PubRank

F Eckstein

Author PubWeight™ 404.83‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The rapid generation of oligonucleotide-directed mutations at high frequency using phosphorothioate-modified DNA. Nucleic Acids Res 1985 12.11
2 Nucleoside phosphorothioates. Annu Rev Biochem 1985 7.55
3 Incorporation of phosphorothioate groups into fd and phi X174 DNA. Biochemistry 1977 6.10
4 Inhibition of restriction endonuclease Nci I cleavage by phosphorothioate groups and its application to oligonucleotide-directed mutagenesis. Nucleic Acids Res 1986 5.90
5 Deoxynucleoside [1-thio]triphosphates prevent proofreading during in vitro DNA synthesis. Proc Natl Acad Sci U S A 1981 4.14
6 The use of phosphorothioate-modified DNA in restriction enzyme reactions to prepare nicked DNA. Nucleic Acids Res 1985 3.65
7 5'-3' exonucleases in phosphorothioate-based oligonucleotide-directed mutagenesis. Nucleic Acids Res 1988 3.41
8 Kinetic characterization of ribonuclease-resistant 2'-modified hammerhead ribozymes. Science 1991 3.18
9 Guanosine 5'-O-(2-thiodiphosphate). An inhibitor of adenylate cyclase stimulation by guanine nucleotides and fluoride ions. J Biol Chem 1979 3.12
10 Synthesis and characterization of an octanucleotide containing the EcoRI recognition sequence with a phosphorothioate group at the cleavage site. Biochemistry 1984 3.03
11 DNA and RNA sequence determination based on phosphorothioate chemistry. Science 1988 2.95
12 Numbering system for the hammerhead. Nucleic Acids Res 1992 2.74
13 The magnesium ion-dependent adenosine triphosphatase of myosin. Two-step processes of adenosine triphosphate association and adenosine diphosphate dissociation. Biochem J 1974 2.57
14 A study of the mechanism of DNA polymerase I from Escherichia coli with diastereomeric phosphorothioate analogs of deoxyadenosine triphosphate. J Biol Chem 1979 2.37
15 Direct sequencing of polymerase chain reaction amplified DNA fragments through the incorporation of deoxynucleoside alpha-thiotriphosphates. Nucleic Acids Res 1988 2.28
16 Incomplete primer extension during in vitro DNA amplification catalyzed by Taq polymerase; exploitation for DNA sequencing. Nucleic Acids Res 1989 2.21
17 Synthesis and configurational analysis of a dinucleoside phosphate isotopically chiral at phosphorus. Stereochemical course of Penicillium citrum nuclease P1 reaction. Biochemistry 1983 2.18
18 Properties of overexpressed phage T5 D15 exonuclease. Similarities with Escherichia coli DNA polymerase I 5'-3' exonuclease. J Biol Chem 1990 2.17
19 Estimation of distal radius failure load with micro-finite element analysis models based on three-dimensional peripheral quantitative computed tomography images. Bone 2002 2.14
20 Interaction of hydrolysis-resistant analogs of cyclic GMP with the phosphodiesterase and light-sensitive channel of retinal rod outer segments. Proc Natl Acad Sci U S A 1985 2.04
21 Synthesis and properties of diastereoisomers of adenosine 5'-(O-1-thiotriphosphate) and adenosine 5'-(O-2-thiotriphosphate). Biochemistry 1976 2.02
22 Incorporation of terminal phosphorothioates into oligonucleotides. Nucleic Acids Res 1998 2.00
23 The structure, function and application of the hammerhead ribozyme. Eur J Biochem 1997 1.94
24 Left-handed DNA: from synthetic polymers to chromosomes. J Biomol Struct Dyn 1983 1.90
25 [Synthesis of oligodesoxynucleotides with phosphoric acid triester]. Chem Ber 1969 1.89
26 Protection of oligonucleotide primers against degradation by DNA polymerase I. Biochemistry 1987 1.87
27 Modified oligonucleotides: synthesis and strategy for users. Annu Rev Biochem 1998 1.85
28 Absolute configuration of the diastereomers of adenosine 5'-O-(1-thiotriphosphate): consequences for the stereochemistry of polymerization by DNA-dependent RNA polymerase from Escherichia coli. Proc Natl Acad Sci U S A 1978 1.82
29 Absolute stereochemistry of the second step of ribonuclease action. Nature 1970 1.80
30 Two autolytic processing reactions of a satellite RNA proceed with inversion of configuration. Nucleic Acids Res 1990 1.80
31 Fluorescent labelling of tRNA and oligodeoxynucleotides using T4 RNA ligase. Nucleic Acids Res 1984 1.77
32 Regional analysis of femorotibial cartilage loss in a subsample from the Osteoarthritis Initiative progression subcohort. Osteoarthritis Cartilage 2008 1.76
