Published in Fly (Austin) on November 09, 2008
Collapse of germline piRNAs in the absence of Argonaute3 reveals somatic piRNAs in flies. Cell (2009) 4.39
High-throughput genome editing and phenotyping facilitated by high resolution melting curve analysis. PLoS One (2014) 1.60
Thermosensory and nonthermosensory isoforms of Drosophila melanogaster TRPA1 reveal heat-sensor domains of a thermoTRP Channel. Cell Rep (2012) 1.56
Drosophila Mtm and class II PI3K coregulate a PI(3)P pool with cortical and endolysosomal functions. J Cell Biol (2010) 1.09
De novo ORFs in Drosophila are important to organismal fitness and evolved rapidly from previously non-coding sequences. PLoS Genet (2013) 1.06
Three structure-selective endonucleases are essential in the absence of BLM helicase in Drosophila. PLoS Genet (2011) 1.03
Targeting the motor regulator Klar to lipid droplets. BMC Cell Biol (2011) 0.97
Reverse genetics in eukaryotes. Biol Cell (2010) 0.97
Mutations in the catalytic loop HRD motif alter the activity and function of Drosophila Src64. PLoS One (2011) 0.87
Rootletin organizes the ciliary rootlet to achieve neuron sensory function in Drosophila. J Cell Biol (2015) 0.84
Drosophila FANCM helicase prevents spontaneous mitotic crossovers generated by the MUS81 and SLX1 nucleases. Genetics (2014) 0.82
EMS mutagenesis in mature seed-derived rice calli as a new method for rapidly obtaining TILLING mutant populations. Plant Methods (2014) 0.82
Control of Neural Daughter Cell Proliferation by Multi-level Notch/Su(H)/E(spl)-HLH Signaling. PLoS Genet (2016) 0.79
Mcm10 is required for oogenesis and early embryogenesis in Drosophila. Mech Dev (2015) 0.76
Tudor-SN Interacts with Piwi Antagonistically in Regulating Spermatogenesis but Synergistically in Silencing Transposons in Drosophila. PLoS Genet (2016) 0.76
Temporal control of bidirectional lipid-droplet motion in Drosophila depends on the ratio of kinesin-1 and its co-factor Halo. J Cell Sci (2016) 0.75
SIFT: Predicting amino acid changes that affect protein function. Nucleic Acids Res (2003) 52.26
Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm. Nat Protoc (2009) 38.62
Accounting for human polymorphisms predicted to affect protein function. Genome Res (2002) 14.10
Identification of functional elements and regulatory circuits by Drosophila modENCODE. Science (2010) 12.39
Genome-wide analysis of Arabidopsis thaliana DNA methylation uncovers an interdependence between methylation and transcription. Nat Genet (2006) 11.88
Unlocking the secrets of the genome. Nature (2009) 11.80
Predicting the effects of amino acid substitutions on protein function. Annu Rev Genomics Hum Genet (2006) 9.80
The histone variant H3.3 marks active chromatin by replication-independent nucleosome assembly. Mol Cell (2002) 9.80
Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project. Science (2010) 9.78
The epigenetic progenitor origin of human cancer. Nat Rev Genet (2006) 9.65
Genome-scale profiling of histone H3.3 replacement patterns. Nat Genet (2005) 7.22
Histone H3.3 is enriched in covalent modifications associated with active chromatin. Proc Natl Acad Sci U S A (2004) 4.88
Genome-wide kinetics of nucleosome turnover determined by metabolic labeling of histones. Science (2010) 4.72
Centromeric nucleosomes induce positive DNA supercoils. Cell (2009) 4.57
DNA demethylation in the Arabidopsis genome. Proc Natl Acad Sci U S A (2007) 4.55
SIFT web server: predicting effects of amino acid substitutions on proteins. Nucleic Acids Res (2012) 4.45
Histone variants--ancient wrap artists of the epigenome. Nat Rev Mol Cell Biol (2010) 4.45
Large-scale discovery of induced point mutations with high-throughput TILLING. Genome Res (2003) 4.39
