Published in Cancer Res on November 15, 2008
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy (2016) 7.05
The double-edged sword of autophagy modulation in cancer. Clin Cancer Res (2009) 5.46
Autophagy modulation as a potential therapeutic target for diverse diseases. Nat Rev Drug Discov (2012) 5.26
Autophagy: assays and artifacts. J Pathol (2010) 3.45
Targeting the prodeath and prosurvival functions of autophagy as novel therapeutic strategies in cancer. Autophagy (2010) 2.62
Role of the microenvironment in the pathogenesis and treatment of hepatocellular carcinoma. Gastroenterology (2013) 2.21
Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells. Autophagy (2009) 2.09
The decreased expression of Beclin-1 correlates with progression to esophageal adenocarcinoma: the role of deoxycholic acid. Am J Physiol Gastrointest Liver Physiol (2012) 1.60
Autophagy as a target for cancer therapy: new developments. Cancer Manag Res (2012) 1.44
Autophagy in nonalcoholic steatohepatitis. Expert Rev Gastroenterol Hepatol (2011) 1.32
Anti-tumoral action of cannabinoids on hepatocellular carcinoma: role of AMPK-dependent activation of autophagy. Cell Death Differ (2011) 1.32
Beclin 1 over- and underexpression in colorectal cancer: distinct patterns relate to prognosis and tumour hypoxia. Br J Cancer (2010) 1.30
Autophagy and tumorigenesis. Semin Immunopathol (2010) 1.26
Aberrant expression of Beclin-1 and LC3 correlates with poor prognosis of human hypopharyngeal squamous cell carcinoma. PLoS One (2013) 1.16
Autophagy suppresses tumorigenesis of hepatitis B virus-associated hepatocellular carcinoma through degradation of microRNA-224. Hepatology (2013) 1.12
Liver autophagy: much more than just taking out the trash. Nat Rev Gastroenterol Hepatol (2013) 1.05
Expression of nicotinamide N-methyltransferase in hepatocellular carcinoma is associated with poor prognosis. J Exp Clin Cancer Res (2009) 1.02
Prognostic impact of Beclin 1, p62/sequestosome 1 and LC3 protein expression in colon carcinomas from patients receiving 5-fluorouracil as adjuvant chemotherapy. Cancer Biol Ther (2012) 1.01
MicroRNA-100 promotes the autophagy of hepatocellular carcinoma cells by inhibiting the expression of mTOR and IGF-1R. Oncotarget (2014) 0.99
Decreased expression of Beclin 1 correlates closely with Bcl-xL expression and poor prognosis of ovarian carcinoma. PLoS One (2013) 0.96
A novel ATG4B antagonist inhibits autophagy and has a negative impact on osteosarcoma tumors. Autophagy (2014) 0.94
Autophagy and cancer. Cells (2012) 0.94
Autophagy and apoptosis in liver injury. Cell Cycle (2015) 0.92
Obesity, autophagy and the pathogenesis of liver and pancreatic cancers. J Gastroenterol Hepatol (2012) 0.91
Autophagy may promote carcinoma cell invasion and correlate with poor prognosis in cholangiocarcinoma. Int J Clin Exp Pathol (2014) 0.89
Regulation of Liver Metabolism by Autophagy. Gastroenterology (2015) 0.89
Chloroquine and hydroxychloroquine for cancer therapy. Mol Cell Oncol (2014) 0.88
Autophagy modulation as a potential therapeutic target for liver diseases. J Clin Exp Hepatol (2014) 0.87
Contributions of metabolic dysregulation and inflammation to nonalcoholic steatohepatitis, hepatic fibrosis, and cancer. Curr Opin Oncol (2014) 0.87
Autophagy and non-alcoholic fatty liver disease. Biomed Res Int (2014) 0.87
Potent antitumor activity of oncolytic adenovirus expressing Beclin-1 via induction of autophagic cell death in leukemia. Oncotarget (2013) 0.86
High expression of 5-hydroxymethylcytosine and isocitrate dehydrogenase 2 is associated with favorable prognosis after curative resection of hepatocellular carcinoma. J Exp Clin Cancer Res (2014) 0.86
Autophagy-based survival prognosis in human colorectal carcinoma. Oncotarget (2015) 0.86
Promoting colonization in metastatic HCC cells by modulation of autophagy. PLoS One (2013) 0.85