33 Magnetic resonance imaging-based assessment of cartilage loss in severe osteoarthritis: accuracy, precision, and diagnostic value. Arthritis Rheum 2001 1.76
34 Quantitative determination of joint incongruity and pressure distribution during simulated gait and cartilage thickness in the human hip joint. J Orthop Res 1999 1.75
35 Nucleoside phosphorothioates. J Am Chem Soc 1970 1.71
36 A three-dimensional model for the hammerhead ribozyme based on fluorescence measurements. Science 1994 1.71
37 Geometry of the first step in the action of ribonuclease-A (in-line geometry-uridine2',3'-cyclic thiophosphate- 31 P NMR). Proc Natl Acad Sci U S A 1972 1.71
38 Interaction of Escherichia coli tRNA(Ser) with its cognate aminoacyl-tRNA synthetase as determined by footprinting with phosphorothioate-containing tRNA transcripts. Proc Natl Acad Sci U S A 1991 1.69
39 Hammerhead ribozymes: importance of stem-loop II for activity. Proc Natl Acad Sci U S A 1993 1.69
40 MRI protocols for whole-organ assessment of the knee in osteoarthritis. Osteoarthritis Cartilage 2006 1.68
41 Stereochemistry of polymerization by DNA-dependent RNA-polymerase from Escherichia coli: an investigation with a diastereomeric ATP-analogue. Proc Natl Acad Sci U S A 1976 1.65
42 Diastereomers of 5'-O-adenosyl 3'-O-uridyl phosphorothioate: chemical synthesis and enzymatic properties. Biochemistry 1979 1.65
43 Importance of exocyclic base functional groups of central core guanosines for hammerhead ribozyme activity. Biochemistry 1993 1.62
44 Phosphorothioates in molecular biology. Trends Biochem Sci 1989 1.62
45 Cleavage of phosphorothioate-substituted DNA by restriction endonucleases. J Biol Chem 1984 1.61
46 Oligonucleotide duplexes containing 2'-amino-2'-deoxycytidines: thermal stability and chemical reactivity. Nucleic Acids Res 1994 1.60
47 Age-related changes in the morphology and deformational behavior of knee joint cartilage. Arthritis Rheum 2001 1.58
48 Stereochemistry of hydrolysis by snake venom phosphodiesterase. J Biol Chem 1979 1.58
49 Dynamics of the RNA hairpin GNRA tetraloop. Biochemistry 2000 1.47
50 Synthesis of d(GC) and d(CG) octamers containing alternating phosphorothioate linkages: effect of the phosphorothioate group on the B-Z transition. Biochemistry 1985 1.46
51 Hammerhead ribozyme-mediated cleavage of the long terminal repeat RNA of human immunodeficiency virus type 1. J Biol Chem 1992 1.45
52 The importance of being ribose at the cleavage site in the Tetrahymena ribozyme reaction. Biochemistry 1993 1.45
53 Investigation of enzyme mechanisms with nucleoside phosphorothioates. Angew Chem Int Ed Engl 1975 1.44
54 A study of the mechanism of T4 DNA polymerase with diastereomeric phosphorothioate analogues of deoxyadenosine triphosphate. J Biol Chem 1982 1.44
55 Contributions of 2'-hydroxyl groups of the RNA substrate to binding and catalysis by the Tetrahymena ribozyme. An energetic picture of an active site composed of RNA. Biochemistry 1993 1.44
56 Chiral phosphorothioate analogues of B-DNA. The crystal structure of Rp-d[Gp(S)CpGp(S)CpGp(S)C]. J Mol Biol 1986 1.43
57 Filter disc supported oligonucleotide synthesis by the phosphite method. Nucleic Acids Res 1984 1.43
58 2'-Fluoro- and 2'-amino-2'-deoxynucleoside 5'-triphosphates as substrates for T7 RNA polymerase. Biochemistry 1992 1.41
59 Function of specific 2'-hydroxyl groups of guanosines in a hammerhead ribozyme probed by 2' modifications. Proc Natl Acad Sci U S A 1992 1.41
60 Stereochemical course of DNA hydrolysis by nuclease S1. J Biol Chem 1983 1.41
61 The osteoporotic vertebral structure is well adapted to the loads of daily life, but not to infrequent "error" loads. Bone 2004 1.41
62 In situ measurement of articular cartilage deformation in intact femoropatellar joints under static loading. J Biomech 1999 1.40
63 Definition of osteoarthritis on MRI: results of a Delphi exercise. Osteoarthritis Cartilage 2011 1.40
64 Mg(2+)-dependent conformational changes in the hammerhead ribozyme. Biochemistry 1996 1.40
65 Change in regional cartilage morphology and joint space width in osteoarthritis participants versus healthy controls: a multicentre study using 3.0 Tesla MRI and Lyon-Schuss radiography. Ann Rheum Dis 2010 1.38
