Published in Anal Chem on December 15, 2008
Nanoparticle PEGylation for imaging and therapy. Nanomedicine (Lond) (2011) 3.33
Biocompatibility, biodistribution, and drug-delivery efficiency of mesoporous silica nanoparticles for cancer therapy in animals. Small (2010) 2.10
In vivo tumor targeting and image-guided drug delivery with antibody-conjugated, radiolabeled mesoporous silica nanoparticles. ACS Nano (2013) 1.34
Surface charge-mediated rapid hepatobiliary excretion of mesoporous silica nanoparticles. Biomaterials (2010) 1.29
Clearance Pathways and Tumor Targeting of Imaging Nanoparticles. ACS Nano (2015) 1.25
Mesoporous silica nanoparticles facilitate delivery of siRNA to shutdown signaling pathways in mammalian cells. Small (2010) 1.23
PEGylation and zwitterionization: pros and cons in the renal clearance and tumor targeting of near-IR-emitting gold nanoparticles. Angew Chem Int Ed Engl (2013) 1.23
Synthesis and biological response of size-specific, monodisperse drug-silica nanoconjugates. ACS Nano (2012) 1.23
Nucleic acid conjugated nanomaterials for enhanced molecular recognition. ACS Nano (2009) 1.13
Silica-based nanoprobes for biomedical imaging and theranostic applications. Chem Soc Rev (2012) 1.13
Near-infrared phosphorescent polymeric nanomicelles: efficient optical probes for tumor imaging and detection. ACS Appl Mater Interfaces (2009) 1.10
Targeted delivery of nanoparticles to ischemic muscle for imaging and therapeutic angiogenesis. Nano Lett (2010) 1.08
Fabrication of corona-free nanoparticles with tunable hydrophobicity. ACS Nano (2014) 1.07
In vivo tumor suppression efficacy of mesoporous silica nanoparticles-based drug-delivery system: enhanced efficacy by folate modification. Nanomedicine (2011) 1.05
Phosphorescent nanoscale coordination polymers as contrast agents for optical imaging. Angew Chem Int Ed Engl (2011) 1.04
Nonporous Silica Nanoparticles for Nanomedicine Application. Nano Today (2013) 1.04
Biologically optimized nanosized molecules and particles: more than just size. Bioconjug Chem (2011) 1.00
Microgel translocation through pores under confinement. Angew Chem Int Ed Engl (2010) 0.99
Engineered nanomaterial uptake and tissue distribution: from cell to organism. Int J Nanomedicine (2013) 0.95
Silica-based nanoparticle uptake and cellular response by primary microglia. Environ Health Perspect (2010) 0.95
Color Doppler ultrasound and gamma imaging of intratumorally injected 500 nm iron-silica nanoshells. ACS Nano (2013) 0.94
In vitro evaluation of theranostic polymeric micelles for imaging and drug delivery in cancer. Theranostics (2012) 0.93
Inorganic-organic hybrid nanomaterials for therapeutic and diagnostic imaging applications. Int J Mol Sci (2011) 0.93
Size-dependent tumor penetration and in vivo efficacy of monodisperse drug-silica nanoconjugates. Mol Pharm (2013) 0.93
Nitric oxide-releasing silica nanoparticle inhibition of ovarian cancer cell growth. Mol Pharm (2010) 0.89
Synthesis and surface functionalization of silica nanoparticles for nanomedicine. Surf Sci Rep (2014) 0.88
Xenobiotic particle exposure and microvascular endpoints: a call to arms. Microcirculation (2012) 0.88
Determining the pharmacokinetics and long-term biodistribution of SiO2 nanoparticles in vivo using accelerator mass spectrometry. Nano Lett (2012) 0.87
Facile synthesis, silanization, and biodistribution of biocompatible quantum dots. Small (2010) 0.87
Nanostructured porous Si-based nanoparticles for targeted drug delivery. Biomatter (2013) 0.86
Promising plasmid DNA vector based on APTES-modified silica nanoparticles. Int J Nanomedicine (2012) 0.86
Tissue distribution and excretion kinetics of orally administered silica nanoparticles in rats. Int J Nanomedicine (2014) 0.86
Silica nanoparticles as a delivery system for nucleic acid-based reagents. J Mater Chem (2009) 0.85
Nanoparticle Uptake: The Phagocyte Problem. Nano Today (2015) 0.84
Toxic and teratogenic silica nanowires in developing vertebrate embryos. Nanomedicine (2009) 0.84
Development of mesoporous silica nanomaterials as a vehicle for anticancer drug delivery. Ther Deliv (2012) 0.84
Inorganic nanomaterials for tumor angiogenesis imaging. Eur J Nucl Med Mol Imaging (2010) 0.83
Iron(III)-doped, silica nanoshells: a biodegradable form of silica. J Am Chem Soc (2012) 0.83
