Published in Proc Natl Acad Sci U S A on February 22, 2011
Assembly of aptamer switch probes and photosensitizer on gold nanorods for targeted photothermal and photodynamic cancer therapy. ACS Nano (2012) 1.32
Nucleic acid aptamers: clinical applications and promising new horizons. Curr Med Chem (2011) 1.30
Aptamers from cell-based selection for bioanalytical applications. Chem Rev (2013) 1.30
New Technologies Provide Quantum Changes in the Scale, Speed, and Success of SELEX Methods and Aptamer Characterization. Mol Ther Nucleic Acids (2014) 1.21
Whole cell-SELEX aptamers for highly specific fluorescence molecular imaging of carcinomas in vivo. PLoS One (2013) 1.08
Novel aptamer-nanoparticle bioconjugates enhances delivery of anticancer drug to MUC1-positive cancer cells in vitro. PLoS One (2011) 1.05
Cell-specific aptamers as emerging therapeutics. J Nucleic Acids (2011) 1.04
Nucleic acid aptamers: an emerging frontier in cancer therapy. Chem Commun (Camb) (2012) 0.99
Molecular imaging with nucleic acid aptamers. Curr Med Chem (2011) 0.96
Advance of molecular imaging technology and targeted imaging agent in imaging and therapy. Biomed Res Int (2014) 0.94
Semiquantification of ATP in live cells using nonspecific desorption of DNA from graphene oxide as the internal reference. Anal Chem (2012) 0.94
A cancer cell-activatable aptamer-reporter system for one-step assay of circulating tumor cells. Mol Ther Nucleic Acids (2014) 0.92
DNA Aptamer Selected against Pancreatic Ductal Adenocarcinoma for in vivo Imaging and Clinical Tissue Recognition. Theranostics (2015) 0.89
Novel molecular and nanosensors for in vivo sensing. Theranostics (2013) 0.89
Rationally designed molecular beacons for bioanalytical and biomedical applications. Chem Soc Rev (2015) 0.89
Photosensitizer-gold nanorod composite for targeted multimodal therapy. Small (2013) 0.89
Current progress of aptamer-based molecular imaging. J Nucl Med (2014) 0.88
Generation of lung adenocarcinoma DNA aptamers for cancer studies. PLoS One (2012) 0.85
Specific and sensitive tumor imaging using biostable oligonucleotide aptamer probes. Theranostics (2014) 0.84
Aptamers: active targeting ligands for cancer diagnosis and therapy. Theranostics (2015) 0.84
Profluorogenic reductase substrate for rapid, selective, and sensitive visualization and detection of human cancer cells that overexpress NQO1. J Am Chem Soc (2012) 0.83
Ortho-Stabilized (18) F-Azido Click Agents and their Application in PET Imaging with Single-Stranded DNA Aptamers. Angew Chem Int Ed Engl (2015) 0.82
RNA plasticity and selectivity applicable to therapeutics and novel biosensor development. Genes Cells (2012) 0.82
Superior Performance of Aptamer in Tumor Penetration over Antibody: Implication of Aptamer-Based Theranostics in Solid Tumors. Theranostics (2015) 0.81
DNA Aptamer Technology for Personalized Medicine. Curr Opin Chem Eng (2014) 0.81
18F-Labeled Single-Stranded DNA Aptamer for PET Imaging of Protein Tyrosine Kinase-7 Expression. J Nucl Med (2015) 0.81
Aptamer-based molecular imaging. Protein Cell (2012) 0.80
Nucleic Acid Aptamers as Potential Therapeutic and Diagnostic Agents for Lymphoma. J Cancer Ther (2013) 0.80
Applications of aptamers in targeted imaging: state of the art. Curr Top Med Chem (2015) 0.79
Direct validation of aptamers as powerful tools to image solid tumor. Nucleic Acid Ther (2014) 0.79
Use of a conformational switching aptamer for rapid and specific ex vivo identification of central nervous system lymphoma in a xenograft model. PLoS One (2015) 0.77
Targeting and Imaging of Cancer Cells via Monosaccharide-Imprinted Fluorescent Nanoparticles. Sci Rep (2016) 0.77
