PubRank

G Waksman

Author PubWeight™ 104.98‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation. EMBO J 1998 7.13
2 Major domain swiveling revealed by the crystal structures of complexes of E. coli Rep helicase bound to single-stranded DNA and ADP. Cell 1997 4.71
3 Structural basis of chaperone function and pilus biogenesis. Science 1999 3.69
4 Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2. Proc Natl Acad Sci U S A 1997 3.66
5 Structure of the DNA binding domain of E. coli SSB bound to ssDNA. Nat Struct Biol 2000 3.34
6 The biology and enzymology of protein N-myristoylation. J Biol Chem 2001 3.14
7 Crystal structure of the hexameric traffic ATPase of the Helicobacter pylori type IV secretion system. Mol Cell 2000 2.74
8 Synthetic protein transduction domains: enhanced transduction potential in vitro and in vivo. Cancer Res 2001 2.54
9 Crystal structure of the homo-tetrameric DNA binding domain of Escherichia coli single-stranded DNA-binding protein determined by multiwavelength x-ray diffraction on the selenomethionyl protein at 2.9-A resolution. Proc Natl Acad Sci U S A 1997 2.23
10 BH3 domain of BAD is required for heterodimerization with BCL-XL and pro-apoptotic activity. J Biol Chem 1997 2.23
11 Loss of fibroblast growth factor receptor 2 ligand-binding specificity in Apert syndrome. Proc Natl Acad Sci U S A 2000 2.13
12 Mutagenesis of the BH3 domain of BAX identifies residues critical for dimerization and killing. Mol Cell Biol 1998 2.05
13 PapD-like chaperones provide the missing information for folding of pilin proteins. Proc Natl Acad Sci U S A 2000 1.98
14 Crystal structure of the large fragment of Thermus aquaticus DNA polymerase I at 2.5-A resolution: structural basis for thermostability. Proc Natl Acad Sci U S A 1995 1.94
15 Comparisons between the structures of HCV and Rep helicases reveal structural similarities between SF1 and SF2 super-families of helicases. Protein Sci 1998 1.93
16 Crystal structures of the Klenow fragment of Thermus aquaticus DNA polymerase I complexed with deoxyribonucleoside triphosphates. Protein Sci 1998 1.90
17 Structural basis of the interaction of the pyelonephritic E. coli adhesin to its human kidney receptor. Cell 2001 1.79
18 Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation. Proc Natl Acad Sci U S A 1999 1.67
19 Hematopoietic malignancies demonstrate loss-of-function mutations of BAX. Blood 1998 1.61
20 Structural basis for Syk tyrosine kinase ubiquity in signal transduction pathways revealed by the crystal structure of its regulatory SH2 domains bound to a dually phosphorylated ITAM peptide. J Mol Biol 1998 1.60
21 Nucleotide sequence of a gene encoding corn ribulose-1,5-bisphosphate carboxylase/oxygenase small subunit (rbcs). Nucleic Acids Res 1987 1.53
22 Chaperone-assisted pilus assembly and bacterial attachment. Curr Opin Struct Biol 2000 1.42
23 Mutations in GJB6 cause hidrotic ectodermal dysplasia. Nat Genet 2000 1.42
24 Crystal structures of a ddATP-, ddTTP-, ddCTP, and ddGTP- trapped ternary complex of Klentaq1: insights into nucleotide incorporation and selectivity. Protein Sci 2001 1.40
25 FGF binding and FGF receptor activation by synthetic heparan-derived di- and trisaccharides. Science 1995 1.38
26 Structure of N-myristoyltransferase with bound myristoylCoA and peptide substrate analogs. Nat Struct Biol 1998 1.27
27 Investigation of phosphotyrosine recognition by the SH2 domain of the Src kinase. J Mol Biol 1999 1.24
28 Calorimetric investigation of proton linkage by monitoring both the enthalpy and association constant of binding: application to the interaction of the Src SH2 domain with a high-affinity tyrosyl phosphopeptide. Biochemistry 1998 1.21
29 Crystal structure of enteropeptidase light chain complexed with an analog of the trypsinogen activation peptide. J Mol Biol 1999 1.19
