Published in Curr Opin Struct Biol on November 25, 2008
Microbial degradation of aromatic compounds - from one strategy to four. Nat Rev Microbiol (2011) 2.31
Trapping and spectroscopic characterization of an FeIII-superoxo intermediate from a nonheme mononuclear iron-containing enzyme. Proc Natl Acad Sci U S A (2010) 1.57
Evidence for a ferryl intermediate in a heme-based dioxygenase. Proc Natl Acad Sci U S A (2009) 1.13
Ring-cleaving dioxygenases with a cupin fold. Appl Environ Microbiol (2012) 1.06
Metallation and mismetallation of iron and manganese proteins in vitro and in vivo: the class I ribonucleotide reductases as a case study. Metallomics (2012) 1.01
Substrate-mediated oxygen activation by homoprotocatechuate 2,3-dioxygenase: intermediates formed by a tyrosine 257 variant. Biochemistry (2012) 0.97
Structural basis for the role of tyrosine 257 of homoprotocatechuate 2,3-dioxygenase in substrate and oxygen activation. Biochemistry (2012) 0.94
Mechanism of S-oxygenation by a cysteine dioxygenase model complex. J Phys Chem A (2011) 0.90
Comparative genomic analysis of four representative plant growth-promoting rhizobacteria in Pseudomonas. BMC Genomics (2013) 0.89
Characterization of recombinant Beta vulgaris 4,5-DOPA-extradiol-dioxygenase active in the biosynthesis of betalains. Planta (2012) 0.87
Topological variation in the evolution of new reactions in functionally diverse enzyme superfamilies. Curr Opin Struct Biol (2011) 0.86
A two-electron-shell game: intermediates of the extradiol-cleaving catechol dioxygenases. J Biol Inorg Chem (2014) 0.84
Structural, spectroscopic, and electrochemical properties of nonheme Fe(II)-hydroquinonate complexes: synthetic models of hydroquinone dioxygenases. Dalton Trans (2012) 0.84
Structural characterization of 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA) from Sphingobium chlorophenolicum, a new type of aromatic ring-cleavage enzyme. Mol Microbiol (2013) 0.83
Substrate binding mechanism of a type I extradiol dioxygenase. J Biol Chem (2010) 0.82
Crystal structures of alkylperoxo and anhydride intermediates in an intradiol ring-cleaving dioxygenase. Proc Natl Acad Sci U S A (2014) 0.81
A synthetic model of the putative Fe(II)-iminobenzosemiquinonate intermediate in the catalytic cycle of o-aminophenol dioxygenases. J Am Chem Soc (2012) 0.81
Oxidative Cyclization in Natural Product Biosynthesis. Chem Rev (2016) 0.81
Structural Basis for Substrate and Oxygen Activation in Homoprotocatechuate 2,3-Dioxygenase: Roles of Conserved Active Site Histidine 200. Biochemistry (2015) 0.80
Rate-Determining Attack on Substrate Precedes Rieske Cluster Oxidation during Cis-Dihydroxylation by Benzoate Dioxygenase. Biochemistry (2015) 0.80
A preliminary crystallographic study of recombinant NicX, an Fe(2+)-dependent 2,5-dihydroxypyridine dioxygenase from Pseudomonas putida KT2440. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.79
Crystal structure and functional analysis of the extradiol dioxygenase LapB from a long-chain alkylphenol degradation pathway in Pseudomonas. J Biol Chem (2009) 0.79
Dioxygen reactivity of biomimetic Fe(II) complexes with noninnocent catecholate, o-aminophenolate, and o-phenylenediamine ligands. Inorg Chem (2014) 0.77
Finding molecular dioxygen tunnels in homoprotocatechuate 2,3-dioxygenase: implications for different reactivity of identical subunits. Eur Biophys J (2009) 0.77
Synthetic, spectroscopic, and DFT studies of iron complexes with iminobenzo(semi)quinone ligands: implications for o-aminophenol dioxygenases. Chemistry (2013) 0.77
Molecular mechanism of strict substrate specificity of an extradiol dioxygenase, DesB, derived from Sphingobium sp. SYK-6. PLoS One (2014) 0.77