Phosphorylated AKT inhibits the apoptosis induced by DRAM-mediated mitophagy in hepatocellular carcinoma by preventing the translocation of DRAM to mitochondria. Cell Death Dis (2014) 0.85
Inhibition of autophagy promotes metastasis and glycolysis by inducing ROS in gastric cancer cells. Oncotarget (2015) 0.84
Impaired autophagy response in human hepatocellular carcinoma. Exp Mol Pathol (2013) 0.84
Autophagy enhances hepatocellular carcinoma progression by activation of mitochondrial β-oxidation. J Gastroenterol (2013) 0.83
Active autophagy in the tumor microenvironment: A novel mechanism for cancer metastasis. Oncol Lett (2012) 0.82
α-Fetoprotein promoter-driven Cre/LoxP-switched RNA interference for hepatocellular carcinoma tissue-specific target therapy. PLoS One (2013) 0.81
Hepatocellular carcinoma mouse models: Hepatitis B virus-associated hepatocarcinogenesis and haploinsufficient tumor suppressor genes. World J Gastroenterol (2016) 0.81
Autophagy: a primer for the gastroenterologist/hepatologist. Can J Gastroenterol (2011) 0.80
miR-Let7A Modulates Autophagy Induction in LPS-Activated Microglia. Exp Neurobiol (2015) 0.79
Autophagy and microRNA in hepatitis B virus-related hepatocellular carcinoma. World J Gastroenterol (2016) 0.78
Overexpression of hnRNPC2 induces multinucleation by repression of Aurora B in hepatocellular carcinoma cells. Oncol Lett (2013) 0.78
mda-7/IL-24 mediates cancer cell-specific death via regulation of miR-221 and the beclin-1 axis. Cancer Res (2016) 0.77
Targeting metabolism and autophagy in the context of haematologic malignancies. Int J Cell Biol (2012) 0.77
The expression of LC-3 is related to tumor suppression through angiogenesis in esophageal cancer. Med Oncol (2013) 0.77
The Role of Autophagy in Hepatocellular Carcinoma. Int J Mol Sci (2015) 0.77
LOXL4 is downregulated in hepatocellular carcinoma with a favorable prognosis. Int J Clin Exp Pathol (2015) 0.77
Galectin-3 and Beclin1/Atg6 genes in human cancers: using cDNA tissue panel, qRT-PCR, and logistic regression model to identify cancer cell biomarkers. PLoS One (2011) 0.76
Chloroquine enhances the efficacy of cisplatin by suppressing autophagy in human adrenocortical carcinoma treatment. Drug Des Devel Ther (2016) 0.76
Expression of autophagy-related protein Beclin-1 in malignant canine mammary tumors. BMC Vet Res (2013) 0.76
Function of Autophagy in Nonalcoholic Fatty Liver Disease. Dig Dis Sci (2016) 0.76
Antibody-based proteomics to identify an apoptosis signature for early recurrence of hepatocellular carcinoma. Clin Proteomics (2016) 0.75
P300/CBP-associated factor (PCAF) inhibits the growth of hepatocellular carcinoma by promoting cell autophagy. Cell Death Dis (2016) 0.75
Expressions and clinical significance of autophagy-related markers Beclin1, LC3, and EGFR in human cervical squamous cell carcinoma. Onco Targets Ther (2015) 0.75
Co-Targeting IGF-1R and Autophagy Enhances the Effects of Cell Growth Suppression and Apoptosis Induced by the IGF-1R Inhibitor NVP-AEW541 in Triple-Negative Breast Cancer Cells. PLoS One (2017) 0.75
Induction of epithelial-mesenchymal transition (EMT) by Beclin 1 knockdown via posttranscriptional upregulation of ZEB1 in thyroid cancer cells. Oncotarget (2016) 0.75
CoQ10 Deficiency May Indicate Mitochondrial Dysfunction in Cr(VI) Toxicity. Int J Mol Sci (2017) 0.75
miR-140-5p attenuates chemotherapeutic drug-induced cell death by regulating autophagy through inositol 1,4,5-trisphosphate kinase 2 (IP3k2) in human osteosarcoma cells. Biosci Rep (2016) 0.75
Characterization of apoptosis and autophagy through Bcl-2 and Beclin-1 immunoexpression in gestational trophoblastic disease. Iran J Reprod Med (2015) 0.75
Expression of Beclin Family Proteins Is Associated with Tumor Progression in Oral Cancer. PLoS One (2015) 0.75
Beclin 1 expression is associated with the occurrence and development of esophageal squamous cell carcinoma. Oncol Lett (2017) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
