Published in J Biol Chem on December 31, 2008
"Go upstream, young man": lessons learned from the p38 saga. Ann Rheum Dis (2010) 1.48
Plasma concentrations of inflammatory cytokines rise rapidly during ECMO-related SIRS due to the release of preformed stores in the intestine. Lab Invest (2009) 1.40
The blood-brain barrier, chemokines and multiple sclerosis. Biochim Biophys Acta (2010) 1.40
Chronic parenteral nutrition induces hepatic inflammation, steatosis, and insulin resistance in neonatal pigs. J Nutr (2010) 1.16
Apolipoprotein A-I mimetic 4F alters the function of human monocyte-derived macrophages. Am J Physiol Cell Physiol (2010) 1.12
Gut mucosal injury in neonates is marked by macrophage infiltration in contrast to pleomorphic infiltrates in adult: evidence from an animal model. Am J Physiol Gastrointest Liver Physiol (2012) 1.06
Chlorine gas exposure causes systemic endothelial dysfunction by inhibiting endothelial nitric oxide synthase-dependent signaling. Am J Respir Cell Mol Biol (2010) 1.06
Focal adhesion kinase regulation of mechanotransduction and its impact on endothelial cell functions. Microvasc Res (2011) 0.98
Smad7 inhibits autocrine expression of TGF-β2 in intestinal epithelial cells in baboon necrotizing enterocolitis. Am J Physiol Gastrointest Liver Physiol (2012) 0.97
Extracorporeal membrane oxygenation causes loss of intestinal epithelial barrier in the newborn piglet. Pediatr Res (2010) 0.89
High Pulsatility Flow Induces Acute Endothelial Inflammation through Overpolarizing Cells to Activate NF-κB. Cardiovasc Eng Technol (2013) 0.88
Activation of NF-kappaB by fluid shear stress, but not TNF-alpha, requires focal adhesion kinase in osteoblasts. Bone (2010) 0.87
Preterm human milk contains a large pool of latent TGF-β, which can be activated by exogenous neuraminidase. Am J Physiol Gastrointest Liver Physiol (2013) 0.86
Developmental changes in circulating IL-8/CXCL8 isoforms in neonates. Cytokine (2009) 0.85
Kidney injury accelerates cystogenesis via pathways modulated by heme oxygenase and complement. J Am Soc Nephrol (2012) 0.84
Novel high-throughput in vitro model for identifying hemodynamic-induced inflammatory mediators of cerebral aneurysm formation. Hypertension (2014) 0.80
Amniotic fluid-borne hepatocyte growth factor protects rat pups against experimental necrotizing enterocolitis. Am J Physiol Gastrointest Liver Physiol (2014) 0.79
Transforming growth factor-β2 is sequestered in preterm human milk by chondroitin sulfate proteoglycans. Am J Physiol Gastrointest Liver Physiol (2015) 0.77
Dynamic deformability of sickle red blood cells in microphysiological flow. Technology (Singap World Sci) (2016) 0.76
Receptor activator of NF-κB ligand induces cell adhesion and integrin α2 expression via NF-κB in head and neck cancers. Sci Rep (2016) 0.75
Sickle cell disease biochip: a functional red blood cell adhesion assay for monitoring sickle cell disease. Transl Res (2016) 0.75
Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity. Annu Rev Immunol (2000) 20.70
Chemokines--chemotactic cytokines that mediate inflammation. N Engl J Med (1998) 12.80
Traffic signals on endothelium for lymphocyte recirculation and leukocyte emigration. Annu Rev Physiol (1995) 7.16
IL-8 directly enhanced endothelial cell survival, proliferation, and matrix metalloproteinases production and regulated angiogenesis. J Immunol (2003) 4.64
Transcytosis and surface presentation of IL-8 by venular endothelial cells. Cell (1997) 4.44
Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1). EMBO J (2003) 4.22