In vivo self-hydroxylation of an iron-substituted manganese-dependent extradiol cleaving catechol dioxygenase. J Biol Inorg Chem (2011) 0.76
The alkenyl migration mechanism catalyzed by extradiol dioxygenases: a hybrid DFT study. J Biol Inorg Chem (2012) 0.76
NO binding to Mn-substituted homoprotocatechuate 2,3-dioxygenase: relationship to O₂ reactivity. J Biol Inorg Chem (2013) 0.75
Enzyme Substrate Complex of the H200C Variant of Homoprotocatechuate 2,3-Dioxygenase: Mössbauer and Computational Studies. Inorg Chem (2016) 0.75
Fe(II) complexes that mimic the active site structure of acetylacetone dioxygenase: O2 and NO reactivity. Inorg Chem (2012) 0.75
O2 Activation by Non-Heme Iron Enzymes. Biochemistry (2016) 0.75
Crystallization and preliminary crystallographic analysis of manganese(II)-dependent 2,3-dihydroxybiphenyl 1,2-dioxygenase from Bacillus sp. JF8. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.75
3,4-Dihydroxyphenylacetate 2,3-dioxygenase from Pseudomonas aeruginosa: An Fe(II)-containing enzyme with fast turnover. PLoS One (2017) 0.75
Oxygen activation by mononuclear nonheme iron dioxygenases involved in the degradation of aromatics. J Biol Inorg Chem (2017) 0.75
Structure and Spectroscopy of Alkene-Cleaving Dioxygenases Containing an Atypically Coordinated Non-Heme Iron Center. Biochemistry (2017) 0.75
Global stability of an α-ketoglutarate-dependent dioxygenase (TauD) and its related complexes. Biochim Biophys Acta (2017) 0.75
Thiol dioxygenase turnover yields benzothiazole products from 2-mercaptoaniline and O2-dependent oxidation of primary alcohols. Arch Biochem Biophys (2017) 0.75
Synthesis, X-ray Structures, Electronic Properties, and O2/NO Reactivities of Thiol Dioxygenase Active-Site Models. Inorg Chem (2016) 0.75
Oxygen activation by mononuclear Mn, Co, and Ni centers in biology and synthetic complexes. J Biol Inorg Chem (2016) 0.75
Exploring substrate binding in homoprotocatechuate 2,3-dioxygenase using isothermal titration calorimetry. J Biol Inorg Chem (2012) 0.75
Dioxygen activation at mononuclear nonheme iron active sites: enzymes, models, and intermediates. Chem Rev (2004) 6.11
Non-heme Fe(IV)-oxo intermediates. Acc Chem Res (2007) 3.55
Crystal structure of naphthalene dioxygenase: side-on binding of dioxygen to iron. Science (2003) 3.07
Crystal structures of Fe2+ dioxygenase superoxo, alkylperoxo, and bound product intermediates. Science (2007) 3.03
The 2-His-1-carboxylate facial triad: a versatile platform for dioxygen activation by mononuclear non-heme iron(II) enzymes. J Biol Inorg Chem (2005) 2.82
Crystal structure of the biphenyl-cleaving extradiol dioxygenase from a PCB-degrading pseudomonad. Science (1995) 2.68
Finding intermediates in the O2 activation pathways of non-heme iron oxygenases. Acc Chem Res (2007) 2.64
Versatility of biological non-heme Fe(II) centers in oxygen activation reactions. Nat Chem Biol (2008) 2.64
The ins and outs of ring-cleaving dioxygenases. Crit Rev Biochem Mol Biol (2006) 2.36
Three-dimensional structures of free form and two substrate complexes of an extradiol ring-cleavage type dioxygenase, the BphC enzyme from Pseudomonas sp. strain KKS102. J Mol Biol (1996) 1.98
Binding of 17O-labeled substrate and inhibitors to protocatechuate 4,5-dioxygenase-nitrosyl complex. Evidence for direct substrate binding to the active site Fe2+ of extradiol dioxygenases. J Biol Chem (1986) 1.86
Crystallographic comparison of manganese- and iron-dependent homoprotocatechuate 2,3-dioxygenases. J Bacteriol (2004) 1.84
Direct spectroscopic evidence for a high-spin Fe(IV) intermediate in tyrosine hydroxylase. J Am Chem Soc (2007) 1.80
X-ray absorption spectroscopic studies of the Fe(II) active site of catechol 2,3-dioxygenase. Implications for the extradiol cleavage mechanism. Biochemistry (1995) 1.70