Histone H2A.Z and DNA methylation are mutually antagonistic chromatin marks. Nature (2008) 4.20
Histone replacement marks the boundaries of cis-regulatory domains. Science (2007) 4.06
Spectrum of chemically induced mutations from a large-scale reverse-genetic screen in Arabidopsis. Genetics (2003) 3.70
Sequencing of a rice centromere uncovers active genes. Nat Genet (2004) 3.66
CODEHOP (COnsensus-DEgenerate Hybrid Oligonucleotide Primer) PCR primer design. Nucleic Acids Res (2003) 3.55
DNA methylation profiling identifies CG methylation clusters in Arabidopsis genes. Curr Biol (2005) 3.54
Phylogenomics of the nucleosome. Nat Struct Biol (2003) 3.52
DNA demethylation by DNA repair. Trends Genet (2009) 3.49
Genome-wide profiling of DNA methylation reveals transposon targets of CHROMOMETHYLASE3. Curr Biol (2002) 3.37
Extensive demethylation of repetitive elements during seed development underlies gene imprinting. Science (2009) 3.33
A comprehensive map of insulator elements for the Drosophila genome. PLoS Genet (2010) 3.25
Tetrameric structure of centromeric nucleosomes in interphase Drosophila cells. PLoS Biol (2007) 3.25
Histone H3 variants specify modes of chromatin assembly. Proc Natl Acad Sci U S A (2002) 3.06
Centromeric localization and adaptive evolution of an Arabidopsis histone H3 variant. Plant Cell (2002) 2.72
Regulation of nucleosome dynamics by histone modifications. Nat Struct Mol Biol (2013) 2.71
Spreading of silent chromatin: inaction at a distance. Nat Rev Genet (2006) 2.64
Discovery of induced point mutations in maize genes by TILLING. BMC Plant Biol (2004) 2.57
Major evolutionary transitions in centromere complexity. Cell (2009) 2.49
Discovery of chemically induced mutations in rice by TILLING. BMC Plant Biol (2007) 2.46
Efficient discovery of DNA polymorphisms in natural populations by Ecotilling. Plant J (2004) 2.45
TILLING. Traditional mutagenesis meets functional genomics. Plant Physiol (2004) 2.29
A simple method for gene expression and chromatin profiling of individual cell types within a tissue. Dev Cell (2010) 2.24
Epigenome characterization at single base-pair resolution. Proc Natl Acad Sci U S A (2011) 2.22
Conflict begets complexity: the evolution of centromeres. Curr Opin Genet Dev (2002) 2.14
Mismatch cleavage by single-strand specific nucleases. Nucleic Acids Res (2004) 2.14
TILLING to detect induced mutations in soybean. BMC Plant Biol (2008) 2.13
Genome-wide analysis of DNA methylation patterns. Development (2007) 2.13
A protocol for TILLING and Ecotilling in plants and animals. Nat Protoc (2006) 2.09
Chromatin immunoprecipitation reveals that the 180-bp satellite repeat is the key functional DNA element of Arabidopsis thaliana centromeres. Genetics (2003) 2.05
Maize centromeres: organization and functional adaptation in the genetic background of oat. Plant Cell (2004) 2.01
Chaperone-mediated assembly of centromeric chromatin in vitro. Proc Natl Acad Sci U S A (2006) 1.98
Distinct HP1 and Su(var)3-9 complexes bind to sets of developmentally coexpressed genes depending on chromosomal location. Genes Dev (2003) 1.96
TILLING: practical single-nucleotide mutation discovery. Plant J (2006) 1.94
Adaptive evolution of centromere proteins in plants and animals. J Biol (2004) 1.90
The INTACT method for cell type-specific gene expression and chromatin profiling in Arabidopsis thaliana. Nat Protoc (2010) 1.87
A unified phylogeny-based nomenclature for histone variants. Epigenetics Chromatin (2012) 1.82
Structure, dynamics, and evolution of centromeric nucleosomes. Proc Natl Acad Sci U S A (2007) 1.81
Maintenance of chromatin states: an open-and-shut case. Curr Opin Cell Biol (2003) 1.72
High-throughput TILLING for functional genomics. Methods Mol Biol (2003) 1.70