Quantitative investigations of the adhesiveness of circulating polymorphonuclear leucocytes to blood vessel walls. J Physiol (1972) 4.04
Molecular basis of the effects of shear stress on vascular endothelial cells. J Biomech (2005) 3.77
The structure and function of the endothelial glycocalyx layer. Annu Rev Biomed Eng (2007) 3.40
The role of chemokines in neutrophil biology. Front Biosci (2008) 3.10
The microcirculation and inflammation: modulation of leukocyte-endothelial cell adhesion. J Leukoc Biol (1994) 2.54
Inhibitors of NF-kappaB signaling: 785 and counting. Oncogene (2006) 2.33
Hemodynamic forces are complex regulators of endothelial gene expression. FASEB J (1995) 2.23
Fluid mechanics of vascular systems, diseases, and thrombosis. Annu Rev Biomed Eng (1999) 2.20
Differential expression and activation of p38 mitogen-activated protein kinase alpha, beta, gamma, and delta in inflammatory cell lineages. J Immunol (1999) 2.07
Apoptosis signaling pathway in T cells is composed of ICE/Ced-3 family proteases and MAP kinase kinase 6b. Immunity (1997) 2.04
MSK1 activity is controlled by multiple phosphorylation sites. Biochem J (2005) 1.72
Fluid shear stress inhibits TNF-alpha activation of JNK but not ERK1/2 or p38 in human umbilical vein endothelial cells: Inhibitory crosstalk among MAPK family members. Proc Natl Acad Sci U S A (2001) 1.67
The role of the Grb2-p38 MAPK signaling pathway in cardiac hypertrophy and fibrosis. J Clin Invest (2003) 1.61
Human cytomegalovirus replicates abortively in polymorphonuclear leukocytes after transfer from infected endothelial cells via transient microfusion events. J Virol (2000) 1.53
Rho proteins and the p38-MAPK pathway are important mediators for LPS-induced interleukin-8 expression in human endothelial cells. Blood (2000) 1.48
Mucosal IL-8 and TGF-beta recruit blood monocytes: evidence for cross-talk between the lamina propria stroma and myeloid cells. J Leukoc Biol (2006) 1.47
p38 MAPK-induced nuclear factor-kappaB activity is required for skeletal muscle differentiation: role of interleukin-6. Mol Biol Cell (2004) 1.44
Regulated expression of focal adhesion kinase-related nonkinase, the autonomously expressed C-terminal domain of focal adhesion kinase. Mol Cell Biol (1999) 1.42
Leukocyte transendothelial migration: a junctional affair. Semin Immunol (2002) 1.39
Regulation of inducible nitric oxide synthase in proinflammatory cytokine-stimulated human primary astrocytes. Free Radic Biol Med (2005) 1.36
The role of chemokines in human cardiovascular pathology: enhanced biological insights. Atherosclerosis (2002) 1.35
Contributions of capillary pathway size and neutrophil deformability to neutrophil transit through rabbit lungs. J Appl Physiol (1985) (1994) 1.34
Shear stress-induced changes in atherosclerotic plaque composition are modulated by chemokines. J Clin Invest (2007) 1.33
Chemokines in rapid leukocyte adhesion triggering and migration. Semin Immunol (2002) 1.31
Upregulation of superoxide dismutase and nitric oxide synthase mediates the apoptosis-suppressive effects of shear stress on endothelial cells. Arterioscler Thromb Vasc Biol (1999) 1.31
FGF-10 is decreased in bronchopulmonary dysplasia and suppressed by Toll-like receptor activation. Am J Physiol Lung Cell Mol Physiol (2006) 1.23
Shear stress-mediated chromatin remodeling provides molecular basis for flow-dependent regulation of gene expression. Circ Res (2003) 1.22
Role of cell surface heparan sulfate proteoglycans in endothelial cell migration and mechanotransduction. J Cell Physiol (2005) 1.20