Molecular beacon aptamers for direct and universal quantitation of recombinant proteins from cell lysates. Anal Chem (2012) 0.76
Nucleic Acid Aptamers: An Emerging Tool for Biotechnology and Biomedical Sensing. Sensors (Basel) (2015) 0.76
Aptamer technology for tracking cells' status & function. Mol Cell Ther (2014) 0.76
Characterization of the specific interaction between the DNA aptamer sgc8c and protein tyrosine kinase-7 receptors at the surface of T-cells by biosensing AFM. Anal Bioanal Chem (2017) 0.75
Aptamers: versatile molecular recognition probes for cancer detection. Analyst (2016) 0.75
Aptamers Selected by Cell-SELEX for Molecular Imaging. J Mol Evol (2015) 0.75
Strategies for using nanoprobes to perceive and treat cancer activity: a review. J Biol Eng (2017) 0.75
DNA Aptamers for the Characterization of Histological Structure of Lung Adenocarcinoma. Mol Ther Nucleic Acids (2016) 0.75
Synthesis and antibacterial activities of antibacterial peptides with a spiropyran fluorescence probe. Sci Rep (2014) 0.75
Peptide-fluorescent bacteria complex as luminescent reagents for cancer diagnosis. PLoS One (2013) 0.75
Molecular Elucidation of Disease Biomarkers at the Interface of Chemistry and Biology. J Am Chem Soc (2017) 0.75
Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science (1990) 35.96
In vitro selection of RNA molecules that bind specific ligands. Nature (1990) 30.19
Receptor-targeted optical imaging of tumors with near-infrared fluorescent ligands. Nat Biotechnol (2001) 11.41
In vivo near-infrared fluorescence imaging. Curr Opin Chem Biol (2003) 10.76
In vivo imaging of tumors with protease-activated near-infrared fluorescent probes. Nat Biotechnol (1999) 8.46
Aptamers evolved from live cells as effective molecular probes for cancer study. Proc Natl Acad Sci U S A (2006) 5.35
Tumor imaging by means of proteolytic activation of cell-penetrating peptides. Proc Natl Acad Sci U S A (2004) 4.95
A tenascin-C aptamer identified by tumor cell SELEX: systematic evolution of ligands by exponential enrichment. Proc Natl Acad Sci U S A (2003) 3.28
Selective molecular imaging of viable cancer cells with pH-activatable fluorescence probes. Nat Med (2008) 3.15
Activatable cell penetrating peptides linked to nanoparticles as dual probes for in vivo fluorescence and MR imaging of proteases. Proc Natl Acad Sci U S A (2010) 3.03
Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes. Nat Chem Biol (2007) 2.80
Tumor targeting by an aptamer. J Nucl Med (2006) 2.68
Aptamers generated from cell-SELEX for molecular medicine: a chemical biology approach. Acc Chem Res (2010) 2.48
Cell-specific aptamer probes for membrane protein elucidation in cancer cells. J Proteome Res (2008) 2.44
Optical imaging for cervical cancer detection: solutions for a continuing global problem. Nat Rev Cancer (2008) 1.84
Molecular engineering of DNA: molecular beacons. Angew Chem Int Ed Engl (2009) 1.84
Gold nanoparticle-based colorimetric assay for the direct detection of cancerous cells. Anal Chem (2008) 1.84
A target cell-specific activatable fluorescence probe for in vivo molecular imaging of cancer based on a self-quenched avidin-rhodamine conjugate. Cancer Res (2007) 1.64
Superparamagnetic iron oxide nanoparticle-aptamer bioconjugates for combined prostate cancer imaging and therapy. ChemMedChem (2008) 1.57
H-type dimer formation of fluorophores: a mechanism for activatable, in vivo optical molecular imaging. ACS Chem Biol (2009) 1.56
DNA aptamer-micelle as an efficient detection/delivery vehicle toward cancer cells. Proc Natl Acad Sci U S A (2009) 1.56
Aptamer-conjugated nanoparticles for the collection and detection of multiple cancer cells. Anal Chem (2007) 1.55