66 Generation of left-handed Z-DNA in solution and visualization in polytene chromosomes by immunofluorescence. Cold Spring Harb Symp Quant Biol 1983 1.36
67 Gender differences in knee joint cartilage thickness, volume and articular surface areas: assessment with quantitative three-dimensional MR imaging. Skeletal Radiol 2001 1.35
68 Determination of 3D cartilage thickness data from MR imaging: computational method and reproducibility in the living. Magn Reson Med 1999 1.34
69 The stereochemical course of the restriction endonuclease EcoRI-catalyzed reaction. J Biol Chem 1984 1.33
70 Interobserver reproducibility of quantitative cartilage measurements: comparison of B-spline snakes and manual segmentation. Magn Reson Imaging 1999 1.33
71 Mechanism of ribose 2'-group discrimination by an RNA polymerase. Biochemistry 1997 1.32
72 Crystal and molecular structure of adenosine 5'-O-phosphorothioate O-p-nitrophenyl ester (Sp diastereomer). Substrate stereospecificity of snake venom phosphodiesterase. Eur J Biochem 1979 1.29
73 Stereochemistry of the guanyl nucleotide binding site of transducin probed by phosphorothioate analogues of GTP and GDP. Biochemistry 1985 1.29
74 Polynucleotides containing 2'-amino-2'-deoxyribose and 2'-azido-2'-deoxyribose. Biochemistry 1973 1.27
75 Premorbid knee osteoarthritis is not characterised by diffuse thinness: the Framingham Osteoarthritis Study. Ann Rheum Dis 2008 1.27
76 Left-handed helical conformation of poly[d(A-m5C).d(G-T)]. Nature 1983 1.27
77 Inter-domain cross-linking and molecular modelling of the hairpin ribozyme. J Mol Biol 1997 1.25
78 Knee cartilage of spinal cord-injured patients displays progressive thinning in the absence of normal joint loading and movement. Arthritis Rheum 2002 1.25
79 Subregional femorotibial cartilage morphology in women--comparison between healthy controls and participants with different grades of radiographic knee osteoarthritis. Osteoarthritis Cartilage 2009 1.24
80 Feasibility of T and Z scores from magnetic resonance imaging data for quantification of cartilage loss in osteoarthritis. Arthritis Rheum 2003 1.24
81 The association of prevalent medial meniscal pathology with cartilage loss in the medial tibiofemoral compartment over a 2-year period. Osteoarthritis Cartilage 2009 1.22
82 Study of a hammerhead ribozyme containing 2'-modified adenosine residues. Biochemistry 1991 1.21
83 Women have thinner cartilage and smaller joint surfaces than men after adjustment for body height and weight. Osteoarthritis Cartilage 2007 1.21
84 Inhibition of deoxyribonucleases by phosphorothioate groups in oligodeoxyribonucleotides. Nucleic Acids Res 1988 1.21
85 Chemically modified RNA: approaches and applications. FASEB J 1993 1.20
86 Probing accessible sites for ribozymes on human acetylcholinesterase RNA. RNA 1997 1.20
87 Sensitivity to change of cartilage morphometry using coronal FLASH, sagittal DESS, and coronal MPR DESS protocols--comparative data from the Osteoarthritis Initiative (OAI). Osteoarthritis Cartilage 2009 1.19
88 Synthesis of ATP- and dATP-substituted sepharoses and their application in the purification of phage-T4-induced ribonucleotide reductase. Eur J Biochem 1972 1.19
89 Polyribonucleotides containing a phosphorothioate backbone. Eur J Biochem 1970 1.19
90 Longitudinal analysis of cartilage atrophy in the knees of patients with spinal cord injury. Arthritis Rheum 2003 1.17
91 Probing RNA tertiary structure: interhelical crosslinking of the hammerhead ribozyme. RNA 1995 1.17
92 MRI-based extended ordered values more efficiently differentiate cartilage loss in knees with and without joint space narrowing than region-specific approaches using MRI or radiography--data from the OA initiative. Osteoarthritis Cartilage 2011 1.17
93 The antiviral activity of thiophosphate-substituted polyribonucleotides in vitro and in vivo. Virology 1970 1.16
94 Assignment of resonances in the phosphorus-31 nuclear magnetic resonance spectrum of poly[d(A-T)] from phosphorothioate substitution. Biochemistry 1983 1.16
95 Quantitative determination of articular pressure in the human shoulder joint. J Shoulder Elbow Surg 2000 1.15
96 Side differences of thigh muscle cross-sectional areas and maximal isometric muscle force in bilateral knees with the same radiographic disease stage, but unilateral frequent pain - data from the osteoarthritis initiative. Osteoarthritis Cartilage 2012 1.15