The effects and comparative differences of neutrophil specific chemokines on neutrophil chemotaxis of the neonate. Cytokine (2004) 1.13
Laminar shear stress acts as a switch to regulate divergent functions of NF-kappaB in endothelial cells. FASEB J (2007) 1.13
Regulation of IkappaB kinase and NF-kappaB in contracting adult rat skeletal muscle. Am J Physiol Cell Physiol (2005) 1.11
Endothelial cell-matrix interactions. Microsc Res Tech (2003) 1.09
Expression of alphav integrins and vitronectin receptor identity in breast cancer cells. Br J Cancer (1998) 1.08
Low shear stress preferentially enhances IKK activity through selective sources of ROS for persistent activation of NF-kappaB in endothelial cells. Am J Physiol Cell Physiol (2006) 1.01
Biochemical evidence for a homophilic interaction of the alpha 3 beta 1 integrin. J Biol Chem (1993) 1.00
Cytomegalovirus blocks intestinal stroma-induced down-regulation of macrophage HIV-1 infection. J Leukoc Biol (2006) 0.97
Rheology of the microcirculation. Clin Hemorheol Microcirc (2003) 0.95
ELR+ CXC chemokines in human milk. Cytokine (2003) 0.91
Activation of NF-kappaB nuclear transcription factor by flow in human endothelial cells. Biochim Biophys Acta (2003) 0.87
Low shear stress-induced interleukin-8 mRNA expression in endothelial cells is mechanotransduced by integrins and the cytoskeleton. Endothelium (2007) 0.85
A novel leukocyte chemotactic and activating cytokine, interleukin-8 (IL-8). Cancer Treat Res (1995) 0.82
Fluid shear stress suppresses interleukin 8 production by vascular endothelial cells. Biorheology (2001) 0.81
Effects of laminar shear stress on IL-8 mRNA expression in endothelial cells. Biorheology (2003) 0.78
Neutrophil rheology and transit through capillaries and sinusoids. Am J Respir Crit Care Med (1999) 0.78
IL-8/CXC ligand 8 survives neonatal gastric digestion as a result of intrinsic aspartyl proteinase resistance. Pediatr Res (2004) 0.77
Microcirculatory hematocrit and blood flow. J Theor Biol (1988) 0.77
[Effects of laminar shear stress on IL-8 mRNA expression in endothelial cells]. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi (2001) 0.76
Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation. Nat Med (2003) 8.95
Cytoprotective effects of nitrite during in vivo ischemia-reperfusion of the heart and liver. J Clin Invest (2005) 4.14
Inhaled NO accelerates restoration of liver function in adults following orthotopic liver transplantation. J Clin Invest (2007) 3.22
Oxidative stress in the pathogenesis of skin disease. J Invest Dermatol (2006) 3.16
Enzymatic function of hemoglobin as a nitrite reductase that produces NO under allosteric control. J Clin Invest (2005) 3.08
SNO-hemoglobin is not essential for red blood cell-dependent hypoxic vasodilation. Nat Med (2008) 3.02
The emerging biology of the nitrite anion. Nat Chem Biol (2005) 2.88
Hydrogen sulfide mediates the vasoactivity of garlic. Proc Natl Acad Sci U S A (2007) 2.77
Hypoxia, red blood cells, and nitrite regulate NO-dependent hypoxic vasodilation. Blood (2005) 2.76
Clinical risk factors for portopulmonary hypertension. Hepatology (2008) 2.62
Mycobacterium tuberculosis DosS is a redox sensor and DosT is a hypoxia sensor. Proc Natl Acad Sci U S A (2007) 2.55
The reaction between nitrite and deoxyhemoglobin. Reassessment of reaction kinetics and stoichiometry. J Biol Chem (2005) 2.34
Pulmonary vascular complications of liver disease. Am J Respir Crit Care Med (2012) 2.33
Nitrated fatty acids: Endogenous anti-inflammatory signaling mediators. J Biol Chem (2006) 2.31
Nitrate and nitrite in biology, nutrition and therapeutics. Nat Chem Biol (2009) 2.29