Application of locked nucleic acids to improve aptamer in vivo stability and targeting function. Nucleic Acids Res (2004) 1.54
A nucleolin-targeted multimodal nanoparticle imaging probe for tracking cancer cells using an aptamer. J Nucl Med (2009) 1.51
Fluorophore-quencher based activatable targeted optical probes for detecting in vivo cancer metastases. Mol Pharm (2009) 1.42
Aptamer switch probe based on intramolecular displacement. J Am Chem Soc (2008) 1.40
Activatable fluorescent molecular imaging of peritoneal metastases following pretargeting with a biotinylated monoclonal antibody. Cancer Res (2007) 1.37
In vivo imaging of oligonucleotides with positron emission tomography. Nat Med (1998) 1.15
In vivo fluorescence imaging of tumors using molecular aptamers generated by cell-SELEX. Chem Asian J (2010) 1.13
Genetic, clinical, and radiographic delineation of Hallervorden-Spatz syndrome. N Engl J Med (2003) 6.47
Aptamers evolved from live cells as effective molecular probes for cancer study. Proc Natl Acad Sci U S A (2006) 5.35
Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer. Cell (2012) 3.77
The renewal and differentiation of Isl1+ cardiovascular progenitors are controlled by a Wnt/beta-catenin pathway. Cell Stem Cell (2007) 3.54
A stem cell-based approach to cartilage repair. Science (2012) 3.22
Quantum-sized carbon dots for bright and colorful photoluminescence. J Am Chem Soc (2006) 3.08
Interfering with resistance to smoothened antagonists by inhibition of the PI3K pathway in medulloblastoma. Sci Transl Med (2010) 2.86
Development of DNA aptamers using Cell-SELEX. Nat Protoc (2010) 2.62
Selection of aptamers for molecular recognition and characterization of cancer cells. Anal Chem (2007) 2.57
Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974. Proc Natl Acad Sci U S A (2013) 2.49
Aptamers generated from cell-SELEX for molecular medicine: a chemical biology approach. Acc Chem Res (2010) 2.48
Cell-specific aptamer probes for membrane protein elucidation in cancer cells. J Proteome Res (2008) 2.44
A novel member of a zinc transporter family is defective in acrodermatitis enteropathica. Am J Hum Genet (2002) 2.41
Dementia subtypes in China: prevalence in Beijing, Xian, Shanghai, and Chengdu. Arch Neurol (2005) 2.39
Surface modification of silica nanoparticles to reduce aggregation and nonspecific binding. Langmuir (2006) 2.17
Topical treatment of Basal cell carcinomas in nevoid Basal cell carcinoma syndrome with a smoothened inhibitor. J Invest Dermatol (2011) 1.98
Aptamer directly evolved from live cells recognizes membrane bound immunoglobin heavy mu chain in Burkitt's lymphoma cells. Mol Cell Proteomics (2007) 1.98
Identification of serum-derived sphingosine-1-phosphate as a small molecule regulator of YAP. Chem Biol (2012) 1.91
Identification of liver cancer-specific aptamers using whole live cells. Anal Chem (2008) 1.90
A rapid bioassay for single bacterial cell quantitation using bioconjugated nanoparticles. Proc Natl Acad Sci U S A (2004) 1.87
Inferring causal relationships among different histone modifications and gene expression. Genome Res (2008) 1.84
Molecular engineering of DNA: molecular beacons. Angew Chem Int Ed Engl (2009) 1.84
Gold nanoparticle-based colorimetric assay for the direct detection of cancerous cells. Anal Chem (2008) 1.84
Chlamydia trachomatis plasmid-encoded Pgp4 is a transcriptional regulator of virulence-associated genes. Infect Immun (2013) 1.82
Bionanotechnology based on silica nanoparticles. Med Res Rev (2004) 1.81
Cell-specific internalization study of an aptamer from whole cell selection. Chemistry (2008) 1.81
Light-switching excimer probes for rapid protein monitoring in complex biological fluids. Proc Natl Acad Sci U S A (2005) 1.80