AMP-activated protein kinase induces a p53-dependent metabolic checkpoint. Mol Cell (2005) 11.19
Immunogenicity of induced pluripotent stem cells. Nature (2011) 7.31
MicroRNA expression, survival, and response to interferon in liver cancer. N Engl J Med (2009) 6.13
p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression. Nat Cell Biol (2004) 5.82
Intratumoral balance of regulatory and cytotoxic T cells is associated with prognosis of hepatocellular carcinoma after resection. J Clin Oncol (2007) 5.28
Serum DKK1 as a protein biomarker for the diagnosis of hepatocellular carcinoma: a large-scale, multicentre study. Lancet Oncol (2012) 4.21
p53 gain-of-function cancer mutants induce genetic instability by inactivating ATM. Nat Cell Biol (2007) 3.86
Plasma microRNA panel to diagnose hepatitis B virus-related hepatocellular carcinoma. J Clin Oncol (2011) 3.80
Real-time observation of transcription initiation and elongation on an endogenous yeast gene. Science (2011) 3.67
(E)-1-{4-[Bis(4-meth-oxy-phen-yl)meth-yl]piperazin-1-yl}-3-(4-fluoro-phen-yl)prop-2-en-1-one. Acta Crystallogr Sect E Struct Rep Online (2011) 3.63
Overexpression of PD-L1 significantly associates with tumor aggressiveness and postoperative recurrence in human hepatocellular carcinoma. Clin Cancer Res (2009) 3.39
Functional analysis of the roles of posttranslational modifications at the p53 C terminus in regulating p53 stability and activity. Mol Cell Biol (2005) 2.72
Fibroblast growth factor 21 levels are increased in nonalcoholic fatty liver disease patients and are correlated with hepatic triglyceride. J Hepatol (2010) 2.65
Involvement of receptor-interacting protein 2 in innate and adaptive immune responses. Nature (2002) 2.60
A decade's studies on metastasis of hepatocellular carcinoma. J Cancer Res Clin Oncol (2003) 2.50
TRPC channels promote cerebellar granule neuron survival. Nat Neurosci (2007) 2.47
Randomized, multicenter, open-label study of oxaliplatin plus fluorouracil/leucovorin versus doxorubicin as palliative chemotherapy in patients with advanced hepatocellular carcinoma from Asia. J Clin Oncol (2013) 2.44
Single β-actin mRNA detection in neurons reveals a mechanism for regulating its translatability. Science (2014) 2.23
Molecular symmetry in mitochondrial cardiolipins. Chem Phys Lipids (2005) 2.23
Unexpected role of interferon-γ in regulating neuronal connectivity and social behaviour. Nature (2016) 2.21
Modeling disease in human ESCs using an efficient BAC-based homologous recombination system. Cell Stem Cell (2010) 2.19
Ser18 and 23 phosphorylation is required for p53-dependent apoptosis and tumor suppression. EMBO J (2006) 2.12
The Effect of Erythropoietin-Stimulating Agents on Health-Related Quality of Life in Anemia of Chronic Kidney Disease: A Systematic Review and Meta-analysis. Ann Intern Med (2016) 2.09
Formation of large voids in the amorphous phase-change memory Ge2Sb2Te5 alloy. Phys Rev Lett (2009) 2.06
Cytotoxicity effects of graphene and single-wall carbon nanotubes in neural phaeochromocytoma-derived PC12 cells. ACS Nano (2010) 2.05
Cell type- and promoter-specific roles of Ser18 phosphorylation in regulating p53 responses. J Biol Chem (2003) 2.02
Cooperative assembly and dynamic disassembly of MDA5 filaments for viral dsRNA recognition. Proc Natl Acad Sci U S A (2011) 1.99
A novel nuclear factor-kappaB gene signature is differentially expressed in head and neck squamous cell carcinomas in association with TP53 status. Clin Cancer Res (2007) 1.96
Study of severe and rare complications of transarterial chemoembolization (TACE) for liver cancer. Eur J Radiol (2006) 1.95
An NMR approach to structural proteomics. Proc Natl Acad Sci U S A (2002) 1.95
Incidence of second malignancies among patients treated with proton versus photon radiation. Int J Radiat Oncol Biol Phys (2013) 1.89