97 Determinant nucleotides of yeast tRNA(Asp) interact directly with aspartyl-tRNA synthetase. Proc Natl Acad Sci U S A 1992 1.14
98 Properties of 2'-fluorothymidine-containing oligonucleotides: interaction with restriction endonuclease EcoRV. Biochemistry 1991 1.14
99 Glenohumeral translation during active and passive elevation of the shoulder - a 3D open-MRI study. J Biomech 2000 1.13
100 A single-strand specific endonuclease activity copurifies with overexpressed T5 D15 exonuclease. Nucleic Acids Res 1991 1.12
101 On the mechanism of ribonuclease A. Crystal and molecular structure of uridine 3'-O-thiophosphate methyl ester triethylammonium salt. Eur J Biochem 1974 1.12
102 MR imaging of cartilage and its repair in the knee--a review. Eur Radiol 2009 1.12
103 Effect of deoxynucleoside phosphorothioates incorporated in DNA on cleavage by restriction enzymes. J Biol Chem 1982 1.12
104 High activity and stability of hammerhead ribozymes containing 2'-modified pyrimidine nucleosides and phosphorothioates. J Biol Chem 1994 1.12
105 2'-Deoxy-2'-azidocytidine, a new inhibitor of DNA replication in mammalian cells. Eur J Biochem 1977 1.12
106 Stereochemistry of internucleotide bond formation by polynucleotide phosphorylase from Micrococcus luteus. Biochemistry 1979 1.12
107 Trabecular bone tissue strains in the healthy and osteoporotic human femur. J Bone Miner Res 2003 1.12
108 The enzymatic synthesis of thiophosphate analogs of nucleotides. Biochim Biophys Acta 1972 1.11
109 Cloning and antisense oligodeoxynucleotide inhibition of a human homolog of cdc2 required in hematopoiesis. Proc Natl Acad Sci U S A 1992 1.11
110 Polynucleotides containing 2'-chloro-2'-deoxyribose. Biochemistry 1972 1.11
111 Synthesis and characterization of diastereomers of guanosine 5'-O-(1-thiotriphosphate) and guanosine 5'-O-(2-thiotriphosphate). Biochemistry 1982 1.10
112 Stereochemical course of polymerization catalyzed by avian myeloblastosis virus reverse transcriptase. J Biol Chem 1982 1.10
113 The antiviral activity of certain thiophosphate and 2'-chloro substituted polynucleotide homopolymer duplexes. Virology 1972 1.10
114 Three-dimensional analysis of the width of the subacromial space in healthy subjects and patients with impingement syndrome. AJR Am J Roentgenol 1999 1.09
115 Three-dimensional analysis of shoulder girdle and supraspinatus motion patterns in patients with impingement syndrome. J Orthop Res 2001 1.09
116 Inhibition of gene expression with ribozymes. Cell Mol Neurobiol 1994 1.09
117 Subacromial space width changes during abduction and rotation--a 3-D MR imaging study. Surg Radiol Anat 1999 1.08
118 Topology of the GTP-binding site of adenylyl cyclase from pigeon erythrocytes. FEBS Lett 1976 1.08
119 Activity of hammerhead ribozymes containing non-nucleotidic linkers. Nucleic Acids Res 1993 1.08
120 Does cartilage volume or thickness distinguish knees with and without mild radiographic osteoarthritis? The Framingham Study. Ann Rheum Dis 2010 1.08
121 Investigation of the inhibitory role of phosphorothioate internucleotidic linkages on the catalytic activity of the restriction endonuclease EcoRV. Biochemistry 1990 1.06
122 Deformational behaviour of knee cartilage and changes in serum cartilage oligomeric matrix protein (COMP) after running and drop landing. Osteoarthritis Cartilage 2011 1.05
123 Use of novel interactive input devices for segmentation of articular cartilage from magnetic resonance images. Osteoarthritis Cartilage 2005 1.05
124 High-efficiency oligonucleotide-directed plasmid mutagenesis. Proc Natl Acad Sci U S A 1990 1.05
125 Assignment of resonances in the 31P NMR spectrum of d(GGAATTCC) by regiospecific labeling with oxygen-17. Biochemistry 1984 1.05
126 Effect of abducting and adducting muscle activity on glenohumeral translation, scapular kinematics and subacromial space width in vivo. J Biomech 2005 1.04
127 Mechanical strength of the thoracolumbar spine in the elderly: prediction from in situ dual-energy X-ray absorptiometry, quantitative computed tomography (QCT), upper and lower limb peripheral QCT, and quantitative ultrasound. Bone 2002 1.04