A combinatorial scaffold approach toward kinase-directed heterocycle libraries. J Am Chem Soc (2002) 1.79
Glycogen synthase kinase 3 inhibitors induce the canonical WNT/β-catenin pathway to suppress growth and self-renewal in embryonal rhabdomyosarcoma. Proc Natl Acad Sci U S A (2014) 1.79
Enrichment of cancer cells using aptamers immobilized on a microfluidic channel. Anal Chem (2009) 1.78
A small molecule primes embryonic stem cells for differentiation. Cell Stem Cell (2009) 1.78
A new class of homogeneous nucleic acid probes based on specific displacement hybridization. Nucleic Acids Res (2002) 1.76
Optimization and modifications of aptamers selected from live cancer cell lines. Chembiochem (2007) 1.76
Aptamer-modified gold nanoparticles for colorimetric determination of platelet-derived growth factors and their receptors. Anal Chem (2005) 1.76
Parkinson's disease in China: prevalence in Beijing, Xian, and Shanghai. Lancet (2005) 1.75
Ultrasensitive DNA detection using highly fluorescent bioconjugated nanoparticles. J Am Chem Soc (2003) 1.74
Molecular assembly of an aptamer-drug conjugate for targeted drug delivery to tumor cells. Chembiochem (2009) 1.73
Yeast model uncovers dual roles of mitochondria in action of artemisinin. PLoS Genet (2005) 1.72
Molecular recognition of small-cell lung cancer cells using aptamers. ChemMedChem (2008) 1.71
Aptamers evolved from cultured cancer cells reveal molecular differences of cancer cells in patient samples. Clin Chem (2007) 1.69
TRPM8 mechanism of cold allodynia after chronic nerve injury. J Neurosci (2007) 1.69
The mitochondrial pathway of anesthetic isoflurane-induced apoptosis. J Biol Chem (2009) 1.64
In vivo study of biodistribution and urinary excretion of surface-modified silica nanoparticles. Anal Chem (2008) 1.64
Aptamer-based microfluidic device for enrichment, sorting, and detection of multiple cancer cells. Anal Chem (2009) 1.61
Ca2+/calmodulin-dependent protein kinase IIdelta and protein kinase D overexpression reinforce the histone deacetylase 5 redistribution in heart failure. Circ Res (2008) 1.58
Aptamer-conjugated nanoparticles for selective collection and detection of cancer cells. Anal Chem (2006) 1.58
Association between DNA variant sites in the apolipoprotein A5 gene and coronary heart disease in Chinese. Metabolism (2005) 1.58
Dedifferentiation of lineage-committed cells by a small molecule. J Am Chem Soc (2004) 1.56
DNA aptamer-micelle as an efficient detection/delivery vehicle toward cancer cells. Proc Natl Acad Sci U S A (2009) 1.56
Aptamer-conjugated nanoparticles for the collection and detection of multiple cancer cells. Anal Chem (2007) 1.55
Cancer cell targeting using multiple aptamers conjugated on nanorods. Anal Chem (2008) 1.55
Optimization of dye-doped silica nanoparticles prepared using a reverse microemulsion method. Langmuir (2004) 1.52
Locked nucleic acid molecular beacons. J Am Chem Soc (2005) 1.51
HIF2alpha cooperates with RAS to promote lung tumorigenesis in mice. J Clin Invest (2009) 1.49
Molecular aptamer beacons for real-time protein recognition. Biochem Biophys Res Commun (2002) 1.49
Artemisinin directly targets malarial mitochondria through its specific mitochondrial activation. PLoS One (2010) 1.45
Molecular assembly for high-performance bivalent nucleic acid inhibitor. Proc Natl Acad Sci U S A (2008) 1.44
A small-molecule agonist of the Wnt signaling pathway. Angew Chem Int Ed Engl (2005) 1.44
DNA-functionalized nanotube membranes with single-base mismatch selectivity. Science (2004) 1.44
Aptamer-enabled efficient isolation of cancer cells from whole blood using a microfluidic device. Anal Chem (2012) 1.44