30 Heparin-induced self-association of fibroblast growth factor-2. Evidence for two oligomerization processes. J Biol Chem 1997 1.19
31 Structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoylCoA and peptide provide insights about substrate recognition and catalysis. Biochemistry 2001 1.15
32 Thermodynamic study of the binding of the tandem-SH2 domain of the Syk kinase to a dually phosphorylated ITAM peptide: evidence for two conformers. Biochemistry 1999 1.15
33 Unexpected crucial role of residue 225 in serine proteases. Proc Natl Acad Sci U S A 1999 1.11
34 The structure of myristoyl-CoA:protein N-myristoyltransferase. Biochim Biophys Acta 1999 1.08
35 Nucleotide sequence of a cDNA encoding the ribulose-1,5-bisphosphate carboxylase/oxygenase from sunflower (Helianthus annuus). Nucleic Acids Res 1987 1.07
36 Probing the "two-pronged plug two-holed socket" model for the mechanism of binding of the Src SH2 domain to phosphotyrosyl peptides: a thermodynamic study. Biochemistry 1998 1.05
37 Fusion of a cleavable signal peptide to the ectodomain of neutral endopeptidase (EC 3.4.24.11) results in the secretion of an active enzyme in COS-1 cells. J Biol Chem 1989 1.05
38 Autoradiographic comparison of the distribution of the neutral endopeptidase "enkephalinase" and of mu and delta opioid receptors in rat brain. Proc Natl Acad Sci U S A 1986 1.04
39 Crystallization of DsbA, an Escherichia coli protein required for disulphide bond formation in vivo. J Mol Biol 1993 1.02
40 Structural biology of bacterial secretion systems in gram-negative pathogens--potential for new drug targets. Infect Disord Drug Targets 2009 1.01
41 Preferential self-association of basic fibroblast growth factor is stabilized by heparin during receptor dimerization and activation. Proc Natl Acad Sci U S A 1996 0.99
42 Calorimetric examination of high-affinity Src SH2 domain-tyrosyl phosphopeptide binding: dissection of the phosphopeptide sequence specificity and coupling energetics. Biochemistry 1999 0.97
43 Mass spectrometric and thermodynamic studies reveal the role of water molecules in complexes formed between SH2 domains and tyrosyl phosphopeptides. Structure 1998 0.95
44 Supraomohyoid neck dissection in the treatment of head and neck tumors. Survival results in 212 cases. Arch Otolaryngol Head Neck Surg 1993 0.94
45 Common amino acid domain among endopolygalacturonases of ascomycete fungi. Appl Environ Microbiol 1990 0.93
46 Analgesic effects of kelatorphan, a new highly potent inhibitor of multiple enkephalin degrading enzymes. Eur J Pharmacol 1984 0.91
47 New insights into heparin-induced FGF oligomerization. Nat Struct Biol 1998 0.89
48 Mutational investigation of the specificity determining region of the Src SH2 domain. J Mol Biol 2000 0.88
49 Binding of the bidentate inhibitor [3H]HACBO-Gly to the rat brain neutral endopeptidase "enkephalinase". Biochem Biophys Res Commun 1985 0.88
50 Role of electrostatic interactions in SH2 domain recognition: salt-dependence of tyrosyl-phosphorylated peptide binding to the tandem SH2 domain of the Syk kinase and the single SH2 domain of the Src kinase. Biochemistry 2000 0.87
51 Synthesis of fluorescent acyl-cholines with agonistic properties: pharmacological activity on Electrophorus electroplaque and interaction in vitro with Torpedo receptor-rich membrane fragments. FEBS Lett 1976 0.87
52 Pre-steady-state kinetic studies of Saccharomyces cerevisiae myristoylCoA:protein N-myristoyltransferase mutants identify residues involved in catalysis. Biochemistry 2001 0.87
53 Differences in the structural requirements for selective interaction with neutral metalloendopeptidase (enkephalinase) or angiotensin-converting enzyme. Molecular investigation by use of new thiol inhibitors. Eur J Biochem 1984 0.85
