Published in J Struct Biol on December 24, 2008
Building blocks of the apoptotic pore: how Bax and Bak are activated and oligomerize during apoptosis. Cell Death Differ (2013) 1.54
Direct activation of full-length proapoptotic BAK. Proc Natl Acad Sci U S A (2013) 1.53
BID-induced structural changes in BAK promote apoptosis. Nat Struct Mol Biol (2013) 1.45
Tyrosine dephosphorylation is required for Bak activation in apoptosis. EMBO J (2010) 1.09
Bak Conformational Changes Induced by Ligand Binding: Insight into BH3 Domain Binding and Bak Homo-Oligomerization. Sci Rep (2012) 0.96
A new view of the lethal apoptotic pore. PLoS Biol (2012) 0.94
"Licensed to kill": tyrosine dephosphorylation and Bak activation. Cell Cycle (2011) 0.88
The deadly landscape of pro-apoptotic BCL-2 proteins in the outer mitochondrial membrane. FEBS J (2016) 0.78
Identification of an activation site in Bak and mitochondrial Bax triggered by antibodies. Nat Commun (2016) 0.76
Finding the missing link: disulfide-containing proteins via a high-throughput proteomics approach. Proteomics (2013) 0.75
Structural biology of the intrinsic cell death pathway: what do we know and what is missing? Comput Struct Biotechnol J (2012) 0.75
Frequent pathway mutations of splicing machinery in myelodysplasia. Nature (2011) 11.44
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res (2004) 9.18
Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice. Science (2003) 8.65
The Physcomitrella genome reveals evolutionary insights into the conquest of land by plants. Science (2007) 8.12
Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat Genet (2003) 7.98
Mapping human genetic diversity in Asia. Science (2009) 7.40
Integrative annotation of 21,037 human genes validated by full-length cDNA clones. PLoS Biol (2004) 7.17
Crystal structure of a bacterial RNA polymerase holoenzyme at 2.6 A resolution. Nature (2002) 6.74
A transcription factor response element for gene expression during circadian night. Nature (2002) 6.55
Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer. Mol Cell (2006) 6.09
A test of enhancing model accuracy in high-throughput crystallography. J Struct Funct Genomics (2005) 5.96
The medaka draft genome and insights into vertebrate genome evolution. Nature (2007) 5.77
Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa. Cell (2006) 5.70
Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains. Cell (2002) 5.64
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Genome Res (2005) 5.22
Genome sequence of the ultrasmall unicellular red alga Cyanidioschyzon merolae 10D. Nature (2004) 5.08
An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors. Mol Cell (2003) 5.06
Curved EFC/F-BAR-domain dimers are joined end to end into a filament for membrane invagination in endocytosis. Cell (2007) 4.73
Integrated molecular analysis of clear-cell renal cell carcinoma. Nat Genet (2013) 4.61
Let-7 microRNA-mediated mRNA deadenylation and translational repression in a mammalian cell-free system. Genes Dev (2007) 4.35
DBTSS: DataBase of human Transcriptional Start Sites and full-length cDNAs. Nucleic Acids Res (2002) 4.29
Human Proteinpedia enables sharing of human protein data. Nat Biotechnol (2008) 4.21
Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species. Proc Natl Acad Sci U S A (2010) 4.18
Protein production and purification. Nat Methods (2008) 3.97
DBTSS, DataBase of Transcriptional Start Sites: progress report 2004. Nucleic Acids Res (2004) 3.73
Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways. Oncogene (2003) 3.53
A vertebrate RNA-binding protein Fox-1 regulates tissue-specific splicing via the pentanucleotide GCAUG. EMBO J (2003) 3.44
Regulation through the secondary channel--structural framework for ppGpp-DksA synergism during transcription. Cell (2004) 3.39
The landscape of C. elegans 3'UTRs. Science (2010) 3.32
ATP binding by glutamyl-tRNA synthetase is switched to the productive mode by tRNA binding. EMBO J (2003) 3.14
DBTSS: database of transcription start sites, progress report 2008. Nucleic Acids Res (2007) 3.11
Chromatin-associated periodicity in genetic variation downstream of transcriptional start sites. Science (2008) 3.10
Crystal structure of the cytoskeleton-associated protein glycine-rich (CAP-Gly) domain. J Biol Chem (2002) 3.01
A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity. Nature (2013) 2.74
DKK1, a negative regulator of Wnt signaling, is a target of the beta-catenin/TCF pathway. Oncogene (2004) 2.73
Structural basis for orthogonal tRNA specificities of tyrosyl-tRNA synthetases for genetic code expansion. Nat Struct Biol (2003) 2.71
Estimation of the time-course of dopamine D2 receptor occupancy in living human brain from plasma pharmacokinetics of antipsychotics. Int J Neuropsychopharmacol (2004) 2.64