The Alabama Preterm Birth Study: umbilical cord blood Ureaplasma urealyticum and Mycoplasma hominis cultures in very preterm newborn infants. Am J Obstet Gynecol (2008) 2.21
Nitrite as a vascular endocrine nitric oxide reservoir that contributes to hypoxic signaling, cytoprotection, and vasodilation. Am J Physiol Heart Circ Physiol (2006) 2.17
Thy-1 as a regulator of cell-cell and cell-matrix interactions in axon regeneration, apoptosis, adhesion, migration, cancer, and fibrosis. FASEB J (2006) 2.15
Cost-effectiveness of screening for hepatopulmonary syndrome in liver transplant candidates. Liver Transpl (2007) 2.13
The biochemistry of nitric oxide, nitrite, and hemoglobin: role in blood flow regulation. Free Radic Biol Med (2004) 2.12
Emerging concepts in the pathogenesis of lung fibrosis. Am J Pathol (2009) 2.05
Bacterial vaginosis assessed by gram stain and diminished colonization resistance to incident gonococcal, chlamydial, and trichomonal genital infection. J Infect Dis (2010) 2.02
Polarographic measurement of hydrogen sulfide production and consumption by mammalian tissues. Anal Biochem (2005) 1.97
Association of antenatal corticosteroids with mortality and neurodevelopmental outcomes among infants born at 22 to 25 weeks' gestation. JAMA (2011) 1.92
Inhalation of nitric oxide prevents ischemic brain damage in experimental stroke by selective dilatation of collateral arterioles. Circ Res (2011) 1.91
Basal cell carcinoma chemoprevention with nonsteroidal anti-inflammatory drugs in genetically predisposed PTCH1+/- humans and mice. Cancer Prev Res (Phila) (2010) 1.91
Chronic sodium nitrite therapy augments ischemia-induced angiogenesis and arteriogenesis. Proc Natl Acad Sci U S A (2008) 1.87
Diagnosis and management of clinical chorioamnionitis. Clin Perinatol (2010) 1.84
An official American Thoracic Society clinical practice guideline: classification, evaluation, and management of childhood interstitial lung disease in infancy. Am J Respir Crit Care Med (2013) 1.84
Periodontal disease and upper genital tract inflammation in early spontaneous preterm birth. Obstet Gynecol (2004) 1.78
A mitochondria-targeted S-nitrosothiol modulates respiration, nitrosates thiols, and protects against ischemia-reperfusion injury. Proc Natl Acad Sci U S A (2009) 1.78
Fatty acid transduction of nitric oxide signaling. Nitrolinoleic acid is a hydrophobically stabilized nitric oxide donor. J Biol Chem (2005) 1.75
Thy-1, a versatile modulator of signaling affecting cellular adhesion, proliferation, survival, and cytokine/growth factor responses. Biochim Biophys Acta (2006) 1.73
Effects of sodium nitrite on ischemia-reperfusion injury in the rat kidney. Am J Physiol Renal Physiol (2005) 1.73
Quantification of activation patterns during ventricular fibrillation in open-chest porcine left ventricle and septum. Heart Rhythm (2005) 1.72
Vulvovaginal symptoms in women with bacterial vaginosis. Obstet Gynecol (2004) 1.72
CP-31398 restores mutant p53 tumor suppressor function and inhibits UVB-induced skin carcinogenesis in mice. J Clin Invest (2007) 1.71
Dietary intake of selected nutrients affects bacterial vaginosis in women. J Nutr (2007) 1.68
Chemical ablation of the Purkinje system causes early termination and activation rate slowing of long-duration ventricular fibrillation in dogs. Am J Physiol Heart Circ Physiol (2008) 1.66
A longitudinal study of vaginal douching and bacterial vaginosis--a marginal structural modeling analysis. Am J Epidemiol (2008) 1.63
Transduction of NO-bioactivity by the red blood cell in sepsis: novel mechanisms of vasodilation during acute inflammatory disease. Blood (2004) 1.61
