Mutations in factor H reduce binding affinity to C3b and heparin and surface attachment to endothelial cells in hemolytic uremic syndrome.

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Published in J Clin Invest on April 01, 2003

Authors

Tamara Manuelian1, Jens Hellwage, Seppo Meri, Jessica Caprioli, Marina Noris, Stefan Heinen, Mihaly Jozsi, Hartmut P H Neumann, Giuseppe Remuzzi, Peter F Zipfel

Author Affiliations

1: Hans Knoell Institute for Natural Products Research, Beutenbergstrasse 11a, D-07745 Jena, Germany.

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