Structural basis for substrate selection by t7 RNA polymerase. Cell (2004) 2.62
Structural basis for interaction of the ribosome with the switch regions of GTP-bound elongation factors. Mol Cell (2007) 2.62
Structural basis for transcription regulation by alarmone ppGpp. Cell (2004) 2.60
Thyrotrophin in the pars tuberalis triggers photoperiodic response. Nature (2008) 2.60
Vitrectomy without laser treatment or gas tamponade for macular detachment associated with an optic disc pit. Ophthalmology (2012) 2.59
Structure of a T7 RNA polymerase elongation complex at 2.9 A resolution. Nature (2002) 2.57
DBTSS: DataBase of Human Transcription Start Sites, progress report 2006. Nucleic Acids Res (2006) 2.52
Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive Sendai virus vectors. Proc Natl Acad Sci U S A (2011) 2.51
Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding. Immunity (2012) 2.47
The functional consequences of alternative promoter use in mammalian genomes. Trends Genet (2008) 2.47
An unnatural hydrophobic base pair system: site-specific incorporation of nucleotide analogs into DNA and RNA. Nat Methods (2006) 2.46
Construction of a full-length enriched and a 5'-end enriched cDNA library using the oligo-capping method. Methods Mol Biol (2003) 2.45
Different electrostatic potentials define ETGE and DLG motifs as hinge and latch in oxidative stress response. Mol Cell Biol (2007) 2.38
5'-end SAGE for the analysis of transcriptional start sites. Nat Biotechnol (2004) 2.34
Adding l-lysine derivatives to the genetic code of mammalian cells with engineered pyrrolysyl-tRNA synthetases. Biochem Biophys Res Commun (2008) 2.29
Crystal structure of hypothetical protein TTHB192 from Thermus thermophilus HB8 reveals a new protein family with an RNA recognition motif-like domain. Protein Sci (2006) 2.29
Alternative tertiary structure of tRNA for recognition by a posttranscriptional modification enzyme. Cell (2003) 2.29
Genome sequence of an Australian kangaroo, Macropus eugenii, provides insight into the evolution of mammalian reproduction and development. Genome Biol (2011) 2.18
Preparation of Escherichia coli cell extract for highly productive cell-free protein expression. J Struct Funct Genomics (2004) 2.14
Multistep engineering of pyrrolysyl-tRNA synthetase to genetically encode N(epsilon)-(o-azidobenzyloxycarbonyl) lysine for site-specific protein modification. Chem Biol (2008) 2.13
The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response. Nat Immunol (2012) 2.11
Promoter prediction analysis on the whole human genome. Nat Biotechnol (2004) 2.08
The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts. Nucleic Acids Res (2007) 2.07
Reconstitution reveals the functional core of mammalian eIF3. EMBO J (2007) 2.06
A B-box 2 surface patch important for TRIM5alpha self-association, capsid binding avidity, and retrovirus restriction. J Virol (2009) 2.03
Crystal structure of bacterial RNA polymerase bound with a transcription inhibitor protein. Nature (2010) 2.01
Parkin binds the Rpn10 subunit of 26S proteasomes through its ubiquitin-like domain. EMBO Rep (2003) 2.01
A computational model on the modulation of mitogen-activated protein kinase (MAPK) and Akt pathways in heregulin-induced ErbB signalling. Biochem J (2003) 2.00
Crystal structure of the homologous-pairing domain from the human Rad52 recombinase in the undecameric form. Mol Cell (2002) 1.98
Structure of the oncoprotein gankyrin in complex with S6 ATPase of the 26S proteasome. Structure (2007) 1.97
Inference of S-system models of genetic networks using a cooperative coevolutionary algorithm. Bioinformatics (2004) 1.96
Interaction of Era with the 30S ribosomal subunit implications for 30S subunit assembly. Mol Cell (2005) 1.93
Effects of raloxifene on bone metabolism in hemodialysis patients with type 2 diabetes. Int J Endocrinol Metab (2012) 1.90
Structural basis of the substrate-specific two-step catalysis of long chain fatty acyl-CoA synthetase dimer. J Biol Chem (2004) 1.89
Rate of evolution in brain-expressed genes in humans and other primates. PLoS Biol (2007) 1.87
The crystal structure of leucyl-tRNA synthetase complexed with tRNALeu in the post-transfer-editing conformation. Nat Struct Mol Biol (2005) 1.87
Estrogen-related receptor-α is a metabolic regulator of effector T-cell activation and differentiation. Proc Natl Acad Sci U S A (2011) 1.86
Aortic regurgitation after valve-sparing aortic root replacement: modes of failure. Ann Thorac Surg (2011) 1.85
Aminoacylation complex structures of leucyl-tRNA synthetase and tRNALeu reveal two modes of discriminator-base recognition. Nat Struct Mol Biol (2005) 1.82
Increased Ras expression and caspase-independent neuroblastoma cell death: possible mechanism of spontaneous neuroblastoma regression. J Natl Cancer Inst (2002) 1.78