Amine modification of nonporous silica nanoparticles reduces inflammatory response following intratracheal instillation in murine lungs. Toxicol Lett (2015) 0.82
Recent development of silica nanoparticles as delivery vectors for cancer imaging and therapy. Nanomedicine (2013) 0.81
Vectors for inhaled gene therapy in lung cancer. Application for nano oncology and safety of bio nanotechnology. Int J Mol Sci (2012) 0.80
Rapid Hepatobiliary Excretion of Micelle-Encapsulated/Radiolabeled Upconverting Nanoparticles as an Integrated Form. Sci Rep (2015) 0.80
Silica Nanoparticle-Generated ROS as a Predictor of Cellular Toxicity: Mechanistic Insights and Safety by Design. Environ Sci Nano (2015) 0.80
Diverse Applications of Nanomedicine. ACS Nano (2017) 0.80
Local targeted therapy of liver metastasis from colon cancer by galactosylated liposome encapsulated with doxorubicin. PLoS One (2013) 0.78
Delivery of therapeutic radioisotopes using nanoparticle platforms: potential benefit in systemic radiation therapy. Nanotechnol Sci Appl (2010) 0.78
Ternary hybrid nanocomposites for gene delivery and magnetic resonance imaging of hepatocellular carcinoma cells. Quant Imaging Med Surg (2013) 0.77
Delivery of chemotropic proteins and improvement of dopaminergic neuron outgrowth through a thixotropic hybrid nano-gel. J Mater Sci Mater Med (2011) 0.77
Improved Auditory Nerve Survival with Nanoengineered Supraparticles for Neurotrophin Delivery into the Deafened Cochlea. PLoS One (2016) 0.75
A comparison between sphere and rod nanoparticles regarding their in vivo biological behavior and pharmacokinetics. Sci Rep (2017) 0.75
Mesoporous silica nanoparticles synthesized from liquid crystal display manufacturing extracts as a potential candidate for a drug delivery carrier: evaluation of their safety and biocompatibility. Int J Nanomedicine (2013) 0.75
Secondary nuclear targeting of mesoporous silica nano-particles for cancer-specific drug delivery based on charge inversion. Oncotarget (2016) 0.75
Evaluation of biocompatible alginate- and deferoxamine-coated ternary composites for magnetic resonance imaging and gene delivery into glioblastoma cells. Quant Imaging Med Surg (2015) 0.75
Hemopexin as biomarkers for analyzing the biological responses associated with exposure to silica nanoparticles. Nanoscale Res Lett (2012) 0.75
Preparation and Characterization of Double Shell Fe3O4 Cluster@Nonporous SiO2@Mesoporous SiO2 Nanocomposite Spheres and Investigation of their In Vitro Biocompatibility. Iran J Biotechnol (2015) 0.75
Aptamers evolved from live cells as effective molecular probes for cancer study. Proc Natl Acad Sci U S A (2006) 5.35
The renewal and differentiation of Isl1+ cardiovascular progenitors are controlled by a Wnt/beta-catenin pathway. Cell Stem Cell (2007) 3.54
A stem cell-based approach to cartilage repair. Science (2012) 3.22
Single-nucleotide mutation rate increases close to insertions/deletions in eukaryotes. Nature (2008) 3.13
miR-214 targets ATF4 to inhibit bone formation. Nat Med (2012) 3.01
Interfering with resistance to smoothened antagonists by inhibition of the PI3K pathway in medulloblastoma. Sci Transl Med (2010) 2.86
Development of DNA aptamers using Cell-SELEX. Nat Protoc (2010) 2.62
Selection of aptamers for molecular recognition and characterization of cancer cells. Anal Chem (2007) 2.57
Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974. Proc Natl Acad Sci U S A (2013) 2.49
Aptamers generated from cell-SELEX for molecular medicine: a chemical biology approach. Acc Chem Res (2010) 2.48
Cell-specific aptamer probes for membrane protein elucidation in cancer cells. J Proteome Res (2008) 2.44
Surface modification of silica nanoparticles to reduce aggregation and nonspecific binding. Langmuir (2006) 2.17
Topical treatment of Basal cell carcinomas in nevoid Basal cell carcinoma syndrome with a smoothened inhibitor. J Invest Dermatol (2011) 1.98
Aptamer directly evolved from live cells recognizes membrane bound immunoglobin heavy mu chain in Burkitt's lymphoma cells. Mol Cell Proteomics (2007) 1.98
Identification of serum-derived sphingosine-1-phosphate as a small molecule regulator of YAP. Chem Biol (2012) 1.91
Identification of liver cancer-specific aptamers using whole live cells. Anal Chem (2008) 1.90
