Michael Tymianski

Author PubWeight™ 80.88‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A key role for TRPM7 channels in anoxic neuronal death. Cell 2003 4.46
2 Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain. Nature 2012 4.04
3 Treatment of ischemic brain damage by perturbing NMDA receptor- PSD-95 protein interactions. Science 2002 3.98
4 NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo. J Neurosci 2007 3.44
5 Glutamate receptors, neurotoxicity and neurodegeneration. Pflugers Arch 2010 2.83
6 Calcium, ischemia and excitotoxicity. Cell Calcium 2010 2.38
7 Safety and efficacy of NA-1 in patients with iatrogenic stroke after endovascular aneurysm repair (ENACT): a phase 2, randomised, double-blind, placebo-controlled trial. Lancet Neurol 2012 2.34
8 Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity. Cell Calcium 2003 2.21
9 Intracranial aneurysms: from vessel wall pathology to therapeutic approach. Nat Rev Neurol 2011 1.77
10 Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia. Nat Neurosci 2009 1.75
11 Steal physiology is spatially associated with cortical thinning. J Neurol Neurosurg Psychiatry 2010 1.73
12 The natural history and predictive features of hemorrhage from brain arteriovenous malformations. Stroke 2008 1.67
13 Inhibition of caspase-mediated apoptosis by peroxynitrite in traumatic brain injury. J Neurosci 2006 1.63
14 PDZ protein interactions underlying NMDA receptor-mediated excitotoxicity and neuroprotection by PSD-95 inhibitors. J Neurosci 2007 1.62
15 Beyond NMDA and AMPA glutamate receptors: emerging mechanisms for ionic imbalance and cell death in stroke. Trends Pharmacol Sci 2008 1.62
16 Specific targeting of pro-death NMDA receptor signals with differing reliance on the NR2B PDZ ligand. J Neurosci 2008 1.58
17 Impaired peri-nidal cerebrovascular reserve in seizure patients with brain arteriovenous malformations. Brain 2010 1.56
18 Priority setting in neurosurgery as exemplified by an everyday challenge. Can J Neurol Sci 2013 1.39
19 TRPM7 channels in hippocampal neurons detect levels of extracellular divalent cations. Proc Natl Acad Sci U S A 2007 1.37
20 Effectiveness of PSD95 inhibitors in permanent and transient focal ischemia in the rat. Stroke 2008 1.31
21 Preoperative and postoperative mapping of cerebrovascular reactivity in moyamoya disease by using blood oxygen level-dependent magnetic resonance imaging. J Neurosurg 2005 1.23
22 TRPMs and neuronal cell death. Pflugers Arch 2005 1.19
23 Ca2+-dependent induction of TRPM2 currents in hippocampal neurons. J Physiol 2009 1.19
24 Vulnerability of central neurons to secondary insults after in vitro mechanical stretch. J Neurosci 2004 1.15
25 A discriminative prediction model of neurological outcome for patients undergoing surgery of brain arteriovenous malformations. Stroke 2006 1.12
26 Molecular mechanisms underlying specificity of excitotoxic signaling in neurons. Curr Mol Med 2004 1.11
27 Three-dimensional in vivo modeling of vestibular schwannomas and surrounding cranial nerves with diffusion imaging tractography. Neurosurgery 2011 1.10
28 Involvement of caspase-6 and caspase-8 in neuronal apoptosis and the regenerative failure of injured retinal ganglion cells. J Neurosci 2011 1.09
29 Nonhuman primate models of stroke for translational neuroprotection research. Neurotherapeutics 2012 1.05
30 Impaired cerebrovascular reactivity with steal phenomenon is associated with increased diffusion in white matter of patients with Moyamoya disease. Stroke 2010 1.04
31 Novel treatment of excitotoxicity: targeted disruption of intracellular signalling from glutamate receptors. Biochem Pharmacol 2003 1.02
32 A translational paradigm for the preclinical evaluation of the stroke neuroprotectant Tat-NR2B9c in gyrencephalic nonhuman primates. Sci Transl Med 2012 1.02
33 Impact of extracranial-intracranial bypass on cerebrovascular reactivity and clinical outcome in patients with symptomatic moyamoya vasculopathy. Stroke 2011 0.99
34 Cellular schwannoma of the abducens nerve: case report and review of the literature. Clin Neurol Neurosurg 2009 0.98
35 Neuroprotection by freezing ischemic penumbra evolution without cerebral blood flow augmentation with a postsynaptic density-95 protein inhibitor. Stroke 2011 0.98
36 TRPM7 and ischemic CNS injury. Neuroscientist 2005 0.95