128 Structural analysis of trabecular bone of the proximal femur using multislice computed tomography: a comparison with dual X-ray absorptiometry for predicting biomechanical strength in vitro. Calcif Tissue Int 2006 1.03
129 Cartilage atrophy in the knees of patients after seven weeks of partial load bearing. Arthritis Rheum 2004 1.03
130 AUA-cleaving hammerhead ribozymes: attempted selection for improved cleavage. Biochemistry 1994 1.03
131 Interaction of retinal transducin with guanosine triphosphate analogues: specificity of the gamma-phosphate binding region. Biochemistry 1986 1.02
132 Elastic registration of 3D cartilage surfaces from MR image data for detecting local changes in cartilage thickness. Magn Reson Med 2000 1.02
133 The stereochemical course of the reaction catalyzed by soluble bovine lung guanylate cyclase. J Biol Chem 1983 1.02
134 Isolation of hammerhead ribozymes with altered core sequences by in vitro selection. Biochemistry 1997 1.02
135 Image-based micro-finite-element modeling for improved distal radius strength diagnosis: moving from bench to bedside. J Clin Densitom 2004 1.02
136 Direct comparison of contact areas, contact stress and subchondral mineralization in human hip joint specimens. Anat Embryol (Berl) 1997 1.01
137 Stereochemistry of enzymic phosphoryl and nucleotidyl transfer. Methods Enzymol 1982 1.01
138 Determination of the turn-off reaction for the hormone-activated adenylate cyclase. J Biol Chem 1979 1.01
139 Femoro-tibial and menisco-tibial translation patterns in patients with unilateral anterior cruciate ligament deficiency--a potential cause of secondary meniscal tears. J Orthop Res 2004 1.01
140 Osteoarthritis may not be a one-way-road of cartilage loss--comparison of spatial patterns of cartilage change between osteoarthritic and healthy knees. Osteoarthritis Cartilage 2009 1.00
141 DNA and RNA sequencing utilizing phosphorothioate chemistry. Nucleic Acids Symp Ser 1987 1.00
142 Experimental hip fracture load can be predicted from plain radiography by combined analysis of trabecular bone structure and bone geometry. Osteoporos Int 2007 0.99
143 Comparison of 1-year vs 2-year change in regional cartilage thickness in osteoarthritis results from 346 participants from the Osteoarthritis Initiative. Osteoarthritis Cartilage 2010 0.99
144 Stereochemical course of the reaction catalyzed by guanylate cyclase from bovine retinal rod outer segments. J Biol Chem 1990 0.99
145 Magnetic resonance-based motion analysis of the shoulder during elevation. Clin Orthop Relat Res 2000 0.99
146 Direct comparison of fixed flexion, radiography and MRI in knee osteoarthritis: responsiveness data from the Osteoarthritis Initiative. Osteoarthritis Cartilage 2012 0.99
147 RNA mediated formation of a phosphorothioate diester bond. Biochem Biophys Res Commun 1988 0.98
148 Detection of osteoporotic vertebral fractures using multidetector CT. Osteoporos Int 2005 0.98
149 Automated 3D trabecular bone structure analysis of the proximal femur--prediction of biomechanical strength by CT and DXA. Osteoporos Int 2009 0.98
150 Thiophosphate-analogues and 1-N-oxides of ATP and ADP in mitochondrial translocation and phosphoryl-transfer reactions. Eur J Biochem 1973 0.98
151 The relationship between knee adduction moment and cartilage and meniscus morphology in women with osteoarthritis. Osteoarthritis Cartilage 2010 0.98
152 Stereochemistry of the mammalian adenylate cyclase reaction. J Biol Chem 1981 0.98
153 Guanosine 5'-[beta-thio]triphosphate selectively activates calcium signaling in mast cells. Proc Natl Acad Sci U S A 1991 0.98
154 Intracellular stimulation of mast cells with guanine nucleotides mimic antigenic stimulation. FEBS Lett 1987 0.98
155 Determination of 2'-hydroxyl and phosphate groups important for aminoacylation of Escherichia coli tRNAAsp: a nucleotide analogue interference study. RNA 1998 0.98
156 Strand specific cleavage of phosphorothioate-containing DNA by reaction with restriction endonucleases in the presence of ethidium bromide. Nucleic Acids Res 1988 0.98
157 Purine and pyrimidine nucleotides potentiate activation of NADPH oxidase and degranulation by chemotactic peptides and induce aggregation of human neutrophils via G proteins. Eur J Biochem 1989 0.98
