymal stem cells accelerate recovery of acute renal injury and prolong survival in mice. Stem Cells (2008) 2.51

Disruption of the Ang II type 1 receptor promotes longevity in mice. J Clin Invest (2009) 2.49

Role of remission clinics in the longitudinal treatment of CKD. J Am Soc Nephrol (2008) 2.48

Immunosuppressive treatment for idiopathic membranous nephropathy: a systematic review. Am J Kidney Dis (2004) 2.43

Sirolimus therapy to halt the progression of ADPKD. J Am Soc Nephrol (2010) 2.42

Risk scores for predicting outcomes in patients with type 2 diabetes and nephropathy: the RENAAL study. Clin J Am Soc Nephrol (2006) 2.37

Safety and efficacy of long-acting somatostatin treatment in autosomal-dominant polycystic kidney disease. Kidney Int (2005) 2.32

Coordinate expression of regulatory genes differentiates embryonic and perinatal forms of biliary atresia. Hepatology (2004) 2.28

Epigenetic mechanisms of regulation of Foxp3 expression. Blood (2009) 2.27

MicroRNA-324-3p promotes renal fibrosis and is a target of ACE inhibition. J Am Soc Nephrol (2012) 2.26

Effect of longacting somatostatin analogue on kidney and cyst growth in autosomal dominant polycystic kidney disease (ALADIN): a randomised, placebo-controlled, multicentre trial. Lancet (2013) 2.23

Ameliorating hypertension and insulin resistance in subjects at increased cardiovascular risk: effects of acetyl-L-carnitine therapy. Hypertension (2009) 2.20

Pretransplant infusion of mesenchymal stem cells prolongs the survival of a semiallogeneic heart transplant through the generation of regulatory T cells. J Immunol (2008) 2.17

Timed urine collections are not needed to measure urine protein excretion in clinical practice. Am J Kidney Dis (2006) 2.17

Massive ex vivo expansion of human natural regulatory T cells (T(regs)) with minimal loss of in vivo functional activity. Sci Transl Med (2011) 2.14

Long-term results with multimodal adjuvant therapy and liver transplantation for the treatment of hepatocellular carcinomas larger than 5 centimeters. Ann Surg (2002) 2.14

The sphingosine 1-phosphate receptor 1 causes tissue retention by inhibiting the entry of peripheral tissue T lymphocytes into afferent lymphatics. Nat Immunol (2007) 2.13

Podocyte number in normotensive type 1 diabetic patients with albuminuria. Diabetes (2002) 2.12

Albuminuria response to very high-dose valsartan in type 2 diabetes mellitus. J Hypertens (2007) 2.12

Insulin-like growth factor-1 sustains stem cell mediated renal repair. J Am Soc Nephrol (2007) 2.02

Progression risk, urinary protein excretion, and treatment effects of angiotensin-converting enzyme inhibitors in nondiabetic kidney disease. J Am Soc Nephrol (2007) 2.00

c-Maf regulates IL-10 expression during Th17 polarization. J Immunol (2009) 1.99

Baseline Analysis of a Young α-1-Antitrypsin Deficiency Liver Disease Cohort Reveals Frequent Portal Hypertension. J Pediatr Gastroenterol Nutr (2015) 1.98

Chronic renal diseases as a public health problem: epidemiology, social, and economic implications. Kidney Int Suppl (2005) 1.96

Severe bile salt export pump deficiency: 82 different ABCB11 mutations in 109 families. Gastroenterology (2008) 1.95

Donor Toll-like receptor 4 contributes to ischemia and reperfusion injury following human kidney transplantation. Proc Natl Acad Sci U S A (2009) 1.95

CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia. Nature (2009) 1.94

Retarding progression of chronic renal disease: the neglected issue of residual proteinuria. Kidney Int (2003) 1.91

The membrane protein ATPase class I type 8B member 1 signals through protein kinase C zeta to activate the farnesoid X receptor. Hepatology (2008) 1.90

Proteasomal processing of albumin by renal dendritic cells generates antigenic peptides. J Am Soc Nephrol (2008) 1.89