37 Impact of individual intracranial arterial aneurysm morphology on initial obliteration and recurrence rates of endovascular treatments: a multivariate analysis. J Neurosurg 2010 0.93
38 Surgical revascularization reverses cerebral cortical thinning in patients with severe cerebrovascular steno-occlusive disease. Stroke 2011 0.91
39 Symptomatic enlargement of an occluded giant carotido-ophthalmic aneurysm after endovascular treatment: the vasa vasorum theory. Acta Neurochir (Wien) 2009 0.90
40 Severely impaired cerebrovascular reserve in patients with cerebral proliferative angiopathy. J Neurosurg Pediatr 2011 0.90
41 Analysis of cost related to clinical and angiographic outcomes of aneurysm patients enrolled in the international subarachnoid aneurysm trial in a North American setting. Neurosurgery 2005 0.89
42 The contribution of imaging in diagnosis, preoperative assessment, and follow-up of moyamoya disease: a review. Neurosurg Focus 2009 0.88
43 Enhanced vulnerability to NMDA toxicity in sublethal traumatic neuronal injury in vitro. J Neurotrauma 2003 0.88
44 Aspirin as a promising agent for decreasing incidence of cerebral aneurysm rupture. Stroke 2011 0.85
45 Dependence of NMDA/GSK-3β mediated metaplasticity on TRPM2 channels at hippocampal CA3-CA1 synapses. Mol Brain 2011 0.84
46 Modulation of NMDAR subunit expression by TRPM2 channels regulates neuronal vulnerability to ischemic cell death. J Neurosci 2013 0.84
47 Translating promising preclinical neuroprotective therapies to human stroke trials. Expert Rev Cardiovasc Ther 2011 0.84
48 Intraoperative biplanar rotational angiography during neurovascular surgery. Technical note. J Neurosurg 2009 0.82
49 Assessment of extracranial-intracranial bypass patency with 64-slice multidetector computerized tomography angiography. Neuroradiology 2009 0.81
50 A safety, length of stay, and cost analysis of minimally invasive microsurgery for anterior circulation aneurysms. Acta Neurochir (Wien) 2014 0.81
51 Overview of the current role of endovascular and surgical treatment in spinal dural arteriovenous fistulas. Neurosurg Focus 2009 0.81
52 The use of propidium iodide to assess excitotoxic neuronal death in primary mixed cortical cultures. Methods Mol Biol 2007 0.81
53 Multidisciplinary care of occipital arteriovenous malformations: effect on nonhemorrhagic headache, vision, and outcome in a series of 135 patients. Clinical article. J Neurosurg 2010 0.81
54 Challenges in the management of ruptured and unruptured brainstem arteriovenous malformations: outcome after conservative, single-modality, or multimodality treatments. Neurosurgery 2012 0.81
55 Novel concepts in excitotoxic neurodegeneration after stroke. Expert Rev Mol Med 2003 0.79
56 Pituitary adenoma associated with intraventricular meningioma: case report. Skull Base 2007 0.79
57 Advances in vascular neurosurgery 2010. Stroke 2011 0.79
58 Early identification of brain tissue at risk for delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage. Acta Neurochir Suppl 2015 0.77
59 BOLD MRI and early impairment of cerebrovascular reserve after aneurysmal subarachnoid hemorrhage. J Magn Reson Imaging 2013 0.77
60 Impaired cerebrovascular reactivity in the early phase of subarachnoid hemorrhage in good clinical grade patients does not predict vasospasm. Acta Neurochir Suppl 2015 0.76
61 Transmastoid partial labyrinthectomy for brainstem vascular lesions: clinical outcomes and assessment of postoperative cochleovestibular function. Skull Base 2006 0.75
62 Day surgery craniotomy for unruptured cerebral aneurysms: a single center experience. J Neurosurg Anesthesiol 2014 0.75
63 Symptomatic non-atherosclerotic bilateral extracranial vertebral artery occlusion treated with extracranial to intracranial bypass: case report. Arq Neuropsiquiatr 2006 0.75
64 Neuroprotective strategies in epilepsy. Adv Exp Med Biol 2002 0.75
65 Postoperative assessment of clipped aneurysms with 64-slice computerized tomography angiography. Neurosurgery 2010 0.75
66 Microsurgical glue embolectomy of the middle cerebral artery following embolization of a maxillofacial arteriovenous malformation. J Clin Neurosci 2011 0.75
67 805 A Single-Center, Prospective Analysis of the Natural History of Hemorrhage from Brain Arteriovenous Malformations with or without Associated Aneurysms. Neurosurgery 2005 0.75
68 Advances in stroke: vascular neurosurgery. Stroke 2013 0.75
69 Peptide action in stroke therapy. Expert Opin Biol Ther 2003 0.75