Published in Mol Biol Cell on November 12, 2008
Tetraspanin CD151 plays a key role in skin squamous cell carcinoma. Oncogene (2012) 2.16
ARRDC3 suppresses breast cancer progression by negatively regulating integrin beta4. Oncogene (2010) 1.24
EGF-induced MAPK signaling inhibits hemidesmosome formation through phosphorylation of the integrin {beta}4. J Biol Chem (2010) 1.12
Loss of integrin α3 prevents skin tumor formation by promoting epidermal turnover and depletion of slow-cycling cells. Proc Natl Acad Sci U S A (2012) 1.02
Integrin-associated CD151 drives ErbB2-evoked mammary tumor onset and metastasis. Neoplasia (2012) 0.99
Phosphorylation of threonine 1736 in the C-terminal tail of integrin β4 contributes to hemidesmosome disassembly. Mol Biol Cell (2012) 0.93
A complex of α6 integrin and E-cadherin drives liver metastasis of colorectal cancer cells through hepatic angiopoietin-like 6. EMBO Mol Med (2012) 0.91
Role of β4 integrin phosphorylation in human invasive squamous cell carcinoma: regulation of hemidesmosome stability modulates cell migration. Lab Invest (2011) 0.89
Palmitoylation by DHHC3 is critical for the function, expression, and stability of integrin α6β4. Cell Mol Life Sci (2012) 0.88
Transmembrane collagen XVII modulates integrin dependent keratinocyte migration via PI3K/Rac1 signaling. PLoS One (2014) 0.87
Cytoplasmic domain interactions of syndecan-1 and syndecan-4 with α6β4 integrin mediate human epidermal growth factor receptor (HER1 and HER2)-dependent motility and survival. J Biol Chem (2014) 0.86
Molecular architecture and function of the hemidesmosome. Cell Tissue Res (2014) 0.83
The calcium/calcineurin pathway promotes hemidesmosome stability through inhibition of β4 integrin phosphorylation. J Biol Chem (2012) 0.82
Quantification of pancreatic cancer proteome and phosphorylome: indicates molecular events likely contributing to cancer and activity of drug targets. PLoS One (2014) 0.82
Syndecan-1 and Its Expanding List of Contacts. Adv Wound Care (New Rochelle) (2015) 0.80
The role of integrins in the development and homeostasis of the epidermis and skin appendages. Acta Naturae (2013) 0.78
Molecular architecture and function of the hemidesmosome. Cell Tissue Res (2015) 0.77
Curcumin Prevents Palmitoylation of Integrin β4 in Breast Cancer Cells. PLoS One (2015) 0.76
Pancreatic cancer stem cell markers and exosomes - the incentive push. World J Gastroenterol (2016) 0.76
PKD2 and RSK1 Regulate Integrin β4 Phosphorylation at Threonine 1736. PLoS One (2015) 0.76
Loss of MMP-8 in ductal carcinoma in situ (DCIS)-associated myoepithelial cells contributes to tumour promotion through altered adhesive and proteolytic function. Breast Cancer Res (2017) 0.75
Integrins: versatility, modulation, and signaling in cell adhesion. Cell (1992) 34.06
Cell migration: integrating signals from front to back. Science (2003) 29.13
Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates. Methods Enzymol (1991) 15.04
Spatiotemporal dynamics of RhoA activity in migrating cells. Nature (2006) 6.84
Distinct functions for integrins alpha 3 beta 1 in focal adhesions and alpha 6 beta 4/bullous pemphigoid antigen in a new stable anchoring contact (SAC) of keratinocytes: relation to hemidesmosomes. J Cell Biol (1990) 3.00
Regulation of cell migration by the calcium-dependent protease calpain. J Biol Chem (1997) 2.52
EGF-R signaling through Fyn kinase disrupts the function of integrin alpha6beta4 at hemidesmosomes: role in epithelial cell migration and carcinoma invasion. J Cell Biol (2001) 2.46
The integrin alpha6beta4 functions in carcinoma cell migration on laminin-1 by mediating the formation and stabilization of actin-containing motility structures. J Cell Biol (1997) 2.03
Protein kinase C-dependent mobilization of the alpha6beta4 integrin from hemidesmosomes and its association with actin-rich cell protrusions drive the chemotactic migration of carcinoma cells. J Cell Biol (1999) 1.98
The MSP receptor regulates alpha6beta4 and alpha3beta1 integrins via 14-3-3 proteins in keratinocyte migration. Dev Cell (2003) 1.91
Current insights into the formation and breakdown of hemidesmosomes. Trends Cell Biol (2006) 1.79
The intracellular functions of alpha6beta4 integrin are regulated by EGF. J Cell Biol (1996) 1.73
Desmosomes and hemidesmosomes: structure and function of molecular components. FASEB J (1996) 1.70