158 Validation of cartilage volume and thickness measurements in the human shoulder with quantitative magnetic resonance imaging. Osteoarthritis Cartilage 2003 0.98
159 The distribution of cartilage thickness in the knee-joints of old-aged individuals -- measurement by A-mode ultrasound. Clin Biomech (Bristol, Avon) 1998 0.97
160 Rapid high-efficiency site-directed mutagenesis by the phosphorothioate approach. Biotechniques 1992 0.96
161 Stereochemistry of the transesterification step of ribonuclease T 1 . Biochemistry 1972 0.96
162 A stereospecifically 18O-labelled deoxydinucleoside phosphate block for incorporation into an oligonucleotide. Nucleic Acids Res 1983 0.96
163 One-year change in radiographic joint space width in patients with unilateral joint space narrowing: data from the Osteoarthritis Initiative. Arthritis Care Res (Hoboken) 2010 0.95
164 The influence of exocyclic substituents of purine bases on DNA curvature. Proc Natl Acad Sci U S A 1987 0.95
165 Sequence specificity of the hammerhead ribozyme revisited; the NHH rule. Nucleic Acids Res 1998 0.95
166 Correlation between single-slice muscle anatomical cross-sectional area and muscle volume in thigh extensors, flexors and adductors of perimenopausal women. Eur J Appl Physiol 2010 0.95
167 A substrate radical intermediate in the reaction between ribonucleotide reductase from Escherichia coli and 2'-azido-2'-deoxynucleoside diphosphates. J Biol Chem 1983 0.95
168 Precision of tibial cartilage morphometry with a coronal water-excitation MR sequence. Eur Radiol 2000 0.95
169 Accuracy of quantitative magnetic resonance imaging in the detection of ex vivo focal cartilage defects. Ann Rheum Dis 2005 0.94
170 From joint anatomy to clinical outcomes in osteoarthritis and cartilage repair: summary of the fifth annual osteoarthritis imaging workshop. Osteoarthritis Cartilage 2011 0.94
171 Enhanced in vitro inhibition of HIV-1 replication by 3'-fluoro-3'-deoxythymidine compared to several other nucleoside analogs. AIDS Res Hum Retroviruses 1988 0.94
172 Relation of regional articular cartilage morphometry and meniscal position by MRI to joint space width in knee radiographs. Osteoarthritis Cartilage 2009 0.94
173 Modification of an essential arginine in Escherichia coli DNA-dependent RNA polymerase. FEBS Lett 1976 0.94
174 A non-invasive technique for 3-dimensional assessment of articular cartilage thickness based on MRI. Part 2: Validation using CT arthrography. Magn Reson Imaging 1997 0.94
175 A facile method for the preparation of N6-substituted ATP-Sepharose. Nucleic Acids Res 1975 0.94
176 Contribution of regional 3D meniscus and cartilage morphometry by MRI to joint space width in fixed flexion knee radiography--a between-knee comparison in subjects with unilateral joint space narrowing. Eur J Radiol 2013 0.94
177 Validation of high-resolution water-excitation magnetic resonance imaging for quantitative assessment of thin cartilage layers. Osteoarthritis Cartilage 2000 0.94
178 Impact of bone density on distal radius fracture patterns and comparison between five different fracture classifications. J Orthop Trauma 2003 0.94
179 Mechanistic studies on deoxyribonucleic acid dependent ribonucleic acid polymerase from Escherichia coli using phosphorothioate analogues. 2. The elongation reaction. Biochemistry 1979 0.93
180 The subcellular localization and length of hammerhead ribozymes determine efficacy in human cells. Nucleic Acids Res 1997 0.93
181 An MR-based technique for quantifying the deformation of articular cartilage during mechanical loading in an intact cadaver joint. Magn Reson Med 1998 0.93
182 Studies on the toxicity and antiviral activity of various polynucleotides. Antimicrob Agents Chemother 1973 0.93
183 Adenosine 3',5'-cyclic phosphorothioate: synthesis and biological properties. Biochemistry 1974 0.93
184 A technique for 3D in vivo quantification of proton density and magnetization transfer coefficients of knee joint cartilage. Osteoarthritis Cartilage 2000 0.93
185 In vitro selection of a purine nucleotide-specific hammerheadlike ribozyme. Proc Natl Acad Sci U S A 1998 0.93
186 Comparison of knee joint cartilage thickness in triathletes and physically inactive volunteers based on magnetic resonance imaging and three-dimensional analysis. Am J Sports Med 2000 0.93
