Published in Handb Exp Pharmacol on January 01, 2009
Combination of secretin and fluvastatin ameliorates the polyuria associated with X-linked nephrogenic diabetes insipidus in mice. Kidney Int (2014) 2.08
Physiology and pathophysiology of the calcium-sensing receptor in the kidney. Am J Physiol Renal Physiol (2009) 2.02
Treating lysosomal storage diseases with pharmacological chaperones: from concept to clinics. EMBO Mol Med (2009) 1.49
Small-molecule screening identifies modulators of aquaporin-2 trafficking. J Am Soc Nephrol (2013) 1.41
Cancer biomarker discovery: the entropic hallmark. PLoS One (2010) 1.26
The Aquaporin gene family of the yellow fever mosquito, Aedes aegypti. PLoS One (2010) 1.20
Potassium channel silencing by constitutive endocytosis and intracellular sequestration. J Biol Chem (2009) 1.17
Reciprocal regulation of aquaporin-2 abundance and degradation by protein kinase A and p38-MAP kinase. J Am Soc Nephrol (2010) 1.16
Simvastatin enhances aquaporin-2 surface expression and urinary concentration in vasopressin-deficient Brattleboro rats through modulation of Rho GTPase. Am J Physiol Renal Physiol (2011) 1.08
A-kinase anchoring proteins as potential drug targets. Br J Pharmacol (2012) 1.07
Calcitonin has a vasopressin-like effect on aquaporin-2 trafficking and urinary concentration. J Am Soc Nephrol (2010) 1.05
Collecting duct principal cell transport processes and their regulation. Clin J Am Soc Nephrol (2014) 1.02
Voltage-regulated water flux through aquaporin channels in silico. Biophys J (2010) 1.01
Rapid aquaporin translocation regulates cellular water flow: mechanism of hypotonicity-induced subcellular localization of aquaporin 1 water channel. J Biol Chem (2012) 0.97
Cell biology of vasopressin-regulated aquaporin-2 trafficking. Pflugers Arch (2012) 0.97
New insights into the dynamic regulation of water and acid-base balance by renal epithelial cells. Am J Physiol Cell Physiol (2012) 0.92
Calcium-sensing receptor and aquaporin 2 interplay in hypercalciuria-associated renal concentrating defect in humans. An in vivo and in vitro study. PLoS One (2012) 0.90
Fluvastatin modulates renal water reabsorption in vivo through increased AQP2 availability at the apical plasma membrane of collecting duct cells. Pflugers Arch (2011) 0.88
Mechanism for targeting the A-kinase anchoring protein AKAP18δ to the membrane. J Biol Chem (2012) 0.87
NADPH oxidase 4 deficiency reduces aquaporin-2 mRNA expression in cultured renal collecting duct principal cells via increased PDE3 and PDE4 activity. PLoS One (2014) 0.85
Aquaporin-2: new mutations responsible for autosomal-recessive nephrogenic diabetes insipidus-update and epidemiology. Clin Kidney J (2012) 0.84
Mechanisms of vasopressin-induced intracellular Ca2+ oscillations in rat inner medullary collecting duct. Am J Physiol Renal Physiol (2010) 0.84
Functional polymorphisms affecting the clinically important arginine-137 residue of AVPR2 do not influence serum sodium concentration at the population level. Physiol Genomics (2013) 0.83
PACAP suppresses dry eye signs by stimulating tear secretion. Nat Commun (2016) 0.83
Cell culture models and animal models for studying the patho-physiological role of renal aquaporins. Cell Mol Life Sci (2011) 0.82
EGF Receptor Inhibition by Erlotinib Increases Aquaporin 2-Mediated Renal Water Reabsorption. J Am Soc Nephrol (2016) 0.81
Function of cGMP-dependent protein kinase II in volume load-induced diuresis. Pflugers Arch (2014) 0.81
Hydrogen sulfide targets EGFR Cys797/Cys798 residues to induce Na(+)/K(+)-ATPase endocytosis and inhibition in renal tubular epithelial cells and increase sodium excretion in chronic salt-loaded rats. Antioxid Redox Signal (2014) 0.80