Tyrosine phosphorylation of the beta 4 integrin cytoplasmic domain mediates Shc signaling to extracellular signal-regulated kinase and antagonizes formation of hemidesmosomes. J Biol Chem (2001) 1.66
Laminin receptors: achieving specificity through cooperation. Trends Cell Biol (1995) 1.62
Identification of a new hemidesmosomal protein, HD1: a major, high molecular mass component of isolated hemidesmosomes. J Cell Biol (1992) 1.57
Analysis of the interactions between BP180, BP230, plectin and the integrin alpha6beta4 important for hemidesmosome assembly. J Cell Sci (2003) 1.52
Biology and function of hemidesmosomes. Matrix Biol (1999) 1.51
Gö 6976, a selective inhibitor of protein kinase C, is a potent antagonist of human immunodeficiency virus 1 induction from latent/low-level-producing reservoir cells in vitro. Proc Natl Acad Sci U S A (1993) 1.44
Role of binding of plectin to the integrin beta4 subunit in the assembly of hemidesmosomes. Mol Biol Cell (2003) 1.41
FAK, PDZ-RhoGEF and ROCKII cooperate to regulate adhesion movement and trailing-edge retraction in fibroblasts. J Cell Sci (2008) 1.36
Protein kinase C-alpha phosphorylation of specific serines in the connecting segment of the beta 4 integrin regulates the dynamics of type II hemidesmosomes. Mol Cell Biol (2004) 1.31
Dynamics of the alpha6beta4 integrin in keratinocytes. Mol Biol Cell (2002) 1.29
Serine phosphorylation of the integrin beta4 subunit is necessary for epidermal growth factor receptor induced hemidesmosome disruption. Mol Biol Cell (2007) 1.22
Redistribution of the hemidesmosome components alpha 6 beta 4 integrin and bullous pemphigoid antigens during epithelial wound healing. Exp Cell Res (1993) 1.22
Monoclonal antibody to human carcinoma-associated protein complex: quantitation in normal and tumor tissue. Cancer Res (1988) 1.20
Extracellular matrix components and integrins in relationship to human intestinal epithelial cell differentiation. Prog Histochem Cytochem (1997) 1.17
Calpain proteases in cell adhesion and motility. Int Rev Cytol (2005) 1.14
Demonstration of type II hemidesmosomes in a mammary gland epithelial cell line, BMGE-H. J Biochem (1994) 1.14
Metastatic growth of squamous cell carcinomas is correlated with upregulation and redistribution of hemidesmosomal components. Cell Tissue Res (2001) 1.10
The role of alpha3beta1 integrin in determining the supramolecular organization of laminin-5 in the extracellular matrix of keratinocytes. Exp Cell Res (2003) 1.09
Specificity of binding of the plectin actin-binding domain to beta4 integrin. Mol Biol Cell (2003) 1.09
Hemidesmosome protein dynamics in live epithelial cells. Cell Motil Cytoskeleton (2003) 1.08
Increase in suprabasilar integrin adhesion molecule expression in human epidermal neoplasms accompanies increased proliferation occurring with immortalization and tumor progression. Cancer Res (1995) 1.05
Hemidesmosomes in the epithelial cell line 804G: their fate during wound closure, mitosis and drug induced reorganization of the cytoskeleton. J Cell Sci (1992) 0.98
Overexpression of the A9 antigen/alpha 6 beta 4 integrin in head and neck cancer. Otolaryngol Clin North Am (1992) 0.88
Calcium signalling: the ups and downs of protein kinase C. Curr Biol (2003) 0.86
Akt blocks breast cancer cell motility and invasion through the transcription factor NFAT. Mol Cell (2005) 3.78
Ribosomal S6 kinase (RSK) regulates phosphorylation of filamin A on an important regulatory site. Mol Cell Biol (2004) 1.81
RhoB controls Akt trafficking and stage-specific survival of endothelial cells during vascular development. Genes Dev (2003) 1.48
Protein phosphatase 2A reactivates FOXO3a through a dynamic interplay with 14-3-3 and AKT. Mol Biol Cell (2010) 1.29
Integrin-associated CD151 drives ErbB2-evoked mammary tumor onset and metastasis. Neoplasia (2012) 0.99
Use of RNA interference to inhibit integrin (alpha6beta4)-mediated invasion and migration of breast carcinoma cells. Clin Exp Metastasis (2003) 0.99
Priming of the vascular endothelial growth factor signaling pathway by thrombospondin-1, CD36, and spleen tyrosine kinase. Blood (2011) 0.95
Role of β4 integrin phosphorylation in human invasive squamous cell carcinoma: regulation of hemidesmosome stability modulates cell migration. Lab Invest (2011) 0.89
Palmitoylation by DHHC3 is critical for the function, expression, and stability of integrin α6β4. Cell Mol Life Sci (2012) 0.88
The calcium/calcineurin pathway promotes hemidesmosome stability through inhibition of β4 integrin phosphorylation. J Biol Chem (2012) 0.82