54 Recombinant neutral endopeptidase-24.11 expressed in mouse neuroblastoma cells is associated with neurite membranes. Biochem J 1990 0.85
55 D2 dopamine receptor gene and alcoholism. J Psychiatr Res 1993 0.85
56 In vitro and in vivo effects of kelatorphan on enkephalin metabolism in rodent brain. Eur J Pharmacol 1985 0.85
57 SH2 domains: from structure to energetics, a dual approach to the study of structure-function relationships. Med Res Rev 1999 0.84
58 Selective labelling by [3H]trimethisoquin azide of polypeptide chains present in acetylcholine receptor-rich membranes from Torpedo marmorata. FEBS Lett 1980 0.83
59 Drosophila rab GDI mutants disrupt development but have normal Rab membrane extraction. Genesis 2001 0.83
60 Differential recognition of "enkephalinase" and angiotensin-converting enzyme by new carboxyalkyl inhibitors. Life Sci 1982 0.82
61 Synthesis and pharmacological activity on Electrophorus electricus electroplaque of photoaffinity labelling derivatives of the non-competitive blockers di- and tri-methisoquin. FEBS Lett 1980 0.81
62 Human tyrosine hydroxylase isoforms. Inhibition by excess tetrahydropterin and unusual behavior of isoform 3 after camp-dependent protein kinase phosphorylation. J Biol Chem 1998 0.81
63 Bidentate peptides: highly potent new inhibitors of enkephalin degrading enzymes. Life Sci 1984 0.80
64 Neuronal localization of the neutral endopeptidase 'enkephalinase' in rat brain revealed by lesions and autoradiography. EMBO J 1986 0.80
65 Connexin 30, a new marker of hyperproliferative epidermis. Br J Dermatol 2006 0.80
66 [Regional distribution of enkephalinase in the rat brain by autoradiography]. C R Acad Sci III 1984 0.80
67 The lon gene and photoprotection in Escherichia coli K-12. Photochem Photobiol 1984 0.79
68 New bidentates as full inhibitors of enkephalin-degrading enzymes: synthesis and analgesic properties. J Med Chem 1985 0.79
69 Pseudoautosomal region in schizophrenia: linkage analysis of seven loci by sib-pair and lod-score methods. Psychiatry Res 1994 0.77
70 Regulation of antigen receptor function by protein tyrosine kinases. Prog Biophys Mol Biol 1999 0.77
71 Kelatorphan: a full inhibitor of enkephalin degrading enzymes. Biochemical and pharmacological properties, regional distribution of enkephalinase in rat brain by use of a tritiated derivative. Neuropeptides 1985 0.77
72 Structural analysis by circular dichroism of some enzymes involved in plant cell wall degradation. FEBS Lett 1991 0.77
73 New enkephalinase inhibitors as probes to differentiate "enkephalinase" and angiotensin-converting-enzyme active sites. Life Sci 1983 0.76
74 pH-Dependent self-association of the Src homology 2 (SH2) domain of the Src homologous and collagen-like (SHC) protein. Protein Sci 1996 0.75
75 A 1.5-Mb physical map of the hidrotic ectodermal dysplasia (Clouston syndrome) gene region on human chromosome 13q11. Genomics 2000 0.75
76 Naloxone-induced withdrawal syndrome after administration of selective opioid agonists or after activation of the endogenous enkephalinergic system. Prog Clin Biol Res 1990 0.75
77 [Surgical treatment of acute pancreatitis: experience at a general hospital]. Rev Paul Med 1990 0.75
78 Structural requirements for agonist and noncompetitive blocking action of acylcholine derivatives on Electrophorus electricus electroplaque. Mol Pharmacol 1980 0.75
79 Refined localization of the gene for Clouston syndrome (hidrotic ectodermal dysplasia) in a large French family. Br J Dermatol 2000 0.75
80 [Contribution of satellite image processing to the cartography of sahelian pastures]. Rev Elev Med Vet Pays Trop 1977 0.75
81 Targeting of neutral endopeptidase 24.11 in polarized cells. Biochem Soc Trans 1993 0.75