Positive serum hepatitis B e antigen is associated with higher risk of early recurrence and poorer survival in patients after curative resection of hepatitis B-related hepatocellular carcinoma. J Hepatol (2007) 1.86
Circulating stem cell-like epithelial cell adhesion molecule-positive tumor cells indicate poor prognosis of hepatocellular carcinoma after curative resection. Hepatology (2013) 1.84
A comparison of chemoembolization combination with and without radiotherapy for unresectable hepatocellular carcinoma. Cancer J (2004) 1.84
Thermally driven crossover from indirect toward direct bandgap in 2D semiconductors: MoSe2 versus MoS2. Nano Lett (2012) 1.82
Targeting autophagy enhances sorafenib lethality for hepatocellular carcinoma via ER stress-related apoptosis. Autophagy (2011) 1.81
Serum and urine metabolite profiling reveals potential biomarkers of human hepatocellular carcinoma. Mol Cell Proteomics (2011) 1.81
Phosphine-triggered synthesis of functionalized cyclic compounds. Chem Soc Rev (2008) 1.80
Response of soil respiration to soil temperature and moisture in a 50-year-old oriental arborvitae plantation in China. PLoS One (2011) 1.80
Even-skipped, acting as a repressor, regulates axonal projections in Drosophila. Development (2003) 1.77
Proteomic fingerprints for potential application to early diagnosis of severe acute respiratory syndrome. Clin Chem (2004) 1.76
Retracted Carbon nanotubes are able to penetrate plant seed coat and dramatically affect seed germination and plant growth. ACS Nano (2009) 1.73
Diagnosis and treatment of hepatic angiomyolipoma in 26 cases. World J Gastroenterol (2003) 1.71
A physiologic role for testosterone in limiting estrogenic stimulation of the breast. Menopause (2003) 1.71
A novel loss-of-function DDAH1 promoter polymorphism is associated with increased susceptibility to thrombosis stroke and coronary heart disease. Circ Res (2010) 1.70
DAB2IP coordinates both PI3K-Akt and ASK1 pathways for cell survival and apoptosis. Proc Natl Acad Sci U S A (2009) 1.69
Coexistence of hepatitis B surface antigen (HBsAg) and heterologous subtype-specific antibodies to HBsAg among patients with chronic hepatitis B virus infection. Clin Infect Dis (2007) 1.69
A comparison of treatment combinations with and without radiotherapy for hepatocellular carcinoma with portal vein and/or inferior vena cava tumor thrombus. Int J Radiat Oncol Biol Phys (2005) 1.66
A technique for retrograde intubation in mice. Lab Anim (NY) (2006) 1.65
Mutation of mouse p53 Ser23 and the response to DNA damage. Mol Cell Biol (2002) 1.65
Consideration of the role of radiotherapy for unresectable intrahepatic cholangiocarcinoma: a retrospective analysis of 75 patients. Cancer J (2006) 1.65
A DNA nanostructure platform for directed assembly of synthetic vaccines. Nano Lett (2012) 1.64
Targeted disruption of NBS1 reveals its roles in mouse development and DNA repair. EMBO J (2002) 1.64
Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma. Nat Genet (2012) 1.64
Phosphorylation site interdependence of human p53 post-translational modifications in response to stress. J Biol Chem (2003) 1.63
Essential roles of the kappa light chain intronic enhancer and 3' enhancer in kappa rearrangement and demethylation. Nat Immunol (2002) 1.63
Evaluation of the biocompatibility of a chitosan scaffold in mice. J Biomed Mater Res (2002) 1.62
Beneficial effect of taurine on testicular ischemia-reperfusion injury in rats. Urology (2007) 1.62
Postoperative interferon alpha treatment postponed recurrence and improved overall survival in patients after curative resection of HBV-related hepatocellular carcinoma: a randomized clinical trial. J Cancer Res Clin Oncol (2006) 1.60
Cardiolipin affects the supramolecular organization of ATP synthase in mitochondria. Biophys J (2011) 1.57
Phosphorylation stabilizes Nanog by promoting its interaction with Pin1. Proc Natl Acad Sci U S A (2010) 1.57