Intestinal fluid absorption in anadromous salmonids: importance of tight junctions and aquaporins. Front Physiol (2012) 0.80
Water homeostasis in the fish oocyte: new insights into the role and molecular regulation of a teleost-specific aquaporin. Fish Physiol Biochem (2012) 0.79
Diabetes insipidus: a challenging diagnosis with new drug therapies. ISRN Nephrol (2013) 0.79
The Caenorhabditis elegans Excretory System: A Model for Tubulogenesis, Cell Fate Specification, and Plasticity. Genetics (2016) 0.79
Effect of mutations in putative hormone binding sites on V2 vasopressin receptor function. Res Pharm Sci (2015) 0.78
The Trafficking of the Water Channel Aquaporin-2 in Renal Principal Cells-a Potential Target for Pharmacological Intervention in Cardiovascular Diseases. Front Pharmacol (2016) 0.78
Mechanisms of cell polarity and aquaporin sorting in the nephron. Pflugers Arch (2011) 0.78
Human Organic Solute Transporter (hOST): protein interaction and membrane sorting process. Int J Biochem Mol Biol (2012) 0.77
Molecular cloning, overexpression and characterization of a novel water channel protein from Rhodobacter sphaeroides. PLoS One (2014) 0.77
The role of v2 receptor antagonists in the treatment of hyponatremia. Electrolyte Blood Press (2013) 0.77
PKCα regulates vasopressin-induced aquaporin-2 trafficking in mouse kidney collecting duct cells in vitro via altering microtubule assembly. Acta Pharmacol Sin (2012) 0.76
A decrease in aquaporin 2 excretion is associated with bed rest induced high calciuria. J Transl Med (2014) 0.76
Molecular mechanisms regulating aquaporin-2 in kidney collecting duct. Am J Physiol Renal Physiol (2016) 0.75
Homocysteine induces hypophosphorylation of intermediate filaments and reorganization of actin cytoskeleton in C6 glioma cells. Cell Mol Neurobiol (2009) 0.75
AKAP complex regulates Ca2+ re-uptake into heart sarcoplasmic reticulum. EMBO Rep (2007) 1.72
Isoform-selective susceptibility of DISC1/phosphodiesterase-4 complexes to dissociation by elevated intracellular cAMP levels. J Neurosci (2007) 1.64
A Role of myosin Vb and Rab11-FIP2 in the aquaporin-2 shuttle. Traffic (2006) 1.62
Mechanisms of protein kinase A anchoring. Int Rev Cell Mol Biol (2010) 1.52
Compartmentalization of cAMP-dependent signaling by phosphodiesterase-4D is involved in the regulation of vasopressin-mediated water reabsorption in renal principal cells. J Am Soc Nephrol (2006) 1.50
Minireview: aquaporin 2 trafficking. Endocrinology (2005) 1.49
Scanning peptide array analyses identify overlapping binding sites for the signalling scaffold proteins, beta-arrestin and RACK1, in cAMP-specific phosphodiesterase PDE4D5. Biochem J (2006) 1.46
Small-molecule screening identifies modulators of aquaporin-2 trafficking. J Am Soc Nephrol (2013) 1.41
Identification of a novel A-kinase anchoring protein 18 isoform and evidence for its role in the vasopressin-induced aquaporin-2 shuttle in renal principal cells. J Biol Chem (2004) 1.39
Pharmacochaperones post-translationally enhance cell surface expression by increasing conformational stability of wild-type and mutant vasopressin V2 receptors. J Biol Chem (2004) 1.33
p75 neurotrophin receptor regulates tissue fibrosis through inhibition of plasminogen activation via a PDE4/cAMP/PKA pathway. J Cell Biol (2007) 1.30
Ligand-dependent differences in the internalization of endothelin A and endothelin B receptor heterodimers. J Biol Chem (2004) 1.26
Heteroligomerization of an Aquaporin-2 mutant with wild-type Aquaporin-2 and their misrouting to late endosomes/lysosomes explains dominant nephrogenic diabetes insipidus. Hum Mol Genet (2002) 1.18