Spectroscopic and computational evaluation of the structure of the high-spin Fe(IV)-oxo intermediates in taurine: alpha-ketoglutarate dioxygenase from Escherichia coli and its His99Ala ligand variant. J Am Chem Soc (2007) 1.68
Non-heme iron-dependent dioxygenases: unravelling catalytic mechanisms for complex enzymatic oxidations. Curr Opin Chem Biol (2008) 1.60
Aromatic ring cleavage by homoprotocatechuate 2,3-dioxygenase: role of His200 in the kinetics of interconversion of reaction cycle intermediates. Biochemistry (2005) 1.57
Crystal structures of the reaction intermediate and its homologue of an extradiol-cleaving catecholic dioxygenase. J Mol Biol (2002) 1.50
VTVH-MCD and DFT studies of thiolate bonding to [FeNO]7/[FeO2]8 complexes of isopenicillin N synthase: substrate determination of oxidase versus oxygenase activity in nonheme Fe enzymes. J Am Chem Soc (2007) 1.50
Single-turnover kinetics of homoprotocatechuate 2,3-dioxygenase. Biochemistry (2004) 1.48
Swapping metals in Fe- and Mn-dependent dioxygenases: evidence for oxygen activation without a change in metal redox state. Proc Natl Acad Sci U S A (2008) 1.47
Definitive evidence for monoanionic binding of 2,3-dihydroxybiphenyl to 2,3-dihydroxybiphenyl 1,2-dioxygenase from UV resonance Raman spectroscopy, UV/Vis absorption spectroscopy, and crystallography. J Am Chem Soc (2002) 1.45
Mechanism for catechol ring-cleavage by non-heme iron extradiol dioxygenases. J Am Chem Soc (2004) 1.39
Radical intermediates in monooxygenase reactions of rieske dioxygenases. J Am Chem Soc (2007) 1.20
A density functional investigation of the extradiol cleavage mechanism in non-heme iron catechol dioxygenases. J Biol Inorg Chem (2003) 1.19
Hydrogen peroxide dependent cis-dihydroxylation of benzoate by fully oxidized benzoate 1,2-dioxygenase. Biochemistry (2007) 1.16
Extradiol oxidative cleavage of catechols by ferrous and ferric complexes of 1,4,7-triazacyclononane: insight into the mechanism of the extradiol catechol dioxygenases. J Am Chem Soc (2001) 1.09
The mechanism for isopenicillin N synthase from density-functional modeling highlights the similarities with other enzymes in the 2-His-1-carboxylate family. Biochemistry (2007) 1.08
Acid-base catalysis in the extradiol catechol dioxygenase reaction mechanism: site-directed mutagenesis of His-115 and His-179 in Escherichia coli 2,3-dihydroxyphenylpropionate 1,2-dioxygenase (MhpB). Biochemistry (2004) 1.08
Quantum chemical studies of dioxygen activation by mononuclear non-heme iron enzymes with the 2-His-1-carboxylate facial triad. Dalton Trans (2004) 1.02
The role of histidine 200 in MndD, the Mn(II)-dependent 3,4-dihydroxyphenylacetate 2,3-dioxygenase from Arthrobacter globiformis CM-2, a site-directed mutagenesis study. J Biol Inorg Chem (2005) 0.99
Conversion of extradiol aromatic ring-cleaving homoprotocatechuate 2,3-dioxygenase into an intradiol cleaving enzyme. J Am Chem Soc (2003) 0.96
Theoretical study of the catalytic reaction mechanism of MndD. J Biol Inorg Chem (2006) 0.92
Interactions of isopenicillin N synthase with cyclopropyl-containing substrate analogues reveal new mechanistic insight. Biochemistry (2007) 0.86
Evidence from mechanistic probes for distinct hydroperoxide rearrangement mechanisms in the intradiol and extradiol catechol dioxygenases. J Am Chem Soc (2008) 0.81
A comparison of the reaction mechanisms of iron- and manganese-containing 2,3-HPCD: an important spin transition for manganese. J Biol Inorg Chem (2008) 0.81
Directed evolution of a non-heme-iron-dependent extradiol catechol dioxygenase: identification of mutants with intradiol oxidative cleavage activity. Chembiochem (2006) 0.80
Single-turnover kinetics of 2,3-dihydroxybiphenyl 1,2-dioxygenase reacting with 3-formylcatechol. Biochem Biophys Res Commun (2005) 0.79