Isoflurane-induced caspase-3 activation is dependent on cytosolic calcium and can be attenuated by memantine. J Neurosci (2008) 1.44
Carbon nanotube-quenched fluorescent oligonucleotides: probes that fluoresce upon hybridization. J Am Chem Soc (2008) 1.43
Multicolor FRET silica nanoparticles by single wavelength excitation. Nano Lett (2006) 1.40
Aptamer switch probe based on intramolecular displacement. J Am Chem Soc (2008) 1.40
Retracted Comparison of the sagittal profiles among thoracic idiopathic scoliosis patients with different Cobb angles and growth potentials. J Orthop Surg Res (2014) 1.39
Bioconjugated nanoparticles for DNA protection from cleavage. J Am Chem Soc (2003) 1.39
Anesthetic sevoflurane causes neurotoxicity differently in neonatal naïve and Alzheimer disease transgenic mice. Anesthesiology (2010) 1.38
Selective photothermal therapy for mixed cancer cells using aptamer-conjugated nanorods. Langmuir (2008) 1.37
DNA aptamers as molecular probes for colorectal cancer study. PLoS One (2010) 1.36
Uptake of silica-coated nanoparticles by HeLa cells. J Nanosci Nanotechnol (2005) 1.36
Assembly of aptamer switch probes and photosensitizer on gold nanorods for targeted photothermal and photodynamic cancer therapy. ACS Nano (2012) 1.32
Generating aptamers for recognition of virus-infected cells. Clin Chem (2009) 1.31
Loss of JAK2 regulation via a heterodimeric VHL-SOCS1 E3 ubiquitin ligase underlies Chuvash polycythemia. Nat Med (2011) 1.31
Self-assembled, aptamer-tethered DNA nanotrains for targeted transport of molecular drugs in cancer theranostics. Proc Natl Acad Sci U S A (2013) 1.29
Compatibility art of traditional Chinese medicine: from the perspective of herb pairs. J Ethnopharmacol (2012) 1.29
[A study on the differential diagnosis of ciliated epithelial cells from Lophomonas blattarum in bronchoalveolar lavage fluid]. Zhonghua Jie He He Hu Xi Za Zhi (2013) 1.27
Genome-wide mapping of SMAD target genes reveals the role of BMP signaling in embryonic stem cell fate determination. Genome Res (2009) 1.27
Noncanonical self-assembly of multifunctional DNA nanoflowers for biomedical applications. J Am Chem Soc (2013) 1.26
Study of the molecular recognition of aptamers selected through ovarian cancer cell-SELEX. PLoS One (2010) 1.26
In vivo near-infrared fluorescence imaging of cancer with nanoparticle-based probes. Wiley Interdiscip Rev Nanomed Nanobiotechnol (2010) 1.26
Inhibition of histone deacetylase activity induces developmental plasticity in oligodendrocyte precursor cells. Proc Natl Acad Sci U S A (2007) 1.26
Synthetic DNA aptamers to detect protein molecular variants in a high-throughput fluorescence quenching assay. Chembiochem (2003) 1.26
Yeast AMID homologue Ndi1p displays respiration-restricted apoptotic activity and is involved in chronological aging. Mol Biol Cell (2006) 1.24
Regulation of singlet oxygen generation using single-walled carbon nanotubes. J Am Chem Soc (2008) 1.23
Recognition of subtype non-small cell lung cancer by DNA aptamers selected from living cells. Analyst (2009) 1.22
Identification of RING finger protein 4 (RNF4) as a modulator of DNA demethylation through a functional genomics screen. Proc Natl Acad Sci U S A (2010) 1.22
Fighting fire with fire: poisonous Chinese herbal medicine for cancer therapy. J Ethnopharmacol (2012) 1.22
Collection of trace amounts of DNA/mRNA molecules using genomagnetic nanocapturers. Anal Chem (2003) 1.21
Aptamer-nanoparticle strip biosensor for sensitive detection of cancer cells. Anal Chem (2009) 1.20
FloDots: luminescent nanoparticles. Anal Bioanal Chem (2006) 1.20
Identification of small-molecule inducers of pancreatic beta-cell expansion. Proc Natl Acad Sci U S A (2009) 1.20