cAMP-induced AQP2 translocation is associated with RhoA inhibition through RhoA phosphorylation and interaction with RhoGDI. J Cell Sci (2003) 1.18
Small molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes. J Biol Chem (2010) 1.18
Reciprocal regulation of aquaporin-2 abundance and degradation by protein kinase A and p38-MAP kinase. J Am Soc Nephrol (2010) 1.16
Containment of an outbreak of KPC-3-producing Klebsiella pneumoniae in Italy. J Clin Microbiol (2011) 1.12
The corticotropin-releasing factor receptor type 2a contains an N-terminal pseudo signal peptide. J Biol Chem (2006) 1.11
Direct binding between Orai1 and AC8 mediates dynamic interplay between Ca2+ and cAMP signaling. Sci Signal (2012) 1.10
Mapping binding sites for the PDE4D5 cAMP-specific phosphodiesterase to the N- and C-domains of beta-arrestin using spot-immobilized peptide arrays. Biochem J (2007) 1.10
Compartmentalized cAMP signalling in regulated exocytic processes in non-neuronal cells. Cell Signal (2007) 1.10
Actin remodeling requires ERM function to facilitate AQP2 apical targeting. J Cell Sci (2005) 1.10
Cyclic AMP is sufficient for triggering the exocytic recruitment of aquaporin-2 in renal epithelial cells. EMBO Rep (2003) 1.09
Hypotonicity induces aquaporin-2 internalization and cytosol-to-membrane translocation of ICln in renal cells. Endocrinology (2006) 1.07
A-kinase anchoring proteins as potential drug targets. Br J Pharmacol (2012) 1.07
Extracellular calcium antagonizes forskolin-induced aquaporin 2 trafficking in collecting duct cells. Kidney Int (2004) 1.06
Disease-causing V(2) vasopressin receptors are retained in different compartments of the early secretory pathway. Traffic (2004) 1.06
Cell-biologic and functional analyses of five new Aquaporin-2 missense mutations that cause recessive nephrogenic diabetes insipidus. J Am Soc Nephrol (2002) 1.06
High-affinity AKAP7delta-protein kinase A interaction yields novel protein kinase A-anchoring disruptor peptides. Biochem J (2006) 1.04
The signal peptide of the G protein-coupled human endothelin B receptor is necessary for translocation of the N-terminal tail across the endoplasmic reticulum membrane. J Biol Chem (2002) 1.04
Renal expression of sodium transporters and aquaporin-2 in hypothyroid rats. Am J Physiol Renal Physiol (2003) 1.04
Microtubules are needed for the perinuclear positioning of aquaporin-2 after its endocytic retrieval in renal principal cells. Am J Physiol Cell Physiol (2007) 1.02
Characterization of two novel missense mutations in the AQP2 gene causing nephrogenic diabetes insipidus. Nephron Physiol (2006) 1.02
MEK1 binds directly to betaarrestin1, influencing both its phosphorylation by ERK and the timing of its isoprenaline-stimulated internalization. J Biol Chem (2009) 1.02
The signal peptide of the rat corticotropin-releasing factor receptor 1 promotes receptor expression but is not essential for establishing a functional receptor. Biochem J (2005) 1.02
The extracellular N terminus of the endothelin B (ETB) receptor is cleaved by a metalloprotease in an agonist-dependent process. J Biol Chem (2002) 1.01
Disuse of rat muscle in vivo reduces protein kinase C activity controlling the sarcolemma chloride conductance. J Physiol (2007) 1.01
The prostaglandin E2 analogue sulprostone antagonizes vasopressin-induced antidiuresis through activation of Rho. J Cell Sci (2003) 1.01
Fluorescence resonance energy transfer analysis reveals the existence of endothelin-A and endothelin-B receptor homodimers. J Cardiovasc Pharmacol (2004) 0.97
PKD1 haploinsufficiency causes a syndrome of inappropriate antidiuresis in mice. J Am Soc Nephrol (2007) 0.97