Genetic risk factors for hepatopulmonary syndrome in patients with advanced liver disease. Gastroenterology (2010) 1.60
Thy-1 promoter hypermethylation: a novel epigenetic pathogenic mechanism in pulmonary fibrosis. Am J Respir Cell Mol Biol (2008) 1.58
Pulmonary complications in chronic liver disease. Hepatology (2014) 1.57
Vasoactivity of S-nitrosohemoglobin: role of oxygen, heme, and NO oxidation states. Blood (2003) 1.56
Health-related quality of life and survival in liver transplant candidates. Liver Transpl (2010) 1.55
Enhanced myofibroblastic differentiation and survival in Thy-1(-) lung fibroblasts. Am J Respir Cell Mol Biol (2006) 1.54
Solution structure of the MAPK phosphatase PAC-1 catalytic domain. Insights into substrate-induced enzymatic activation of MKP. Structure (2003) 1.54
Future directions in idiopathic pulmonary fibrosis research. An NHLBI workshop report. Am J Respir Crit Care Med (2014) 1.54
Transmural recording of shock potential gradient fields, early postshock activations, and refibrillation episodes associated with external defibrillation of long-duration ventricular fibrillation in swine. Heart Rhythm (2008) 1.52
Emerging concepts in antibiotic prophylaxis for cesarean delivery: a systematic review. Obstet Gynecol (2009) 1.48
Mucosal IL-8 and TGF-beta recruit blood monocytes: evidence for cross-talk between the lamina propria stroma and myeloid cells. J Leukoc Biol (2006) 1.47
Altered DNA methylation profile in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med (2012) 1.47
Prospective evaluation of outcomes and predictors of mortality in patients with hepatopulmonary syndrome undergoing liver transplantation. Hepatology (2003) 1.46
The cost-effectiveness of hepatitis A vaccination in patients with chronic hepatitis C viral infection in the United States. Am J Gastroenterol (2002) 1.46
Hydrogen sulfide mediates vasoactivity in an O2-dependent manner. Am J Physiol Heart Circ Physiol (2007) 1.45
Genetic risk factors for portopulmonary hypertension in patients with advanced liver disease. Am J Respir Crit Care Med (2009) 1.44
Serial pulse oximetry in hepatopulmonary syndrome. Dig Dis Sci (2011) 1.44
TGF-β2 suppresses macrophage cytokine production and mucosal inflammatory responses in the developing intestine. Gastroenterology (2010) 1.44
Modulation of pulmonary endothelial endothelin B receptor expression and signaling: implications for experimental hepatopulmonary syndrome. Am J Physiol Lung Cell Mol Physiol (2007) 1.43
Hepatopulmonary syndrome and portopulmonary hypertension: a report of the multicenter liver transplant database. Liver Transpl (2004) 1.42
Multiple treatment approach to limit cardiac ischemia-reperfusion injury. Ann Thorac Surg (2005) 1.41
Metabolic and cardiac signaling effects of inhaled hydrogen sulfide and low oxygen in male rats. J Appl Physiol (1985) (2012) 1.41
Plasma concentrations of inflammatory cytokines rise rapidly during ECMO-related SIRS due to the release of preformed stores in the intestine. Lab Invest (2009) 1.40
Punica granatum (pomegranate) flower extract possesses potent antioxidant activity and abrogates Fe-NTA induced hepatotoxicity in mice. Food Chem Toxicol (2006) 1.40
Probiotic bacteria induce maturation of intestinal claudin 3 expression and barrier function. Am J Pathol (2011) 1.38
Evaluation of antioxidant activity of Cassia siamea flowers. J Ethnopharmacol (2006) 1.37
The hepatopulmonary syndrome. J Hepatol (2006) 1.37