187 The newt ribozyme is part of a riboprotein complex. Proc Natl Acad Sci U S A 1997 0.93
188 Forces involved ithe conformational stability of nucleic acids. Nature 1969 0.93
189 Does thoracic or lumbar spine bone architecture predict vertebral failure strength more accurately than density? Osteoporos Int 2007 0.93
190 Mechanistic studies on deoxyribonucleic acid dependent ribonucleic acid polymerase from Escherichia coli using phosphorothioate analogues. 1. Initiation and pyrophosphate exchange reactions. Biochemistry 1979 0.92
191 Assessment of normal patellar cartilage volume and thickness using MRI: an analysis of currently available pulse sequences. Skeletal Radiol 1996 0.92
192 Cyclic AMP-induced pH changes in Dictyostelium discoideum and their control by calcium. Biochim Biophys Acta 1978 0.92
193 Quantitative MR imaging evaluation of the cartilage thickness and subchondral bone area in patients with ACL-reconstructions 7 years after surgery. Osteoarthritis Cartilage 2009 0.91
194 Sustained clinical and structural benefit after joint distraction in the treatment of severe knee osteoarthritis. Osteoarthritis Cartilage 2013 0.91
195 ATP-and dATP-substituted agaroses and the purification of ribonucleotide reductases. Methods Enzymol 1974 0.91
196 Synthesis and reactions of 6-methylsulfonyl-9-beta-D-ribofuranosylpurine. J Org Chem 1975 0.91
197 Antiviral, antimetabolic and antineoplastic activities of 2'- or 3'-amino or -azido-substituted deoxyribonucleosides. Biochem Pharmacol 1980 0.91
198 Frequency and spatial distribution of cartilage thickness change in knee osteoarthritis and its relation to clinical and radiographic covariates - data from the osteoarthritis initiative. Osteoarthritis Cartilage 2012 0.91
199 [Beta, beta, beta-trichlor-ethanol as phosphoric acid protection groups for nucleotides]. Chem Ber 1967 0.91
200 Guanylylimidodiphosphate and its interaction with amino acid polymerization factors. Biochem Biophys Res Commun 1971 0.91
201 Tibial coverage, meniscus position, size and damage in knees discordant for joint space narrowing - data from the Osteoarthritis Initiative. Osteoarthritis Cartilage 2012 0.91
202 [Three-dimensional thickness and volume measurements of the knee joint cartilage using MRI: validation in an anatomical specimen by CT arthrography]. Rofo 1997 0.91
203 Hydroxyurea increases the phosphorylation of 3'-fluorothymidine and 3'-azidothymidine in CEM cells. Eur J Biochem 1989 0.90
204 Nucleic acid enzymes. Curr Opin Chem Biol 1999 0.90
205 Effects of joint unloading and reloading on human cartilage morphology and function, muscle cross-sectional areas, and bone density - a quantitative case report. J Musculoskelet Neuronal Interact 2006 0.90
206 Heart failure resulting from giant left atrial synovial sarcoma metastasis. Thorac Cardiovasc Surg 2011 0.90
207 Inhibition of human immunodeficiency virus 1 reverse transcriptase by 3'-azidothymidine triphosphate. Eur J Biochem 1990 0.90
208 Multiple conformational states of the hammerhead ribozyme, broad time range of relaxation and topology of dynamics. Nucleic Acids Res 2000 0.90
209 Synthesis of oligonucleotides by use of phosphoric triesters. Angew Chem Int Ed Engl 1967 0.90
210 Human osteogenesis involves differentiation-dependent increases in the morphogenically active 3' alternative splicing variant of acetylcholinesterase. Mol Cell Biol 1999 0.89
211 Presence, location, type and size of denuded areas of subchondral bone in the knee as a function of radiographic stage of OA - data from the OA initiative. Osteoarthritis Cartilage 2010 0.89
212 Site specific labelling of sugar residues in oligoribonucleotides: reactions of aliphatic isocyanates with 2' amino groups. Nucleic Acids Res 1996 0.89
213 Recent developments in the hammerhead ribozyme field. Nucleic Acids Res 1998 0.89
214 Action of restriction endonucleases on phosphorothioate DNA. Biochem Soc Trans 1986 0.89
215 RNA cleavage by small catalytic RNAs. Curr Opin Struct Biol 1995 0.89
216 Optimization and validation of a rapid high-resolution T1-w 3D FLASH water excitation MRI sequence for the quantitative assessment of articular cartilage volume and thickness. Magn Reson Imaging 2001 0.89
217 Stereochemistry of internucleotidic bond formation by tRNA nucleotidyltransferase from baker's yeast. Biochemistry 1977 0.89