A rapid bioassay for single bacterial cell quantitation using bioconjugated nanoparticles. Proc Natl Acad Sci U S A (2004) 1.87
Molecular engineering of DNA: molecular beacons. Angew Chem Int Ed Engl (2009) 1.84
Gold nanoparticle-based colorimetric assay for the direct detection of cancerous cells. Anal Chem (2008) 1.84
Bionanotechnology based on silica nanoparticles. Med Res Rev (2004) 1.81
Cell-specific internalization study of an aptamer from whole cell selection. Chemistry (2008) 1.81
Light-switching excimer probes for rapid protein monitoring in complex biological fluids. Proc Natl Acad Sci U S A (2005) 1.80
A combinatorial scaffold approach toward kinase-directed heterocycle libraries. J Am Chem Soc (2002) 1.79
Glycogen synthase kinase 3 inhibitors induce the canonical WNT/β-catenin pathway to suppress growth and self-renewal in embryonal rhabdomyosarcoma. Proc Natl Acad Sci U S A (2014) 1.79
Enrichment of cancer cells using aptamers immobilized on a microfluidic channel. Anal Chem (2009) 1.78
A small molecule primes embryonic stem cells for differentiation. Cell Stem Cell (2009) 1.78
Aptamer-modified gold nanoparticles for colorimetric determination of platelet-derived growth factors and their receptors. Anal Chem (2005) 1.76
Optimization and modifications of aptamers selected from live cancer cell lines. Chembiochem (2007) 1.76
Ultrasensitive DNA detection using highly fluorescent bioconjugated nanoparticles. J Am Chem Soc (2003) 1.74
Molecular assembly of an aptamer-drug conjugate for targeted drug delivery to tumor cells. Chembiochem (2009) 1.73
Molecular recognition of small-cell lung cancer cells using aptamers. ChemMedChem (2008) 1.71
Aptamers evolved from cultured cancer cells reveal molecular differences of cancer cells in patient samples. Clin Chem (2007) 1.69
TRPM8 mechanism of cold allodynia after chronic nerve injury. J Neurosci (2007) 1.69
The mitochondrial pathway of anesthetic isoflurane-induced apoptosis. J Biol Chem (2009) 1.64
Aptamer-based microfluidic device for enrichment, sorting, and detection of multiple cancer cells. Anal Chem (2009) 1.61
Ca2+/calmodulin-dependent protein kinase IIdelta and protein kinase D overexpression reinforce the histone deacetylase 5 redistribution in heart failure. Circ Res (2008) 1.58
Aptamer-conjugated nanoparticles for selective collection and detection of cancer cells. Anal Chem (2006) 1.58
Dedifferentiation of lineage-committed cells by a small molecule. J Am Chem Soc (2004) 1.56
DNA aptamer-micelle as an efficient detection/delivery vehicle toward cancer cells. Proc Natl Acad Sci U S A (2009) 1.56
Aptamer-conjugated nanoparticles for the collection and detection of multiple cancer cells. Anal Chem (2007) 1.55
Cancer cell targeting using multiple aptamers conjugated on nanorods. Anal Chem (2008) 1.55
Optimization of dye-doped silica nanoparticles prepared using a reverse microemulsion method. Langmuir (2004) 1.52
Locked nucleic acid molecular beacons. J Am Chem Soc (2005) 1.51
Molecular aptamer beacons for real-time protein recognition. Biochem Biophys Res Commun (2002) 1.49
Activatable aptamer probe for contrast-enhanced in vivo cancer imaging based on cell membrane protein-triggered conformation alteration. Proc Natl Acad Sci U S A (2011) 1.48
Molecular assembly for high-performance bivalent nucleic acid inhibitor. Proc Natl Acad Sci U S A (2008) 1.44
A small-molecule agonist of the Wnt signaling pathway. Angew Chem Int Ed Engl (2005) 1.44
DNA-functionalized nanotube membranes with single-base mismatch selectivity. Science (2004) 1.44
Aptamer-enabled efficient isolation of cancer cells from whole blood using a microfluidic device. Anal Chem (2012) 1.44
Isoflurane-induced caspase-3 activation is dependent on cytosolic calcium and can be attenuated by memantine. J Neurosci (2008) 1.44
Carbon nanotube-quenched fluorescent oligonucleotides: probes that fluoresce upon hybridization. J Am Chem Soc (2008) 1.43
Multicolor FRET silica nanoparticles by single wavelength excitation. Nano Lett (2006) 1.40
Aptamer switch probe based on intramolecular displacement. J Am Chem Soc (2008) 1.40
Bioconjugated nanoparticles for DNA protection from cleavage. J Am Chem Soc (2003) 1.39
Anesthetic sevoflurane causes neurotoxicity differently in neonatal naïve and Alzheimer disease transgenic mice. Anesthesiology (2010) 1.38