STEC-HUS, atypical HUS and TTP are all diseases of complement activation. Nat Rev Nephrol (2012) 1.89

Recurrence of hepatocellular carcinoma after liver transplant: patterns and prognosis. Liver Transpl (2004) 1.88

Autologous mesenchymal stromal cells and kidney transplantation: a pilot study of safety and clinical feasibility. Clin J Am Soc Nephrol (2010) 1.87

von Willebrand factor cleaving protease (ADAMTS13) is deficient in recurrent and familial thrombotic thrombocytopenic purpura and hemolytic uremic syndrome. Blood (2002) 1.85

Imaging of the porous ultrastructure of the glomerular epithelial filtration slit. J Am Soc Nephrol (2010) 1.85

Complex inheritance of familial hypercholanemia with associated mutations in TJP2 and BAAT. Nat Genet (2003) 1.85

Glomerular hyperfiltration and renal disease progression in type 2 diabetes. Diabetes Care (2012) 1.85

Esophageal subepithelial fibrosis in children with eosinophilic esophagitis. J Pediatr Gastroenterol Nutr (2007) 1.85

Implications of the initial mutations in membrane cofactor protein (MCP; CD46) leading to atypical hemolytic uremic syndrome. Mol Immunol (2006) 1.82

Rituximab in idiopathic membranous nephropathy: a one-year prospective study. J Am Soc Nephrol (2003) 1.81

The GFR and GFR decline cannot be accurately estimated in type 2 diabetics. Kidney Int (2013) 1.81

In vivo maturation of functional renal organoids formed from embryonic cell suspensions. J Am Soc Nephrol (2012) 1.81

Extrahepatic anomalies in infants with biliary atresia: results of a large prospective North American multicenter study. Hepatology (2013) 1.80

Mechanisms of disease: Pre-eclampsia. Nat Clin Pract Nephrol (2005) 1.79

Ureteral stents are associated with reduced risk of ureteral complications after kidney transplantation: a large single center experience. Transplantation (2012) 1.79

Intravenous N-acetylcysteine in pediatric patients with nonacetaminophen acute liver failure: a placebo-controlled clinical trial. Hepatology (2013) 1.78

MicroRNA-based classification of hepatocellular carcinoma and oncogenic role of miR-517a. Gastroenterology (2011) 1.77

Measurable urinary albumin predicts cardiovascular risk among normoalbuminuric patients with type 2 diabetes. J Am Soc Nephrol (2012) 1.75

Regulatory T cells and T cell depletion: role of immunosuppressive drugs. J Am Soc Nephrol (2007) 1.75

Impact of blood pressure control and angiotensin-converting enzyme inhibitor therapy on new-onset microalbuminuria in type 2 diabetes: a post hoc analysis of the BENEDICT trial. J Am Soc Nephrol (2006) 1.74

Residual plasmatic activity of ADAMTS13 is correlated with phenotype severity in congenital thrombotic thrombocytopenic purpura. Blood (2012) 1.73

Sirtuin 3-dependent mitochondrial dynamic improvements protect against acute kidney injury. J Clin Invest (2015) 1.71

ACE inhibition is renoprotective among obese patients with proteinuria. J Am Soc Nephrol (2011) 1.70

Validation of a patient-specific hemodynamic computational model for surgical planning of vascular access in hemodialysis patients. Kidney Int (2013) 1.68

Shiga toxin-2 triggers endothelial leukocyte adhesion and transmigration via NF-kappaB dependent up-regulation of IL-8 and MCP-1. Kidney Int (2002) 1.68

Growth failure and outcomes in infants with biliary atresia: a report from the Biliary Atresia Research Consortium. Hepatology (2007) 1.68

Mesenchymal stromal cells and kidney transplantation: pretransplant infusion protects from graft dysfunction while fostering immunoregulation. Transpl Int (2013) 1.67

Eculizumab in a patient with dense-deposit disease. N Engl J Med (2012) 1.67

The RAAS in the pathogenesis and treatment of diabetic nephropathy. Nat Rev Nephrol (2010) 1.65