218 Antisense oligonucleotide inhibition of acetylcholinesterase gene expression induces progenitor cell expansion and suppresses hematopoietic apoptosis ex vivo. Proc Natl Acad Sci U S A 1994 0.88
219 Gender differences in trabecular bone architecture of the distal radius assessed with magnetic resonance imaging and implications for mechanical competence. Osteoporos Int 2005 0.88
220 Lipid phosphorylation in chloroplast envelopes. Evidence for galactolipid CTP-dependent kinase activities. J Biol Chem 2000 0.88
221 [Selective phosphorylation of nucleosides]. Chem Ber 1968 0.88
222 Manipulations of cholinesterase gene expression modulate murine megakaryocytopoiesis in vitro. Mol Cell Biol 1990 0.88
223 Phosphorothioate-containing RNAs show mRNA activity in the prokaryotic translation systems in vitro. Nucleic Acids Res 1991 0.88
224 In vivo contact areas of the knee in patients with patellar subluxation. J Biomech 2005 0.88
225 Interaction of substrate analogues with Escherichia coli DNA-dependent RNA polymerase. Eur J Biochem 1976 0.88
226 HIV-1 LTR as a target for synthetic ribozyme-mediated inhibition of gene expression: site selection and inhibition in cell culture. Nucleic Acids Res 2000 0.88
227 Structure, strain and function of the transverse acetabular ligament. Acta Anat (Basel) 1996 0.87
228 An in vivo technique for determining 3D muscular moment arms in different joint positions and during muscular activation - application to the supraspinatus. Clin Biomech (Bristol, Avon) 2001 0.87
229 Correlation of femoral and lumbar DXA and calcaneal ultrasound, measured in situ with intact soft tissues, with the in vitro failure loads of the proximal femur. Osteoporos Int 1998 0.87
230 Stereochemistry of hydrolysis of adenosine 3':5'-cyclic phosphorothioate by the cyclic phosphodiesterase from beef heart. J Biol Chem 1979 0.87
231 Equivalence and precision of knee cartilage morphometry between different segmentation teams, cartilage regions, and MR acquisitions. Osteoarthritis Cartilage 2012 0.87
232 Correlation of thoracic and lumbar vertebral failure loads with in situ vs. ex situ dual energy X-ray absorptiometry. J Biomech 2001 0.86
233 Ribozyme-mediated RNA degradation in nuclei suspension. Nucleic Acids Res 1995 0.86
234 Designing ribozymes for the inhibition of gene expression. Trends Biotechnol 1998 0.86
235 Inhibition of the restriction endonuclease BanII using modified DNA substrates. Determination of phosphate residues critical for the formation of an active enzyme-DNA complex. J Biol Chem 1990 0.86
236 Precision of high-resolution dual energy X-ray absorptiometry of bone mineral status and body composition in small animal models. Eur Cell Mater 2001 0.86
237 The thickness of the subchondral plate and its correlation with the thickness of the uncalcified articular cartilage in the human patella. Anat Embryol (Berl) 1995 0.86
238 Antisense technologies have a future fighting neurodegenerative diseases. Antisense Nucleic Acid Drug Dev 1999 0.86
239 Technical considerations for microstructural analysis of human trabecular bone from specimens excised from various skeletal sites. Calcif Tissue Int 2004 0.85
240 Prediction of vertebral failure loads from spinal and femoral dual-energy X-ray absorptiometry, and calcaneal ultrasound: an in situ analysis with intact soft tissues. Bone 1998 0.85
241 Femorotibial cartilage morphology: reproducibility of different metrics and femoral regions, and sensitivity to change in disease. Cells Tissues Organs 2010 0.85
242 In situ femoral dual-energy X-ray absorptiometry related to ash weight, bone size and density, and its relationship with mechanical failure loads of the proximal femur. Osteoporos Int 2000 0.85
243 In vitro selection of hammerhead ribozymes containing a bulged nucleotide in stem II. Nucleic Acids Res 1996 0.85
244 Thickness distribution of the subchondral mineralization zone of the trochlear notch and its correlation with the cartilage thickness: an expression of functional adaptation to mechanical stress acting on the humeroulnar joint? Anat Rec 1997 0.85
245 Allometric relationships between knee cartilage volume, thickness, surface area and body dimensions. Osteoarthritis Cartilage 2007 0.85
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