Changes in H2A.Z occupancy and DNA methylation during B-cell lymphomagenesis. Genome Res (2010) 1.69
Centromere targeting element within the histone fold domain of Cid. Mol Cell Biol (2002) 1.64
Epigenetic consequences of nucleosome dynamics. Cell (2002) 1.60
Doxorubicin enhances nucleosome turnover around promoters. Curr Biol (2013) 1.58
Positive selection drives the evolution of rhino, a member of the heterochromatin protein 1 family in Drosophila. PLoS Genet (2005) 1.57
Chromatin and siRNA pathways cooperate to maintain DNA methylation of small transposable elements in Arabidopsis. Genome Biol (2005) 1.55
Automated band mapping in electrophoretic gel images using background information. Nucleic Acids Res (2005) 1.49
Recurrent evolution of DNA-binding motifs in the Drosophila centromeric histone. Proc Natl Acad Sci U S A (2002) 1.48
Tripartite organization of centromeric chromatin in budding yeast. Proc Natl Acad Sci U S A (2011) 1.47
Genomic analysis of parent-of-origin allelic expression in Arabidopsis thaliana seeds. PLoS One (2011) 1.45
Germline histone dynamics and epigenetics. Curr Opin Cell Biol (2007) 1.42
Histone H3.3 variant dynamics in the germline of Caenorhabditis elegans. PLoS Genet (2006) 1.42
H2A.Z nucleosomes enriched over active genes are homotypic. Nat Struct Mol Biol (2010) 1.41
DNA methylation dynamics in plant genomes. Biochim Biophys Acta (2007) 1.41
Transcription and histone modifications in the recombination-free region spanning a rice centromere. Plant Cell (2005) 1.37
Adaptive evolution of the histone fold domain in centromeric histones. Mol Biol Evol (2004) 1.35
Cell-type-specific nuclei purification from whole animals for genome-wide expression and chromatin profiling. Genome Res (2012) 1.32
A native chromatin purification system for epigenomic profiling in Caenorhabditis elegans. Nucleic Acids Res (2009) 1.30
High-throughput discovery of rare human nucleotide polymorphisms by Ecotilling. Nucleic Acids Res (2006) 1.28
Centromeres put epigenetics in the driver's seat. Trends Biochem Sci (2006) 1.28
Heat shock reduces stalled RNA polymerase II and nucleosome turnover genome-wide. Genes Dev (2011) 1.26
ISWI and CHD chromatin remodelers bind promoters but act in gene bodies. PLoS Genet (2013) 1.25
Histone variants: dynamic punctuation in transcription. Genes Dev (2014) 1.22
Centromeres convert but don't cross. PLoS Biol (2010) 1.22
Histone variants in pluripotency and disease. Development (2013) 1.21
Epigenomic profiling using microarrays. Biotechniques (2003) 1.21
Silencing of transposons in plant genomes: kick them when they're down. Genome Biol (2004) 1.15
Retention of induced mutations in a Drosophila reverse-genetic resource. Genetics (2008) 1.14
The nucleosomal barrier to promoter escape by RNA polymerase II is overcome by the chromatin remodeler Chd1. Elife (2014) 1.13
Intergenic locations of rice centromeric chromatin. PLoS Biol (2008) 1.13
Phylogeny as the basis for naming histones. Trends Genet (2013) 1.12
The CentO satellite confers translational and rotational phasing on cenH3 nucleosomes in rice centromeres. Proc Natl Acad Sci U S A (2013) 1.11
Tech.Sight. Phage display. Affinity selection from biological libraries. Science (2002) 1.11
Positive selection of Iris, a retroviral envelope-derived host gene in Drosophila melanogaster. PLoS Genet (2005) 1.09
Transcribing through the nucleosome. Trends Biochem Sci (2014) 1.07
Quantitative epigenetics. Nat Genet (2003) 1.07
Labile H3.3+H2A.Z nucleosomes mark 'nucleosome-free regions'. Nat Genet (2009) 1.05
Epigenetic inheritance in Arabidopsis: selective silence. Curr Opin Genet Dev (2005) 1.03
Mot1 redistributes TBP from TATA-containing to TATA-less promoters. Mol Cell Biol (2013) 1.02