Functional involvement of VAMP/synaptobrevin-2 in cAMP-stimulated aquaporin 2 translocation in renal collecting duct cells. J Cell Sci (2002) 0.97
Glycogen synthase kinase 3beta interaction protein functions as an A-kinase anchoring protein. J Biol Chem (2009) 0.96
Integrin signaling modulates AQP2 trafficking via Arg-Gly-Asp (RGD) motif. Cell Physiol Biochem (2011) 0.96
Spatial organisation of AKAP18 and PDE4 isoforms in renal collecting duct principal cells. Eur J Cell Biol (2006) 0.96
Ser-256 phosphorylation dynamics of Aquaporin 2 during maturation from the ER to the vesicular compartment in renal cells. FASEB J (2003) 0.95
AQP2 exocytosis in the renal collecting duct -- involvement of SNARE isoforms and the regulatory role of Munc18b. J Cell Sci (2008) 0.94
Polarized traffic towards the cell surface: how to find the route. Biol Cell (2009) 0.93
The hydrophobic amino acid residues in the membrane-proximal C tail of the G protein-coupled vasopressin V2 receptor are necessary for transport-competent receptor folding. FEBS Lett (2005) 0.93
Aquaporin-1, nothing but a water channel. J Biol Chem (2003) 0.92
Selective SUMO modification of cAMP-specific phosphodiesterase-4D5 (PDE4D5) regulates the functional consequences of phosphorylation by PKA and ERK. Biochem J (2010) 0.91
Functional involvement of Annexin-2 in cAMP induced AQP2 trafficking. Pflugers Arch (2008) 0.90
Calcium-sensing receptor and aquaporin 2 interplay in hypercalciuria-associated renal concentrating defect in humans. An in vivo and in vitro study. PLoS One (2012) 0.90
MAL/VIP17, a new player in the regulation of NKCC2 in the kidney. Mol Biol Cell (2010) 0.90
Elucidation of a structural basis for the inhibitor-driven, p62 (SQSTM1)-dependent intracellular redistribution of cAMP phosphodiesterase-4A4 (PDE4A4). J Med Chem (2011) 0.90
Role of the p66Shc isoform in insulin-like growth factor I receptor signaling through MEK/Erk and regulation of actin cytoskeleton in rat myoblasts. J Biol Chem (2004) 0.89
Highly functionalized terpyridines as competitive inhibitors of AKAP-PKA interactions. Angew Chem Int Ed Engl (2013) 0.88
Fluvastatin modulates renal water reabsorption in vivo through increased AQP2 availability at the apical plasma membrane of collecting duct cells. Pflugers Arch (2011) 0.88
AQP5 is expressed in type-B intercalated cells in the collecting duct system of the rat, mouse and human kidney. Cell Physiol Biochem (2011) 0.87
Mechanism for targeting the A-kinase anchoring protein AKAP18δ to the membrane. J Biol Chem (2012) 0.87
Selective decrease in urinary aquaporin 2 and increase in prostaglandin E2 excretion is associated with postobstructive polyuria in human congenital hydronephrosis. J Am Soc Nephrol (2004) 0.87
The sequence after the signal peptide of the G protein-coupled endothelin B receptor is required for efficient translocon gating at the endoplasmic reticulum membrane. Mol Pharmacol (2009) 0.86
Arrestin-independent internalization and recycling of the urotensin receptor contribute to long-lasting urotensin II-mediated vasoconstriction. Circ Res (2005) 0.86
Structural determinants for selective recognition of peptide ligands for endothelin receptor subtypes ETA and ETB. J Pept Sci (2009) 0.86
Functional significance of cleavable signal peptides of G protein-coupled receptors. Eur J Cell Biol (2011) 0.85
Variant amino acids in the extracellular loops of murine and human vasopressin V2 receptors account for differences in cell surface expression and ligand affinity. Mol Endocrinol (2002) 0.85
Counteracting vasopressin-mediated water reabsorption by ATP, dopamine, and phorbol esters: mechanisms of action. Am J Physiol Renal Physiol (2011) 0.84