Selective photothermal therapy for mixed cancer cells using aptamer-conjugated nanorods. Langmuir (2008) 1.37
DNA aptamers as molecular probes for colorectal cancer study. PLoS One (2010) 1.36
Uptake of silica-coated nanoparticles by HeLa cells. J Nanosci Nanotechnol (2005) 1.36
Assembly of aptamer switch probes and photosensitizer on gold nanorods for targeted photothermal and photodynamic cancer therapy. ACS Nano (2012) 1.32
Generating aptamers for recognition of virus-infected cells. Clin Chem (2009) 1.31
Single-step assembly of DOX/ICG loaded lipid--polymer nanoparticles for highly effective chemo-photothermal combination therapy. ACS Nano (2013) 1.31
A snake-based method for segmentation of intravascular ultrasound images and its in vivo validation. Ultrasonics (2010) 1.30
Self-assembled, aptamer-tethered DNA nanotrains for targeted transport of molecular drugs in cancer theranostics. Proc Natl Acad Sci U S A (2013) 1.29
Compatibility art of traditional Chinese medicine: from the perspective of herb pairs. J Ethnopharmacol (2012) 1.29
Noncanonical self-assembly of multifunctional DNA nanoflowers for biomedical applications. J Am Chem Soc (2013) 1.26
Study of the molecular recognition of aptamers selected through ovarian cancer cell-SELEX. PLoS One (2010) 1.26
In vivo near-infrared fluorescence imaging of cancer with nanoparticle-based probes. Wiley Interdiscip Rev Nanomed Nanobiotechnol (2010) 1.26
Inhibition of histone deacetylase activity induces developmental plasticity in oligodendrocyte precursor cells. Proc Natl Acad Sci U S A (2007) 1.26
Synthetic DNA aptamers to detect protein molecular variants in a high-throughput fluorescence quenching assay. Chembiochem (2003) 1.26
Regulation of singlet oxygen generation using single-walled carbon nanotubes. J Am Chem Soc (2008) 1.23
Recognition of subtype non-small cell lung cancer by DNA aptamers selected from living cells. Analyst (2009) 1.22
Identification of RING finger protein 4 (RNF4) as a modulator of DNA demethylation through a functional genomics screen. Proc Natl Acad Sci U S A (2010) 1.22
Fighting fire with fire: poisonous Chinese herbal medicine for cancer therapy. J Ethnopharmacol (2012) 1.22
Collection of trace amounts of DNA/mRNA molecules using genomagnetic nanocapturers. Anal Chem (2003) 1.21
Aptamer-nanoparticle strip biosensor for sensitive detection of cancer cells. Anal Chem (2009) 1.20
FloDots: luminescent nanoparticles. Anal Bioanal Chem (2006) 1.20
Identification of small-molecule inducers of pancreatic beta-cell expansion. Proc Natl Acad Sci U S A (2009) 1.20
Pyrene excimer signaling molecular beacons for probing nucleic acids. J Am Chem Soc (2007) 1.20
TAT conjugated, FITC doped silica nanoparticles for bioimaging applications. Chem Commun (Camb) (2004) 1.19
DNA-based micelles: synthesis, micellar properties and size-dependent cell permeability. Chemistry (2010) 1.18
Identification of metastasis associated proteins in human lung squamous carcinoma using two-dimensional difference gel electrophoresis and laser capture microdissection. Lung Cancer (2008) 1.18
Nitrous oxide plus isoflurane induces apoptosis and increases beta-amyloid protein levels. Anesthesiology (2009) 1.17
Ultrasensitive detection of biomolecules with fluorescent dye-doped nanoparticles. Anal Biochem (2004) 1.17
Nucleic acid aptamers for biosensors and bio-analytical applications. Analyst (2009) 1.16
An aptamer cross-linked hydrogel as a colorimetric platform for visual detection. Angew Chem Int Ed Engl (2010) 1.16
Simultaneous monitoring of the expression of multiple genes inside of single breast carcinoma cells. Anal Chem (2005) 1.16
Dual-luminophore-doped silica nanoparticles for multiplexed signaling. Nano Lett (2005) 1.15
Nanotechnology in therapeutics: a focus on nanoparticles as a drug delivery system. Nanomedicine (Lond) (2012) 1.15
Effects of sporulation conditions on the germination and germination protein levels of Bacillus subtilis spores. Appl Environ Microbiol (2012) 1.14
Carbon nanotubes protect DNA strands during cellular delivery. ACS Nano (2008) 1.14
Molecular assembly of superquenchers in signaling molecular interactions. J Am Chem Soc (2005) 1.14
Methylene blue-encapsulated phosphonate-terminated silica nanoparticles for simultaneous in vivo imaging and photodynamic therapy. Biomaterials (2009) 1.14