Depletion of plasmacytoid dendritic cells inhibits tumor growth and prevents bone metastasis of breast cancer cells. J Immunol (2012) 1.36
Oxidative modification of nuclear mitogen-activated protein kinase phosphatase 1 is involved in transforming growth factor beta1-induced expression of plasminogen activator inhibitor 1 in fibroblasts. J Biol Chem (2010) 1.36
New consensus definition of acute kidney injury accurately predicts 30-day mortality in patients with cirrhosis and infection. Gastroenterology (2013) 1.35
Thy-1 expression regulates the ability of rat lung fibroblasts to activate transforming growth factor-beta in response to fibrogenic stimuli. Am J Pathol (2004) 1.33
Activation patterns of Purkinje fibers during long-duration ventricular fibrillation in an isolated canine heart model. Circulation (2007) 1.29
Epigenetic regulation of thy-1 by histone deacetylase inhibitor in rat lung fibroblasts. Am J Respir Cell Mol Biol (2010) 1.29
Cyclooxygenase-2 expression in murine and human nonmelanoma skin cancers: implications for therapeutic approaches. Photochem Photobiol (2002) 1.28
Hemoglobin oxygen fractional saturation regulates nitrite-dependent vasodilation of aortic ring bioassays. Am J Physiol Heart Circ Physiol (2007) 1.28
Nanotransducers in cellular redox signaling: modification of thiols by reactive oxygen and nitrogen species. Trends Biochem Sci (2002) 1.27
Evolution of activation patterns during long-duration ventricular fibrillation in dogs. Am J Physiol Heart Circ Physiol (2004) 1.27
Choriodecidual infection and preterm birth. Nutr Rev (2002) 1.26
Role of p38 MAPK in UVB-induced inflammatory responses in the skin of SKH-1 hairless mice. J Invest Dermatol (2005) 1.26
Cryptorchidism: diagnosis, treatment, and long-term prognosis. Urol Clin North Am (2004) 1.26
Thy-1-integrin alphav beta5 interactions inhibit lung fibroblast contraction-induced latent transforming growth factor-beta1 activation and myofibroblast differentiation. J Biol Chem (2010) 1.25
Tumor necrosis factor and tuberculosis. J Investig Dermatol Symp Proc (2007) 1.25
Pulmonary angiogenesis in a rat model of hepatopulmonary syndrome. Gastroenterology (2008) 1.23
Intercellular adhesion molecule-1 (ICAM-1) regulates endothelial cell motility through a nitric oxide-dependent pathway. J Biol Chem (2004) 1.23
Screening for hepatocellular carcinoma in patients with hepatitis C cirrhosis: a cost-utility analysis. Am J Gastroenterol (2003) 1.23
Umbilical cord plasma interleukin-6 concentrations in preterm infants and risk of neonatal morbidity. Am J Obstet Gynecol (2004) 1.23
Myofibroblast differentiation and survival in fibrotic disease. Expert Rev Mol Med (2011) 1.23
The reaction between nitrite and hemoglobin: the role of nitrite in hemoglobin-mediated hypoxic vasodilation. J Inorg Biochem (2005) 1.22
The association of psychosocial stress and bacterial vaginosis in a longitudinal cohort. Am J Obstet Gynecol (2006) 1.22
The role of endothelin-1 and the endothelin B receptor in the pathogenesis of hepatopulmonary syndrome in the rat. Hepatology (2004) 1.21
Thy-1 regulates fibroblast focal adhesions, cytoskeletal organization and migration through modulation of p190 RhoGAP and Rho GTPase activity. Exp Cell Res (2004) 1.20
Loss of Thy-1 inhibits alveolar development in the newborn mouse lung. Am J Physiol Lung Cell Mol Physiol (2009) 1.19
Nerve sparing robotic extravesical ureteral reimplantation. J Urol (2008) 1.19
Antiinflammatory evaluation of alcoholic extract of galls of Quercus infectoria. J Ethnopharmacol (2004) 1.19
Maternal and transplacental pharmacokinetics of azithromycin. Am J Obstet Gynecol (2003) 1.19